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Oxidative degradation of sunflower oil blended with roasted sesame oil during heating at frying temperature

Grain & Oil Science and Technology 2023年第1期6卷 34-42页

作者： M.Al Amin M.Abbas Ali M.Shamsul Alam Aktarun Nahar sook chin chew Department of Chemistry Rajshahi University of Engineering&TechnologyRajshahi 6204Bangladesh Xiamen University Malaysia CampusBandar SereniaSepang 43900SelangorMalaysia

The efficacy of roasted sesame oil(SO)on the oxidation deterioration of sunflower oil(SFO)during heating was *** concentrations of SO in the SFO were 0,10%,20%,and 30%by *** oxidation profile of oil samples was monitored by evaluating the generation of oxidation products and chemical alterations in the oils'composition during heating at frying temperature(180℃).The results showed that the oxidation parameters(free fatty acid,peroxide value,p-anisidine value,total oxidation status,thiobarbituric acid value,and color index)increased significantly in SFO compared to blends or SO during thermal *** heating,the concentration of polyunsaturated fatty acids(PUFA)was reduced with increased level of saturated fatty acids;these results were observed more in SFO than those of SO or blend ***,the presence of SO in SFO reduced the decomposition of *** Fourier-transform infrared spectroscopy,the peak intensities were significantly altered in SFO compared to the blend oils during *** on the most analytical data,it may be agreed that the heating at frying temperature led to the generation of relatively higher contents of oxidative products in SFO compared to blend oils,showing a lower degree of oxidation occurred in *** best frying performance for the SFO was achieved by using 30%SO extracted from the roasted sesame *** study showed the proper blending of high polyunsaturated oil with SO can produce oil blends with high nutritional values and enhanced stability for daily cooking and deep-frying applications.

关键词： Sesame oil Sunflower oil Fatty acids Oxidative stability Blend oil

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Exosomes as promising frontier approaches in future cancer therapy

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 28-33页

作者： Fatt-Yang chew chin-Hung Tsai Kuang-Hsi Chang Yu-Kang Chang Ruey-Hwang Chou Yi-Jui Liu Department of Medical Imaging China Medical University HospitalTaichung 404TaiwanChina Department of Radiology School of MedicineChina Medical UniversityTaichung 404TaiwanChina Department of Cancer Center Tungs’Taichung MetroHarbor HospitalTaichung 435TaiwanChina Department of Chest Medicine Tungs’Taichung MetroHarbor HospitalTaichung 435TaiwanChina Department of Post-Baccalaureate Medicine College of MedicineNational Chung Hsing UniversityTaichung 402TaiwanChina Department of Medical Research Tungs’Taichung MetroHarbor HospitalTaichung 435TaiwanChina Center for General Education China Medical UniversityTaichung 404TaiwanChina General Education Center Jen-Teh Junior College of MedicineNursing and ManagementMiaoli 356TaiwanChina Department of Nursing Jen-Teh Junior College of MedicineNursing and ManagementMiaoli 356TaiwanChina Graduate Institute of Biomedical Sciences China Medical UniversityTaichung 404TaiwanChina Center for Molecular Medicine China Medical University HospitalTaichung 404TaiwanChina Department of Medical Laboratory and Biotechnology Asia UniversityTaichung 413TaiwanChina Department of Automatic Control Engineering Feng Chia UniversityTaichung 407TaiwanChina

In this editorial,we will discuss the article by Tang et al published in the recent issue of the World Journal of Gastrointestinal *** explored an innovative approach to enhancing gemcitabine(GEM)delivery and efficacy using human bone marrow mesenchymal stem cells(HU-BMSCs)-derived *** manufacture of GEM-loaded HU-BMSCs-derived exosomes(Exo-GEM)has been *** Tang et al’s study demonstrated that Exo-GEM exhibits enhanced cytotoxicity and apoptosis-inducing effects compared to free GEM,highlighting the potential of exosome-based drug delivery systems as a more effective and targeted approach to chemotherapy in pancreatic *** in vivo studies are required to confirm the safety and effectiveness of Exo-GEM before it can be considered for clinical use.

