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Investigation of prodromal features in metabolic syndrome based on transcriptome analysis

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Genes & Diseases 2023年第3期10卷 708-711页

作者： Sang-Min Park Musun Park Hyo-Jeong Ban Su-jin Baek soo Yeon kim Siwoo Lee Hee-Jeong jin Korean Medicine(KM)Data Division Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea College of Pharmacy Chungnam National UniversityDaejeon 34134Republic of Korea

Metabolic syndrome(MetS)is a complex condition that significantly increases the risk of several diseases,including heart disease and *** with MetS show both pro-inflammatory and pro-thrombotic states;however,the state... 详细信息

关键词： diseases Metabolic Patients

High-performance solid-solution potassium-ion intercalation mechanism of multilayered turbostratic graphene nanosheets

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Journal of Energy Chemistry 2022年第4期31卷 814-823页

作者： Jiae Um Seung Uk Yoon Hoseong kim Beom Sik Youn Hyoung-Joon jin Hyung-Kyu Lim Young soo Yun Program in Environmental and Polymer Engineering Inha Universityncheon 22212 South Korea Department of Polymer Science and Engineering Inha UniversityIncheon 22212South Korea Division of Chemical Engineering and Bioengineering Kangwon National University Chuncheon Gangwon-do 24341 South Korea KU-KIST Graduate School of Converging Science and Technologyea University 145 Anam-roSeongbuk-guSoul02841 South Korea Department of Integrative Energy Engineering 145 Anam-roSongbuk-guKorea UniversitySeoul 02841 South Korea

The solid-solution reaction between an alkali cation and an active host material is known as a singlephase redox mechanism,and it is typically accompanied by a continuous voltage *** is distinct from the typical alkali cation intercalation reaction at an equivalent site of the active host material,which exhibits a voltage ***,we report an unusual solid-solution potassium-ion intercalation mechanism with a low-voltage plateau capacity on multilayered turbostratic graphene nanosheets(T-GNSs).Despite the disordered graphitic structure with a broad range of d-spacings(3.65–4.18À),the T-GNSs showed a reversible plateau capacity of~200 m A h g^(-1),which is higher than that of a well-ordered graphite nanoplate(~120 m A h g^(-1)).In addition,a sloping capacity of~220 m A h g^(-1)was delivered with the plateau capacity,and higher rate capabilities,better reversibility,and a more stable cycling performance were confirmed on the turbostratic ***-principles calculations suggest that the multitudinous lattice domains of the T-GNSs contain diverse intercalation sites with strong binding energies,which could be the origin of the high-performance solid-solution potassium-ion intercalation behavior when the turbostratic graphene stacks have a d-spacing smaller than that of equilibrium potassium–graphite intercalation compounds(5.35À).

关键词： Turbostratic graphite Graphene nanosheet Defective carbon Anode Potassium-ion batteries

Accurate Multi-Site Daily-Ahead Multi-Step PM_(2.5)Concentrations Forecasting Using Space-Shared CNN-LSTM

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Computers, Materials & Continua 2022年第3期70卷 5143-5160页

作者： Xiaorui Shao Chang soo kim Department of Information Systems Pukyong National UniversityBusan608737Korea

Accurate multi-step PM_(2.5)(particulate matter with diameters≤2.5 um)concentration prediction is critical for humankinds’health and air populationmanagement because it could provide strong evidence for ***,it is very challenging due to its randomness and *** paper proposed a novel method based on convolutional neural network(CNN)and long-short-term memory(LSTM)with a space-shared mechanism,named space-shared CNN-LSTM(SCNN-LSTM)for multi-site dailyahead multi-step PM_(2.5)forecasting with self-historical *** proposed SCNN-LSTM contains multi-channel inputs,each channel corresponding to one-site historical PM_(2.5)concentration *** which,CNN and LSTM are used to extract each site’s rich hidden feature representations in a stack ***,CNN is to extract the hidden short-time gap PM_(2.5)concentration patterns;LSTM is to mine the hidden features with long-time *** channel extracted features aremerged as the comprehensive features for future multi-step PM_(2.5)concentration ***,the space-shared mechanism is implemented by multi-loss functions to achieve space information ***,the final features are the fusion of short-time gap,long-time dependency,and space information,which enables forecasting more *** validate the proposed method’s effectiveness,the authors designed,trained,and compared it with various leading methods in terms of RMSE,MAE,MAPE,and R^(2)on four real-word PM_(2.5)data sets in Seoul,South *** massive experiments proved that the proposed method could accurately forecast multi-site multi-step PM_(2.5)concentration only using self-historical PM_(2.5)concentration time series and running ***,the proposed method obtained averaged RMSE of 8.05,MAE of 5.04,MAPE of 23.96%,and R^(2)of 0.7 for four-site daily ahead 10-hourPM_(2.5)concentration forecasting.

