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Curative resection of leiomyosarcoma of the descending colon with metachronous liver metastasis: A case report

World Journal of Gastrointestinal Surgery 2023年第5期15卷 992-999页

作者： soo-hyeon lee Sang-Ho Bae Sang-Cheol lee Tae-Sung Ahn Zisun Kim Hae-Il Jung Department of Surgery Soonchunhyang University Cheonan HospitalCheonan 31151ChungnamSouth Korea Department of Internal Medicine Soonchunhyang University Cheonan HospitalCheonan 31151ChungnamSouth Korea Department of Surgery Soonchunhyang University Bucheon HospitalBucheon 14584GyeonggiSouth Korea

BACKGROUND Leiomyosarcoma(LMS)has a poor prognosis and rarely originates from the *** resection is possible,surgery is the first treatment most commonly ***,no standard treatment exists for hepatic metastasis of LMS;although,several treatments,such as chemotherapy,radiotherapy,and surgery,have been ***,the management of liver metastases remains *** SUMMARY We present a rare case of metachronous liver metastasis in a patient with LMS originating from the descending colon.A 38-year-old man initially reported abdominal pain and diarrhea over the previous two *** revealed a 4-cm diameter mass in the descending colon,40 cm from the anal *** tomography revealed intussusception of the descending colon due to the 4-cm *** patient underwent a left *** analysis of the tumor revealed that it was positive for smooth muscle actin and desmin,and negative for cluster of differentiation 34(CD34),CD117,and discovered on gastrointestinal stromal tumor(GIST)-1,which are characteristic of gastrointestinal LMS.A single liver metastasis developed 11 mo postoperatively;the patient subsequently underwent curative resection *** patient remained disease-free after six cycles of adjuvant chemotherapy(doxorubicin and ifosfamide),and 40 and 52 mo after liver resection and primary surgery,*** cases were obtained from a search of Embase,PubMed,MEDLINE,and Google *** Early diagnosis and surgical resection may be the only potential curative options for liver metastasis of gastrointestinal LMS.

关键词： Leiomyosarcoma Colon Liver metastasis Surgical resection Treatment Case report

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Unveiling anomalous lattice shrinkage induced by Pi-backbonding in Prussian blue analogues

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Journal of Energy Chemistry 2022年第7期31卷 121-128,I0004页

作者： Ju-hyeon lee Jin-Gyu Bae hyeon Jeong lee Ji Hoon lee School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Department of Materials University of OxfordOxford OX13PHUnited Kingdom

Transition-metal(TM)-based Prussian blue and its analogues(TM-PBAs) have attracted considerable attention as cathode materials owing to their versatile ion storage capability with tunable working voltages. TM-PBAs with different crystal structures, morphologies, and TM combinations can exhibit excellent electrochemical properties because of their unique and robust host frameworks with well-defined ionic diffusion channels. Nonetheless, there is still a lack of understanding regarding the performance dependence of TM-PBAs on structural changes during charging/discharging processes. In this study, in situ X-ray diffraction and X-ray absorption fine structure analyses elucidate the TMdependent structural changes in a series of TM-PBAs during the charging and discharging *** the discharging process, the lattice volume of Fe-PBA increased while those of Ni-and Cu-PBAs decreased. This discrepancy is attributed to the extent of size reduction of the cyanometallate complex([Fe(CN)_(6)]) via pi-backbonding from Fe to C due to redox flips of the low-spin Fe^(3+/2+) ion. This study presents a comprehensive understanding of how TM selection affects capacity acquisition and phase transition in TM-PBAs, a promising class of cathode materials.

关键词： Prussian blue analogues X-ray diffraction X-ray absorption fine structure Pi-backdonation Cyanides

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Development of benthic macroinvertebrates sediment index(BSI) for bioassessment of freshwater sediment

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International Journal of Sediment Research 2019年第4期34卷 368-378页

作者： Pil Jae Kim Jong hyeon lee In Ae Huh Dong soo Kong Department of Life Science Kyonggi University Environmental Health & Safety Research Institute EH R&C CO.Ltd. Water Environmental Engineering Research Division National Institute of Environmental Research

Sediment quality has been evaluated in a variety of ways since the early 1990 s in studies from Europe. In South Korea, most studies have used an indicator value for benthic macroinvertebrates based on water quality, not sediment quality. To date, few studies have examined the biological integrity of benthic macroinvertebrate communities in South Korea. In the current study, the tolerance valency and value in samples and the indicator weight values were measured for 43 benthic macroinvertebrate taxa from 73 sampling units in South Korea from 2014 to 2016. Total organic carbon, the amount of heavy metals, and total ammonia nitrogen were analyzed. The average grade for each pollutant was used as the sediment quality index. A benthic macroinvertebrates sediment index was developed for bioassessment of freshwater sediment. The benthic macroinvertebrates sediment index, which is based on the relative frequency of occurrence of macroinvertebrates, was highly correlated with pollution levels in the sediment. This index can be used in the field to assess the contamination of freshwater sediment. As the sample size was small in the current study and there were taxonomic limitations of Chironomidae larvae,further research is needed to improve the reliability of the benthic macroinvertebrates sediment index.

