检索结果-南通市图书馆

Association of the HTR2C-759CT polymorphism and antipsychotic-induced weight gain:a meta-analysis

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General Psychiatry 2020年第3期33卷 118-126页

作者： Yan Chen Yewei Wang Xinyu Fang Yi Zhang lisheng song Chen Zhang Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Affiliated Shanghai Mental Health CenterShanghaiChina

Background Antipsychotic-induced weight gain(AIWG)is a crucial factor for the medication cessation of patients with *** studies have shown that the functional polymorphism-759 C/T(rs3813929)in the HTR2C promoter region could possibly be correlated with *** To evaluate the genetic association of the HTR2C-759C/T polymorphism and AIWG in patients with schizophrenia with antipsychotic drugs(APDs)*** Eligible studies were identified by searching the following databases:PubMed,Embase,Web of Science,China Nation Knowledge Infrastructure(CNKI),VIP,Wanfang Data,Chinese Biomedical Literature Database(CBM)and the Airiti *** quality of studies was evaluated based on the Newcastle-Ottawa *** pooled OR and 95%Cl were calculated for the dominant(CT/TT/T vs CC/C)mode,and subgroup analyses were performed based on ethnicity,antipsychotic medication and gender;ail statistical analyses were performed using the statistical software STATA *** A total of 17 studies with 3170 patients with schizophrenia were included in our *** result of the meta-analysis has shown that the association between the-759 C/T polymorphism and AIWG is statistically significant(OR 0.34,95%Cl:0.20 to 0.57,z=4.11,p<0.001).The subgroup analyses revealed significant correlations between the-759 C/T polymorphism and AIWG in the Caucasian population(OR 0.33,95%CI:0.14 to 0.77,z=2.55,p=0.011),the Asian population(OR 0.31,95%Cl:0.18 to 0.52,z=4.46,p<0.001),the patients with APDs administration(CT/JTfJ vs CC/C:OR 0.63,95%Cl:0.40 to 1.00,z=1.97,p=0.049)and the patients with atypical antipsychotic drug administration(CT/TT/T vs CC/C:OR 0.21,95%Cl:0.09 to 0.47,z=3.83,p<0.001).The sensitivity analysis showed that the results were ***'s test(after correction z=1.07,p=0.287)and Egger's test(t=-2.41,p=0.029)show that the included articles have no significant publication *** There is a significant genetic association between HTR

关键词： drugs analysis weight

Newly self-administered two-step tool for screening cognitive function in an ageing Chinese population:an exploratory cross-sectional study

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General Psychiatry 2023年第1期36卷 28-35页

作者： Jing Nie Yang Yang Yining Gao Wenwen Jiang Aisikeer Aidina Fei Sun Lucas R Prieto Jie Yu Kang Ju lisheng song Xia Li Department of Geriatric Psychiatry Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina School of Social Work Michigan State UniversityEast LansingMichiganUSA Department of Psychiatry Shanghai Changning Mental Health CenterShanghaiChina Department of Psychiatry Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina

Background Early screening of cognitive function is critical to dementia treatment and ***,traditional tests require face-to-face administration and are often limited by implementation costs and *** This study aimed to assess whether the Thoven Cognitive Self-Assessment(TCSA),a novel,innovative two-step touchscreen-based cognition assessment tool,could identify early cognitive impairment due to dementia in older *** The TCSA was administered to 61 healthy controls(HCs),46 participants with mild cognitive impairment(MCI)and 44 participants diagnosed with dementia recruited from *** outcome measures were generated from the TCSA test:the TCSA_(primary task)score and the TCSA_(secondary task)*** The total average scores in the control group for the TCSA_(primary task)and TCSA_(secondary task)were significantly higher than those in the MCI and dementia groups(TCSA_(primary task):HCs vs MCI group vs dementia group,8.58±1.76 vs 5.40±2.67 vs 2.74±2.11,F=75.40,p<0.001;TCSA_(secondary task):HCs vs MCI group vs dementia group,23.02±3.31 vs 17.95±4.93 vs 11.93±5.50,F=76.46,p<0.001).Moreover,receiver operating characteristic analysis showed that a score below 7.5 for the TCSA_(primary task)and a score below 22.5 for the TCSA_(secondary task)were indicators of *** The TCSA appears to be efficacious for the detection of cognitive impairment in older *** demonstrates the potential for large-scale cognition screening in community service settings.

