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Anonymous TollPass: A Blockchain-Based Privacy-Preserving Electronic Toll Payment Model

Computers, Materials & Continua 2024年第6期79卷 3495-3518页

作者： Jane kim soojin Lee Chan Yeob Yeun Seung-Hyun Seo Department of Electronic&Electrical Engineering Graduate SchoolHanyang UniversitySeoul04763Korea Department of Electrical Engineering and Computer Science Khalifa University of Science and TechnologyAbu Dhabi127788United Arab Emirates School of Electrical Engineering Hanyang UniversityERICAAnsan15588Korea

As big data,Artificial Intelligence,and Vehicle-to-Everything(V2X)communication have advanced,Intelligent Transportation Systems(ITS)are being developed to enable efficient and safe transportation systems.Electronic Toll Collection(ETC),which is one of the services included in ITS systems,is an automated system that allows vehicles to pass through toll plazas without stopping for manual payment.The ETC system is widely deployed on highways due to its contribution to stabilizing the overall traffic system flow.To ensure secure and efficient toll payments,designing a distributed model for sharing toll payment information among untrusted toll service providers is necessary.However,the current ETC system operates under a centralized model.Additionally,both toll service providers and toll plazas know the toll usage history of vehicles.It raises concerns about revealing the entire driving routes and patterns of vehicles.To address these issues,blockchain technology,suitable for secure data management and data sharing in distributed systems,is being applied to the ETC system.Blockchain enables efficient and transparent management of ETC information.Nevertheless,the public nature of blockchain poses a challenge where users’usage records are exposed to all participants.To tackle this,we propose a blockchain-based toll ticket model named AnonymousTollPass that considers the privacy of vehicles.The proposed model utilizes traceable ring signatures to provide unlinkability between tickets used by a vehicle and prevent the identity of the vehicle using the ticket from being identified among the ring members for the ticket.Furthermore,malicious vehicles’identities can be traced when they attempt to reuse tickets.By conducting simulations,we show the effectiveness of the proposed model and demonstrate that gas fees required for executing the proposed smart contracts are only 10%(when the ring size is 50)of the fees required in previous studies.

关键词： Blockchain electronic toll collection smart contract traceable ring signature

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Three-dimensional kagome structures in a PCL/HA-based hydrogel scaffold to lead slow BMP-2 release for effective bone regeneration

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Bio-Design and Manufacturing 2023年第1期6卷 12-25页

作者： Se-Hwan Lee Kang-Gon Lee Jaeyeon Lee Yong Sang Cho Min-Soo Ghim soojin kim Su-Jin Heo Yongdoo Park Young-Sam Cho Bu-Kyu Lee McKay Orthopaedic Research Laboratory Department of Orthopaedic SurgeryPerelman School of MedicineUniversity of Pennsylvania36th Street and Hamilton WalkPhiladelphiaPA 19104USA Department of Biomedical Sciences College of MedicineKorea University73Goryeodae-roSeongbuk-guSeoul 02841Republic of Korea Medical Device Development Center Daegu-Gyeongbuk Medical Innovation Foundation(K-MEDI hub)80Cheombok-roDong-guDaegu 41061Republic of Korea Department of Mechanical Engineering College of EngineeringWonkwang University460Iksan-daeroIksan 54538Republic of Korea Biomedical Engineering Research Center Asan Institute for Life SciencesAsan Medical Center88Olympic-roSongpa-guSeoul 05505Republic of Korea Department of Mechanical Design Engineering College of EngineeringWonkwang University460Iksan-daeroIksan 54538Republic of Korea MECHABIO Group Wonkwang University460Iksan-daeroIksan 54538Republic of Korea Department of Oral and Maxillofacial Surgery Asan Institute for Life SciencesAsan Medical Center88Olympic-roSongpa-guSeoul 05505Republic of Korea

