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World Journal of Clinical Cases 2020年第24期8卷 6432-6436页

作者： Albert Youngwoo Jang soon yong suh Department of Cardiology Gachon University Gil Medical CenterIncheon 21565South Korea Department of Cardiology Gachon University Gil HospitalIncheon 21565South Korea

BACKGROUND Wet cupping (WC) is a traditional therapy of skin suction-assisted bloodlettingthat is widely used in modern alternative medicine in Asia and the Middle ***, we report the case of a male who presented with ST-elevation myocardialinfarction (STEMI) and life-threatening anemia and underwent excessive *** SUMMARY A 55-year-old male presented with chest pain (30 min) and dyspnea (3 wk). Hisinitial electrocardiogram suggested STEMI in the anterior wall. Furthermore, hislaboratory results showed severe anemia with a hemoglobin level of 4.1 g/dL. Ofnote, the patient underwent regular WC therapy for chronic back pain, which hehad recently intensified. His WC practice resulted in life-threatening anemia andeventually STEMI. Percutaneous coronary intervention in the left anteriordescending artery was performed to treat the STEMI. His dyspnea dramaticallyimproved after the transfusion, and his hemoglobin level returned to 14.8 g/dLwithin 2 mo after discharge. He has been uneventful for the last seven years *** The current case demonstrates that excessive WC without adequate medicalmonitoring can result in severe anemia, which can further develop into STEMI.

关键词： Bloodletting ST-elevation myocardial infarction Anemia Cupping Wet cupping Case report

ST-segment elevation myocardial infarction in Kawasaki disease:A case report and review of literature

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World Journal of Clinical Cases 2022年第26期10卷 9368-9377页

作者： Joonpyo Lee Jeongduk Seo yong Hoon Shin Albert Youngwoo Jang soon yong suh Division of Cardiology Department of Internal MedicineGachon UniversityGil Medical CenterIncheon 21565South Korea

BACKGROUND Kawasaki disease(KD)is an acute self-limiting febrile vasculitis that occurs during childhood and can cause coronary artery aneurysm(CAA).CAAs are associated with a high rate of adverse cardiovascular *** SUMMARY A Korean 35-year-old man with a 30-year history of KD presented to the emergency room with chest *** coronary angiography was performed as ST-segment elevation in the inferior leads was observed on the *** aneurysm of the left circumflex(LCX)coronary artery was found with massive thrombi within.A drug-eluting 4.5 mm 23 mm-sized stent was inserted into the occluded area without *** maximal diameter of the LCX was 6.0 mm with a Z score of 4.7,suggestive of a small aneurysm considering his age,sex,and body surface *** further present a case series of 19 patients with KD,including the current patient,presenting with acute coronary syndrome(ACS).Notably,none of the cases showed Z scores;only five patients(26%)had been regularly followed up by a physician,and only one patient(5.3%)was being treated with antithrombotic therapy before ACS *** For KD presenting with ACS,regular follow up and medical therapy may be crucial for improved outcomes.

关键词： Kawasaki disease Acute coronary syndrome ST elevation myocardial infarction Coronary angiography Percutaneous coronary intervention Case report

Acute myocardial infarction after initially diagnosed with unprovoked venous thromboembolism: A case report

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World Journal of Clinical Cases 2023年第30期11卷 7497-7501页

作者： Jeongduk Seo Joonpyo Lee yong Hoon Shin Albert Youngwoo Jang soon yong suh Department of Cardiology Gachon University Gil Medical CenterIncheon 405-760South Korea

BACKGROUND Protein C deficiency is typically associated with venous thromboembolism;however,arterial thrombosis has been reported in several *** report the case of a patient with pulmonary thromboembolism and deep vein thrombosis following acute myocardial infarction with high thrombus *** SUMMARY A 40-year-old man was diagnosed with pulmonary thromboembolism and deep vein thrombosis without any provoking *** patient was treated with anticoagulants for six months,which were then *** months after the discontinuation of anticoagulant therapy,the patient was hospitalized with chest pain and diagnosed with acute myocardial infarction with high thrombus *** tests revealed protein C deficiency associated with *** patient was treated with anticoagulants combined with dual antiplatelet agents for 1 year after percutaneous coronary intervention,and no recurrent events were reported during a follow-up period of 5 *** Recurrent thromboembolic events including acute myocardial infarction with thrombus should be considered an alarming sign of thrombophilia.

