检索结果-南通市图书馆

Wave prediction in a port using a fully nonlinear Boussinesq wave model

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2019年第7期38卷 36-47页

作者： Young-Kwang Choi Seung-Nam Seo Jin-Yong Choi Fengyan Shi Kwang-soon park Civil and Architectural Engineering Department KEPCO Engineering and ConstructionGimcheon-si 39660Republic of Korea Task Force for Construction of RV ISABU Support Facility Korea Institute of Ocean Science and TechnologyBusan Metropolitan City 49111Republic of Korea Operational Oceanography Research Center Korea Institute of Ocean Science and TechnologyBusan Metropolitan City 49111Republic of Korea Center for Applied Coastal Research University of DelawareNewark DE 19716USA

A wave forecasting system using FUNWAVE-TVD which is based on the fully nonlinear Boussinesq equations by Chen(2006)was developed to provide an accurate wave prediction in the Port of Busan,South *** system is linked to the Korea Operational Oceanographic System(KOOS)developed by park et al.(2015).The computational domain covers a region of 9.6 km×7.0 km with a grid size of 2 m in both directions,which is sufficient to resolve short waves and dominant sea *** total number of grid points exceeds 16 millions,making the model computational *** provide real-time forecasting,an interpolation method,which is based on pre-calculated results of FUNWAVE-TVD and SWAN forecasting results at the FUNWAVE-TVD offshore boundary,was used.A total of 45 cases were pre-calculated,which took 71 days on 924 computational cores of a Linux cluster *** wave generation and propagation from the deep water were computed using the SWAN in *** results provided a boundary condition for the FUNWAVE-TVD forecasting *** verify the model,wave observations were conducted at three locations inside the port in a time period of more than 7 months.A model/model comparison between FUNWAVE-TVD and SWAN was also carried *** is found that,FUNWAVE-TVD improves the forecasting results significantly compared to SWAN which underestimates wave heights in sheltered areas due to incorrect physical mechanism of wave diffraction,as well as large wave heights caused by wave reflections inside the port.

关键词： real-time wave forecasting FUNWAVE-TVD SWAN KOOS wave observations wave diffraction

Comparison of the efficacy and safety of once-daily dosing and on-demand use of udenafil for type 2 diabetic patients with erectile dysfunction

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2015年第1期17卷 143-148,I0011,I0012页

作者： soon Hyun park Sung Woo park Bong Yun Cha Ie Byung park Kyung Wan Min Yeon Ah Sung Tae Hwa Kim Jae Min Lee Kang Seo park Department of Internal Medicine Eulji University School of Medicine Daejeon 302-799 South Korea Department of Endocrinology and Metabolism Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seou1110-746 South Korea Department of Endocrinology and Metabolism College of Medicine the Catholic University of Korea Seou1137-701 South Korea Department of Internal Medicine Gachon University of Medicine and Science Graduate School of Medicine Incheon 405-760 South Korea Department of Internal Medicine Eulji University School of Medicine Seou1139-872 South Korea Department of Endocrinology Ewha Woman's University School of Medicine Seoul 158-710 South Korea Department of Internal Medicine College of Medicine Hanyang University Seoul 133-792 South Korea.

We compared the efficacy and safety between once-daily dosing and on-demand use of udenafil for type 2 diabetic patients with erectile dysfunction （ED）. A multi-center, randomized, open-label, parallel-group, 12-week study was conducted. 161 patients who improved with on-demand 200 mg of udenafil according to Sexual Encounter Profile （SEP） diary Question 2 and 3 （Q2 and Q3） were randomized into 200 mg on-demand （n = 80） or 50 mg once-daily （n = 81） dosing groups for 8 weeks. The dosing period was followed by a 4-week treatment-free period. The primary efficacy endpoint was the change of the International Index of Erectile Function （IIEF） erectile function domain （EFD） score. The secondary efficacy endpoints included changes to the SEP diary Q2, Q3, IIEF Q3, Q4, other domains of IIEF, Global Assessment Question, and shift to the normal rate （EFD 〉 26）. Vascular endothelial markers were also assessed. The IIEF-EFD score of both groups improved after 8 weeks of treatment （P 〈 0.0001）. There was no statistically significant difference between two groups. Improvement was not maintained after the treatment-free follow-up period. Similar results were observed in the secondary efficacy endpoints. There was also no significant difference in vascular endothelial markers. Daily udenafil was well-tolerated, and there was no significant difference in the adverse drug reactions and adverse events between the two groups. Flushing and headache were the most frequent adverse events. Both regimens improved ED in diabetic patients and were well-tolerated. Further studies are needed to assess the effect of daily udenafil treatment in diabetic patients.

