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Research in Astronomy and Astrophysics 2021年第10期21卷 197-208页

作者： cheng cheng Jia-Sheng Huang Hai Xu Gao-Xiang Jin Chuan He Tian-wen Cao Zi-Jian Li Shu-mei wu Piao-Ran Liang Ya-Ru Shi Xu Shao YSophia Dai Cong Kevin Xu marat musin Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China

The Spitzer Extended Deep Survey(SEDS)as a deep and wide mid-infrared(mIR)survey project provides a sample of 500000+sources spreading 1.46 square degree and a depth of 26 AB mag(3σ).Combining with the previous available data,we build a PSF-matched multi-wavelength photometry catalog from u band to 8μ*** fit the SEDS galaxies spectral energy distributions by the local galaxy *** results show that the SEDS galaxy can be fitted well,indicating the high redshift galaxy(z~1)shares the same templates with the local *** study would facilitate the further study of the galaxy luminosity and high redshift mass function.

关键词： cosmology:observations galaxies:high-redshift galaxies:evolution galaxies:statistics infrared:galaxies

〈533〉轴向取向稀土超磁致伸缩合金棒的制备与性能

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材料工程 2008年第4期36卷 5-7,73页

作者：江民红顾正飞成钢成钧赵家城桂林电子科技大学信息材料科学与工程系广西桂林541004

利用非自耗真空电弧熔炼炉,通过恰当控制熔炼温度和热流方向,成功生长了具有〈533〉轴向取向的多晶稀土-铁系超磁致伸缩合金棒材。对其磁致伸缩性能测试结果表明,所制备的棒材具有较高的磁致伸缩应变,在0mPa压应力、400 kA.m-1的磁场下... 详细信息

利用非自耗真空电弧熔炼炉,通过恰当控制熔炼温度和热流方向,成功生长了具有〈533〉轴向取向的多晶稀土-铁系超磁致伸缩合金棒材。对其磁致伸缩性能测试结果表明,所制备的棒材具有较高的磁致伸缩应变,在0mPa压应力、400 kA.m-1的磁场下,其轴向饱和磁致伸缩系数λ//达1045×10-6,饱和磁致伸缩系数λS为856×10-6。X射线衍射结果表明,该材料在轴向主要有(533)强衍射峰,同时还具有(311),(110)等弱峰;径向则有(110),(220),(311),(511)等衍射峰,但各峰强度均很弱,证明该方向上的取向性不如轴向。另外,本实验还对超磁致伸缩材料的磁滞回线进行了测试分析。

关键词：磁致伸缩〈533〉取向材料制备磁滞回线

2型糖尿病患者度拉糖肽降糖疗效的影响因素回顾性分析

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中国医院药学杂志 2024年第8期44卷 911-915页

作者：张云轩欧阳义峰周海峰吴建博高宁舟钱程郑松柏陈志龙复旦大学附属华东医院药剂科上海200040 上海健康医学院药学院上海201318 复旦大学附属华东医院消化内科上海200040

目的:评估度拉糖肽对2型糖尿病(type 2 diabetic mellitus,T2Dm)患者的降糖等疗效,并分析降糖疗效的影响因素,为促进度拉糖肽临床应用提供依据。方法:以复旦大学附属华东医院2020年6月至2022年6月间首次使用度拉糖肽的T2Dm患者为研究对... 详细信息

