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Decomposition Method of Genetic Correlation Coefficient Based on NC Ⅱ Mating Design

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Asian Agricultural Research 2017年第1期9卷 76-77,80页

作者： Wei WANG Zheng WANG Fengzhi WANG songshan zhao Xiuzhen CUI Cangzhou Academy of Agriculture and Forestry Sciences China Petroleum Materials Corporation Life Science and Technology College Henan Institute of Science and Technology

There are different degrees of correlation between crop traits. The phenotypic correlation is decomposed into genetic and environmental correlation in quantitative genetics. In this paper,according to stochastic model of variance and covariance analysis,we calculate different genetic components,bring up a decomposition method of genetic correlation coefficient based on NC II mating design,and use examples to show analytic steps and interpret results.

关键词： Analysis of variance Analysis of covariance Stochastic model Genetic correlation coefficient

Effects of Different Water Treatment on Yield and Agronomic Traits of Wheat

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Asian Agricultural Research 2018年第3期10卷 83-87页

作者： Weiwei WANG Liang YU Liya NIU Wei WANG Li LU Fengzhi WANG songshan zhao Cangzhou Academy of Agricultural and Forestry Sciences Cangzhou 061001 China

In order to make clear the effects of water on yield and agronomic traits of wheat in Cangzhou,18 wheat cultivars from north part of Huanghuai Plain were collected for spring irrigation. The indoor and field surveys were used to analyze the effects of irrigation frequency on stem tiller situation,leaf area coefficient,yield and other traits of different wheat cultivars. The results indicated that the average yield of irrigation 1 increased by 68. 07 kg compared with that of irrigation 0,while the average yield of irrigation 2 increased by 60. 00 kg compared with that of irrigation 1. The survey of flag leaf area of wheat cultivars at the grain filling stage showed that the leaf area of irrigation 0 was the smallest( 18. 15 cm^2 on average),the leaf area of irrigation 1 was 20. 34 cm^2,and the leaf area of irrigation 2 was 24. 05 cm^2. With the increase in the irrigation times,the volume weight of wheat cultivars declined,the number of infertile spikelet dropped,and the plant height gradually increased. In conclusion,every decrease of one time of irrigation times,there will be loss of yield about 60. 00 kg.

关键词： Wheat Yield Irrigation Agronomic traits

Selection and Breeding of Drought Resistant,Water-saving and High-yield Wheat Variety Cangmai 028

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Asian Agricultural Research 2017年第2期9卷 33-34,38页

作者： Liang YU Liya NIU Jing FU Fengzhi WANG songshan zhao Li LU Weiwei WANG Cangzhou Academy of Agricultural and Forestry Sciences

Cangmai 028 was selected and bred according to the climatic characteristic of the winter wheat in Heilonggang Basin taking 98(083)as the female parent and the Canghe 030 as the male parent by "two-row parallel alternate selection" method.Cangmai 028 has characteristics of high resistance,water-saving,high and stable yield,and rich genetic background.This study elaborated selection and breeding background and methods,characteristics,quality,and yield of Cangmai 028.

关键词： Cangmai 028 Drought resistance Variety Selection and breeding technology

Advances in Studies of Biological Nitrogen Saving Technology for Wheat

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Asian Agricultural Research 2018年第2期10卷 87-89,94页

作者： Liya NIU Liang YU Wei WANG Weiwei WANG Jing FU Fengzhi WANG songshan zhao Cangzhou Academy of Agricultural and Forestry Sciences Cangzhou 061001 China

This paper first described the current status of wheat nitrogen fertilizers utilization rate. Then,from balanced fertilizer application,applying slow/controlled release fertilizer,deep application of nitrogen fertilizers and graded application,controlled application amount,selection of application time according to soil properties,diagnosed application of fertilizer with instrument,addition of synergist,and precise fertilizer application,it summarized biological nitrogen saving methods and introduced prospects of future biological nitrogen saving technology.