关键词： erectile dysfunction International Index of Erectile Function once-daily dosing ptiosphodiesterase type 5 inhibitor type 2 diabetes mellitus udenafil

Experiment on Dust Flux During Duststorm Periods over Desert Area

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta meteorologica Sinica 2008年第2期22卷 239-247页

作者：张宏升朱好彭艳康凌陈家宜 soon-Ung park Center of Sino-Korcan Atmospheric Sciences Department of Atmospheric SciencesPeking University Center of Sino-Korean Atmospheric Sciences Department of Atmospheric SciencesPeking University Center of Sino-Korean Atmospheric Sciences Department of Atmospheric SciencesSeoul National UniversitySeoul 151-742Korea

The present study investigates the characteristics of turbulent transfer and the conditions for dust emission and transport using the dust concentration and micrometeorological data obtained during dust events occurring in the spring of 2004 over the Hunshandake desert area. The turbulent exchange coefficients and turbulent fluxes of momentum and heat are calculated. The relationships between dust flux, friction velocity, and wind speed are also explored. The results show that thermal turbulence is dominant during daytime of non-dusty days. The dynamic turbulence increases obviously and the sensible heat flux reduces by different degrees during dust events. There is an efficient downward transfer of momentum before duststorm occurrence, and both the dynamic turbulence and the thermal turbulence are important in the surface layer. The dynamic turbulence even exceeds the thermal turbulence during severe duststorm events. The values of dust flux vary in the range of -5 5, -30 30, and -200-300 μg m^-2 s^-1 during non-dusty days, blowing dust, and duststorm events, respectively. A slight upward transport of dust is observed during non-dusty days. The dust flux gradually varies from positive to negative during duststorm periods, which indicates the time evolution of dust events from dust rising to stably suspending and then deposition. The dust flux is found to be proportional to u＊^3. The threshold values of wind speed and friction velocity are about 6 and 0.4 m s^-1, respectively.

关键词： turbulent transfer dust flux threshold friction velocity dust event Hunshandake desert area

ELK3-ID4 axis governs the metastatic features of triple negative breast cancer

在线全文

学校读者我要写书评

暂无评论

Oncology Research 2024年第1期32卷 127-138页

作者： JIN-HO CHOI JOO DONG park SEUNG HEE CHOI EUN-SU KO HYE JUNG JANG KYUNG-soon park Department of Biomedical Science CHA UniversitySeongnamKorea

Purpose:Cancer cell metastasis is a multistep process,and the mechanism underlying extravasation remains ***3 is a transcription factor that plays a crucial role in regulating various cellular processes,including cancer *** on the finding that ELK3 promotes the metastasis of triple-negative breast cancer(TNBC),we investigated whether ELK3 regulates the extravasation of TNBC by forming the ELK3-ID4 ***4 functions as a transcriptional regulator that interacts with other transcription factors,inhibiting their activity and subsequently influencing various biological processes associated with cell differentiation,survival,growth,and ***:We assessed the correlation between the expression of ELK3 and that of ID4 in TNBCs using bioinformatics analyses,QRT-PCR,western blot analysis,luciferase reporter assays,and chromatin ***,adhesion,invasion,and lung metastasis assays were employed to determine whether the ELK3-ID4 axis regulates the metastatic features of ***:We found that ELK3 binds directly to a binding motif close to the ID4 promoter to repress promoter *** expression of E-cadherin in TNBC was regulated by the ELK3-ID4 *** vitro and in vivo analyses showed that inhibiting ID4 expression in ELK3-knockdown MDA-MB-231(ELK3KD)cells restored the ability to extravasate and ***:The results indicate that the ELK3 regulates ID4 promoter activity,and that the ELK3-ID4 axis regulates the metastatic characteristics of TNBC ***,the data suggest that the ELK3-ID4 axis regulates metastasis of TNBCs by modulating expression of E-cadherin.