目的:评估度拉糖肽对2型糖尿病(type 2 diabetic mellitus,T2Dm)患者的降糖等疗效,并分析降糖疗效的影响因素,为促进度拉糖肽临床应用提供依据。方法:以复旦大学附属华东医院2020年6月至2022年6月间首次使用度拉糖肽的T2Dm患者为研究对象,采用回顾性分析方法,观察和比较患者首次使用度拉糖肽6个月及以上前后的降糖疗效,及体质量疗效指标的变化。另将患者分成降糖疗效达标[治疗后糖化血红蛋白(glycated hemoglobin,HbA1c)1%]和疗效未达标组,对基线数据进行单因素分析,包括基本信息、检验指标、合并用药情况等,并随访比较2组间的不良事件,logistic回归法筛选出降糖疗效的影响因素。结果:159例T2Dm患者首次使用度拉糖肽6个月及以上后,HbA1c、空腹血糖、体质量、体重指数(body mass index,BmI)分别下降(0.91±1.60)%、(0.61±2.60)mmol·L^(–1)、(1.41±3.02)kg、(0.45±1.02)kg·m^(–2),差异均具有统计学意义(Pm患者首次使用度拉糖肽治疗6个月及以上,HbA1c、空腹血糖、体质量、BmI显著下降。患者的糖尿病病程、基线HbA1c水平、首次使用前的降糖药种类数在度拉糖肽降糖疗效分组间存在差异,基线HbA1c水平是影响度拉糖肽疗效的主要因素,基线HbA1c较高的患者用药后的疗效更佳。

关键词：度拉糖肽降糖疗效影响因素回顾分析

Lean-non-alcoholic fatty liver disease increases risk for metabolic disorders in a normal weight Chinese population

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world Journal of Gastroenterology 2014年第47期20卷 17932-17940页

作者： Ren-Nan Feng Shan-Shan Du cheng wang Yan-Chuan Li Li-Yan Liu Fu-Chuan Guo Chang-Hao Sun Department of Nutrition and Food Hygiene School of Public HealthHarbin Medical University Department of Environmental Hygiene School of Public HealthHarbin Medical University

AIm: To study the prevalence and clinical biochemical, blood cell and metabolic features of lean-non-alcoholic fatty liver disease (lean-NAFLD) and its association with other diseases.

关键词： Lean-non-alcoholic fatty liver disease metabolic disorder Diabetes Risk Chinese

Confinement fluorescence effect of an aggregation-induced emission luminogen in crystalline polymer

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Aggregate 2023年第5期4卷 112-119页

作者： Lan Zhou Linlin Zheng Xiaoxiao Yu mengyue Gao chengjian Xu Yifan Ge Tianxiang Bai Jin wen Yanhua cheng meifang Zhu State Key Laboratory for modification of Chemical Fibers and Polymer materials College of Materials Science and EngineeringDonghua UniversityShanghaiChina

Despite the impressive progress of stimuli-responsive fluorescent materials,little is known about the influence of confinement created by crystalline polymer over the fluorescence properties of fluorescent *** effects of confinement on the fluorescence of an aggregation-induced emission luminogen(AIEgen)are investigated using computational simulations,which reveal that the confined space induces the AIEgens to take a more planar conformation,resulting in a red-shifted emission *** this property,the study is extended to explore the confinement generated by various polymer crystalline forms,and it is shown that different fluorescence colors are *** confinement fluorescence effect is attributed to the different spatial dimensions of the polymer amorphous layer between lamellar crystals where the AIEgens are *** results indicate the immediate association between crystalline structure and fluorescence signals,activating unprecedented photophysical properties of luminescent materials,and also providing the possibility for crystalline structure visualization,it is important for the many polymer crystallization processes occurring in the materials processing.

关键词： aggregation-induced emission confinement fluorescence effect polymer crystalline structure

TOPOLOGICAL CONFIGURATIONS OF POSSIBLE REAL NETS IN BINARY n+m(m≥3) PHASE mULTISYSTEmS

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Science in China,Ser.B 1986年第10期29卷 1096-1109页

作者：程伟基 Department of Earth and Space Sciences University of Science and Technology of China Hefei

This paper further summarizes the method and results developed to find all possible real nets in binary n+3 phase multisystems, and emphasizes that there is a definite relationship between configurations and symbols of stable and metastable invariant points of nets or positions of phases as symbols on the chemographic bar. On the basis of these, a general principle is developed to construct and check possible neets in binary n+m (m>3) phase multisysterns: this sort of nets must be the reasonable combination of one or more than one distinct binary n+3 phase multisystem subnets, in which the number of points missing respectively same m—3 phases in n+3. Therefore, the binary n-4-3 phase nets are basic construction units of the binary n+m(m>3) phase nets. As an instance, the maximum partially closed net in binary n+4 phase multisystems, which has the most stable invariant points, is constructed, and it is indicated that this sort of net is unique.

