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Laparoscopic coring-type resection of noncommunicating broadly attached rudimentary horn with recurrent large ovarian endometriomas:A report of two cases

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Laparoscopic, Endoscopic and Robotic Surgery 2023年第1期6卷 31-34页

作者： Jianmin chen Dong Huang Libing Shi songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province Hangzhou 310016China Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology Hangzhou 310016China

Rudimentary horn of the uterus is a rare congenital malformation that is characterized by significant anatomic *** report two cases involving women who presented with a broadly attached rudimentary horn and large ovarian endometriomas that were innovatively treated by laparoscopic coring-type dissection of the rudimentary horn of the *** novel surgical approach ensured the integrity of the myometrium of the unicornuate uterus and avoided uterine rupture during pregnancy and ipsilateral ovarian function impairment.

关键词： Laparoscopic Rudimentary horn Coring-type dissection Ovarian function

一种模拟沸石分子筛扩散反应的Monte　Carlo方法

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燃料化学学报 1994年第4期22卷 355-361页

作者：王建国李永旺陈诵英彭少逸中国科学院山西煤炭化学研究所

在考虑了沸石分子筛中吸附、脱附、扩散和反应的特点的基础上，发展了一种模拟沸石分子筛中扩散反应的ＭｏｎｔｅＣａｒｌｏ方法。用Ｌａｎｇｍｕｉｒ吸附等温式验证了该方法的合理性，并证明了轰击频率λ代表了反应物气相压力，而吸附... 详细信息

在考虑了沸石分子筛中吸附、脱附、扩散和反应的特点的基础上，发展了一种模拟沸石分子筛中扩散反应的ＭｏｎｔｅＣａｒｌｏ方法。用Ｌａｎｇｍｕｉｒ吸附等温式验证了该方法的合理性，并证明了轰击频率λ代表了反应物气相压力，而吸附、脱附几率之比即为吸附平衡常数。同时，通过改变轰击频率λ和反应几率Ｐ＿ｒ，得到了吸附等温线和有效因子随Ｔｈｉｅｌｅ模数变化的曲线。

关键词：形状选择性沸石分子筛扩散反应蒙特卡罗法

Prevention,diagnosis,and management of interstitial pregnancy:A review of the literature

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Laparoscopic, Endoscopic and Robotic Surgery 2019年第1期2卷 12-17页

作者： Jianmin chen Dong Huang Libing Shi songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalZhejiang University School of MedicineKey Laboratory of Reproductive Dysfunction Management of Zhejiang ProvinceHangzhou 310016China

Objective:The incidence of interstitial pregnancy(IP)has increased by using assisted reproductive technology,especially after ipsilateral *** review aimed to examine the current state of prevention,risk factors,diagnosis,and management of IP,based on the current *** sources:We searched PubMed for English language articles published up to June *** search terms included interstitial pregnancy,ectopic pregnancy or cornual pregnancy,angular pregnancy,and combinations of these *** selection:Articles were obtained and reviewed to analyze risk factors,diagnosis,prevention,and management of ***:Ipsilateral salpingectomy is the main high-risk factor of IP,especially after in vitro *** suture at the time of salpingectomy helps to reduce the IP *** cornuostomy appears to be an effective treatment in intact cases,although it sometimes needs to be combined with methotrexate therapy in ruptured cases complicated by persistent disease.

关键词： Laparoscopic cornuostomy Interstitial pregnancy Cornual suture Salpingectomy

The cervical function and pregnancy outcomes after hysteroscopic resection of the complete uterine septum,duplicate cervix and vaginal septum

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Laparoscopic, Endoscopic and Robotic Surgery 2019年第2期2卷 31-33页

作者： Dong Huang Lingyan Zhang Jianmin chen songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalZhejiang University School of Medicine/Key Laboratory of Reproductive Dysfunction Management of Zhejiang ProvinceHangzhou 310016China

Objective:To evaluate cervical function and pregnancy outcomes after hysteroscopic resection of the complete uterine septum,duplicate cervix and vaginal septum with Metzenbaum ***:Between January 2010 and December 2016,13 patients admitted to the Department of Obstetrics and Gynecology of Sir Run Run Shaw Hospital with complete uterine septum,duplicate cervix and vaginal septum,were enrolled into this *** cervical and corporal septum was cut by Metzenbaum scissors,and residual septum was cut by micro scissors under *** vaginal septum was cut with the unipolar electric ***:The operation time was about 10±1.31 *** the 13 patients present normal uterine cavities without scar formation under hysteroscopy at 3 months after operation,there was mild adhesions between anterior and posterior intrauterine wall on 2 *** operation,there were 13 pregnancies naturally conceived in 11 patients,10 *** live birth rate was 76.92%,the early miscarriage rate was 23.08%.The cesarean section ratewas 30%,the vaginal delivery ratewas 70%,and all were term ***:The operation was simple,convenient,and fast,without any complications and cervical *** was easy to have vaginal deliveries.