关键词： E-cadherin Extravasation Colonization

Methane Emission from Rice Fields:Necessity for Molecular Approach for Mitigation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2024年第2期31卷 159-178页

作者： Sujeevan RAJENDRAN Hyeonseo park Jiyoung KIM soon Ju park Dongjin SHIN Jong-Hee LEE Young Hun SONG Nam-Chon PAEK Chul Min KIM Department of Horticulture Industry Wonkwang UniversityIksan 54538Korea Plant Molecular Biology and Biotechnology Research Center Gyeongsang National UniversityJinju 52828Korea Department of Southern Area Crop Science National Institute of Crop ScienceMiryang 50424Korea Department of Agricultural Biotechnology Seoul National UniversitySeoul 08826Korea Department of Plant Science Plant Genomics and Breeding InstituteResearch Institute of Agriculture and Life SciencesSeoul National UniversitySeoul 08826Korea

Anthropogenic methane emissions are a leading cause of the increase in global averagetemperatures,often referred to as global *** soils play a significant role in methaneproduction,where the anaerobic conditions promote the production of methane by *** fields contribute a considerable portion of agricultural methane emissions,as riceplants provide both factors that enhance and limit methane *** plants harbor both methaneproducingand methane-oxidizing *** from rice roots provide source for methaneproduction,while oxygen delivered from the root aerenchyma enhances methane *** haveshown that the diversity of these microorganisms depends on rice cultivars with some genes characterizedas harboring specific groups of microorganisms related to methane ***,there is still aneed for research to determine the balance between methane production and oxidation,as rice plantspossess the ability to regulate net methane *** agronomical practices,such as fertilizerand water management,have been employed to mitigate methane ***,studiescorrelating agronomic and chemical management of methane with productivity are ***,evidences for breeding low-methane-emitting rice varieties are scattered largely due to the absence ofcoordinated breeding *** has indicated that phenotypic characteristics,such as rootbiomass,shoot architecture,and aerenchyma,are highly correlated with methane *** reviewdiscusses available studies that involve the correlation between plant characteristics and *** emphasizes the necessity and importance of breeding low-methane-emitting rice varieties inaddition to existing agronomic,biological,and chemical *** review also delves into the idealphenotypic and physiological characteristics of low-methane-emitting rice and potential breeding techniques,drawing from studies conducted

关键词： methane emission rice breeding aerenchyma greenhouse gas radial oxygen loss

Moving Personal-Cell Network: Characteristics and Performance Evaluation

在线全文

学校读者我要写书评

暂无评论

China Communications 2018年第12期15卷 159-173页

作者： Syed Tariq Shah Minsu Shin Young Min Kwon JaeSheung Shin Ae-soon park Min Young Chung Department of Electrical and Computer Engineering Sungkyunkwan University Department of Telecommunication Engineering FICT Balochistan University of Information Technology Engineering and Management Sciences Mobile Access Research Division Electronics and Telecommunications Research Institute

Recent years have witnessed a huge demand for ubiquitous communications services from continuously moving users. In order to provide seamless network services to high-mobility users, one of the promising solution proposed by 3 GPP is the deployment of moving-relays. In this article, we introduce the concept of Moving-Personal-Cell(mPC), which is a type of moving-relays. mPC is a user-centric network, which aims to provide reliable network services to moving users. A mPC receives data-traffic from eNB and its neighboring mPCs via wireless backhaul and sidehual links respectively and forwards the received data to its serving users. In addition to this, mPC can also increase the network capacity by caching and distributing the popular contents to its serving users. Besides these pros, the mPC also has some limitations, as its performance is highly affected by cross-tier and co-tier interferences. In this article, we analyze the effect of these interferences on mPCs performance. Our results show that the performance of mPC network is equally affected by the capacity of wireless backhaul, sidehaul, and access links. Moreover, since mPCs accommodate data traffic from wireless backhaul, sidehaul links, and content cache, their performance is also affected by the ratio of data-traffic delivered via these links.