关键词： function sectional cognitive

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哈佛大学的图书馆系统及馆藏管理

图书情报工作 2006年第2期50卷 131-134页

作者：宋力生北京大学图书馆北京100871

描述哈佛大学图书馆系统和馆藏管理的特点。哈佛大学图书馆通过开发不同类型的联合目录,有效管理和利用馆藏资源,并用一个现代化的共享式密集书库来解决馆藏空间不足的问题。另外,哈佛大学图书馆还采取分别协调、集中引进的方法对数字... 详细信息

描述哈佛大学图书馆系统和馆藏管理的特点。哈佛大学图书馆通过开发不同类型的联合目录,有效管理和利用馆藏资源,并用一个现代化的共享式密集书库来解决馆藏空间不足的问题。另外,哈佛大学图书馆还采取分别协调、集中引进的方法对数字化资源进行管理。

关键词：哈佛大学图书馆馆藏管理共享式密集书库

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网络环境下图书储藏模式的转变

大学图书馆学报 2006年第5期24卷 63-67页

作者：宋力生北京大学图书馆北京100871

近年来,由于藏书量的增长以及校园建筑空间有限、土地昂贵等原因,促使美国一些研究图书馆仿效哈佛大学图书仓库的模式,在远离校园的地方建设图书储藏库,储藏使用率低的文献,目前已建设了几十个这样的储藏库。储藏库通常为环境可控的、... 详细信息

近年来,由于藏书量的增长以及校园建筑空间有限、土地昂贵等原因,促使美国一些研究图书馆仿效哈佛大学图书仓库的模式,在远离校园的地方建设图书储藏库,储藏使用率低的文献,目前已建设了几十个这样的储藏库。储藏库通常为环境可控的、高度密集式排架的书库,有独立式的,有共享式或联盟式的。一些专业人士正在探讨把地方性图书馆和储藏库、区域性储藏库按照一定的系统或线索,例如地理区域线索,组成一个网络,为数字时代印刷型文献的保存和利用提供一个理想模式。

关键词：馆藏管理图书储藏模式密集书库国外

A Study on the Effect of Risperidone on PPI and P50 Deficit in FirstEpisode and Chronic Patients with Schizophrenia

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国际精神病学杂志 2016年第4期43卷 577-580页

作者： Lu Xu lisheng song Mingdao Zhang Xingshi Chen Rongqin Wu Jialin Tang Department of Psychiatry Shanghai zhabei Mental Health Center Shanghai 200436 China Neurophysiology Laboratory of Mental Health Center affiliated to School of Medicine of Shanghai Jiaotong University Shanghai 200030 China

Objective To investigate the effect of atypical antipsychotics risperidone on prepulse inhibition of the startle reflex(PPI) and P50 deficit in first-episode and chronic patients with schizophrenia. Methods PPI and P50 were tested and compared in 81 first-episode acute schizophrenia patients and 92 chronic schizophrenia patients before and after the risperidone. Results There was no significant difference in PPI and P50 indices between the two groups before treatment(P>0. 05); 2) there was no significant correlation between PPI & P50 inhibition indices and PANSS score, onset frequency and disease course(P>0.05); 3) Except the significant group main effect for S2 amplitude in P50(P=0. 02), there was no significant change for main effect and interaction of the other P50 and PPI inhibition ratio indices after treatment(P>0. 05). The effect of risperidone on PPI and P50 measurement index had nothing to do with the curative effect. Conclusion There exists a deficit in sensory gating inhibition in both first-episode schizophrenia and chronic schizophrenia, which is relatively independent from disease course. The risperidone is not effective in improving PPI and P50 inhibition deficit.

关键词： Schizophrenia Prepulse inhibition of the startle reflex P50 Risperidone

Research on the Balance of Urban Benchmark Land Price in Henan Province : A Case Study of Commercial Land

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Asian Agricultural Research 2021年第10期13卷 28-30,53页

作者： Yan TIAN lisheng song Ziwei WANG Lei WANG Xihui YANG Qingwei YANG Institute of Geography Henan Academy of SciencesZhengzhou 450052China Henan Kefa Geographic Research Institute Co. Ltd.Zhengzhou 450052China

The balance of benchmark land price is an important part of the work of urban benchmark land *** constructing different levels of factor layers,the balance of benchmark land price of urban commercial land in the urban areas of 18 provincial cities in Henan Province was *** urban areas were divided into 5 *** is found that the land price level in each urban area is basically consistent with the level of economic development,and the land price in some urban areas is low under the influnece of local policy.

