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CONTRIBUTION OF CYTOGENETIC ANALYSIS IN THE LYMPHOMA TUMORS

Open Journal of Rheumatology and Autoimmune Diseases（风湿病与自身免疫疾病期刊） 2023年第1期

作者： Sanjida Pervin sonia Ellen Ferdous Mohammad Imnul Islam Shahana Akhter Rahman

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癌变．畸变．突变 1991年第S1期3卷 275-275页

作者： sonia Rombout J.Collignon D.Bazzoni Ch.Laurent Genetic Toxicology Unit-Dept of Oncology University of Lige-Belgium Genetic Toxicology Unit-Dept of Oncology University of Lige-BelgiumGenetic Toxicology Unit-Dept of Oncology University of Lige-BelgiumGenetic Toxicology Unit-Dept of Oncology University of Lige-Belgium

Since the discovery of chromosomal abnormalitiesspecifically linked to particular types of leukemia,cytogeneticstudies have been shown to be of great contribution not only forthe diagnosis of leukemia but also for prognosis of *** is less clear for patients with lymphoma for whichcells are generally more difficult to grow in culture.

关键词： chromosomal prognosis indicators

Clinical and Ultrasound Concordance of Joint Damages in Rheumatoid Arthritis in a Resource-Limited Country

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Open Journal of Radiology 2021年第3期11卷 126-137页

作者： sonia B. M. G. Adjadohoun Miralda Kiki Maurice M. W. D. Akanni Boris Vidégla Perpétue Batcho Kofi-Mensa S. Savi de Tovè Patricia Yèkpè Ahouansou Zavier C. Zomalheto Olivier Biaou Vicentia Boco Medical Imaging Department Faculty of Health Sciences University of Abomey Calavi Cotonou Republic of Benin Regional and Teaching Hospital of Borgou/Medical Imaging Department Faculty of Medicine University of Parakou Parakou Republic of Benin Rheumatology Department Faculty of Health Sciences University of Abomey Calavi Cotonou Republic of Benin

Introduction: Rheumatoid arthritis (RA) is the most common chronic inflammatory rheumatism. The increasing use of bone and joint ultrasound as a tool to aid in the detection of unrefined synovitis in developed countries, has led us to study the performance of ultrasound in the diagnosis of RA in subjects consulting in rheumatology at Cotonou. Study Method: Descriptive cross-sectional study of patients with RA, selected on the basis of ACR/ EULAR 2010 criteria. A complete clinical examination with imaging including X-rays and ultrasounds of the hands and feet were performed in all patients who have given their consent. The data collected was analyzed using EPI data 3.1 and SPSS 24.0 software. The significance rate was defined with a p-value Results: All 53 patients included had lesions on ultrasound. Synovitis was found in 98.1% and bone erosions in 88.7%. There was no agreement in the wrists between clinical examination and ultrasound (k = -0.116), MCP (k = -0.097) and MTP (k = -0.031). Agreement was very low at the PPI level (k = 0.03). It was low at the different sites, between ultrasound and radiographic detection of lesions (k between 0.022 - 0.22). Age, positive immunologic RA factor and biological inflammatory syndrome were associated with ultrasound erosions (p = 0.0001) and only age was associated with active synovitis (p = 0.022). Conclusion: Bone and articular ultrasound is a good complementary alternative to clinical examination and radiography diagnostic in early diagnosis of RA in our developing countries, in the absence of MRI which remains a luxury.

关键词： Rheumatoid Arthritis Ultrasound Erosions Synovitis Cotonou

Optimal Risk-Sensitive Filtering for System Stochastic of Second and Third Degree

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Lipocalin-2 as a biomarker for diabetic nephropathy

Intelligent Control and Automation（智能控制与自动化） 2011年第1期

作者： Ma Aracelia Alcorta-Garcia sonia Gpe Anguiano Rostro Mauricio Torres Torres

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World Journal of Meta-Analysis 2023年第4期11卷 92-101页

作者： Kiran Dahiya Praveen Prashant Rakesh Dhankhar Kumud Dhankhar Sushil Kumar sonia Vashist Department of Biochemistry Pt BD Sharma Post Graduate Institute of Medical SciencesRohtak 124001HaryanaIndia Department of Radiation Oncology Pt BD Sharma Post Graduate Institute of Medical SciencesRohtak 124001India Phase III JSS Medical CollegeMysuru 570015KarnatakaIndia Civil Hospital Jhajjar 124103HaryanaIndia Department of Dermatology Dr Sonia’s Dermatology ClinicRewari 123401HaryanaIndia