关键词： Mesenchymal stem cells Exosomes Gemcitabine Pancreatic cancer Apoptosis

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Prevalence and genetic divergence of Leptospira interrogans and Leptospira borgpetersenii in house rats(Rattus rattus) from Peninsular Malaysia

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Asian Pacific Journal of Tropical Medicine 2019年第10期12卷 463-471页

作者： Nurul Huda Mohamad Ikbal Subha Bhassu Khanom Simarani Shigehiko Uni chew chin Chan Hasmahzaiti Omar Institute of Biological Sciences Faculty of ScienceUniversity of Malaya50603 Kuala LumpurMalaysia

Objective:To evaluate the prevalence and divergence of genetically identified Leptospira *** the population of Rattus ***:A total of 130 rats were used in this *** infection within the rats were screened using polymerase chain reaction(PCR)-based diagnosis,with Leptospira genusspecific 16 S r RNA primer and pathogenic Leptospira *** Lip L32 primer,on both kidney and liver tissues of Rattus rattus to detect the presence of potential Leptospira ***:Out of 130 rats studied,51(39.23%)individuals were positive for leptospiral *** Local Alignment Search Tool(BLAST)and phylogenetic analysis revealed that both pathogenic Leptospira interrogans and Leptospira borgpetersenii were predominantly ***,both genes disclosed similar clustering patterns of tree topologies between the two *** both genes were conserved,Lip L32 gene portrayed higher nucleotide divergence(5.80%)compared to the 16 S r RNA gene(0.60%).Minimum-spanning network displayed several haplotypes that are unique to each species,suggesting a higher degree of subdivision between both *** for prevalence surveillance,both adult and subadult rats were susceptible to the infection,in which males were the most *** was notable as the favourable organ for colonisation of *** captured from fresh markets were highly infected with Leptospira spp.(54.28%)compared to those from housing areas(26.47%).Conclusions:Rattus rattus represents an important asymptomatic transmitter of pathogenic leptospires,and hence is of public health concerns.

关键词： Pathogenic leptospires Public health PCR Molecular diagnostic Zoonotic

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Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest,but not with aneuploidy and clinicopathological characteristics in gastric cancer

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World Journal of Gastroenterology 2004年第22期10卷 3240-3244页

作者： chew-WunWu chin-WenChi Tze-SingHuang DepartmentofSurgery Taipei-VeteransGeneralHospitalTaipeiTaiwanChina DepartmentofMedicalResearchandEducation Taipei-VeteransGeneralHospitalandInstituteofPharmacologyNationalYang-MingUniversityTaipeiTaiwanChina DivisionofCancerResearch NationalHealthResearchInstitutesTaipeiTaiwanChina

AIM: To study the relevance of spindle assembly checkprotein MAD2 to cellular mitotic status, aneuploidy and other clinicopathological characteristics in gastric cancer. METHODS: Western blot analyses were performed to analyze the protein levels of MAD2 and cyclin B1 in the tumorous and adjacent nontumorous tissues of 34 gastric cancer patients. Cell cycle distribution and DNA ploidy of cancer tissues were also determined by flow cytometry. Conventional statistical methods were adopted to determine the relevance of abnormal MAD2 level to mitotic status, aneuploidy and clinicopathological parameters. RESULTS: Out of 34 gastric cancer patients 25 (74%) exhibited elevated MAD2 levels in their tumorous tissues compared with the corresponding nontumorous tissues. Elevation of MAD2 levels significantly correlated with the increased levels of cyclin B1 expression and G2/M-phase distribution (P=0.038 and P=0.033, respectively), but was not relevant to aneuploidy. The gastric cancer patients with elevated MAD2 levels showed a tendency toward better disease-free and overall survival (P>0.05). However, no association was found between elevated MAD2 levels and patients' clinicopathological characteristics. CONCLUSION: Elevation of MAD2 level is present in 74% of gastric cancer patients, and correlates with increased mitotic checkpoint activity. However, elevation of MAD2 level is not associated with patients' aneuploidy and any of the clinicopathological characteristics.

