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Physicochemical conditions in affecting the distribution of spring phytoplankton community

Chinese Journal of Oceanology and Limnology 2017年第6期35卷 1342-1361页

作者：魏玉秋刘海娇张晓东薛冰 MUNIR sonia 孙军 College of Marine and Environmental Sciences Tianjin University of Science and Technology Tianjin 300457 China Tianjin Key Laboratory of Marine Resources and Chemistry Tianjin University of Science and Technology Tianjin 300457 China Institute of Marine Science and Technology Shandong University Jinan 250110 China

To better understand the physicochemical conditions in af fecting regional distribution of phytoplankton community, one research cruise was carried out in the Bohai Sea and Yellow Sea during 3 rd and 23 th May, 2010. The phytoplankton community, including Bacillariophyta(105 taxa), Pyrrophyta(54 taxa), Chrysophyta(1 taxon) and Chlorophyta(2 taxa), had been identified and clearly described from six ecological provinces. And, the six ecological provinces were partitioned based on the top twenty dominant species related with notable physicochemical parameters. In general, the regional distributions of phytoplankton ecological provinces were predominantly influenced by the physicochemical properties induced by the variable water masses and circulations. The predominant diatoms in most of water samples showed well adaptability in turbulent and eutrophic conditions. However, several species of dinoflagellates e.g., Protoperidinium conicum, Protoperidinium triestinum, Protoperidinium sp. and Gymnodinium lohmanni preferred warmer, saltier and nutrient-poor environment. Moreover, the dinoflagellates with high frequency in the Yellow Sea might be transported from the Yellow Sea Warm Current. The horizontal distribution of phytoplankton was depicted by diatoms and controlled by phosphate concentration, while the vertical distribution was mainly supported by light and nutrients availability in the subsurface and bottom layers, respectively.

关键词： phytoplankton physicochemical conditions ecological provinces Bohai Sea Yellow Sea

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Laparoscopic management of a giant mucinous benign ovarian mass weighing 10150 grams:A case report

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World Journal of Clinical Cases 2020年第16期8卷 3527-3533页

作者： Elisabetta Sanna Clelia Madeddu Luca Melis sonia Nemolato Antonio Macciò Department of Gynecologic Oncology Azienda Ospedaliera BrotzuCagliari 09100Italy Department of Medical Sciences and Public Health University of CagliariMonserrato 09042Italy Department of Nuclear Medicine Azienda Ospedaliera BrotzuCagiari 09100Italy Department of Pathology Azienda Ospedaliera BrotzuCagliari 09100Italy

BACKGROUND Giant ovarian cysts(≥15 cm in diameter)are *** size limit of cysts and the methodology for a safe and successful minimally invasive surgery has not been *** we report a case of a large 10-kg multi-locular ovarian mass,which was successfully laparoscopically removed:Our aim was to innovate the surgical practice in this field by providing a safe,effective,and minimally invasive management method for such complex and rare *** SUMMARY A 49-year-old nulliparous woman presented with abdominal distension,lasting from six Mo prior to admission;she reported worsening abdominal pain,abdominal swelling,and mild *** showed a presumed benign multi-locular(>10 locules)left ovarian cyst that measured about 30 cm in *** on the IOTA-ADNEX model the mass had a 27.5%risk of being a borderline or malignant *** patient was successfully treated via a direct laparoscopic approach with salpingo-oophorectomy,followed by the external drainage of the *** spillage was successfully avoided during this *** final volume of the drained mucinous content was 8950 L;the cyst wall,extracted through the minilaparotomy,weighed about 1200 *** pathologic gross examination revealed a 24 cm×15 cm×10 cm mass;the histologic examination diagnosed a mucinous *** our knowledge,this is the first case of a giant multi-locular ovarian cyst treated with a direct laparoscopy with salpingo-oophorectomy followed by external *** Choosing the appropriate technique and surgeon skill are necessary for a safe and effective minimally-invasive approach of unique cases involving giant ovarian cysts.