Diabetes is a major global public health *** prevalence of type 1 diabetes is comparatively static,as hereditary and genetic causes are involved,while type 2 diabetes(T2D)prevalence is increasing day by day.T2D is associated with chronic complications,including diabetic neuropathy(DN),nephropathy,retinopathy,and other complications like diabetic *** is the main complication of both types of *** can be diagnosed by routine laboratory tests,microalbuminuria>300 mg/24 h,and a gradual decrease in glomerular filtration *** the appearance of microalbuminuria is a late manifestation,an early marker for renal damage is ***-2,also known as neutrophil gelatinaseassociated lipocalin(NGAL),is a small protein purified from neutrophil granules and a good marker for kidney *** is a transporter protein responsible for many physiological processes,such as inflammation,generation of the immune response,and metabolic *** has been reported to depict the early changes in renal damage when urine microalbumin is still ***,elucidating the role of NGAL in detecting DN and understanding its mechanism can help establish it as a potential early marker for DN.

关键词： Type 1 diabetes Type 2 diabetes Diabetic nephropathy Lipocalin-2 Early biomarkers for kidney disease Acute kidney injury

Seasonal Variability in the Distribution of Phytoplankton in Paracas Bay/Peru, as a Response to Environmental Conditions

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Journal of Environmental Science and Engineering(B) 2019年第1期8卷 7-16页

作者： sonia Sánchez Nelly Jacobo Avy Bernales Augusto Franco Jorge Quispe Georgina Flores Laboratory of Phytoplankton and Primary Production Instituto del Mar del Peru Chucuito Callao 07001 Peru Functional Area of Research in Physical Oceanography Instituto del Mar del Peru Chucuito Callao 07001 Peru Functional Area of Research in Chemical Oceanography Instituto del Mar del Peru Chucuito Callao 07001 Peru

During 2013-2015, a series of bio-oceanographic surveys was carried out in Paracas bay (13°50′ S). This coastal habitat represents a transition between open ocean and continent. Changes in distribution and structure of phytoplankton community and presence of noxious algal blooms were evaluated. The vertical stability of water column was analyzed on transects of temperature, salinity and potential density. Stratification of the water column as well as other variables presented a seasonal behavior. The maximum values were recorded in summer and were directly related to the seasonal heat flux in surface layers of the bay, while in winter this stratification index was minimum. N/P ratios showed a seasonal variation with highest values in winter and lowest ones in summer. Silicate concentrations were minimum mainly during in spring due to high biological fixation. The dominance of diatoms was evident in winter and spring, with maximum abundances of r strategists. The diversity and equitability indexes were low (< 3 bits?cel^-1 and 0.31, respectively). During summer, there was a greater contribution of oceanic species, with high concentrations of the dinoflagellate Prorocentrum cordatum;and a higher frequency of algal blooms (Akashiwo sanguinea, Heterosigma akashiwo, Eutreptiella gymnastica and Gonyaulax polygramma) in the coastal zone. Silicates and pH presented a significant correlation with diatom abundances in spring, whilst dinoflagellates were associated to warm and salinity conditions in summer. Weak correlations were found for potentially toxic dinoflagellates with temperature and for Pseudo-nitzschia group with silicates and phosphates.

关键词： HAB transition zones inshore ecosystem Paracas bay-Peru phytoplankton

Association of Host Interferon-γ Gene Polymorphism with Toxoplasma gondii Infection in Pregnant Women of Bangladesh

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American Journal of Molecular Biology（美国分子生物学期刊） 2023年第3期

作者： Nasrin Akter sonia Tamanna Molie Rahman Atiqur Rahman Akm Mahbub Hasan Taibur Rahman

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披甲树螽

环球人文地理 2016年第5期 112-112页

作者：张山 sonia Soma

面对比自己强大的对手时,不同的生物有自己独特的防御方式,或飞速逃离现场,或变色与环境融为一体……而活跃在非洲大陆的披甲树螽的防御方式,却充满了血腥。披甲树螽是直翅目螽斯科的一种,体型硕大,四肢粗壮,外壳坚硬,全身长满硬刺,可... 详细信息

面对比自己强大的对手时,不同的生物有自己独特的防御方式,或飞速逃离现场,或变色与环境融为一体……而活跃在非洲大陆的披甲树螽的防御方式,却充满了血腥。披甲树螽是直翅目螽斯科的一种,体型硕大,四肢粗壮,外壳坚硬,全身长满硬刺,可谓非洲昆虫界的霸主之一。生物界的争斗是异常残酷的,再强大的昆虫也会被捕食。对于不会飞的披甲树

关键词：鬃狮蜥反流物有毒液体贝特曼防御方式雌性个体攻击者

Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis

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Rheumatology & Autoimmunity 2023年第1期3卷 15-25页