关键词：纺锤核蛋白 MAD2 细胞分裂有丝分裂非整倍性临床病理学临床特征胃癌肿瘤

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A review on co-pyrolysis of agriculture biomass and disposable medical face mask waste for green fuel production:recent advances and thermo-kinetic models

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Frontiers of Chemical Science and Engineering 2023年第9期17卷 1141-1161页

作者： Melvin X.J.Wee Bridgid L.F.chin Agus Saptoro Chung L.Yiin Jiuan J.chew Jaka Sunarso Suzana Yusup Abhishek Sharma Department of Chemical and Energy Engineering Faculty of Engineering and ScienceCurtin University MalaysiaCDT 250Miri 98009Malaysia Energy and Environment Research Cluster Faculty of Engineering and ScienceCurtin University MalaysiaCDT 250Miri 98009Malaysia Department of Chemical Engineering and Energy Sustainability Faculty of EngineeringUniversiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Institute of Sustainable and Renewable Energy(ISuRE) Universiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Research Centre for Sustainable Technologies Faculty of EngineeringComputing and ScienceSwinburne University of TechnologyKuching 93350Malaysia Generation Unit(Fuel Technology&Combustion) Tenaga Nasional Berhad(TNB)Research Sdn BhdKajang 43000Malaysia Department of Chemical Engineering Manipal University JaipurJaipur 303007India Chemical&Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3000Australia

The Association of Southeast Asian Nations is blessed with agricultural resources,and with the growing population,it will continue to prosper,which follows the abundance of agricultural *** biomass attracted researchers’interest in extracting bio-oil from these ***,the resulting bio-oil has low heating values and undesirable physical ***,co-pyrolysis with plastic or polymer wastes is adopted to improve the yield and quality of the ***,with the spread of the novel coronavirus,the surge of single-use plastic waste such as disposable medical face mask,can potentially set back the previous plastic waste reduction ***,studies of existing technologies and techniques are referred in exploring the potential of disposable medical face mask waste as a candidate for co-pyrolysis with *** parameters,utilisation of catalysts and technologies are key factors in improving and optimising the process to achieve commercial standard of liquid *** copyrolysis involves a series of complex mechanisms,which cannot be explained using simple iso-conversional ***,advanced conversional models are introduced,followed by the evolutionary models and predictive models,which can solve the non-linear catalytic copyrolysis reaction *** outlook and challenges for the topic are discussed in detail.

关键词： biomass COVID-19 wast catalyst pyrolysis kinetics

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Performance of Adaptive MQAM in Cellular System with Nakagami Fading and Log-normal Shadowing

Performance of Adaptive MQAM in Cellular System with Nakagam...

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IEEE第14届国际个人无线移动通信大会

作者： chin Choy CHAI Yong Huat chew Institute for Infocomm Research #02-34/37 TeleTech Park Singapore Science Park II 20 Science Park Road Singapore 117674. Institute for Infocomm Research #02-34/37 TeleTech Park Singapore Science Park II 20 Science Park Road Singapore 117674.

We study the performance of adaptive M-ary Quadrature Amplitude Modulation (MQAM) in wireless cellular system with Nakagami fading and log-normal shadowing. An interference-limited system is assume

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Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts-a possible explanation of the link between smoking and Graves' ophthalmopathy

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International Journal of Ophthalmology(English edition) 2014年第3期7卷 403-407页

作者： Chiaw Ling Chng Oi Fah Lai Charmaine Sze-Min chew Yu Pei Peh Stephanie Man-Chung Fook-Chong Lay Leng Seah Daphne Hsu-chin Khoo Department of Endocrinology Singapore General HospitalLevel 3 the Academia 20 College Road 169856 Singapore Department of Clinical Research Academia Discovery Tower Level 9 Research Office 2 20 College Road 169856Singapore Oculoplastic/Aesthetic Eyeplastic Service Singapore National Eye Centre 11 Third Hospital Avenue 168751Singapore

AIM:To assess the effects of hypoxia on human orbital fibroblasts(OF)on adipogenesis and adipocytokine ***:Human OF were derived from tissues obtained from patients with Graves’ophthalmopathy(GO)and from patients without known thyroid diseases undergoing *** OF were cultured separately under normoxic and hypoxic *** of adipocytokine concentrations using multiplex ELISA and lipid accumulation in the cells using Oil Red O staining were subsequently ***:There was increased adipogenesis in OF from GO subject when exposed to hypoxic culture *** was not observed in OF from normal *** led to an increase in leptin and a decrease in MCP-1 secretion in OF ***:Hypoxia induces adipogenesis in OF and may represent a mechanism by which smoking contributes to deterioration of *** also found novel changes to leptin and MCP-1 production in OF cultures exposed to hypoxia suggesting important roles of these cytokines in the disease process.

