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Pancreatic parenchymal injection of ethanol and octreotide to induce focal pancreatic fibrosis in rats: Strategies to eliminate postoperative pancreatic fistula

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Hepatobiliary & Pancreatic Diseases International 2018年第1期17卷 81-85页

作者： soo ho lee Tae ho hong Department of Surgery Uijeongbu St.Mary’s Hospital College of Medicine The Catholic University of Korea Department of Surgery Seoul St.Mary’s Hospital College of Medicine The Catholic University of Korea

Background: Postoperative pancreatic fistula(POPF) is more likely to occur in a soft pancreas compared to a hard pancreas in which fibrosis has progressed. There is almost no leakage at the anastomosis site or cut surface of a hard pancreas. The aim of this study was to induce localized fibrosis at the cut surface of the pancreas in a rat ***: Thirty-six rats were divided into three groups(group S: normal saline group; group E: ethanol group; and group O: octreotide group). Each rat was directly injected with a particular compound at the duodenal lobe of the pancreatic parenchyma. Each group was divided into three subgroups according to the time of post-injection sacrifice(1, 2, or 4 weeks). The hardness, suture holding capacity(SHC), and histological fibrosis grade of each pancreas were ***: The hardness, SHC, and fibrosis grade of groups E and O were increased at week 1, with greater increases in group E(all P < 0.001). In a subgroup comparison, the hardness, SHC, and fibrosis grade of group E tended to decrease gradually over time, with no regular pattern evident in group O. A comparison between the injected site(duodenal lobe) and non-injected site(splenic lobe) of the pancreas revealed increases in the three parameters of group E only in the duodenal lobe, with increases in group O at both the duodenal and splenic ***: Parenchymal injection of ethanol and octreotide increased pancreatic fibrosis. Unlike octreotide, ethanol provoked localized fibrosis that was maintained over time. It is expected that ethanol injection could eliminate POPF during pancreatic surgery.

关键词： Ethanol Octreotide Pancreatic fibrosis Pancreatic fistula Rat model

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Evaluation of prognostic factors on recurrence after curative resections for hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第45期20卷 17132-17140页

作者： Jae Hyun Han Dong Goo Kim Gun Hyung Na Eun Young Kim soo ho lee Tae ho hong Young Kyoung You Department of Surgery The Catholic University of Korea Seoul St.Mary’s Hospital

AIM: To select appropriate patients before surgical resection for hepatocellular carcinoma (HCC), especially those with advanced tumors.

关键词： Carcinoma Hepatocellular Hepatectomy Prognostic factor Survival Recurrence

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Inflammatory markers as selection criteria of hepatocellular carcinoma in living-donor liver transplantation

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World Journal of Gastroenterology 2014年第21期20卷 6594-6601页

作者： Gun Hyung Na Dong Goo Kim Jae hyun Han Eun Young Kim soo ho lee Tae ho hong Young Kyoung You Department of Surgery Seoul St. Mary’s HospitalThe Catholic University of KoreaSeoul 137-701South Korea

AIM: To investigate that inflammatory markers can predict accurately the prognosis of hepatocelluar carcinoma (HCC) patients in living-donor liver transplantation (LDLT).

关键词： C-reactive protein Hepatocellular carcinoma Liver transplantation Neutrophil-lymphocyte ratio Selection criteria

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Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi soo-ho Choi Keun-Young Kim Yury I.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye Institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and Imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

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论长江经济带对上海集装箱枢纽港形成的促进作用

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集装箱化 2001年第9期12卷 34-36页

作者：冯湛青李秀昊韩国海洋大学国际经贸学科

长江经济带是整个长江流域中最发达的地区,也是全国除沿海开放地区以外,经济密度最大的地带.上海港是中国第一大港,国际集装箱运输业近年来发展迅速(见表1),2000年的集装箱吞吐量更是达到561.2万TEU,跃居世界第六位.上海港之所以有如此... 详细信息

长江经济带是整个长江流域中最发达的地区,也是全国除沿海开放地区以外,经济密度最大的地带.上海港是中国第一大港,国际集装箱运输业近年来发展迅速(见表1),2000年的集装箱吞吐量更是达到561.2万TEU,跃居世界第六位.上海港之所以有如此骄人的成绩,是与长江经济带的发展密切相关的.