关键词： Giant ovarian cyst Minimally-invasive surgery Laparoscopy Benign ovarian mass Spillage Case report

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Genome-based nutrition:An intervention strategy for the prevention and treatment of obesity and nonalcoholic steatohepatitis

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World Journal of Gastroenterology 2015年第12期21卷 3449-3461页

作者： sonia Roman Claudia Ojeda-Granados Omar Ramos-Lopez Arturo Panduro Department of Molecular Biology in Medicine Civil Hospital of Guadalajara "Fray Antonio Alcalde"GuadalajaraJalisco Mexico and Health Sciences Center University of Guadalajara

Obesity and nonalcoholic steatohepatitis are increasing in westernized countries, regardless of their geographiclocation. In Latin America, most countries, including Mexico, have a heterogeneous admixture genome with Amerindian, European and African ancestries. However, certain high allelic frequencies of several nutrientrelated polymorphisms may have been achieved by past gene-nutrient interactions. Such interactions may have promoted the positive selection of variants adapted to regional food sources. At present, the unbalanced diet composition of the Mexicans has led the country to a 70% prevalence rate of overweightness and obesity due to substantial changes in food habits, among other factors. International guidelines and intervention strategies may not be adequate for all populations worldwide because they do not consider disparities in genetic and environmental factors, and thus there is a need for differential prevention and management strategies. Here, we provide the rationale for an intervention strategy for the prevention and management of obesity-related diseases such as nonalcoholic steatohepatitis based on a regionalized genome-based diet. The components required to design such a diet should focus on the specific ancestry of each population around the world and the convenience of consuming traditional ethnic food.

关键词： Latin America Mexico Gene-nutrient interactions Ev

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Genes, emotions and gut microbiota:The next frontier for the gastroenterologist

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World Journal of Gastroenterology 2017年第17期23卷 3030-3042页

作者： Arturo Panduro Ingrid Rivera-Iniguez Maricruz Sepulveda-Villegas sonia Roman Department of Molecular Biology in Medicine Civil Hospital of Guadalajara“Fray Antonio Alcalde” Health Sciences Center University of Guadalajara

Most medical specialties including the field of gastroenterology are mainly aimed at treating diseases rather than preventing them. Genomic medicine studies the health/disease process based on the interaction of the human genes with the environment. The gastrointestinal(GI) system is an ideal model to analyze the interaction between our genes, emotions and the gut microbiota. Based on the current knowledge, this mini-review aims to provide an integrated synopsis of this interaction to achieve a better understanding of the GI disorders related to bad eating habits and stress-related disease. Since human beings are the result of an evolutionary process, many biological processes such as instincts, emotions and behavior are interconnected to guarantee survival. Nourishment is a physiological need triggered by the instinct of survival to satisfy the body's energy demands. The brain-gut axis comprises a tightly connected neuralneuroendocrine circuitry between the hunger-satiety center, the dopaminergic reward system involved in the pleasure of eating and the gut microbiota that regulates which food we eat and emotions. However, genetic variations and the consumption of high-sugar and high-fat diets have overridden this energy/pleasure neurocircuitry to the point of addiction of several foodstuffs. Consequently, a gut dysbiosis generates inflammation and a negative emotional state may lead to chronic diseases. Balancing this altered processes to regain health may involve personalized-medicine and genome-based strategies. Thus, an integrated approach based on the understanding of the gene-emotions-gut microbiota interaction is the next frontier that awaits the gastroenterologist to prevent and treat GI disorders associated with obesity and negative emotions.

关键词： Genes Emotions Brain reward system Gut microbiota Gastrointestinal disease Personalized medicine Genome-based nutrition Nutrigenetics Food decision-making Obesity

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The road to opportunities： landscape change promotes body-size divergence in a highly mobile species

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Current Zoology 2016年第1期62卷 7-14页

作者： Carlos CAMACHO Pedro SAEZ sonia SANCHEZ Sebastian PALACIOS Carlos MOLINA Jaime POTTI Department of Evolutionary Ecology Estacion Biologica de Donana--CSIC Av. Americo Vespucio 41092 SevilleSpain Department of Environmental Biology and Public Health. University of Huelva. Av. Andalucia 21071 HuelvaSpain Department of Conservation Biology Estacion Biologica de Donana--CSlC Av. Americo Vespucio 41092Seville Spain Sociedad Espafiola de Ornitologia. Centro Ornitologico Francisco Bernis. Paseo Marismeno sn 21750 Huelva Spain