关键词： Wheat Fertilizer utilization rate Biological nitrogen saving method

Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1637-1650页

作者： Yuanliang Yan Shangjun Zhou Xi Chen Qiaoli Yi songshan Feng Zijin zhao Yuanhong Liu Qiuju Liang Zhijie Xu Zhi Li Lunquan Sun Department of Pharmacy Xiangya HospitalCentral South UniversityChangsha 410008China Department of Neurosurgery Xiangya HospitalCentral South UniversityChangsha 410008China Department of Pathology Xiangya HospitalCentral South UniversityChangsha 410008China Xiangya Cancer Center Xiangya HospitalCentral South UniversityChangsha 410008China Key Laboratory of Molecular Radiation Oncology Hunan Province Changsha 410008China institute of Cancer Research National Clinical Research Center for Geriatric Disorders(Xiangya)Xiangya HospitalCentral South UniversityChangsha 410008China

Temozolomide(TMZ)represents a standard-of-care chemotherapeutic agent in glioblastoma(GBM).However,the development of drug resistance constitutes a significant hurdle in the treatment of malignant glioma.Although specific innovative approaches,such as immunotherapy,have shown favorable clinical outcomes,the inherent invasiveness of most gliomas continues to make them challenging to treat.Consequently,there is an urgent need to identify effective therapeutic targets for gliomas to overcome chemoresistance and facilitate drug development.This investigation used mass spectrometry to examine the proteomic profiles of six pairs of GBM patients who underwent standard-of-care treatment and surgery for both primary and recurrent tumors.A total of 648 proteins exhibiting significant differential expression were identified.Gene Set Enrichment Analysis(GSEA)unveiled notable alterations in pathways related to METABOLISM_OF_LIPIDS and BIOLOGICAL_OXIDATIONS between the primary and recurrent groups.Validation through glioma tissue arrays and the Xiangya cohort confirmed substantial upregulation of inositol 1,4,5-triphosphate(IP3)kinase B(ITPKB)in the recurrence group,correlating with poor survival in glioma patients.In TMZ-resistant cells,the depletion of ITPKB led to an increase in reactive oxygen species(ROS)related to NADPH oxidase(NOX)activity and restored cell sensitivity to TMz.Mechanistically,the decreased phosphorylation of the E3 ligase Trim25 at the S100 position in recurrent GBM samples accounted for the weakened ITPKB ubiquitination.This,in turn,elevated ITPKB stability and impaired ROS production.Furthermore,ITPKB depletion or the ITPKB inhibitor GNF362 effectively overcome TMZ chemoresistance in a glioma xenograft mouse model.These findings reveal a novel mechanism underlying TMZ resistance and propose ITPKB as a promising therapeutic target forTMZ-resistant GBM.

关键词： TMZ homeostasis impaired

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关于技术进步与经济增长关系的若干思考

统计研究 1998年第2期15卷 40-44页

作者：白雪梅赵松山东北财经大学

关于技术进步与经济增长关系的若干思考白雪梅赵松山ＡＢＳＴＲＡＣＴＴｗｏｉｓｓｕｅｓｗｅｒｅｄｉｓｃｕｓｓｅｄ．Ｔｈｅｆｉｒｓｔｏｎｅｉｓｈｏｗｔｏｍｅａｓｕｒｅｔｈｅｃｏｎｔｒｉｂｕｔｉｏｎｏｆｔｅｃｈｎｉｃａｌｐｒ... 详细信息

关于技术进步与经济增长关系的若干思考白雪梅赵松山ＡＢＳＴＲＡＣＴＴｗｏｉｓｓｕｅｓｗｅｒｅｄｉｓｃｕｓｓｅｄ．Ｔｈｅｆｉｒｓｔｏｎｅｉｓｈｏｗｔｏｍｅａｓｕｒｅｔｈｅｃｏｎｔｒｉｂｕｔｉｏｎｏｆｔｅｃｈｎｉｃａｌｐｒｏｇｒｅｓｓｔｏｔｈｅｅｃｏｎｏｍ...

关键词：技术进步经济增长理论研究

Highly uniform Co-Cu bimetallic sulfides for rechargeable alkaline aqueous zinc batteries

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Chinese Chemical Letters 2024年第2期35卷 521-526页

作者： Xiaofang Bai Yuwei zhao Mangwei Cui Tianshuo Guo Zijie Tang Chuan Li Heng Gao Shuo Yang Lingzhi zhao Chunyi Zhi Hongfei Li Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055China songshan Lake Materials Laboratory Dongguan 523808China Department of Materials Science and Engineering City University of Hong KongHong KongChina International Centre for Quantum and Molecular Structures Department of PhysicsShanghai UniversityShanghai 200444China Guangdong Provincial Engineering Technology Research Center for Low Carbon and Advanced Energy Materials Institute of Semiconductor Science and TechnologySouth China Normal UniversityGuangzhou 510631China