关键词： Hysteroscopic metroplasty Cervical function Pregnancy outcomes

Effect of modified laparoscopic salpingectomy on ovarian reserve:Changes in the serum antimüllerian hormone levels

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Laparoscopic, Endoscopic and Robotic Surgery 2019年第1期2卷 8-11页

作者： Dong Huang Yunshan Zhu Jianmin chen songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalZhejiang University School of MedicineKey Laboratory of Reproductive Dysfunction Management of Zhejiang ProvinceHangzhou 310016China

Objective:To retrospectively estimate the impact of modified laparoscopic salpingectomy on the ovarian reserve in infertile ***:There were 74 infertile women undergone modified laparoscopic salpingectomy from June 2016 to January 2017,and their levels of serum antimüllerian hormone,basal follicle-stimulating hormone and estradiol were reviewed ***:No significant change was detected in serum antimüllerian hormone at 3 months after surgery compared to preoperative level(p=0.857).Similar changes were observed for the basal follicle-stimulating hormone(p=0.102)and estradiol(p=0.233)***:Our results revealed that modified laparoscopic salpingectomy might be a valuable treatment for hydrosalpinx before in vitro fertilization.

关键词： Modified laparoscopic salpingectomy Ovarian reserve Serum antimüllerian hormone

In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel:A therapy for intrauterine adhesions

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Bioactive Materials 2022年第6期7卷 107-119页

作者： Liaobing Xin cheng Wei Xiaomei Tong Yangyang Dai Dong Huang Jianmin chen Lie Ma songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou310016China MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou310027China Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province.No.3 Qingchun East Road Jianggan DistrictHangzhou310016China

Stem cell-based and stem cell-derived exosome-based therapies have shown promising potential for endometrial regeneration and the clinical treatment of intrauterine adhesions(IUAs).Evidence shows that apoptosis occurs in a majority of grafted stem cells,and apoptotic bodies(ABs)play a critical role in compensatory tissue ***,the therapeutic potential of AB-based therapy and its mechanism have not been explored in ***,a cell-free therapeutic strategy was developed by incorporating mesenchymal stem cell-derived ABs into a hyaluronic acid(HA)hydrogel to achieve endometrial regeneration and fertility ***,we found that the ABs could induce macrophage immunomodulation,cell proliferation,and angiogenesis in *** HA hydrogel promoted the retention of ABs and facilitated their continuous *** a murine model of acute endometrial damage and a rat model of IUAs,in situ injection of the AB-laden HA hydrogel could efficiently reduce fibrosis and promote endometrial regeneration,resulting in the fertility ***,ABs show good potential as therapeutic vesicles,and the AB-laden HA hydrogel appears to be a clinically feasible and cell-free alternative for endometrial regeneration and IUA treatment.

关键词： Apoptotic bodies Mesenchymal stem cells Endometrial regeneration Intrauterine adhesions Tissue engineering

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嗜肺军团菌效应蛋白之间的调控机制

中国细胞生物学学报 2024年第2期46卷 336-344页

作者：康丽娜黄诗晴陈涛涛欧阳松应福建师范大学生命科学学院福州350117 福建师范大学南方生物医学研究中心福州350117

嗜肺军团菌(Legionella pneumophila)是一种革兰氏阴性致病菌,它可以引起人类军团病。嗜肺军团菌的Dot/Icm分泌系统在其致病过程中至关重要,其向宿主细胞内转运约330种效应蛋白,通过修饰细胞调节因子、抑制细胞凋亡等一系列措施操纵宿... 详细信息