Landscape change provides a suitable framework for investigating population-level responses to novel ecological pressures. However, relatively little attention has been paid to examine the poten- tial influence of landscape change on the geographic scale of population differentiation. Here, we tested for morphological differentiation of red-necked nightjars Caprimulgus ruficollis breeding in a managed property and a natural reserve situated less than 10 km apart. At both sites, we also esti- mated site fidelity over 5 years and quantified the potential foraging opportunities for nightjars. Breeding birds in the managed habitat were significantly larger in size--as indexed by keel length--than those in the natural one. However, there were no significant differences in wing or tail length. Immigration from neighboring areas was almost negligible and, furthermore, no individual （out of 1130 captures overall） exchanged habitats between years, indicating strong site fidelity. Food supply for nightjars was equally abundant in both habitats, but the availability of foraging sites was remarkably higher in the managed property. As a result, nightjars--particularly fledg- lings-in the latter habitat benefited from increased foraging opportunities in relation to those in the natural site. It seems likely that the fine-scale variation in nightjar morphology reflects a pheno- typic response to unequal local conditions, since non-random dispersal or differential mortality had been determined not to be influential. High site fidelity appears to contribute to the mainten- ance of body-size differences between the two habitats. Results from this nightjar population high- light the potential of human-induced landscape change to promote population-level responses at exceedingly small geographic scales.

关键词： human-induced environmental change morphology phenotypic divergence philopatry population differentiation.

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Formaldehyde vapour sensing property of electrospun NiO nanograins

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Frontiers of Materials Science 2021年第3期15卷 416-430页

作者： Roopa Kishore KAMPARA sonia T. Balamurugan D. Jeyaprakash B.G. Functional Nanomaterials Lab/School of Electrical&Electronics Engineering SASTRA Deemed to be UniversityThanjavurTamil Nadu 613401India

Beads free polyvinyl alcohol(PVA)/NiO nanofibers with an average diameter of 400 nm were successfully prepared through the electrospinning *** nanograins were formed along the axis of the nanofiber due to the calcination of asspun fibers for 24 h at 450℃ and their presence was confirmed by *** nanograins were characterized by XRD,XPS and *** characterization results showed the presence of NiO in nanograins and its polycrystalline nature with ionic *** sensing studies of NiO nanograins were performed towards the pulmonary disease breath markers and they showed better response towards formaldehyde vapour at 350℃.Calcined NiO grains showed a good response towards the 11-1145 ppm of formaldehyde vapour at the operating temperature of 350℃.NiO nanograins also showed quick response time(37 s)and recovery time(14 s)towards 46 ppm of formaldehyde.A sensing mechanism was proposed for the formaldehyde vapour interaction at 350℃ with NiO nanograins.

关键词： electrospinning nanofibers nanograins PVA vapour sensor NiO formaldehyde

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Ontogenetic transition in leaf traits: a new cost associated with the increase in leaf longevity

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Journal of Plant Ecology 2014年第6期7卷 567-575页

作者： sonia Mediavilla Maria Herranz Patricia González-Zurdo Alfonso Escudero Departamento de Ecología Facultad de BiologíaUniversidad de SalamancaSalamanca 37071Spain

Aims Recent work has identified a worldwide‘economics’spectrum of correlated leaf traits that mainly reflects the compromises between maximizing leaf longevity and short-term ***,during the early stages of tree growth different species tend to exhibit a common strategy,because competition for soil water and nutrients forces the maximization of short-term productivity owing to the need for rapid growth during the most vulnerable part of the tree’s life ***,our aim here was to compare the variations that occur during ontogeny in the different leaf traits(morphology and leaf chemical composition)of several coexisting Mediterranean woody species differing in their leaf life spans and to test our hypothesis that tree species with a long leaf life span should exhibit larger shifts in leaf characteristics along *** Six Mediterranean tree species differing in leaf life span,selected from three plots located in central-western Spain,were studied during three growth stages:seedlings,juveniles and mature *** life span,leaf morphology(leaf area,dry weight,thickness and mass per unit area)and chemical composition(N and fibre con-centrations)were measured in all six *** magnitude of the ontogenetic changes in the different traits was estimated and related to the mean leaf longevity of the different *** Findings Along ontogeny,strong changes were observed in all variables *** early growth stages showed lower leaf thickness,leaf thickness and mass per unit area and N,cellulose and hemi-cellulose concentrations than mature trees,but a higher lignin ***,these changes were especially marked in species with a longer leaf life span at *** dif-ferences in leaf life span,leaf morphology and chemical com-position were stronger at the mature stage than at the seedling *** conclude that greater plasticity and more intense strat-egy shifts along ontogeny are necessarily associ

关键词： leaf morphology leaf N concentration fibre content Pinus Quercus tree age class

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Complex Assembly and Metabolic Profiling of Arabidopsis thaliana PlantsOverexpressing Vitamin B6 Biosynthesis Proteins