关键词： hypoxia smoking Graves' ophthalmopathy

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Helicobacter pylori cagA,iceA and vacA genotypes in patients with gastric cancer in Taiwan

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World Journal of Gastroenterology 2004年第17期10卷 2493-2497页

作者： Hwai-JengLin chin-LinPerng Wen-chingLo chew-WunWu Guan-YingTseng AnnaFen-YauLi I-ChenSun Yueh-HsingOu DivisionofGastroenterology DepartmentofMedicineVGH-TAIPEITaiwanChina I-LanHospital DepartmentofhealthTaiwanChina ZhongxiaoMunicipalHospital TaipeiTaiwanChina DivisionofGeneralSurgery DepartmentofSurgeryVGH-TAIPEITaiwanChina Ton-YenGeneralHospital Hsin-ChnTaiwanChina DepartmentofPathology VGH-TAIPEITaiwanChina InstituteofBiotechnologyinMedicine SchoolofMedicalTechnologyandEngineeringandSchoolofMedicineNationalYang-MingUniversityTaiwanChina

AIM: Helicobacter pylori( H pylori) has been linked to chronic gastritis, peptic ulcer, gastric cancer and *** link of genotypes of Hpylorito gastric cancer remains controversial. The aim of this study was to investigate the Hpylori vacA alleles, cagA and iceA in patients with gastric cancer in ***: Patients with gastric cancer, peptic ulcer and chronic gastritis were enrolled in this study. We obtained biopsy specimens from the stomach at least 2 cm away from the tumor margin in patients with gastric cancer, and from the antrum of stomach in patients with peptic ulcer or chronic gastritis. DNA extraction and polymerase chain reaction were used to detect the presence or absence of cagA and to assess the polymorphism of vacA and ***: A total of 168 patients (gastric ulcer: 77, duodenal ulcer: 66, and chronic gastritis: 25) were found to have positive PCR results of the biopsy specimens from patients with peptic ulcer and chronic gastritis. We found positive cagA (139/168, 83%), m2 (84/168, 50%) and iceA1 (125/168,74%) strains in the majority of patients. In patients with gastric cancer, the vacA sla and slc subtypes were less commonly found than those in non-cancer patients (35/66 vs 127/168, P= 0.0001 for sla and 13/66 vs93/168, P<0.0001 for slc). In the middle region, the mlT strain in patients with gastric cancer was more than that of non-cancer patients(23/66 vs 33/168, P = 0.02).CONCLUSION: In Taiwan, H pylori with positive vacA sla,cagA and iceA1 strains are found in the majority of patients with gastric cancer or non-cancer patients. In patients with gastric cancer, the vacA s1a and slc subtypes are less and m1T is more than in patients with peptic ulcer and chronic gastritis.

关键词：哈比特属幽门菌 cagA1 iceA vacA 基因型胃癌肿瘤消化系统

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Bio-oil production from pyrolysis of oil palm biomass and the upgrading technologies:A review

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Carbon Resources Conversion 2021年第1期4卷 239-250页

作者： Liza Melia Terry Claudia Li Jiuan Jing chew Aqsha Aqsha Bing Shen How Adrian Chun Minh Loy Bridgid Lai Fui chin Deni Shidqi Khaerudini Nishar Hameed Guoqing Guan Jaka Sunarso Research Centre for Sustainable Technologies Faculty of EngineeringComputing and ScienceSwinburne University of TechnologyJalan Simpang Tiga93350 KuchingSarawakMalaysia Department of Bioenergy Engineering and Chemurgy Faculty of Industrial TechnologyInstitut Teknologi BandungBandung 40132Jawa BaratIndonesia Department of Chemical Engineering Monash UniversityVictoria 3800Australia Department of Chemical and Energy Engineering Faculty of Engineering and ScienceCurtin University MalaysiaCDT 25098009 Miri SarawakMalaysia Research Centre for Physics National Research and Innovation Agency(BRIN)Gd.440-442 Kawasan Puspiptek SerpongSouth Tangerang15314 BantenIndonesia Faculty of Science Engineering and TechnologySwinburne University of TechnologyHawthornVictoria 3122Australia Energy Conversion Engineering Group Institute of Regional Innovation(IRI)Hirosaki University2-1-3MatsubaraAomori 030-0813Japan