关键词： PHASE mULTISYSTEmS TOPOLOGICAL CONFIGURATIONS OF POSSIBLE REAL NETS IN BINARY n+m net NETS

2D and 3D Shape Sensing Based on 7-Core Fiber Bragg Gratings

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Photonic Sensors 2020年第4期10卷 306-315页

作者： Tianting LAI Pu cheng Congliao YAN Chi LI wenbin HU minghong YANG National Engineering Laboratory for Fiber Optic Sensing Technology Wuhan University of TechnologyWuhan 430070China

A fiber-optic shape sensing based on 7-core fiber Bragg gratings(FBGs)is proposed and experimentally *** investigations are presented for two-dimensional(2D)and three-dimensional(3D)shape reconstruction by distinguishing bending and twisting of 7-core optical fiber with *** curvature and bending orientation can be calculated by acquiring FBG wavelengths from any two side cores among the six outer *** the shape sensing in 3D space is computed by analytic geometry *** experiments corresponding of 2D and 3D shape sensing are demonstrated and conducted to verify the theoretical *** resolution of curvature is about 0.1 m^(-1) for 2D *** error of angle in shape reconstruction is about 1.89°for 3D *** proposed sensing technique based on 7-core FBGs is promising of high feasibility,stability,and repeatability,especially for the distinguishing ability on the bending orientation due to the six symmetrical cores on the cross-section.

关键词： Shape sensing fiber Bragg gratings multi-core fiber

Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis

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Bioactive materials 2021年第3期6卷 721-728页

作者： wenguang Liu min wang wei cheng wen Niu mi Chen meng Luo Chenxi Xie Tongtong Leng Long Zhang Bo Lei Frontier Institute of Science and Technology Xi'an Jiaotong UniversityXi'an710054PR China Key Laboratory of Shaanxi Province for Craniofacial Precision medicine Research College of StomatologyXi'an Jiaotong UniversityXi'an710000China National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an710000China Instrument Analysis Center Xi'an Jiaotong UniversityXi'an710054China

The efficient cutaneous wound healing accompanied with the enhanced skin appendage regeneration is still a *** bacterial infection and excessive/prolonged inflammation inhibit wound healing process and result in the scar ***,we reported an anti-inflammatory polycitrate-polyethyleneimine-Ibuprofen(PCEI)and multifunctional PCEI-based F127-ε-polypeptide-alginic(FEA)dressing(FEA-PCEI)for accelerating wound healing and hair follicle *** showed the excellent anti-inflammation function through stimulating macrophage towards anti-inflammatory m2 subtype *** FEA-PCEI dressing showed the temperature-response gelation,injectability,robust antibacterial activity,light-damage-resistant,homeostasis ability,and good *** optimized dosage of FEA-PCEI dressing could significantly accelerate wound healing with anti-infection ability,reduce the scar formation,and promote the hair follicle *** study provided a wound-repairing strategy through regulating the phenotype of immune cells by the designing bioactive multifunctional biomaterials.

关键词： Bioactive dressing Polycitrate Anti-inflammation Antibacterial wound healing

Structure modification,antialgal,antiplasmodial,and toxic evaluations of a series of new marine-derived 14-membered resorcylic acid lactone derivatives

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marine Life Science & Technology 2022年第1期4卷 88-97页

作者： wei-Feng Xu Na-Na wu Yan-wei wu Yue-Xuan Qi mei-Yan wei Laura m.Pineda michelle G.Ng Carmenza Spadafora Ji-Yong Zheng Ling Lu Chang-Yun wang Yu-cheng Gu Chang-Lun Shao Key Laboratory of marine Drugs the Ministry of Education of ChinaSchool of Medicine and PharmacyOcean University of ChinaQingdao266003China Laboratory for marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and TechnologyQingdao266237China State Key Laboratory for marine Corrosion and Protection Luoyang Ship Material Research Institute(LSMRI)Qingdao266237China Center of Cellular and molecular Biology of Diseases Instituto de Investigaciones Científcas y Servicios de Alta TecnologíaCity of KnowledgeClaytonApartado0816-02852Panama Syngenta Jealott’s Hill International Research Centre BracknellBerkshireRG426EYUK

