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Ralstonia solanacearum type Ⅲ effector RipAS associates with potato type one protein phosphatase StTOPP6 to promote bacterial wilt

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Horticulture Research 2023年第6期10卷 228-237页

作者： Bingsen Wang Wenfeng He Mengshu Huang Jiachen Feng Yanping Li Liu yu yuqi Wang Dan Zhou Chengzhen Meng Dong Cheng Ning Tang Botao song Huilan Chen National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Potato Biology and Biotechnology(HZAU) Ministry of Agriculture and Rural AffairsWuhan 430070China Potato Engineering and Technology Research Center of Hubei Province Huazhong Agricultural UniversityWuhan 430070China College of Horticulture and Forestry Science Huazhong Agricultural UniversityWuhan 430070China State Key Laboratory of Crop Stress Adaptation and Improvement Henan UniversityKaifeng 475001China

The bacterial pathogen Ralstonia solanacearum(***)delivered type III secretion effectors to inhibit the immune system and cause bacterial wilt on *** phosphatases are key regulators in plant immunity,which pathogens can manipulate to alter host ***,we show that a type III effector RipAS can reduce the nucleolar accumulation of a type one protein phosphatase(PP1)StTOPP6 to promote bacterial ***6 was used as bait in the Yeast two-Hybrid(Y2H)assay and acquired an effector RipAS that interacts with *** was characterized as a virulence effector to contribute to *** infection,and stable expression of RipAS in potato impaired plant resistance against *** of StTOPP6 showed enhanced disease symptoms when inoculated with wild strain UW551 but not the ripAS deletion mutant,indicating that the expression of StTOPP6 facilitates the virulence of *** reduced the nucleolar accumulation of StTOPP6,which occurred during *** ***,the association also widely existed between other PP1s and *** argue that RipAS is a virulence effector associated with PP1s to promote bacterial wilt.

关键词： impaired immunity TOP

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The Industrial Capital of the Chinese Traditional Culture - A Case Study of Li yu＇s Zhe School

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学术界 2015年第7期 264-268页

作者： song Xiaoli School of Digital Media Jiangnan University Wuxi Jiangsu 214122

It is the crucial for the development of cultural industry to transform cultural resources into cultural industry for which cultural creativity serves only as means,while cultural resources play the essential *** a result,exploring the Chinese traditional culture can promote the development of China' s cultural *** yu,the inheritor of the Zhe School integrates the spirit of the Zhe School into poetic drama and novels further realizing the social value of the Confucianism and *** Li yu with Lu Xun and Shao Yifu,we can see the capital value of the cultural industry of the Zhe *** the well-known "Li yu phenomenon" also provides a new horizon for researching upon the Chang' an School,the Hui School as well as the Zhe School today.

关键词：中国传统文化产业资本文化产业文化资源社会价值资本价值地平线学校

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Identifying the critical phosphorus balance for optimizing phosphorus input and regulating soil phosphorus effectiveness in a typical winter wheat-summer maize rotation system in North China

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Journal of Integrative Agriculture 2023年第12期22卷 3769-3782页

作者： XU Meng-ze WANG yu-hong NIE Cai-e song Gui-pei XIN Su-ning LU Yan-li BAI You-lu ZHANG Yin-jie WANG Lei State Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Key Laboratory of Plant Nutrition and Fertilizer of Ministry of Agriculture and Rural Affairs Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081P.R.China College of Resources and Environment Henan Agricultural UniversityZhengzhou 450002P.R.China

Phosphorus(P)is a nonrenewable resource and a critical element for plant growth that plays an important role in improving crop *** P fertilizer application is widespread in agricultural production,which not only wastes phosphate resources but also causes P accumulation and groundwater ***,we hypothesized that the apparent P balance of a crop system could be used as an indicator for identifying the critical P input in order to obtain a high yield with high phosphorus use efficiency(PUE).A 12-year field experiment with P fertilization rates of 0,45,90,135,180,and 225 kg P_(2)O_(5)ha^(-1)was conducted to determine the crop yield,PUE,and soil Olsen-P value response to P balance,and to optimize the P *** yield stagnation occurred when the P fertilizer application exceeded a certain level,and high yield and PUE levels were achieved with annual P fertilizer application rates of 90-135 kg P_(2)O_(5)ha^(-1).A critical P balance range of 2.15-4.45 kg P ha^(-1)was recommended to achieve optimum yield with minimal environmental *** critical P input range estimated from the P balance was 95.7-101 kg P_(2)O_(5)ha^(-1),which improved relative yield(>90%)and PUE(90.0-94.9%).In addition,the P input-output balance helps in assessing future changes in Olsen-P values,which increased by 4.07 mg kg^(-1)of P for every 100 kg of P ***,the P balance can be used as a critical indicator for P management in agriculture,providing a robust reference for limiting P excess and developing a more productive,efficient and environmentally friendly P fertilizer management strategy.