嗜肺军团菌(Legionella pneumophila)是一种革兰氏阴性致病菌,它可以引起人类军团病。嗜肺军团菌的Dot/Icm分泌系统在其致病过程中至关重要,其向宿主细胞内转运约330种效应蛋白,通过修饰细胞调节因子、抑制细胞凋亡等一系列措施操纵宿主细胞的多种生命活动,以完成自身的增殖与侵染。为避免对宿主生理造成不必要的破坏,嗜肺军团菌已进化出复杂而精细的调控机制来平衡嗜肺军团菌毒力与宿主细胞的稳态,以确保嗜肺军团菌在宿主细胞内的生存。军团菌效应蛋白的功能及分子机制的研究近几年取得突破性进展,嗜肺军团菌效应蛋白之间的作用机理也成为我们进一步研究的热点。该文主要对嗜肺军团菌的致病机制及其效应蛋白间的调控机制进行了综述,为进一步了解嗜肺军团菌致病机制提供了一定的参考。

关键词：嗜肺军团菌 Dot/Icm分泌系统效应蛋白相互作用

Outcomes of patients who have undergone laparoscopic abdominal cerclage:A retrospective study

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Laparoscopic, Endoscopic and Robotic Surgery 2022年第3期5卷 111-115页

作者： Cuiyu Yang Dong Huang Yang Yang Jingyan Yang Yuyang chen Mei Pan songying Zhang Assisted Reproduction Unit Department of Obstetrics and GynecologySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Objective:This study aims to evaluate the surgical morbidity and obstetric outcomes following in-pregnancy or pre-pregnancy laparoscopic abdominal cerclage(LAC)for patients who were diagnosed with refractory cervical insufficiency or had a short ***:A retrospective study was conducted on patients undergoing LAC between May 2017 and May 2019 at the Department of Obstetrics and Gynecology,Sir Run Run Shaw *** patients were diagnosed with refractory cervical insufficiency based upon a previous failed transvaginal cervical cerclage(TVC),or had a short cervix who were considered unsuitable for a TVC after a previous cervical *** patients were followed-up after surgery with transperineal ultrasonography until May ***,surgical and obstetric data were collected and ***:In total,44 patients underwent LAC,with 8 patients in-pregnancy and 36 *** the patient with pre-pregancy LAC,the pregnancy rate was 80.6%(29/36),including 3 patients with first-trimester loss,1 patient with an ectopic pregnancy,and 25 patients with a *** the remaining 7 patients,3 did not conceive,and another 4 had no pregnancy *** the patients with in-pregnancy LAC had a ***“take-home baby”rate was 89.2%(33/37),with a live-birth rate of 100%and a neonatal survival rate of 100%for both patients with in-pregnancy and pre-pregnancy *** patients with in-pregnancy LAC,75.0%(6/8)patients delivered at≥37 wk of gestation,12.5%(1/8)delivered between 34 and 36^(+6)wk,and 12.5%(1/8)delivered between 28 and 33^(+6)*** patients with pre-pregnancy LAC,80.0%(20/25)patients delivered at≥37 wk of gestation,16.0%(4/25)delivered between 34 and 36^(+6)wk,and 4.0%(1/25)delivered between 28 and 33^(+6)*** adverse-event intra-operative or post-operative sequelae were ***:LAC is an effective and safe procedure that results in remarkable obstetric outcomes for women with refractory cervical insufficiency,or with a sh

关键词： Cervical cerclage Cervical insufficiency Laparoscopic Conization Preterm birth

超细Pd／Al_2O_3催化剂及其对乙炔选择加氢催化性能研究

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天然气化工—C1化学与化工 1996年第5期21卷 14-18页

作者：高荫本章斌关春梅陈诵英中国科学院山西煤炭化学研究所煤转化国家重点实验室

用超临界干燥方法制备超细Ｐｄ／Ａｌ２Ｏ３催化剂，研究了制备方法、表面物性、活性组分的化学态及乙炔选择加氢反应催化活性。表明超细Ａｌ２Ｏ３担体为短纤维状，Ｐｄ／Ａｌ２Ｏ３催化剂的结构特征是高比表面、大孔径和低表面酸性。... 详细信息

用超临界干燥方法制备超细Ｐｄ／Ａｌ２Ｏ３催化剂，研究了制备方法、表面物性、活性组分的化学态及乙炔选择加氢反应催化活性。表明超细Ａｌ２Ｏ３担体为短纤维状，Ｐｄ／Ａｌ２Ｏ３催化剂的结构特征是高比表面、大孔径和低表面酸性。Ｐｄ与担体有强相互作用，呈Ｐｄ４＋态。

关键词：超临界干燥催化剂乙炔选择加氢