Osteoconductive function is remarkably low in bone disease in the absence of bone tissue surrounding the grafting site,or if the bone tissue is in poor condition.Thus,an effective bone graft in terms of both osteoconductivity and osteoinductivity is required for clinical therapy.Recently,the three-dimensional(3D)kagome structure has been shown to be advantageous for bone tissue regeneration due to its mechanical properties.In this study,a polycaprolactone(PCL)kagome-structure scaffold containing a hyaluronic acid(HA)-based hydrogel was fabricated using a 3D printing technique.The retention capacity of the hydrogel in the scaffold was assessed in vivo with a rat calvaria subcutaneous model for 3 weeks,and the results were compared with those obtained with conventional 3D-printed PCL grid-structure scaffolds containing HA-based hydrogel and bulk-type HA-based hydrogel.The retained hydrogel in the kagome-structure scaffold was further evaluated by in vivo imaging system analysis.To further reinforce the osteoinductivity of the kagome-structure scaffold,a PCL kagome-structure scaffold with bone morphogenetic protein-2(BMP-2)containing HA hydrogel was fabricated and implanted in a calvarial defect model of rabbits for 16 weeks.The bone regeneration characteristics were evaluated with hematoxylin and eosin(H&E),Masson’s trichrome staining,and micro-CT image analysis.

关键词： Kagome-structure scaffold Retention capacity Biomimetic hydrogel Bone morphogenetic protein-2(BMP-2)

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Effects of dietary supplementation of bacteriophage cocktail on health status of weanling pigs in a non-sanitary environment

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Journal of Animal Science and Biotechnology 2023年第4期14卷 1661-1677页

作者： YoHan Choi Abdolreza Hosseindoust Sang Hun Ha Joeun kim YeJin Min YongDae Jeong JunYoung Mun soojin Sa JinSoo kim Swine Science Division National Institute of Animal ScienceRural Development AdministrationCheonan 31000Republic of Korea Department of Animal Industry Convergence Kangwon National UniversityChuncheon 24341Republic of Korea

Background The study evaluated the effects of bacteriophage cocktail(BP)and ZnO administered during weaning time for piglets exposed to a non-sanitary environment.The bacteriophages were designed to eliminate Escherichia coli(K88,K99 and F41),Salmonella(typhimurium and enteritidis),and Clostridium perfreingens(types A and C).Forty 21-day-old crossbreed piglets were assigned to four treatments,including the PC(sanitary environment),NC(nonsanitary environment),BP(NC plus 108 pfu/kg BP),and ZO(NC plus 2,500 mg/kg ZnO).Piglets in the NC,BP and ZO were kept in a non-sanitary environment for 14 d,which was contaminated with the feces of infected pigs.Results Pigs in the BP and ZO treatments had a higher final body weight compared with the NC.The NC treatment showed the highest concentration of inflammatory cytokines including interleukin(IL)-1β,IL-6 and tumor necrosis factor-αin the plasma.The administration of BP and ZO showed lower myeloperoxidase concentrations compared with the NC.The NC treatment showed a lower concentration of superoxide dismutase in serum compared with the PC.Among the treatments in non-sanitary environment,the NC treatment showed a higher concentration of malondialdehyde compared with the ZO.The PC treatment showed a lower concentration of butyric acid in the feces compared with the BP treatment.Among non-sanitary treatments,the villus height in the duodenum was greater in the BP and ZO compared with the NC.The lower abundance of Proteobacteria phylum was observed in the BP and PC treatments compared with the NC.The highest relative abundance of Eubacterium was recorded in the BP treatment.The abundance of Megasphaera and Schwartzia was higher in the NC pigs compared with the BP piglets.The abundance of Desulfovibrio was lower in the supplemented treatments(BP and ZO)compared with non-supplemented(NC and PC).The abundance of Cellulosilyticum genera was higher in the BP and ZO treatments rather than in the NC.The piglets in the NC treatment had the highest abundance of Escherichia-Shigella,follo

关键词： Antioxidant Cytokines Diarrhea Fecal score Inflammation Microbiota Proteobacteria

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Sperm hyaluronidase is critical to mammals'fertilization for its ability to disperse cumulus-oocyte complex layer