关键词： Benthic macroinvertebrates Bioassessment Freshwater sediment Sediment quality index

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Multi-channel electromyography pattern classification using deep belief networks for enhanced user experience

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Journal of Central South University 2015年第5期22卷 1801-1808页

作者： SHIM hyeon-min lee Sangmin Institute for Information and Electronic Research Inha University 100 Inharo Incheon 402-751 Korea Department of Electronic Engineering Inha University 100 Inharo Incheon 402-751 Korea

An enhanced algorithm is proposed to recognize multi-channel electromyography(EMG) patterns using deep belief networks(DBNs). It is difficult to classify the EMG features because an EMG signal has nonlinear and time-varying ***, in several previous studies, various machine-learning methods have been applied. A DBN is a fast, greedy learning algorithm that can find a fairly good set of weights rapidly, even in deep networks with a large number of parameters and many hidden layers. To evaluate this model, we acquired EMG signals, extracted their features, and then compared the model with the DBN and other conventional classifiers. The accuracy of the DBN is higher than that of the other algorithms. The classification performance of the DBN model designed is approximately 88.60%. It is 7.55%(p=9.82×10-12) higher than linear discriminant analysis(LDA) and 2.89%(p=1.94×10-5) higher than support vector machine(SVM). Further, the DBN is better than shallow learning algorithms or back propagation(BP), and this model is effective for an EMG-based user-interfaced system.

关键词： electromyography(EMG) pattern classification feature extraction deep learning deep belief network(DBN)

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Fabrication of high-strength duplex nanoporous Cu by dealloying a dual-phase Mg-Cu precursor alloy

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Journal of Magnesium and Alloys 2020年第3期8卷 910-916页

作者： Si-Young lee soo-Min Baek Eun-Ji Gwak Na-Ri Kang Ju-Young Kim Su-hyeon Kim Jung Gu lee Sung soo Park School of Materials Science and Engineering Ulsan National Institute of Science and TechnologyUlsan 44919Republic of Korea Korea Institute of Materials Science Changwon 51508Republic of Korea School of Materials Science and Engineering University of UlsanUlsan 44610Republic of Korea

Duplex nanoporous Cu was successfully fabricated by dealloying a dual-phase Mg-Cu precursor alloy consisting of intermetallic Mg2Cu and *** duplex nanoporous Cu with embedded nanoporous struts exhibited highly enhanced strength compared to the typical monolithic nanoporous Cu under both compressive and flexural test conditions at room temperature;the duplex np-Cu sample exhibited a 12 times higher compressive strength and a 40 times greater flexural strength than the monolithic np-Cu *** responsible for the strength enhancement in the duplex nanoporous Cu are discussed.

关键词： Mg-Cu alloy Nanoporous Cu Dealloying Duplex structure Strength

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Velocity Profiles between Two Baffles in a Shell and Tube Heat Exchanger

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Journal of Thermal Science 2015年第4期24卷 356-363页

作者： Tae-Hyun Chang Chang-Hoan lee Hae-soo lee Kwon-soo lee Senior Research Fellow of RESEAT Korea Institute of Science and Technology Information Korea Institute of Science and Technology Information Postdoctoral Research Fellow School of Mechanical Engineering of Kyungnam University International University of Korea

Heat exchangers are extensively utilized for waste heat recovery,oil refining,chemical processing,and steam *** this study,velocity profiles are measured using a 3D particle image velocimetry(PIV)system between two baffles in a shell and tube heat exchanger for parallel and counter *** PIV and computational fluid dynamics results show the occurrence of some strong vectors near the *** vectors are assumed due to the clearance between the inner tubes and the front ***,the major parts of the vectors are moved out through the bottom opening of the rear baffle,and other vectors produce a large circle between the two *** simulations are conducted to investigate the effects of the baffle on the heat exchanger using the Fluent *** k-εturbulence model is employed to calculate the flows along the heat exchanger.