关键词： heterogeneous networks moving small cells fixed small cells moving cache network performance evaluation next generation networks

Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第17期16卷 2158-2162页

作者： Hyung soon park Yu Jin Kim Woo Ick Yang Chang Ok Suh Yong Chan Lee Department of Internal Medicine Yonsei University College of Medicine120-752 SeoulSouth Korea Department of Pathology Yonsei University College of Medicine120-752 SeoulSouth Korea Department of Radiation Oncology Yonsei University College of Medicine120-752 SeoulSouth Korea

AIM: To investigate treatment outcome of Helicobacter pylori (*** )-negative low-grade gastric mucosaassociated lymphoid tissue (MALT) ***: In this study,we retrospectively reviewed the clinical outcome and clinicopathologic factors of stage Ⅰ E *** -negative low-grade gastric MALT lymphoma cases from August 1998 to June ***: A total of eleven patients with *** -negative low-grade gastric MALT lymphoma were enrolled in the study and received *** eradication treatment and/or radiotherapy or excisional *** remission (CR) of gastric MALT lymphoma was achieved in all *** time to CR was 1-66 mo (median,1 mo).CONCLUSION: Eradication therapy may be offered as an initial treatment option even in cases of localized *** -negative gastric MALT lymphoma.

关键词： Anti-bacterial agents Helicobacter pylori Mucosa-associated lymphoid tissue lymphoma Radiotherapy Stomach

Exercise and HRT for women well-being

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

山东体育科技 2007年第1期29卷 77-79页

作者： Kye soon park Dept. of PE Ulsan University Korea

How HRT & Exercisc provide the Effect of Women Well - being is discussed here with the Presentation about (1) Information on Hormone & HRT; (9) Introduction to Estrogen Replacemen; (3) Review of Relational Studies.

关键词：体育训练女子体育体育运动体育行为

Rapid Establishment of Tracheal Stenosis in Pigs Using Endotracheal Tube Cuff Overpressure and Electrocautery

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2021年第2期41卷 329-335页

作者： Jin Hyoung Kim Jong Joon Ahn Yangin Jegal Soohyun Bae soon Eun park Moon Sik Jung Ju Ik park Hee Jeong Cha Yongjik Lee Taehoon Lee Division of Respiratory and Critical Care Medicine Department of Intemnal MedicineUlsan University HospitalUniversity of Ulsan College of MedicineUlsan 44033Korea Department of Anesthesiology and Pain Medicine UIsan University HospitalUniversity of Ulsan College of MedicineUlsan 44033Korea Department of Pathology Ulsan University HospitalUniversity of Ulsan College of MedicineUlsan 44033Korea Department of Thoracic and Cardiovascular Surgery Ulsan University HospitalUniversity of Ulsan College of MedicineUlsan 44033Korea

To apply a new airway treatment to humans, preclinical studies in an appropriate animalmodel is needed. Canine, porcine and leporine tracheas have been employed as animal airwaystenosis models using various methods such as chemical caustic agents, laser, and ***, existing models take a long time to develop (3- 8 weeks) and the mechanism of stenosisis different from that in humans. The aim of the present study was to establish a new and fasttracheal stenosis model in pigs using a combination of cuff overpressure intubation (COI) andelectrocautery. Fourteen pigs were divided into three groups: tracheal cautery (TC) group (n=3),COI group (n=3), and COI-TC combination group (n=8). Cuff overpressure (200/400/500 mmHg)was applied using a 9-mm endotracheal tube. Tracheal cautery (40/60 watts) was performed usinga rigid bronchoscopic electrocoagulator. After intervention, the pigs were observed for 3 weeks andbronchoscopy was performed every 7 days. When the cross-sectional area decreased by > 50%, itwas confirmed that tracheal stenosis was established. The time for tracheal stenosis was 14 days inthe TC group and 7 days in the COI-TC combination group. In the COI group, no stenosis *** the COI-TC group, electrocautery (40 watts) immediately after intubation for>1 h with a cufpressure of 200 mmHg or more resulted in suficient tracheal stenosis within 7 days. Moreover, thedegree of tracheal stenosis increased in proportion to the cuff pressure and tracheal intubation *** combined use of cuf overpressure and electrocautery helped to establish tracheal stenosis inpigs rapidly.

关键词： pig tracheal stenosis model cuff overpressure electrocautery