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Novel Method for Evaluating the Aging of Aviation Turbine Engine Oils via High-Temperature Bearing Deposit Tests

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China Petroleum Processing & Petrochemical Technology 2024年第1期26卷 67-77页

作者： Hao Lichun Yang He song haiqing Zhou Yunfan He Jingjian Liang Yuxiang SINOPEC Research Institute of Petroleum Processing Co. Ltd.Beijing 100083

Aviation turbine engine oils require excellent thermal-oxidative stability because of their high-temperature ***-temperature bearing deposit testing is a mandatory method for measuring the thermal-oxidative performance of aviation lubricant oils,and the relevant apparatus was improved in the present *** different commercial aviation turbine engine oils were tested,one with standard performance(known as the SL oil)and the other with high thermal stability,and their thermal-oxidative stability characteristics were *** 100 h of high-temperature bearing testing,the SL oil was analyzed by using various analytical techniques to investigate its thermal-oxidative process in the bearing test,with its thermal-oxidative degradation mechanism also being *** results indicate that the developed high-temperature bearing apparatus easily meets the test requirements of method 3410.1 in standard *** viscosity and total acid number(TAN)of the SL oil increased with the bearing test time,and various deposits were produced in the bearing test,with the micro-particles of the carbon deposits being sphere-like,rod-like,and sheet-like in *** antioxidant additives in the oil were consumed very rapidly in the first 30 h of the bearing test,with N-phenyl-1-naphthylamine being consumed faster than ***,the oil thermal-oxidative process involves very complex physical and chemical mechanisms.

关键词： aviation turbine engine oil high-temperature bearing deposit test thermal-oxidative degradation antioxidant additives

Constant Volume Spray Auto-ignition Study of Alkanes

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China Petroleum Processing & Petrochemical Technology 2019年第1期21卷 71-79页

作者： Wang Jun Yang He song haiqing Tian Huayu Wang Pengfei SINOPEC Research Institute of Petroleum Processing

Spray auto-ignition experiments were carried out in a constant volume combustion chamber for some pure alkanes(n-paraffins with different chain length, cyclohexane, n-butyl cyclohexane, and isooctane) and blends of n-decane with Standard Blended Fuel(isooctane/n-heptane) and product gasoline. Test results showed that the reaction activity of n-paraffins was relatively high. Meanwhile, the auto-ignition characteristics differed significantly with the molecular structures of alkanes. Adding different volume fractions of n-decane to Standard Blended Fuel and product gasoline could improve the fuel reaction activity at varying degree. Finally, functional groups effects were used to simulate the relationship between the molecular topology and the auto-ignition quality.

关键词： spray auto-ignition reaction activity functional group alkane

Study on Tribology Performance of Different Lubricant Additives under Atmospheric Pressure and High Vacuum Conditions

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China Petroleum Processing & Petrochemical Technology 2016年第4期18卷 81-91页

作者： Peng Qian Huang Zhiyang Yang He song haiqing Zhang Jianrong Research Institute of Petroleum Processing SINOPEC

By using PAO-10 as the base oil, the tribological behavior of 11 additives under high vacuum condition was evaluated. By adopting some surface analytical instruments, such as scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS) and X-ray photoelectron spectroscopy(XPS), the tribological mechanisms of these additives were studied. In air, O_2 can react with metal to form metal oxide that can protect the surfaces of rubbing pair during the tribological tests. According to the theory of the competitive adsorption, the function of some active elements is weakened. In a vacuum environment, the additives contributed more to the lubrication performance. The sulfur-containing additives could react with Fe to produce Fe Sx and "M—C" bonds("M" represents metal). They both had contributions to the lubrication. As for the phosphorus-containing additives, they only generated the phosphates during the tests. When the sulfur and phosphorus-containing additives were applied, the generated phosphates and Fe Sx had the primary contribution to the lubrication performance during the tests.

关键词： anti-wear additive high vacuum lubrication mechanism anti-wear properties friction reducing properties

Influence of Ethanol Addition on the Spray Auto-ignition Properties of Gasoline and Its Relationship with Octane Number

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China Petroleum Processing & Petrochemical Technology 2022年第2期24卷 68-75页

作者： Wang Jun Yang He Hu Xiaoming song haiqing Zhang Ran Tian Huayu SINOPEC Research Institute of Petroleum Processing Beijing 100083

In this study,the spray auto-ignition properties of binary primary reference fuels(PRFs)of 2,2,4-trimethylpentane and n-heptane with different research octane numbers(RONs)were measured according to the industry standard NB/SH/T 6035 to determine their ignition delay times at various initial ***,the auto-ignition properties were investigated after blending the PRFs with various amounts of *** results revealed a very good correlation between the derived cetane number and the RON for the PRFs in both the presence and absence of *** addition,a concept of ignition delay sensitivity was developed for ethanol-containing fuels that exhibited a close relationship with the octane sensitivity,which is defined as the RON minus the motor octane number(MON).Finally,the developed method was applied to conveniently estimate the RON and MON values of several ethanol-containing fuels by simply measuring their auto-ignition properties.