作者： Yi Tong V.Aw Phillip J.Whiley Ayla May Lorenzo Tom Lea-Henry Somasundhari Shanmuganandam Maurice Stanley sonia N.Babu Vicki Athanasopoulos Jean Cappello Julia I.Ellyard Matthew Cook Carola Vinuesa Giles Walters David A.Fulcher Simon H.Jiang Division of Medicine The Canberra HospitalGarranAustralian Capital TerritoryAustralia The Australian National University Medical School GarranAustralian Capital TerritoryAustralia Department of General Surgery The Canberra HospitalGarranAustralian Capital TerritoryAustralia Department of Immunology and Infectious Disease John Curtin School of Medical ResearchGarranAustralian Capital TerritoryAustralia Centre for Personalized Immunology NHMRC Centre for Research ExcellenceCanberraAustralia Department of Renal Medicine The Canberra HospitalGarranAustralian Capital TerritoryAustralia Department of Immunology The Canberra HospitalCanberraAustralian Capital TerritoryAustralia

Background:Systemic lupus erythematosus(SLE)is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan *** involvement,termed lupus nephritis,has major impact on life *** is increasingly recognized that SLE is likely a common clinical manifestation of pathophysiologically diverse processes,and lupus nephritis has similarly been associated with several distinct immunological *** compared the immune cell phenotypes of individuals with SLE in the presence or absence of ***:Cryopreserved peripheral blood mononuclear cells from SLE patients with and without kidney involvement underwent flow cytometric analysis to identify major populations in T cells,B cells and myeloid ***:We compared the frequencies of lymphocyte populations in 69 SLE patients without nephritis,20 SLE patients with nephritis,and 92 healthy blood *** with SLE and lupus nephritis(LN)had reduced marginal zone B cells(P<0.0001 in SLE;P=0.001 in LN),memory B cells(P=0.002 in SLE;P=0.001 in LN)and circulating T follicular helper(Tfh)memory cells(P<0.0001 in SLE and LN)compared to healthy *** with lupus nephritis had increase Th2(P<0.0001)and T regulatory cells(P<0.0001)compared to both SLE patients without nephritis and healthy ***:SLE patients with and without lupus nephritis have distinct immunologic differences that may reflect the unique pathophysiological processes contributing to disease manifestations.

关键词： immunoprofiling lupus nephritis systemic lupus erythematosus

Progression of Platelet Counts in Treatment Naïve HIV/HCV Co-Infection

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World Journal of AIDS 2013年第1期3卷 36-40页

作者： Jonathan E. Schelfhout Danijela A. Stojanovic Amy Houtchens Heidi M. Crane Edward R. Cachay Elizabeth R. Brown sonia M. Napravnik Mari M. Kitahata Michael S. Saag Peter W. Hunt Teresa L. Kauf Joseph A. C. Delaney Department of Epidemiology University of Washington Seattle WA Department of Medicine University of Alabama at Birmingham Birmingham USA Department of Medicine University of California at San Diego San Diego USA Department of Medicine University of California at San Francisco San Francisco USA Department of Medicine University of North Carolina Chapel Hill USA Division of Allergy & Infectious Disease Department of Medicine University of Washington Seattle USA Food and Drug Administration Silver Spring USA Vaccine and Infectious Disease and Public Health Sciences Divisions Fred Hutchinson Cancer Research Center Seattle USA

Background: Previous research has suggested an association between infection with hepatitis C virus (HCV) or with human immunodeficiency virus (HIV) and low platelet counts. This study estimates platelet count changes over time in HIV/HCV co-infected participants and compares them with the changes in platelet count among HIV mono-infected participants to test if HIV/HCV co-infection is associated with lower platelet counts. Methods: This retrospective cohort study included all HIV treatment naive patients from four sites in the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort with platelet count measurements between 2002 and 2009. We conducted a mixed effects linear regression modeling the mean change in platelet count per year while adjusting for age, sex, race, baseline CD4 cell count, and site. Index date was the first platelet count after 2002, and participants were censored upon initiation of treatment for HIV or HCV. Results: There were 929 HIV/HCV co-infected and 3558 HIV mono-infected participants with a mean follow-up time of 1.2 years. HIV/HCV co-infected participants had on average a slighter lower platelet count at baseline (234,040 vs. 242,780/μL;p-value = 0.004), and a more rapid mean reduction per year (7230 vs. 3580/μL;p-value 0.001) after adjusting for age, sex, baseline CD4 count. Conclusions: In treatment naive participants, HIV/HCV co-infection is associated with a more rapid decline in platelet count compared with HIV mono-infection.

关键词： HCV HIV AIDS Co-Infection Platelet Count Thrombocytopenia