Rechargeable alkaline aqueous zinc batteries(RAZBs)have attracted increasing attention.However,most RAZBs are hindered by the limited availability of cathode materials.The practical electrochemical performance of most cathode materials is lower than the theoretical value due to their poor electrical conductivity and low utilization capacity.In this work,we develop a facile hydrothermal procedure to prepare highly uniform bimetallic sulfides as novel cathode materials for RAZBs.Copper-cobalt binary metallic oxides materials possess higher conductivity and larger capacity compared with their mono-metal oxides compounds due to bimetallic synergistic effects and multiple oxidation states.Furthermore,bimetallic sulfide compounds have smaller bond energy and longer bond length than their oxides,leading to less structural damage,faster kinetics of electrochemical reactions,and better stability.The as-prepared Co-Cu bimetallic sulfides show enhanced electrochemical performance due to various valences of Co and Cu as well as the existence of S.As a result,aqueous Zn/CuCo_(2)S_(4) battery shows a high specific capacity of 117.4 mAh/g at 4 A/g and a good cycle life of over 8000 cycles.Based on PANa hydrogel electrolytes,a flexible Zn/CuCo_(2)S_(4) battery demonstrates excellent cycling stability.This battery can also meet the requirements of electronic devices with different shapes and performs well in extreme environments,such as freezing,drilling,and hammering.This work opens new avenues to obtain high-rate and long-life cathode materials for RAZBs by utilizing the synergistic effects of bimetallic sulfides and provides a new platform for flexible energy storage devices.

关键词： Aqueous zinc batteries Bimetallic sulfides Cathode materials Rate performance Cycling stability

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Q＆P钢连续冷却过程的相变与组织研究

热加工工艺 2008年第4期37卷 39-41页

作者：李辉米振莉赵才江海涛赵松山北京科技大学高效轧制国家工程研究中心北京100083

在formastor热模拟试验机上研究了Q&P钢在不同连续冷却条件下的组织变化情况,用热膨胀法绘制了该钢的连续冷却转变曲线(CCT曲线)。用光镜对组织进行了观察,研究了Q&P钢的连续冷却转变过程及其对产物组织的影响。实验表明,随冷却速度的增... 详细信息

在formastor热模拟试验机上研究了Q&P钢在不同连续冷却条件下的组织变化情况,用热膨胀法绘制了该钢的连续冷却转变曲线(CCT曲线)。用光镜对组织进行了观察,研究了Q&P钢的连续冷却转变过程及其对产物组织的影响。实验表明,随冷却速度的增加,该钢铁素体、珠光体和贝氏体的相变开始温度和结束温度都趋于降低;只有当连续冷却速度在45℃/s左右时,才能抑制其他组织的析出,最终得到马氏体和残留奥氏体。该钢种CCT曲线的测定可以为新工艺的制定提供一定的参考依据。

关键词： Q&P钢热模拟连续冷却转变曲线组织

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Q＆P钢韧性断裂机制的实验研究

热加工工艺 2008年第20期37卷 18-20页

作者：赵才江海涛唐荻赵松山程知松北京科技大学高效轧制国家工程研究中心北京100083 太原科技大学材料科学与工程学院山西太原030024

采用扫描电镜(SEM)原位拉伸观察了Q&P钢退火组织断裂过程中裂纹萌生和扩展的动态变化过程,并对其微观断裂特征进行了研究。结果表明:加载初期,裂纹在与最大主应力平面成45°的位置萌生;加载中期,新的裂纹在主裂纹前方某处萌生,裂纹连接... 详细信息

采用扫描电镜(SEM)原位拉伸观察了Q&P钢退火组织断裂过程中裂纹萌生和扩展的动态变化过程,并对其微观断裂特征进行了研究。结果表明:加载初期,裂纹在与最大主应力平面成45°的位置萌生;加载中期,新的裂纹在主裂纹前方某处萌生,裂纹连接时伴随塑性变形;加载末期,裂纹失稳扩张,试样断裂。断口表面伴有韧窝的出现,呈延性断裂特征。

关键词： Q&P钢 SEM原位拉伸延长断裂