关键词： Venous thromboembolism thrombophilia Protein C deficiency ST elevation myocardial infarction Anticoagulation Case report

Iatrogenic aortic dissection during right transradial intervention in a patient with aberrant right subclavian artery:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9897-9903页

作者： Kyungeun Ha Albert Youngwoo Jang yong Hoon Shin Joonpyo Lee Jeongduk Seo Seok In Lee Woong Chol Kang soon yong suh Division of Cardiology Department of Internal MedicineYonsei University College of Medicine50 Yonsei-roSeodaemun-guSeoulSouth Korea Division of Cardiology Department of Internal MedicineGil Medical CenterGachon University College of MedicineIncheonSouth Korea Department of Thoracic and Cardiovascular Surgery Gil Medical CenterGachon University College of MedicineIncheonIncheonSouth Korea

BACKGROUND Aberrant right subclavian artery(ARSA)is the most common congenital anomaly of the aortic *** patients having such anomalies receive transradial intervention(TRI),aortic dissection(AD)may ***,we discuss a case of iatrogenic type B AD occurring during right TRI in an ARSA patient,that was later salvaged by percutaneous *** SUMMARY A 73-year-old man presented to our hospital with intermittent chest *** computed tomography(CT)angiography revealed significant stenosis in the left anterior descending *** coronary angiography was performed via the right radial artery without ***,we were unable to advance the guiding catheter past the ostium of the right subclavian artery to the aortic arch for percutaneous coronary intervention,while the guidewire tended to go down the descending *** patient suddenly complained of chest and back *** CT aortography revealed type B AD propagating to the left renal artery(RA)with preserved renal ***,after 2 d,the patient suddenly complained of right lower limb pain where the femoral pulse was suddenly ***-up CT indicated further progression of dissection to the right external iliac artery(EIA)and left RA with limited *** performed percutaneous angioplasty of the right EIA and left RA without ***-up CT aortography at 8 mo showed optimal *** A caution is required during right TRI in ARSA to avoid *** angioplasty can be a treatment option.

关键词： Aberrant subclavian artery Coronary angiography Aortic dissection Aortography Percutaneous transluminal angioplasty Case report

Tidal effects based on a GUP-induced effective metric

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Communications in Theoretical Physics 2024年第9期76卷 65-74页

作者： soon-Tae Hong yong-Wan Kim Young-Jai Park Center for Quantum Spacetime and Department of Physics Sogang University Department of Physics and Research Institute of Physics and Chemistry Jeonbuk National University Department of Physics Sogang University

In this paper, we study tidal forces in the Schwarzschild black hole, whose metric explicitly includes a generalized uncertainty principle(GUP) effect. We also investigate interesting features of the geodesic equations and tidal effects that are dependent on the GUP parameter αrelated to a minimum length. Then, by solving the geodesic deviation equations explicitly with appropriate boundary conditions, we show that α in the effective metric affects both the radial and angular components of the geodesic equation, particularly near the singularities.

关键词： effective metric generalized uncertainty principle geodesic deviation equation

New insights into ATR inhibition in muscle invasive bladder cancer:The role of apolipoprotein B mRNA editing catalytic subunit 3B

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Oncology Research 2024年第6期32卷 1021-1030页

作者： HYUNHO KIM UIJU CHO SOOK HEE HONG HYUNG soon PARK IN-HO KIM HO JUNG AN BYOUNG yong SHIM JIN HYOUNG KANG Division of Medical Oncology Department of Internal MedicineSt.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwonKorea Department of Pathology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwonKorea Division of Medical Oncology Department of Internal MedicineSeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulKorea

Background:Apolipoprotein B mRNA editing catalytic polypeptide(APOBEC),an endogenous mutator,induces DNA damage and activates the ataxia telangiectasia and Rad3-related(ATR)-checkpoint kinase 1(Chk1)*** cisplatin-based therapy is the mainstay for muscle-invasive bladder cancer(MIBC),it has a poor survival ***,this study aimed to evaluate the efficacy of an ATR inhibitor combined with cisplatin in the treatment of APOBEC catalytic subunit 3B(APOBEC3B)expressing ***:Immunohistochemical staining was performed to analyze an association between APOBEC3B and ATR in patients with *** APOBEC3B expression in MIBC cell lines was assessed using real-time polymerase chain reaction and western blot *** blot analysis was performed to confirm differences in phosphorylated Chk1(pChk1)expression according to the APOBEC3B *** viability and apoptosis analyses were performed to examine the anti-tumor activity of ATR inhibitors combined with ***:There was a significant association between APOBEC3B and ATR expression in the tumor tissues obtained from patients with *** with higher APOBEC3B expression showed higher pChk1 expression than cells expressing low APOBEC3B *** treatment of ATR inhibitor and cisplatin inhibited cell growth in MIBC cells with a higher APOBEC3B *** to cisplatin single treatment,combination treatment induced more apoptotic cell death in the cells with higher APOBEC3B ***:Our study shows that APOBEC3B’s higher expression status can enhance the sensitivity of MIBC to cisplatin upon ATR *** result provides new insight into appropriate patient selection for the effective application of ATR inhibitors in MIBC.