关键词： yield of winter wheat and summer maize phosphorus balance phosphorus use efficiency Olsen-P critical phosphorus application rate

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废物处理与管理信息化建设探讨与实践

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核动力工程 2013年第4期34卷 180-184页

作者：孔劲松余刃郭卫群项新民中国人民解放军92375部队海军工程大学海军核安全监督三站

探讨核动力系统废物处理与管理信息化建设的目标、内容和要求,以及在系统设计和开发过程中所遵循的一些思路和做法。结合某废物处理设施信息化建设的工程实践及建设过程中的一些关键问题,介绍信息系统的组成和体现结构。

关键词：核动力系统放射性废物处理信息管理系统

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Postprandial glucagon-like peptide 1 secretion is associated with urinary albumin excretion in newly diagnosed type 2 diabetes patients

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World Journal of Diabetes 2023年第3期14卷 279-289页

作者： Lu-Lu song Na Wang Jin-Ping Zhang Li-Ping yu Xiao-Ping Chen Bo Zhang Wen-Ying Yang Department of Endocrinology China-Japan Friendship HospitalBeijing 100029China

BACKGROUND Microalbuminuria is an early and informative marker of diabetic *** study found that microalbuminuria developed in patients with newly diagnosed type 2 diabetes mellitus(T2DM).AIM To investigate the association between glucagon-like peptide 1(GLP-1)and microalbuminuria in newly diagnosed T2DM *** In total,760 patients were recruited for this cross-sectional *** GLP-1 levels during a standard meal test and urinary albumin-creatinine ratio(UACR)were *** Patients with microalbuminuria exhibited lower GLP-1 levels at 30 min and 120 min during a standard meal test than patients with normal albuminuria(30 min GLP-1,16.7±13.3 pmol vs 19.9±15.6 pmol,P=0.007;120 min GLP-1,16.0±14.1 pmol vs 18.4±13.8 pmol,P=0.037).The corresponding area under the curve for active GLP-1(AUCGLP-1)was also lower in microalbuminuria patients(2257,1585 to 3506 vs 2896,1763 to 4726,pmol×min,P=0.003).Postprandial GLP-1 levels at 30 min and 120 min and AUCGLP-1 were negatively correlated with the UACR(r=0.159,r=0.132,r=0.206,respectively,P<0.001).The prevalence of microalbuminuria in patients with newly diagnosed T2DM was 21.7%,which decreased with increasing quartiles of AUCGLP-1 levels(27.4%,25.3%,18.9%and 15.8%).After logistic regression analysis adjusted for sex,age,hemoglobin A1c,body mass index,systolic blood pressure,estimated glomerular filtration rate,homeostasis model assessment of insulin resistance,AUC_(glucose)and AUC_(glucagon)patients in quartile 4 of the AUCGLP-1 presented a lower risk of microalbuminuria compared with the patients in quartile 1(odds ratio=0.547,95%confidence interval:0.325-0.920,P=0.01).A consistent association was also found between 30 min GLP-1 or 120 min GLP-1 and *** Postprandial GLP-1 levels were independently associated with microalbuminuria in newly diagnosed Chinese T2DM patients.

关键词： Microalbuminuria Glucagon-like peptide 1 Type 2 diabetes Nephropathy

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Association between Baseline SBP/DBP and All-Cause Mortality in Residents of Shanxi,China:A Population-based Cohort Study from 2002 to 2015

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Biomedical and Environmental Sciences 2021年第1期34卷 1-8页

作者： WANG Zhuo Qun ZHAI Yi LI Man YANG Xiu Feng ZHANG Jian REN Ze Ping ZHANG Mei song Peng Kun ZHAO Yan Fang MI Sheng Quan ZHANG Lu YANG Mao xiang ZHAO Wen Hua National Center for Chronic and Noncommunicable Disease Control and Prevention China CDCBeijing 100050China Beijing Tian tan Hospital Capital Medical UniversityChina National Clinical Research Center for Neurological DiseasesBeijing 100070China Hebei Key Laboratory of Environment and Human Health Department of Epidemiology and StatisticHebei Medical UniversityShijiazhuang 050017HebeiChina Xinfu Center for Disease Control and Prevention Xinfu 034000ShanxiChina National Institute for Nutrition and Health Chinese Center for Disease Control and PreventionBeijing 100050China Shanxi Center for Disease Control and Prevention Taiyuan 030012ShanxiChina College of Biochemical Engineering Beijing Union UniversityBeijing 100023China

Objective To investigate the association between blood pressure and all-cause mortality in Shanxi,*** The‘2002 China Nutrition and Health Survey’baseline data in Shanxi province was used.A retrospective investigation was performed in *** effects of SBP and DBP on the all-cause mortality were analyzed using the Cox regression *** hazard ratio(HR)and 95%confidence interval(CI)were estimated by the sex and age *** The follow-up rate was 76.52%over 13 years,while the cumulative mortality rate for all participants was 917.12/100,000 *** mortality rose with an increasing SBP(χ_(trend)^(2)=270.537,P60-year-old *** with DBP≥100 mm Hg had a significantly higher mortality,with an HR(95%CI)of 2.715(1.377–5.351).Conclusion Adults with SBP>160 mm Hg and DBP>100 mm Hg had a higher mortality *** and age difference was noted in both DBP and mortality risk.