关键词： ethanol spray auto-ignition ignition delay octane number sensitivity

Evaluation of the Oxidation Reactivity and Behavior of Exhaust Soot Particles from Diesel Engines with Different Emission Levels

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China Petroleum Processing & Petrochemical Technology 2024年第2期26卷 72-80页

作者： Wang Yajun Lin Lei Xing Jianqiang LüXu Yang He song haiqing SINOPEC Research Institute of Petroleum Processing Co. Ltd.Beijing 100083China State Key Laboratory of Engines Tianjin UniversityTianjin 300072China

The aim of this study was to investigate the oxidation reactivity and behavior of exhaust particulate matter(PM)from diesel *** samples from two diesel engines(1K,CY4102)with different emission levels were collected by a thermophoretic system and a quartz *** oxidation reactivity,oxidation behaviors,and physicochemical properties of the PM samples were analyzed using thermogravimetric analysis(TGA),high-resolution transmission electron microscopy(HRTEM),Fourier-transform infrared spectrometry(FTIR),and Raman *** results showed that there was a great difference in the oxidation reactivity of soot particles emitted by the two different diesel engines.A qualitative analysis of the factors influencing oxidation reactivity showed that the nanostructure,degree of graphitization,and relative concentration of aliphatic C—H functional groups were the most important factors,whereas no significant correlation was found between the primary particle size and activation energy of the diesel *** on the oxidation behavior analysis,the diesel soot particles exhibited both internal and surface oxidation modes during the oxidation *** oxidation was dominant during the initial stage,and as oxidation progressed,the mode gradually changed to internal *** oxidation mode of soot particles from the 1K engine was significantly higher than that of CY4102.

关键词： diesel engine soot particles oxidation reactivity oxidation behavior

Disruption of cyclin D1 degradation leads to the development of mantle cell lymphoma

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Acta Pharmaceutica Sinica B 2024年第7期14卷 2977-2991页

作者： Ke Lu Ming Zhang Hongyu Qin Siyu Shen haiqing song Hua Jiang Chunxiang Zhang Guozhi Xiao Liping Tong Qing Jiang Di Chen Research Center for Computer-aided Drug Discovery Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Faculty of Pharmaceutical Sciences Shenzhen Institute of Advanced TechnologyShenzhen 518055China Oncology Department Johns Hopkins University School of MedicineBaltimoreMD 21205USA Division of Spine Surgery the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Division of Sports Medicine and Adult Reconstructive Surgery Department of Orthopedic SurgeryNanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolState Key Laboratory of Pharmaceutical BiotechnologyNanjing UniversityNanjing 210008China Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China Department of Cardiology Basic Medicine Innovation Center for Cardiometabolic Diseases of Ministry of EducationInstitute of Cardiovascular Researchthe Affiliated HospitalSouthwest Medical UniversityLuzhou 646000China School of Medicine Southern University of Science and TechnologyShenzhen 518055China

Cyclin D1 has been recognized as an oncogene due to its abnormal upregulation in different types of ***,we demonstrated that cyclin D1 is SUMOylated,and we identified Itch as a specific E3 ligase recognizing SUMOylated cyclin D1 and mediating SUMO-induced ubiquitination and proteasome degradation of cyclin *** generated cyclin D1 mutant mice with mutations in the SUMOylation site,phosphorylation site,or both sites of cyclin D1,and found that double mutant mice developed a Mantle cell lymphoma(MCL)-like *** showed that arsenic trioxide(ATO)enhances cyclin D1 SUMOylation-mediated degradation through inhibition of cyclin D1 deSUMOylation enzymes,leading to MCL cell *** of severe combined immunodeficiency(SCID)mice grafted with MCL cells with ATO resulted in a significant reduction in tumor *** this study,we provide novel insights into the mechanisms of MCL tumor development and cyclin D1 regulation and discover a new strategy for MCL treatment.