关键词： Apolipoprotein B mRNA editing catalytic polypeptide(APOBEC) Ataxia telangiectasia and Rad3-related(ATR) Bladder cancer DNA damage response DNA replication stress

Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma

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World Journal of Gastroenterology 2010年第17期16卷 2158-2162页

作者： Hyung soon Park Yu Jin Kim Woo Ick Yang Chang Ok suh yong Chan Lee Department of Internal Medicine Yonsei University College of Medicine120-752 SeoulSouth Korea Department of Pathology Yonsei University College of Medicine120-752 SeoulSouth Korea Department of Radiation Oncology Yonsei University College of Medicine120-752 SeoulSouth Korea

AIM: To investigate treatment outcome of Helicobacter pylori (*** )-negative low-grade gastric mucosaassociated lymphoid tissue (MALT) ***: In this study,we retrospectively reviewed the clinical outcome and clinicopathologic factors of stage Ⅰ E *** -negative low-grade gastric MALT lymphoma cases from August 1998 to June ***: A total of eleven patients with *** -negative low-grade gastric MALT lymphoma were enrolled in the study and received *** eradication treatment and/or radiotherapy or excisional *** remission (CR) of gastric MALT lymphoma was achieved in all *** time to CR was 1-66 mo (median,1 mo).CONCLUSION: Eradication therapy may be offered as an initial treatment option even in cases of localized *** -negative gastric MALT lymphoma.

关键词： Anti-bacterial agents Helicobacter pylori Mucosa-associated lymphoid tissue lymphoma Radiotherapy Stomach

China's agriculture green development: from concept to actions

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Frontiers of Agricultural Science and Engineering 2024年第1期11卷 20-34页

作者： Haixing ZHANG Yuan FENG Yanxiang JIA Pengqi LIU yong HOU Jianbo SHEN Qichao ZHU Fusuo ZHANG National Academy of Agriculture Green Development China Agricultural UniversityBeijing 100193China College of Resources and Environmental Sciences China Agricultural UniversityBeijing 100193China Environmental Economics and Natural Resources Group Wageningen University and ResearchP.O.Box 81306700 EW Wageningenthe Netherlands

China has initiated a green transformation plan in 2015, which was soon applied to agriculture, known as the agriculture green development(AGD)initiative, with the goals of achieving food security, high resource use efficiency, and an ecofriendly environment. To assess the agricultural transformation from 1997 to 2020, this paper proposes a national-scale indicator system consisting three dimensions(socioeconomic, food production and eco-environmental) and ten sub-dimensions to quantify the AGD *** study showed that AGD score in China was at a moderate level during 1997–2010, scoring 40 out of 100. During this stage, decreased scores in the sub-dimensions of resource consumption, environmental quality, and environmental cost have offset the improvement in the socioeconomic dimension, resulting in fluctuated scores around 40. In the second stage(2011–2020), China's AGD score improved but still at moderate level, scoring an average of 46.3, with each dimension increasing by 5.3%–25.0%. These results indicate that China has made progress in the agricultural transformation, transitioning from conceptualization to actions through the implementation of various policies and projects. However, the study emphasizes the need for more effort to address the insufficient and unbalanced development, along with the growing eco-environmental challenges, especially the trade-offs among dimensions.

关键词： Agricultural transformation agriculture green development historical trend indicator system theoretical conception

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A Note on the Stability of Jordan Triple Higher Ring Derivations

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Acta Mathematica Sinica,English Series 2009年第12期25卷 1975-1986页

作者： Jaiok ROH yong-Soo JUNG Ick-soon CHANG Department of Mathematics Hallym University Department of Mathematics Sunmoon University Department of Mathematics Mokwon University

In the present paper, we establish the stability and the superstability of a functional inequality corresponding to the functional equation fn（xyx） = ∑i＋j＋k=n fi（x）fj （y）fk（x）. In addition, we take account ... 详细信息

关键词： functional inequality Jordan triple higher ring derivation stability radical range

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Velocity and Sediment Concentration Profiles in Sediment-Laden Flows

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海洋工程：英文版 2004年第2期18卷 229-244页

作者：杨树清 soon-Keat TAN Siow-yong LIM Maritime Research Center School of Civil and Environmental Engineering

A theoretical analysis of velocity profiles in sediment-laden flows is presented by means of Prandtl-Karman mixing length theorem. The study shows that the upward velocity of liquid-phase caused by settling sediment leads to the invalidity of the log-law and Rouse equation. The theoretical analysis takes into account the upward velocity and shows: 1) the mean velocity in sediment-laden flows follows the log-law, but the Karman constant reduces in the main flow region, 2) sediment concentration reduces the mixing length of fluid particles, 3) flow resistance reduces with the presence of sediment concentration, and 4) the sediment concentration profile deviates from the well know Rouse equation. The experimental data agree well with the equations derived on the basis of non-zero wall velocity. It is found that the wall-normal velocity should not be neglected for density gradient flows because it induces more than for pure water flows.

关键词： sediment concentration reduction of Karman constant log-law sediment concentration distribution

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