关键词： PM_(2.5)forecasting CNN-LSTM air quality management multi-site multi-step forecasting

Game Outlier Behavior Detection System Based on Dynamic Time Warp Algorithm

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Computer Modeling in Engineering & Sciences 2022年第4期131卷 219-237页

作者： Shinjin Kang soo Kyun kim School of Games Hongik UniversitySejong30016Korea Department of Computer Engineering Jeju National UniversityJeju63243Korea

This paper proposes a methodology for using multi-modal data in gameplay to detect outlier *** proposedmethodology collects,synchronizes,and quantifies time-series data fromwebcams,mouses,and *** expressions are varied on a one-dimensional pleasure axis,and changes in expression in the mouth and eye areas are detected ***,the keyboard and mouse input frequencies are tracked to determine the interaction intensity of ***,we apply a dynamic time warp algorithm to detect outlier *** detected outlier behavior graph patterns were the play patterns that the game designer did not intend or play patterns that differed greatly from those of other *** outlier patterns can provide game designers with feedback on the actual play experiences of users of the *** results can be applied to the game industry as game user experience analysis,enabling a quantitative evaluation of the excitement of a game.

关键词： Facial expression recognition webcam behavior analysis affective computing

On-skin and tele-haptic application of mechanically decoupled taxel array on dynamically moving and soft surfaces

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npj Flexible Electronics 2022年第1期6卷 964-972页

作者： Se Young Kwon Gyeongsuk Park Hanbit jin Changyeon Gu Seung jin Oh Joo Yong Sim Wooseup Youm Taek-soo kim Hye jin kim Steve Park Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Electronics and Telecommunications Research Institute(ETRI) Daejeon 34129Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Mechanical Systems Engineering Sookmyung Women’s UniversityDaejeon 04313Republic of Korea

To accurately probe the tactile information on soft skin,it is critical for the pressure sensing array to be free of noise and inter-taxel crosstalk,irrespective of the measurement ***,on dynamically moving and soft surfaces,which are common conditions for on-skin and robotic applications,obtaining precise measurement without compromising the sensing performance is a significant challenge due to mechanical coupling between the sensors and with the moving *** this work,multi-level architectural design of micro-pyramids and trapezoid-shaped mechanical barrier array was implemented to enable accurate spatiotemporal tactile sensing on soft surfaces under dynamic ***-off relationship between limit of detection and bending insensitivity was discovered,which was overcome by employing micropores in barrier ***,in-situ pressure mapping on dynamically moving soft surfaces without signal distortion is demonstrated while human skin and/or soft robots are performing complicated tasks such as reading Braille and handling the artificial organs.

关键词： artificial moving dynamically

Remarkably slow corrosion rate of high-purity Mg microalloyed with 0.05wt% Sc

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Journal of Magnesium and Alloys 2023年第3期11卷 991-997页

作者： soo-Min Baek Jeong-Ki kim Du-Won Min Sung soo Park Department of Materials Science and Engineering Ulsan National Institute of Science and TechnologyUlsan 44919Republic of Korea

We report that the corrosion resistance of Mg is significantly improved by adding 0.05wt%*** rates evaluated from weight loss values after room-temperature immersion in 0.6 M NaCl solution for two weeks were 0.27 and 4.0 mm y^(-1)for the high-purity Mg samples with and without microalloyed 0.05wt%Sc,*** beneficial effect of Sc microalloying on the corrosion resistance of Mg is discussed in connection with Sc-induced microstructural modifications.