Oil palm biomass(OPB)represents major portion of the lignocellulosic waste in Malaysia that can be converted into *** review aims to provide important insights in OPB-derived bio-oil production by first discussing the chemical compositions of different OPB and their effects to the bio-oil yield and quality obtained from pyrolysis process,followed by discussing the addition of plastics and catalysts into the pyrolysis for bio-oil upgrading,and lastly summarizing the existing technoeconomic and environmental studies and the potential use of process integration and intensification in this ***(PP),low density polyethylene(LDPE),and high density polyethylene(HDPE)have been commonly used in co-pyrolysis of OPB,which can effectively increase the heating value of bio-oil up to 80%that of ***,acidic,basic,and neutral catalysts have been applied to increase the amount of hydrocarbon and phenol in the bio-oil,further improving the heating value to be comparable to *** bio-oil production from OPB is currently still limited to demonstration scale despite the favorable environmental compatibility and technoeconomic feasibility shown by studies focused on empty fruit bunch(EFB).Several promising advanced pyrolysis processes that integrate other processes such as anaerobic digestion,hydrogen production process,and heat and power generation units as well as the advanced reactor designs are also overviewed here as future innovation of the bio-oil production from OPB,which may play more significant role as the technology matures.

关键词： Bio-oil production Co-pyrolysis Oil palm biomass Plastic waste Pyrolysis

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Associations of lifestyle and diet with the risk of nasopharyngeal carcinoma in Singapore:a case–control study

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chinese Journal of Cancer 2017年第2期36卷 63-70页

作者： sook Kwin Yong Tam Cam Ha Ming Chert Richard Yeo Valerie Gaborieau James D.McKay Joseph Wee Division of Clinical Trials and Epidemiological Sciences National Cancer Centre Singapore11 Hospital DriveSingapore 169610Singapore Medical Education Research&Evaluation Department(MERE)Duke-NUS Medical School8 College RoadSingapore 169857Singapore Division of Radiation Oncology National Cancer Centre Singapore11 Hospital DriveSinga-pore 169610Singapore Genetic Cancer Susceptibility Group International Agency for Research on CancerWorld Health Organization150 Cours Albert Thomas69372 Lyon Cedex 08France

Background: Nasopharyngeal carcinoma(NPC) is a commonly diagnosed cancer in Southeast Asia. Many studies have examined the risk factors for NPC, yet the roles of some risk factors remain inconclusive. The purpose of this study was to examine associations between modifiable lifestyle factors and the risk of NPC in the Singaporean ***: We conducted a case–control study in Singapore with 300 patients and 310 controls who were recruited between 2008 and 2012. Each control was selected and individually matched to each patient based on sex, ethnicity, and age(±5 years). A total of 290 pairs of cases and controls were matched successfully. We examined lifestyle factors such as tobacco smoking, alcohol drinking, various salted and preserved food consumption, and weaning ***: After adjusting for covariates, multivariate analysis showed that those participants who were current smokers and had ever smoked tobacco had a higher risk of NPC than participants who had never smoked, with odds ratios(ORs) of 4.50(95% confidence interval [CI] 2.58–7.86; P < 0.001) and 2.52(95% CI 1.54–4.12; P < 0.001), respectively. Those who consumed salted vegetables at least once a week also showed a significantly increased risk of NPC than those who never or rarely consumed salted vegetables, with an OR of 4.18(95% CI 1.69–10.38; P = 0.002).Conclusion: Smoking(currently and ever-smoked) and consuming salted vegetables once a week or more were lifestyle risk factors for NPC, and changes of these factors for the better may reduce the risk of NPC.

关键词： Nasopharyngeal carcinoma Diet Smoking Alcohol drinking Case–control study Preserved food

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