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Asian Journal of Andrology 2022年第4期24卷 411-415页

作者： Dong-Won Seol Sang Hoon Joo Young-Hyun kim Bong-Seok Song Bo-Woong Sim Sun-Uk kim soojin Park Gabbine Wee Ekyune kim Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF)Daegu 41061Korea College of Pharmacy Catholic University of DaeguGyeongbuk 38430Korea National Primate Research Center(NPCR) Korea Research Institute of Bioscience and BiotechnologyChungcheongbuk-do 28116Korea Futuristic Animal Resource and Research Center Korea Research Institute of Bioscience and BiotechnologyChungcheongbuk-do 28116Korea Department of Biochemistry and Molecular Biology Melvin and Bren Simon Comprehensive Cancer CenterIndiana University School of MedicineIndianapolisIN 46202USA

Glycosylphosphatidylinositol-anchored sperm hyaluronidases have long been believed to assist in sperm penetration through the cumulus-oocyte complex(COC);however,their role in mammalian fertilization remains unclear.Previously,we have shown that hyaluronidase 5(Hyal5)/Hyal7 double-knockout(dKO)mice produce significantly fewer offspring than their wild-type(WT)counterparts because of defective COC dispersal.Male infertility is mainly caused by a low sperm count.It can be further exacerbated by the deficiency of sperm hyaluronidase,which disperses the cumulus cells of the outer layer of the COC.In the current study,we evaluated the effects of a low count of Hyal-deficient sperm and conditions of ovulated oocytes on the fertilization rate using a mouse model.Our results demonstrated that a low sperm count further decreases the in vitro fertilization(IVF)rate of Hyal-deficient dKO spermatozoa.In addition,the dKO spermatozoa resulted in a fertilization rate of 12.5%upon fertilizing COCs with a thick cumulus layer,whereas the IVF rate was comparable to that of WT spermatozoa when oocytes with a thin or no cumulus layer were fertilized.Finally,we proved that the IVF rate of dKO spermatozoa could be recovered by adding rat spermatozoa as a source of sperm hyal.Our results suggest that a deficiency of proteins involved in fertilization,such as sperm hyal,has a vital role in fertilization.

关键词： HYAL5 HYAL7 cumulus-oocyte complex fertilization infertility sperm hyaluronidase

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Efficient Remote Identification for Drone Swarms

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Computers, Materials & Continua 2023年第9期76卷 2937-2958页

作者： Kang-Moon Seo Jane kim soojin Lee Jun-WooKwon Seung-Hyun Seo The Department of Electronic&Electrical Engineering Graduate SchoolHanyang UniversityAnsanKorea School of Electrical Engineering Hanyang University ERICAAnsanKorea

With the advancement of unmanned aerial vehicle(UAV)technology,the market for drones and the cooperation of many drones are expanding.Drone swarms move together in multiple regions to perform their tasks.A Ground Control Server(GCS)located in each region identifies drone swarmmembers to prevent unauthorized drones from trespassing.Studies on drone identification have been actively conducted,but existing studies did not consider multiple drone identification environments.Thus,developing a secure and effective identification mechanism for drone swarms is necessary.We suggested a novel approach for the remote identification of drone swarms.For an efficient identification process between the drone swarm and the GCS,each Reader drone in the region collects the identification information of the drone swarmand submits it to the GCS for verification.The proposed identification protocol reduces the verification time for a drone swarm by utilizing batch verification to verify numerous drones in a drone swarmsimultaneously.To prove the security and correctness of the proposed protocol,we conducted a formal security verification using ProVerif,an automatic cryptographic protocol verifier.We also implemented a non-flying drone swarmprototype usingmultiple Raspberry Pis to evaluate the proposed protocol’s computational overhead and effectiveness.We showed simulation results regarding various drone simulation scenarios.

