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Yield,etiologies and outcomes of capsule endoscopy in Thai patients with obscure gastrointestinal bleeding

World Journal of Gastrointestinal Endoscopy 2013年第3期5卷 122-127页

作者： Supot Pongprasobchai songla chitsaeng Tawesak Tanwandee Sathaporn Manatsathit Udom Kachintorn Division of Gastroenterology Department of Internal MedicineSiriraj HospitalMahidol UniversityBangkok 10700Thailand

AIM:To investigate the yield,etiologies and impact of capsule endoscopy(CE) in Thai patients with obscure gastrointestinal bleeding(OGIB).METHODS:The present study is a retrospective cohort *** patients with OGIB who underwent CE in Siriraj Hospital,Bangkok,Thailand during 2005-2009 were included in the *** the patients' medical records and results of the CE videos were *** findings were classified as significant,suspicious/equivocal and *** of the lesions were located to duodenum,jejunum,jejunoileum,ileum and diffuse lesions by the localization device of the *** of CE on the patients' management was defined by any investigation or treatment given to the patients that was more than an iron supplement or blood ***' outcomes(rebleeding,persistent bleeding,anemia or requirement of blood transfusion) were collected from chart reviews and direct phone interviews with the ***:Overall,there were 103 patients with OGIB included in the *** age of the patients was 64 ± 16 years(range 9-88 years) and 57 patients(55%) were *** of OGIB were overt in 80(78%) and occult in 23 patients(22%).The median time interval of CE after onset of OGIB was 10 d(range 1-180 d).The median time of follow-up was 19 mo(range 1-54 mo).Capsules reached caecum in 77 patients(74%) and capsule retention was found in 1 patient(1%).The diagnostic yield of CE revealed significant lesions in 37 patients(36%),suspicious/equivocal lesions in 15 patients(15%) and 51 patients(49%) had negative CE *** the significant lesions,the bleeding etiologies were small bowel ulcers in 44%,angiodysplasia in 27%,small bowel tumor in 13%,miscellaneous in 8% and active bleeding without identifiable causes in 8%.Patients with small bowel ulcers were significantly associated with the use of non-steroidal anti-inflammatory drugs(48%,P = 0.034),while patients with small bowel tumors were more commonly female(86%,P = 0.043) compared to the ot

关键词： Angiodysplasia Etiology Gastrointestinal Bleeding Obscure Capsule Endoscopy Outcome Small bowel ulcer Wireless

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