关键词： Benchmark land price Balance Commercial land Henan Province

Differences in P50 and prepulse inhibition of the startle reflex between male smokers and non-smokers with first episode schizophrenia without medical treatment

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Chinese Medical Journal 2014年第9期127卷 1651-1655页

作者： song lisheng Chen Xingshi Chen Meijuan Tang Yunxiang Wang Jijun Zhang Mingdao Lou Feiying Liang Jianhua Chen Chong Department of Psychiatry Shanghai Mental Health Center Shanghai Jiao Tong University Shanghai 200030 China Department of Electrophysiology (Chen XS Zhang MD Lou FY Liang JH and Chen C) Department of EEG Source Imaging Shanghai Mental Health Center Shanghai Jiao Tong University Shanghai 200030 China

Backgorund Nicotine may improve schizophrenia patient＇s cognitive deficit *** study was to explore the chronic effects of smoking on prepulse inhibition of the startle reflex （PPI） and P50 in the patients with first-episode schizophrenia （FES）.Methods The event-related potentials （ERP） recording and analysis instrument made by Brain Products,Germany,was used to detect PPI and P50 in 49 male FES patients （FES group,n=21 for smokers and n=28 for non-smokers） and 43 normal male controls （control group,n=19 for smokers and n=24 for non-smokers）.Results Compared with normal controls,the FES group had prolonged PPI latency when elicited by single stronger stimulus （P ＜0.05）; the FES group had prolonged PPI latency and increased PPI amplitude （P ＜0.05,0.01） when elicited by weak and strong *** FES group had lower PPI inhibition rate than normal controls （P ＜0.05）.Compared with normal controls,the FES group had increased P50-S2 amplitude and increased amplitude ratio S2/S1 （both P ＜0.05）.In the control group,the smokers had a tendency of increase in P50-S2 amplitude （P ＞0.05） and shorter P50-S2 latency （P ＜0.05） than the *** smokers had higher PPI amplitude than the non-smokers （P ＜0.05）.In the FES group,the smokers had higher P50-S1 amplitude,shorter P50-S2 latency,and higher amplitude ratio S2/S1 than the non-smokers （P ＜0.05,0.01）.The smokers had higher PPI amplitude than the non-smokers （P ＜0.05）.Conclusions There is obvious PPI and P50 deficits in schizophrenic ***,these deficits are relatively preserved in the smokers compared with the non-smokers,which suggests that long-term smoking might partially improve the sensory gating in schizophrenic *** this conclusion can be deduced to female patients requires further follow-ups.

关键词： schizophrenia prepulse inhibition of the startle reflex P50 smoking

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SM8-KW型机织造假罗纹的工艺探讨

针织工业 2000年第4期 42-43页

作者：宋立胜烟台华隆电脑针织有限公司山东烟台265500

为满足广大消费者对立体感强、弹性大产品的需求,我公司开发设计了一系列假罗纹组织产品.目前已有多种此类产品投放市场,销售情况很好.现在我们共同探讨几种在SM8-KW型机上织造假罗纹的方法及工艺.经过几年的探索和实践,到目前为止,我们... 详细信息

为满足广大消费者对立体感强、弹性大产品的需求,我公司开发设计了一系列假罗纹组织产品.目前已有多种此类产品投放市场,销售情况很好.现在我们共同探讨几种在SM8-KW型机上织造假罗纹的方法及工艺.经过几年的探索和实践,到目前为止,我们在SM8-KW机上开发的假罗纹组织的产品有四种,工艺不同,作用也不同.

关键词：罗纹机针织罗纹组织工艺假罗纹

终极控制股东的政治关联、会计信息质量与注册会计师审计——来自民营上市公司的经验证据

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审计与经济研究 2014年第3期29卷 40-49页

作者：宋理升王爱国山东大学应用经济学博士后流动站山东济南250100 山东财经大学会计学院山东济南250014

以2008—2010年在沪、深证券交易所上市的民营上市公司为样本,研究发现终极控制股东的政治关联对会计信息质量具有显著的负面影响;无论终极控制股东的政治关联如何,注册会计师出具的审计报告类型与会计信息质量无显著相关关系;注册会计... 详细信息

以2008—2010年在沪、深证券交易所上市的民营上市公司为样本,研究发现终极控制股东的政治关联对会计信息质量具有显著的负面影响;无论终极控制股东的政治关联如何,注册会计师出具的审计报告类型与会计信息质量无显著相关关系;注册会计师收取的审计费用同会计信息质量显著负相关,终极控制股东政治关联的层次越高,该关系越显著。

关键词：终极控制股东政治关联会计信息质量审计费用审计意见盈余质量审计报告