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Molecular Plant 2010年第5期3卷 890-903页

作者： Jan Erik Leuendorf sonia Osorio Agnieszka Szewczyk Alisdair R. Fernie Hanjo Hellmann Angewandte Genetik Freie Universitat Berlin 14195 Berlin Germany Max-Planck-lnstitut for Molekulare Pflanzenphysiologie Potsdam-Golm 14476 Germany Pharmaceutical Faculty of the Collegium Medicum Jagiellonian University Krakow Poland School of Biological Sciences Washington State University Pullman USA

In plants, vitamin B6 biosynthesis requires the activity of PDX1 and PDX2 proteins. Arabidopsis thaliana encodes for three PDX1 proteins, named PDXI.1, 1.2, and 1.3, but only one PDX2. Here, we show in planta complex assembly of PDX proteins, based on split-YFP and FPLC assays, and can demonstrate their presence in higher complexes of around 750 kDa. Metabolic profiling of plants ectopically expressing the different PDX proteins indicates a negative influence of PDX1.2 on vitamin Be biosynthesis and a correlation between aberrant vitamin B6 content, PDX1 gene expression, and light sensitivity specifically for PDX1.3. These findings provide first insights into in planta vitamin B6 synthase complex assembly and new information on how the different PDX proteins affect plant metabolism.

关键词： Abiotic/environmental stress metabolomics metabolic regulation molecular physiology.

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Microbiological Quality of Cyperus esculentus L. Products Sold in Ouagadougou and Bobo Dioulasso (Burkina Faso)

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Open Journal of Applied Sciences（应用科学） 2024年第3期 635页

作者： Zénabou Semdé Passinguemsin Alice sonia Tiendrebeogo Bahanla Edwige Oboulbiga Charles Parkouda Hagrétou Sawadogo Lingani

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Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells

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World Journal of Stem Cells 2020年第11期12卷 1410-1428页

作者： Petra Jagust sonia Alcala Bruno Sainz Jr Christopher Heeschen Patricia Sancho Molecular Pathology Programme Spanish National Cancer Research Centre(CNIO)Madrid 28029Spain Department of Biochemistry Autónoma University of MadridInstituto de Investigaciones Biomédicas"Alberto Sols"CSIC-UAMMadrid 28029Spain Center for Single-Cell Omics&Key Laboratory of Oncogenes and Related Genes Shanghai Cancer InstituteShanghai Jiao Tong University School of MedicineShanghai 200025China Hospital Universitario Miguel Servet IIS AragonZaragoza 50009Spain

BACKGROUND Cellular metabolism regulates stemness in health and disease.A reduced redox state is essential for self-renewal of normal and cancer stem cells(CSCs).However,while stem cells rely on glycolysis,different CSCs,including pancreatic CSCs,favor mitochondrial metabolism as their dominant energy-producing *** suggests that powerful antioxidant networks must be in place to detoxify mitochondrial reactive oxygen species(ROS)and maintain stemness in oxidative *** glutathione metabolism is critical for normal stem cell function and CSCs from breast,liver and gastric cancer show increased glutathione content,we hypothesized that pancreatic CSCs also rely on this pathway for ROS *** To investigate the role of glutathione metabolism in pancreatic *** Primary pancreatic cancer cells of patient-derived xenografts(PDXs)were cultured in adherent or CSC-enriching sphere conditions to determine the role of glutathione metabolism in ***-time polymerase chain reaction(PCR)was used to validate RNAseq results involving glutathione metabolism genes in adherent vs spheres,as well as the expression of pluripotency-related genes following *** TCGA and GTEx RNAseq data from pancreatic cancer vs normal tissue samples were analyzed using the webserver *** glutathione-sensitive fluorescent probe monochlorobimane was used to determine glutathione content by fluorimetry or flow *** inhibitors of glutathione synthesis and recycling[buthionine-sulfoximine(BSO)and 6-Aminonicotinamide(6-AN),respectively]were used to investigate the impact of glutathione depletion on CSC-enriched *** with propidium iodide(cell cycle),Annexin-V(apoptosis)and CD133(CSC content)were determined by flow ***-renewal was assessed by sphere formation assay and response to gemcitabine treatment was used as a readout for *** Analysis of our previously published RNAseq dataset E-MTAB-

关键词： Pancreatic cancer Cancer stem cells Glutathione Self-renewal Chemoresistance Redox

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