关键词： Drone remote identification drone swarms multi-drone authentication

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AF1q inhibited T cell attachment to breast cancer cell by attenuating Intracellular Adhesion Molecule-1 expression

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Journal of Cancer Metastasis and Treatment 2019年第3期4卷 20-31页

作者： Jino Park Jae Yeon Hwang Alexandra Thore soojin kim Tomiteru Togano Shotaro Hagiwara Juw Won Park William Tse James Graham Brown Cancer Center University of Louisville School of MedicineLouisvilleKY 40202USA Division of Blood and Bone Marrow Transplantation Department of MedicineUniversity of Louisville School of MedicineLouisvilleKY 40202USA Department of Computer Science and Computer Engineering University of LouisvilleLouisvilleKY 40292USA Division of Haematology National Center for Global Health and MedicineTokyo 162-8655Japan Division of Haematology Tokyo Women’s Medical UniversityTokyo 162-8666Japan

Aim: To investigate whether AF1q, overexpressed in metastatic cells compared with the primary tumor cells, plays a pivotal role in breast cancer metastasis. Methods: To investigate whether AF1q has a responsibility in the acquisition of a metastatic phenotype, we performed RNA-sequencing (RNA-Seq) to identify the gene signature and applied the Metacore direct interactions network building algorithm with the top 40 amplicons of RNA-Seq. Results: Most genes were directly linked with intercellular adhesion molecule-1 (ICAM-1). Likewise, we identified that ICAM-1 expression is attenuated in metastatic cells compared to primary tumor cells. Moreover, overexpression of AF1q attenuated ICAM-1 expression, whereas suppression of AF1q elicited the opposite effect. AF1q had an effect on ICAM-1 promoter region and regulated its transcription. Decreased ICAM-1 expression ;affected the attachment of T cells to a breast cancer cell monolayer. We confirmed the finding by performing the analysis on Burkitt's lymphoma. Conclusion: Attenuation of ICAM-1 by AF1q on tumor cells disadvantages host anti-tumor defenses through the trafficking of lymphocytes, which affects tumor progression and metastasis.

关键词： MLLT11 AF1q intercellular adhesion molecule-1 breast cancer metastasis RNA-sequencing

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Factors Affecting the Genetic Diagnostic Rate in Congenital Heart Disease

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Congenital Heart Disease 2022年第6期17卷 653-673页

作者： Jun Sung Park Go Hun Seo Yunha Choi soojin Hwang Minji Kang Hyo-Sang Do Young-Hwue kim Jeong Jin Yu Ellen Ai-Rhan kim Euiseok Jung Byong Sop Lee Jae Suk Baek Beom Hee Lee Department of Pediatrics Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea 3 Billion Inc.SeoulKorea Genome Research Center for Birth Defects and Genetic Diseases Asan Institute for Life SciencesAsan Medical CenterSeoulKorea Division of Cardiology Department of PediatricsAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Division of Neonatology Department of PediatricsAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Medical Genetics Center Asan Medical Center Children’s HospitalUniversity of Ulsan College of MedicineSeoulKorea

Background: Over 400 genes contribute to the development of congenital heart disease (CHD). Additionally,multisystemic manifestations accompanying syndromic CHD pose a higher risk of genetic diseases. This studyinvestigated the diagnostic yield of whole-exome sequencing (WES) in patients with sporadic syndromic CHDand the phenotypic factors affecting the genetic diagnostic rate. Methods: Sixty-four patients with sporadic syndromicCHD aged 0.05), betweenthe groups with and without a diagnostic variant. However, patients with ≥3 extracardiac phenotypes had a significantlyhigher likelihood of having a diagnostic variant than those with ≤2 (38.3% vs. 5.9%, odds ratio = 9.93,95% confidence interval = 1.21–81.44, P = 0.013). Conclusions: The number of extracardiac phenotypes is importantin predicting the possibility of genetic diagnosis. Physicians will be able to select patients with a high probabilityof genetic diagnosis and provide appropriate genetic counseling based on the results of this study.