关键词： Magnesium Microalloying Intermetallic phase Microgalvanic corrosion

Role of surfactants on particle deposition, wear, and corrosion behavior of TaC particle incorporated electroless nickel-phosphorus coating

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Progress in Natural Science:Materials International 2022年第5期32卷 655-663页

作者： jin-Hyuk Choi Dhani Ram Dhakal Yuwaraj K.Kshetri Bina Chaudhary Bhupendra Joshi soo Wohn Lee Tae-Ho kim Research Center for Advance Green Materials Sun Moon University Department of Fusion Science and Technology Sun Moon University

The coatings prepared by incorporating submicron-sized TaC particles while depositing Ni and P atoms on the steel substrate via electroless method showed mixed results of surface finishing, microstructural properties,mechanical, tribological, and corrosion behavior with the addition of various surfactants during the coating process. The surfactant sodium dodecyl sulfate(SDS) enhanced the microhardness when added during the coating process of Ni–P–TaC composite, whereas the cetyltrimethyl ammonium bromide(CTAB) lowered the microhardness as compared to the surfactant-free coating. Moreover, the TaC particle incorporation was hindered by the surfactants CTAB and Triton X-100. An excellent wear resistance behavior has been observed in the surfactantfree Ni–P–TaC coating in comparison to particle-free Ni–P coating. The Ni–P–TaC coatings showed the dependency of wear behavior on the material properties of the counter sliding surface although this dependency has not been observed in Ni–P coatings. The wear damage in Ni–P coating is immense irrespective of the properties of counter-sliding materials. Various surfactant-used Ni–P–TaC coating surfaces deteriorated much more due to corrosion than surfactant-free Ni–P–TaC coating. Among the various surfactants, the CTAB used Ni–P–TaC coating showed weak corrosion resistance.

关键词： Electroless coating NiP-based coating Tantalum carbide Wear Corrosion

Genome-wide DNA methylation profiling reveals candidate biomarkers and probable molecular mechanism of metabolic syndrome

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Genes & Diseases 2022年第4期9卷 833-836页

作者： Su-jin Baek Hyo-Jeong Ban Sang-Min Park soo Yeon kim Siwoo Lee Hee-Jeong jin KM Data Division Korea Institute of Oriental Medicine1672 Yuseong-daeroYuseong-guDaejeon 34054Republic of Korea

Although aberrant DNA methylation changes are significantly associated with the pathogenesis of many diseases,little is known about the molecular mechanisms underlying interactions between DNA methylation and gene expression in metabolic syndrome(MetS).The aim of this study was to identify biomarkers and molecular mechanisms regulated by DNA methylation in *** profiled genome-wide DNA methylation using the Infinium MethylationEPIC BeadChIP and characterized the transcriptome by RNA sequencing in our study population comprised of subjects with MetS(n=11)and controls(n=9).

关键词： diseases pathogenesis EPIC

Fibrillary gelation and dedoping of PEDOT:PSS fibers for interdigitated organic electrochemical transistors and circuits

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npj Flexible Electronics 2022年第1期6卷 330-340页

作者： Young jin Jo soo Young kim Jeong Hun Hyun Byeonghak Park Seunghwan Choy Gyan Raj Koirala Tae-il kim School of Chemical Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Biomedical Institute for Convergence(BICS) Sungkyunkwan University(SKKU)Suwon 16419Korea

As one of conducting polymers,PEDOT:PSS,is commonly used in organic electronics,especially for bioelectronics due to its advantages such as high electrical and ionic conductivity,solution-processability and *** bioelectronics with the PEDOT:PSS requires advanced techniques to obtain physical/chemical modification of the PEDOT:PSS for improved performance and various *** satisfy these demands,fibrillary gelation of PEDOT:PSS by injection to choline acetate,an ionic liquid,with a constant flow rate was used in this study to make a conductive fiber and improve characteristics of PEDOT:*** fibers by fibrillary gelation showed enhanced electrical conductivity of about 400 S cm^(-1) and volumetric capacitance of about 154 F cm^(−3) which would be strongly beneficial to be utilized for organic electrochemical transistors(OECTs),resulting in a high transconductance of 19 mS in a ***,dedoping of the conductive fibers by PEI(polyethyleneimine)enabled the creation of enhancement-mode *** inverters were then fabricated by connecting depletion and enhancement-mode *** results demonstrate that these conductive fibers and electronic-textiles are suitable candidates for applications in bio-integrated electronics.

关键词： fibers doping digit