关键词： Blood pressure Mortality Cohort study Hazard ratio Shanxi province

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The Observation of Martensite and Magnetic Domain Structures in Ni_(53)Mn_(24)Ga_(23) Shape Memory Alloys by Scanning Electron Acoustic Microscopy and Scanning Thermal Microscopy

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Chinese Physics Letters 2012年第5期29卷 70-73页

作者： ZHAO Kun-yu ZENG Hua-Rong song Hong-Zhang HUI Sen-Xing LI Guo-Rong YIN Qing-Rui Key Laboratory of Inorganic Functional Materials and Devices Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050 School of Physical Engineering and Material Physics Laboratory Zhengzhou UniversityZhengzhou 450052

We present observations of martensite variants and ferromagnetic domain structures of Ni_(53)Mn_(24)Ga_(23) ferromagnetic shape memory alloys with a pure tetragonal martensitic phase by using scanning electron aconstic microscopy (SEAM) and scanning thermal microscopy (SThM).Electron acoustic images show a polycrystalline morphology with martensite *** coincidence between crystallographic martensitic twin variants and magnetic domains is found.A domain-like structure,obtained by SThM,is firstly reported,and then confirmed by magnetic force microscopy (MFM).The experimental results will be helpful for investigating the local thermal properties of ferromagnets and understanding the relationship between martensite variants and magnetic domains.

关键词： martensite martensitic Electron

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Carbendazim induces a temporary change in soil bacterial community structure

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Journal of Environmental Sciences 2009年第12期21卷 1679-1683页

作者： WANG Xiuguo, song Min, GAO Chunming, DONG Bin, ZHANG Qun, FANG Hua, yu yunlong Department of Plant Protection, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China. [a] Department of Plant Protection College of Agriculture Biotechnology Zhejiang University Hangzhou 310029 China

The effect of carbendazim applications on the diversity and structure of a soil bacterial community was studied under field conditions using temperature gradient gel electrophoresis （TGGE） and partial sequence analysis of PCR-amplified 16S rRNA gene. After four successive introductions of carbendazim at a level of 0.94 kg active ingredient （a.i.）/ha, the genetic diversity （expressed as Shannon index, H′） decreased from 1.43 in the control to 1.29 in treated soil. This harmful effect seems to increase with the concentration of carbendazim. The value of H＇ in the soil treated with carbendazim at 4.70 kg a.i./ha was reduced to 1.05 （P ≤ 0.05）. The structure of soil bacterial community was also affected after four repeated applications of carbendazim at levels of 0.94, 1.88 and 4.70 kg a.i./ha, as seen in the relative intensities of the individual band. However, the bacterial community in carbendazim-treated soil recovered to that in the control 360 d after the first treatment. The results indicated that repeated applications of carbendazim could reduce soil microbial diversity and alter the bacterial community structure temporarily.

关键词： carbendazim bacterial diversity temperature gradient gel electrophoresis phylogenetic analysis

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一种基于差分进化的Flash文件系统垃圾回收算法

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电子学报 2011年第2期39卷 280-284页

作者：时正纪金松陈香兰龚育昌中国科学技术大学计算机系安徽合肥230027

垃圾回收算法对于Flash文件系统具有十分重要的意义.本文针对已有垃圾回收算法在存储容量剩余较小时垃圾回收性能急剧下降进而影响写入速率的问题,采用最优化方法,提出并实现了一种基于差分进化的垃圾回收算法.该算法能够使得垃圾回收... 详细信息

垃圾回收算法对于Flash文件系统具有十分重要的意义.本文针对已有垃圾回收算法在存储容量剩余较小时垃圾回收性能急剧下降进而影响写入速率的问题,采用最优化方法,提出并实现了一种基于差分进化的垃圾回收算法.该算法能够使得垃圾回收的代价均匀化,在保证性能和损耗均衡的前提下,减少擦除次数,延长Flash寿命.实验结果验证了该算法的有效性.

关键词：差分进化算法垃圾回收损耗均衡 Flash文件系统

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Can molecular ferroelectrics challenge pure inorganic ones?

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National Science Review 2014年第1期1卷 25-26页

作者： Zhe-Ming Wang song Gao Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering Peking University

Molecular materials have atracted much atention due to their advantages of easy modiication and fabrication,environmentally friendly and less energy-cost processing,transparent,light weight,mechanical lexibility and possible multi-functionalities,compared to their counter parts of pure inorganic or metallic ones,and many functionalities and properties have been discovered and realized in molecule-based materials[1–4].Ferroelectrics,as an important class of multifunctional

关键词： Can molecular ferroelectrics challenge pure inorganic ones high BTO

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