关键词： Heart defects congenital whole-exome sequencing genetic testing phenotype

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学术情境下社会科学研究者的个人信息管理

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图书情报知识 2017年第6期34卷 12-23页

作者： soojin Park Kyung-Sun kim 占南韩国亚洲文化中心美国威斯康辛大学麦迪逊分校河南科技大学管理学院

随着个人需要处理的信息不断增加，有效地管理信息显得至关重要。当前的研究虽然揭示了个人信息集管理策略，但是主要局限在工作场所或特殊应用中，而且重点主要关注个人信息集管理结果，而不是管理过程中的特殊活动。因此需要更多的研... 详细信息

随着个人需要处理的信息不断增加，有效地管理信息显得至关重要。当前的研究虽然揭示了个人信息集管理策略，但是主要局限在工作场所或特殊应用中，而且重点主要关注个人信息集管理结果，而不是管理过程中的特殊活动。因此需要更多的研究调查个人信息集管理是如何实施进行的，既要关注过程也要关注结果。

关键词：个人信息管理科学研究者社会情境学术信息集个人需要管理信息

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以丝网印刷方式印刷电子监管标签的研究

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中国印刷与包装研究 2009年第3期1卷 72-74页

作者： Namsoo Lim Jaeyoung kim soojin Lee Namyoung kim Gyoujin Cho 陈虹 the School of Applied Materials Sunchon National University the Paru RFID Research Institute Sunchon National University the Department of Electrical Engineering Kwangwoon University

在塑料薄膜上采用丝网印刷方式印刷谐振标签,已经成为低成本电子监管标签的生产方式。以印刷方式生产的谐振标签,可以方便地在印刷过程中通过改变感应器和电容器的印刷长度和尺寸来改变谐振标签的谐振频率。谐振标签的质量因子(Q)主要... 详细信息

在塑料薄膜上采用丝网印刷方式印刷谐振标签,已经成为低成本电子监管标签的生产方式。以印刷方式生产的谐振标签,可以方便地在印刷过程中通过改变感应器和电容器的印刷长度和尺寸来改变谐振标签的谐振频率。谐振标签的质量因子(Q)主要取决于印刷感应器的薄膜阻抗,印刷方式生产的谐振标签能够获得的最大Q值约为45。由于这种谐振标签能够用卷筒进料的塑料薄膜进行印刷,因此,各种谐振频率的电子标签都能够通过这种印刷方式进行大批量低成本生产。

关键词： EAS标签印刷型电子产品谐振电路丝网印刷

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财政分权与政府公信力关系:韩国案例分析

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国际行政科学评论（中文版） 2022年第2期 102-121页

作者：金秀珍李允秀金泰熙戴一鸣(译) 王秋蕾(审校) 新加坡南洋理工大学社会科学学院中国山东大学政治学与公共管理学院韩国国立首尔科技大学公共管理系中国人事科学研究院公务员管理研究室不详

今天,为了更好地响应本地居民的多样化需求,更有效地维护公共利益,很多发展中国家继续实施财政分权制度。然而,人们对财政分权与政府公信力之间的联系仍然知之甚少。本文以韩国为案例开展实证研究,分析财政分权制度如何提高政府公信力... 详细信息

今天,为了更好地响应本地居民的多样化需求,更有效地维护公共利益,很多发展中国家继续实施财政分权制度。然而,人们对财政分权与政府公信力之间的联系仍然知之甚少。本文以韩国为案例开展实证研究,分析财政分权制度如何提高政府公信力——不仅包括国家层面,还包括地方层面。本文进行了多水平回归和面板数据分析,研究成果部分证实了赞成财政分权的研究的结论,即地方财政自主权的增长与政府公信力呈显著正相关。具体而言,我们发现随着财政分权制度的完善,公众对地方政府的信任度也相应提高。此外,我们的研究还发现,在提升政府公信力方面,收入分权的效果往往比支出分权更加明显。这个结果表明,从长远来看,比起赋予其支出自主权,允许地方政府拥有自己的收入来源,能够帮助地方政府更好地响应公众需求。

关键词：支出分权财政分权地方财政自治地方公信力政府公信力

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