关键词：长江经济带集装箱枢纽港中国上海港国际集装箱运输发展集装箱吞吐量

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Influence of Aging Treatment on the Mechanical and Electrical Properties of Cu-0.5%Be Alloy

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Journal of Materials Science & Technology 2008年第1期24卷 120-122页

作者： Min Ryou Byoung-soo lee Myung-ho Kim School of Materials Science and Engineering Inha University 253 Yonghyun-DongNam-GuIncheon 402-751Korea Nano Material Team Korea Institute of Industrial Technology 7-47Songdo-DongYeonsu-GuIncheon 406-130Korea

The influence of aging treatment on the microstructure,mechanical properties and electrical conductivity of Cu-0.5 wt pct Be alloy for connector material applications was *** properties of mechanical strength and electrical conductivity increase with increasing aging temperature and *** of the aged Cu-Be alloy revealed that grain size and fraction of low angle and high angle grain boundary were not greatly changed;however,transmission electron microscopy （TEM） analysis exhibited that beryllides precipitation （CoBe and NiBe） with a size of 50 nm were distributed in *** was,therefore concluded that these beryllide precipitates improved the mechanical strength and also it was favor in improvement of electrical conductivity.

关键词： Cu-Be alloy Connector materials Beryllide precipitates

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Effect of Annealing Atmosphere on the Mechanical Property of Free-cutting Phosphor Bronze Alloy

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Journal of Materials Science & Technology 2008年第1期24卷 115-119页

作者： Byoung-soo lee hoon Cho Hyung-ho Jo Nano Material Team Advanced Material Division Korea Institute of Industrial Technology Incheon 406-800 Korea

The present work is focused on the influence of annealing atmosphere on the microstructure and mechanical property of free-cutting phosphor bronze *** annealing of the alloy was conducted in the three kinds of annealing atmosphere such as air,vacuum and *** annealing,a discernable difference in recystallized grain size and lead particle size was not appeared with different annealing *** tensile strength of the alloy annealed in air or nitrogen atmosphere was higher than that of those annealed in vacuum *** thecase of the alloy annealed in vacuum atmosphere,the mechanical strength was reduced by vaporization of *** the case of annealing in nitrogen and in air atmosphere,the sweating of lead was ***,the inverse segregation of lead was suppressed by copper oxide layer on the surface annealed in *** copper oxide layer leads to a decrease of the yield during fabrication process. Therefore,annealing of the alloy in nitrogen atmosphere is favorable in terms of the mechanical strength and yield.

关键词： Free-cutting Phosphor bronze alloy Inverse segregation Vaporization Sweating

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The effects of Y pre-alloying on the in-situ dispersoids of ODS Co Cr Fe Mn Ni high-entropy alloy

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Journal of Materials Science & Technology 2021年第26期85卷 62-75页

作者： SeungHyeok Chung Bin lee soo Yeol lee Changwoo Do ho Jin Ryu Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Manufacturing Technology Office Korea Institute for Rare MetalKorea Institue of Industrial TechnologyGet-Pearl TowerGaetbeol-ro 12Yeonsu-guIncheon 21999Republic of Korea Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Neutron Scattering Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Oxide dispersion strengthened CoCrFeMnNi high-entropy alloys(ODS-HEAs)were prepared using two different powder preparation methods classified by yttrium addition strategy to investigate the effects of in-situ and ex-situ oxide dispersoid formation on the microstructure and mechanical *** micro structural analysis was carried out by X-ray diffraction(XRD),electron backscattered diffraction(EBSD),high-resolution transmission electron microscopy(HRTEM),atom probe tomography(APT),and small-angle neutron scattering(SANS).Cryo-milled powder analysis,grain structure evolution after spark plasma sintering,dispersoid characteristics,and matrix/dispersoid interface structure analysis of the insitu and ex-situ dispersoids within the high-entropy alloy(HEA)matrix were *** in-situ dispersoid formation was dominantly observed in the Y-alloyed ODS-HEA through the construction of a coherent interface relationship with complex chemical composition,leading to an increase in the Zener pinning forces on the grain boundary ***-HEA with in-situ oxide dispersoids enhanced the formation of ultrafine-grained structures with an average diameter of 330 nm at a sintering temperature of 1173 *** study shows that the Y pre-alloying method is efficient in achieving fine coherent dispersoids with an ultra fine-grained structure,resulting in an enhancement of the tensile strength of the CoCrFeMnNi HEA.