marine natural products play critical roles in the chemical defense of many marine organisms and are essential,reputable sources of successful drug ***-seven 14-membered resorcylic acid lactone derivatives 3–27 and 30–71 of the natural product zeaenol(1)isolated from the marine-derived fungus Cochliobolus lunatus were semisynthesized by chlorination,acylation,esterification,and acetalization in one to three *** structures of these new derivatives were established by HRESImS and NmR *** the compounds(1–71)were evaluated for their antialgal and antiplasmodial *** them,14 compounds displayed antifouling activities against adhesion of the fouling *** particular,9 and 34 exhibited strong and selective inhibitory effects against the diatoms Navicula laevissima and Navicula exigua(EC50=6.67 and 8.55μmol/L),respectively,which were similar in efficacy to those of the positive control SeaNine 211(EC50=2.90 and 9.74μmol/L).more importantly,38,39,and 69–71 showed potent antiplasmodial activities against Plasmodium falciparum with IC50 values ranging from 3.54 to 9.72μmol/*** interestingly,the five antiplasmodial derivatives displayed non-toxicity in the cytotoxicity assays and the zebrafish embryos model,thus,representing potential promising antiplasmodial drug *** preliminary structure–activity relationships indicated that biphenyl substituent at C-2,acetonide at positions C-5′and C-6′,and tri-or tetra-substituted of acyl groups increased the antiplasmodial ***,combining evaluation of chemical ecology with pharmacological models will be implemented as a systematic strategy,not only for environmentally friendly antifoulants but also for structurally novel drugs.

关键词： marine natural product 14-membered resorcylic acid lactone Zeaenol Semisynthesis Antialgal activity Antiplasmodial activity

Blueberry malvidin-3-galactoside modulated gut microbial dysbiosis and microbial TCA cycle KEGG pathway disrupted in a liver cancer model induced by HepG2 cells

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Food Science and Human wellness 2020年第3期9卷 245-255页

作者： Zhen cheng Jie Lin Ningxuan Gao Xiyun Sun Xianjun meng Ruihai Liu Yunen Liu weisheng wang Bin Li Yuehua wang College of Food Science Shenyang Agricultural UniversityLiaoningChina National R&D Professional Center For Berry Processing Shenyang Agricultural UniversityLiaoningChina Key Laboratory of Healthy Food Nutrition and Innovative manufacturing of Liaoning China Department of food Science Cornell UniversityIthacaNYUSA Emergency medicine Department of General Hospital of Shenyang military Command Laboratory of Rescue Center of Severe Trauma PLALiaoningChina Shenyang Blueberry Industry Co.LTD. LiaoningChina

HCC(Hepatocellular Carcinoma)is a critical health issue *** previous animal experiment has confirmed that blueberry malvidin-3-galactoside(m3G)can regulate the progression of *** this study,feces samples from the same batch of mice were collected to explore the regulatory mechanism of m3G on intestinal microbiota and microbial TCA cycle metabolism KEGG pathway in HCC mice based on 16S rRNA sequencing and *** results showed that blueberry m3G increased the microbial diversity and regulated the structure of intestinal microbiota in mice,such as increasing the abundance of Clostridia(butyric acid-producing bacteria),Oscillospira and Ruminococcus,and reducing the abundance of pathogenic *** with the group of liver cancer and 5-fluorouracil,blueberry m3G significantly regulated microbial TCA cycle KEGG pathway via improving the expression of key proteins(porA,DLAT,aceE,PC and OGDH).Additionally,we found which the abundance of muribaculum intestinale increased by blueberry m3G may be an important factor affecting the microbial TCA cycle KEGG pathway via the pearson correlation(R)analysis of protein and *** together,these results demonstrate that the blueberry m3G has the potential to be an intestinal microbiota regulator and an adjuvant to HCC therapy.

关键词： Blueberry malvidin-3-galactoside HCC metagenomics microbial TCA cycle KEGG pathway