关键词： Cyclin D1 SUMOylation Mantle cell lymphoma Arsenic trioxide SENP2 Proteasome degradation

Evaluation of the Adaptability of Six Sets of Precipitation Data in Inner Mongolia

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Meteorological and Environmental Research 2021年第5期12卷 21-30,34页

作者： Yan HUANG haiqing song Xiaolong SUN Shiyun LIU Ulanqab Meteorological Bureau Ulanqab 012000China Ecological and Agricultural Meteorology Center of Inner Mongolia Autonomous Region Hohhot 010051China

Based on daily precipitation data of 119 weather stations over Inner Mongolia in 2018,the adaptability of six sets of precipitation data( GLDAS2.1,ITPCAS,CLDAS2.0,CMPAS2.0 ERA5 and CMPAS2.1) in Inner Mongolia was evaluated and analyzed by using Pearson correlation coefficient( R),mean deviation( Bias) and root mean square error( RMSE).The results indicate that the six sets of precipitation data could well reflect the spatial and temporal variation of precipitation over Inner *** a ten-day scale,the mean deviation of CMPAS2.1 had a smaller variation,which slightly underestimated precipitation;the mean deviation of CLDAS2.0 had a smaller variation in the eastern region;the mean deviation of both ITPCAS and CMPAS2.0 was more stable in the central region than in the eastern and western regions;the mean deviation of GLDAS2.1 and ERA5 had a relatively larger variation,and ERA5 overestimated precipitation to a certain extent;the root mean square error of CMPAS2.1 had the smallest variation,whereas that of ERA5 was relatively *** monthly scale was similar to the ten-day *** correlation coefficient of the six sets of precipitation data in the central region was better than that in the east and west,and the mean deviation and root mean square error were relatively larger in areas with more complex mountain *** to statistical indicators,CMPAS2.1 performed better in Inner Mongolia than other five sets of data.

关键词： Precipitation data Inner Mongolia Evaluation

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基于拉丁超方抽样的全渠道供应链网络优化

系统工程理论与实践 2019年第7期39卷 1704-1713页

作者：张思敏宋海清中山大学岭南学院

全渠道零售模式下需求的大样本、差异性、相关性特征将改变传统供应链的网络结构,文章构建离散拉丁超方抽样的免疫遗传算法进行全渠道供应链网络优化.先通过离散拉丁超方抽样对需求数据进行处理,保留样本特征的基础上减少样本容量,然后... 详细信息

全渠道零售模式下需求的大样本、差异性、相关性特征将改变传统供应链的网络结构,文章构建离散拉丁超方抽样的免疫遗传算法进行全渠道供应链网络优化.先通过离散拉丁超方抽样对需求数据进行处理,保留样本特征的基础上减少样本容量,然后通过免疫遗传算法进行供应链网络多目标多机制优化,在保证较快收敛的同时避免局部极值,以此解决全渠道零售模式下供应链网络优化问题.实例证明该模型与算法的有效性以及在实践中的可行性.

关键词：全渠道零售供应链网络辐射范围离散拉丁超方抽样免疫遗传算法

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世界患者安全日谈药源性神经系统疾病

药物不良反应杂志 2022年第9期24卷 449-453页

作者：宋海庆首都医科大学宣武医院神经内科北京100053

2022年世界患者安全日的主题是"用药安全"。用药安全已成为当今生命科学研究领域的热点问题,药物对中枢神经系统的不良影响也逐渐引起临床重视。常见的药源性神经系统疾病有药源性癫痫、药源性锥体外系疾病、药源性脑病、药源性卒中、... 详细信息

2022年世界患者安全日的主题是"用药安全"。用药安全已成为当今生命科学研究领域的热点问题,药物对中枢神经系统的不良影响也逐渐引起临床重视。常见的药源性神经系统疾病有药源性癫痫、药源性锥体外系疾病、药源性脑病、药源性卒中、药源性视觉障碍、药源性脊髓损伤、药源性睡眠障碍、药源性认知功能障碍、药源性5-羟色胺综合征及药源性周围神经病等。引起药源性神经系统疾病的药物主要包括抗精神病药物、抗焦虑和抑郁类药物、抗惊厥药物、肿瘤化疗药物以及一些治疗心血管系统疾病的药物如他汀类等。对疑似药源性神经系统疾病的处理原则包括(1)完善检查,明确诊断;(2)消除病因,停用或减量应用致病药物;(3)清除体内致病药物;(4)对症治疗,营养支持。

关键词：药物相关副作用和不良反应神经系统用药错误患者安全