关键词： Baffle P1V Shell and tube heat exchanger Cut off ratio CFD

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Vaporization reduction characteristics of aqueous ammonia solutions by the addition of ethylene glycol, glycerol and glycine to the CO_2 absorption process

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Journal of Environmental Sciences 2012年第3期24卷 494-498页

作者： Jong-Beom Seo soo-Bin Jeon Je-Young Kim Gang-Woo lee Jong-hyeon Jung Kwang-Joong Oh Department of Environmental Engineering Pusan National University Busan 609735 Korea. Research Institute of Industrial Science & Technology Pohang 790330 Korea Research & Development Institute of Yoosung Co. Ltd. Ulsan 680070 Korea Faculty of Health Science Daegu Haany University Daegu 712715 Korea

Aqueous ammonia （NH3） solution can be used as an alternative absorption for the control of CO2 emitted from flue gases due to its high absorption capacity, fast absorption rate and low corrosion problem. The emission of CO2 from iron and steel plants requires much attention, as they are higher than those emitted from power plants at a single point source. In the present work, low concentration ammonia liquor, 9 wt.%, was used with various additives to obtain the kinetic properties using the blast furnace gas model. Although a solution with a high ammonia concentration enables high CO2 absorption efficiency, ammonium ions are lost as ammonia vapor, resulting in reduced CO2 absorption due to the lower concentration of the ammonia absorbent. To decrease the vaporization of ammonia, ethylene glycol, glycerol and glycine, which contain more than one hydroxyl radical, were chosen. The experiments were conducted at 313 K similar to the CO2 absorption conditions for the blast furnace gas model.

关键词： ammonia vaporization blast furnace gas ethylene glycol glycerol glycine

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Silent advanced large cell neuroendocrine carcinoma with synchronous adenocarcinoma of the colon:A case report

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World Journal of Gastrointestinal Oncology 2022年第11期14卷 2266-2272页

作者： hyeon Seok Baek Sang Wook Kim soo Teik lee Ho Sung Park Seung Young Seo Department of Internal Medicine Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University HospitalJeonju-si 56445Jeollabuk-doSouth Korea Department of Pathology Jeonbuk National University Medical SchoolJeonjusi 56445Jeollabuk-doSouth Korea

BACKGROUND Large cell neuroendocrine carcinoma(LCNEC)accounts for about 0.25%of colorectal cancer ***,synchronous LCNEC and adenocarcinoma coexistence in the colon is very *** are usually aggressive and have a poor ***,colorectal LCNEC patients complain of abdominal symptoms such as pain,diarrhea or hematochezia because it is often diagnosed as an advanced disease that accompanies metastatic *** SUMMARY We describe a case of relatively asymptomatic synchronous LCNEC and colon adenocarcinoma.A 62-year-old male patient visited our hospital due to anemia detected by a local health *** did not complain of melena,hematochezia or abdominal *** examination was unremarkable and his abdomen was soft,nontender and nondistended with no palpable *** tests revealed anemia with hemoglobin 5.1 g/*** revealed an ulcerofungating lesion in the ascending colon and about a 1.5 cm-sized large sessile polyp in the sigmoid *** biopsy of the ascending colon lesion revealed the ulcerofungating mass that was LCNEC and endoscopic mucosal resection at the sigmoid colon lesion showed a large polypoid lesion that was *** liver,lung,bone and lymph nodes metastasis was found on chest/abdominal computed tomography and positron emission *** patient was diagnosed with advanced colorectal LCNEC with liver,lung,bone and lymph node metastasis(stage IV)and synchronous colonic adenocarcinoma *** this case,no specific symptom except anemia was observed despite the multiple *** patient refused systemic chemotherapy and was discharged after *** We report a case of silent LCNEC of the colon despite the advanced state and synchronous adenocarcinoma.

关键词： Large cell neuroendocrine carcinoma Colon Synchronous Adenocarcinoma Case report

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PGLYRP1 protein as a novel mediator of cellular dialogue in neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 1993-1994页

作者： Anup Bhusal Won-Ha lee Kyoungho Suk Department of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea BK21 Plus KNU Biomedical Convergence Program Department of Biomedical ScienceSchool of MedicineKyungpook National UniversityDaeguRepublic of Korea School of Life Sciences BK21 plus KNU Creative BioResearch GroupKyungpook National UniversityDaeguRepublic of Korea Brain Science and Engineering Institute Kyungpook National UniversityDaeguRepublic of Korea

Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.

关键词： inflammation considerably

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong lee Su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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