关键词： Oxide dispersion strengthened(ODS)alloy High-entropy alloy In-situ oxide dispersoid formation Microstructure Mechanical property

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Radiologic evaluation of nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2014年第23期20卷 7392-7402页

作者： Seung soo lee Seong ho Park Department of Radiology and Research Institute of Radiology University of Ulsan College of MedicineAsan Medical CenterSeoul 138-736South Korea

Nonalcoholic fatty liver disease(NAFLD)is a frequent cause of chronic liver diseases,ranging from simple steatosis to nonalcoholic steatohepatitis(NASH)-related liver *** liver biopsy is still the gold standard for the diagnosis of NAFLD,especially for the diagnosis of NASH,imaging methods have been increasingly accepted as noninvasive alternatives to liver *** is a well-established and costeffective imaging technique for the diagnosis of hepatic steatosis,especially for screening a large population at risk of *** has a reasonable accuracy in detecting moderate-to-severe hepatic steatosis although it is less accurate for detecting mild hepatic steatosis,operator-dependent,and rather *** tomography is not appropriate for general population assessment of hepatic steatosis given its inaccuracy in detecting mild hepatic steatosis and potential radiation ***,computed tomography may be effective in specific clinical situations,such as evaluation of donor candidates for hepatic *** resonance spectroscopy and magnetic resonance imaging are now regarded as the most accurate practical methods of measuring liver fat in clinical practice,especially for longitudinal followup of patients with *** elastography and magnetic resonance elastography are increasingly used to evaluate the degree of liver fibrosis in patients with NAFLD and to differentiate NASH from simple *** article will review current imaging methods used to evaluate hepatic steatosis,including the diagnostic accuracy,limitations,and practical applicability of each *** will also briefly describe the potential role of elastography techniques in the evaluation of patients with NAFLD.

关键词： Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Liver steatosis Magnetic resonance spectroscopy Magnetic resonance imaging Ultrasonography Computed tomography Elastography

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Influence of operational parameters on the photocatalytic performance of DE-NOx process Via MIL-101(Fe)

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Progress in Natural Science:Materials International 2018年第6期28卷 689-695页

作者： hoang Phuc Nguyen Tae ho Kim soo Wohn lee Research Center for Eco Multi-Functional Nano Materials Sun Moon University Department of Environmental & Bio-Chemical Engineering Sun Moon University

Metal organic framework(MOF)has been paid great attention as a potential candidate for various applications in the field of energy and environment,particularly in air *** various MOFs,MIL-101(Fe) represents an interesting material possessing many advantages,including the ease of fabrication,high porosity,high specific surface area with open metal sites,making it a promising material in the field of harmful gas *** these advantages,MIL-101(Fe) was synthesized by facile microwave-solvothermal method and applied as a photocatalyst for the degradation of *** de-NOxefficiency of the synthesized powder was evaluated with respect to various operating parameters including substrates,sample doses,light spectrum and light intensity,initial NO concentration,and relative *** results have shown that the efficiency of NOxphotocatalytic degradation reaches to 77%under solar irradiation via 0.1 g of MIL-101(Fe) with optimum condition of reaction,(alumina substrate,350 ppb of initial NO concentration,40–50%of relative humidity).Then this work provides the optimum condition for the efficient photocatalytic degradation of NOx.

关键词： Metal-organic framework MIL-101 Gaseous pollutant NOx emission Photocatalyst

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