检索结果-南通市图书馆

Association of COVID-19 with hepatic metabolic dysfunction

World Journal of Virology 2022年第5期11卷 237-251页

作者： Ramesh Kumar Vijay Kumar Rahul arya Utpal Anand Rajeev Nayan Priyadarshi Department of Gastroenterology All India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Medicine All India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Surgical Gastroenterology All India Institute of Medical SciencesPatnaPatna 801507BiharIndia Department of Radiodiagnosis All India Institute of Medical SciencesPatnaPatna 801507BiharIndia

The coronavirus disease 2019(COVID-19)pandemic continues to be a global problem with over 438 million cases reported so *** it mostly affects the respiratory system,the involvement of extrapulmonary organs,including the liver,is not *** the beginning of the pandemic,metabolic comorbidities,such as obesity,diabetes,hypertension,and dyslipidemia,have been identified as poor prognostic *** metabolic and lipidomic studies have identified several metabolic dysfunctions in patients with *** metabolic alterations appear to be linked to the course of the disease and inflammatory reaction in the *** liver is an important organ with high metabolic activity,and a significant proportion of COVID-19 patients have metabolic comorbidities;thus,this factor could play a key role in orchestrating systemic metabolic changes during *** suggests that metabolic dysregulation in COVID-19 has both short-and long-term metabolic ***,COVID-19 has adverse associations with metabolic-associated fatty liver *** to the ensuing effects on the renin-angiotensin-aldosterone system and ammonia metabolism,COVID-19 can have significant implications in patients with advanced chronic liver disease.A thorough understanding of COVID-19-associated metabolic dysfunction could lead to the identification of important plasma biomarkers and novel treatment *** this review,we discuss the current understanding of metabolic dysfunction in COVID-19,focusing on the liver and exploring the underlying mechanistic pathogenesis and clinical implications.

关键词： COVID-19 Coronavirus Metabolism Metabolic syndrome Metabolic inflammation Hepatic dysfunction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Developing a Computer Program for Detailed Study of Planing Hull＇s Spray Based on Morabito＇s Approach

引用

Journal of Marine Science and Application 2014年第4期13卷 402-415页

作者： Parviz Ghadimi Sasan Tavakoli Abbas Dashtimanesh arya Pirooz Department of Marine Technology Amirkabir University of Technology Tehran 15875-4413 Iran Faculty of Engineering Persian Gulf University Bushehr *** Iran International Branch Amirkabir University of Technology Tehran 15875-4413 Iran

Recently, Morabito(2010) has studied the water spray phenomena in planing hulls and presented new analytical equations. However, these equations have not been used for detailed parametric studies of water spray around planing hulls. In this paper, a straight forward analysis is conducted to apply these analytical equations for finding the spray geometry profile by developing a computer program based on presented computational process. The obtained results of the developed computer program are compared against existing data in the literature and favorable accuracy is achieved. Parametric studies have been conducted for different physical parameters. Positions of spray apex are computed and three dimensional profiles of spray are examined. It is concluded that spray height increases by an increase in the speed coefficient or the deadrise angle. Ultimately, a computational process is added to Savitsky's method and variations of spray apex are computed for different velocities. It is shown that vertical, lateral, and longitudinal positions of spray increase as the craft speed increases. On the other hand, two new angles are defined in top view and it is concluded that they have direct relation with the trim angle. However, they show inverse relation with the deadrise angle.

关键词：计算机程序研究开发喷雾速度系数计算过程三维轮廓位置计算喷射高度

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A review on melatonin action as therapeutic agent in cancer

引用

Frontiers in Biology 2018年第3期13卷 180-189页

作者： Soumya Nair Sandra Suresh arya Kaniyassery Panchami Jaya Jayanthi Abraham Microbial Biotechnology Laboratory School of Biosciences and Technology VIT University Vellore Tamil Nadu India

Melatonin is a hormone which is produced from pineal gland in human and is said to have various impacts in human body like controlling sleep wake cycle, regulating the immune and cardiovascular system and regulating the peripheral organ functioning to name a few. Researchers have reported that the melatonin levels correlates with cancer risks. In this review article, focus has been given to the therapeutic applications and impact of melatonin hormone in human behavior and physiologic activities. Through this article we aim in compiling the scattered information regarding melatonin and its various aspects of importance in human system. We made an analysis of existing hypothesis and studies published on melatonin and circadian rhythm, factors effecting Melatonin secretions in body, sleep disturbances and cancer risks and melatonin therapy in cancer patients. Melatonin’s role as an endogenous synchronizer, growing evidence suggests its anti-oxidative activity as well as its having a role in modulating immune responses. Fluctuating melatonin levels can be boosted by ingesting products containing melatonin. A large portion of the examinations detailed by the researchers clearly conclude that keeping up an impeccable sleep-wake cycle and having a healthy diet is extremely important to keep up the regular melatonin levels and in order to stay fit. Melatonin is considered as a critical hormone that controls and regulates many functions in our body. Melatonin production is emphatically related to the night time duration. Its most absolute biological role is to convey information to the body about day length for a variety of physiologic functions. In addition to melatonin’s role as an endogenous synchronizer, growing evidence suggests its anti-oxidative activity as well as its having a role in modulating immune responses. At present, a growing interest is focused on the validity of the anti-tumor mechanisms of melatonin.

关键词： Melatonin, circadian rhythm, breast cancer, pineal gland, melatonin therapy, peripheral organ functioning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neurological manifestations of hepatitis E virus infection:An overview

引用

World Journal of Gastroenterology 2021年第18期27卷 2090-2104页

作者： Ashish Kumar Jha Gaurav Kumar Vishwa Mohan Dayal Abhay Ranjan arya Suchismita Department of Gastroenterology Indira Gandhi Institute of Medical SciencesPatna 800014India Department of Neurology Indira Gandhi Institute of Medical SciencesPatna 800014India Department of Pediatric Hepatology Institute of Liver and Biliary SciencesBasant Kunj 110070New DelhiIndia

Hepatitis E virus(HEV)is an important cause of repeated waterborne outbreaks of acute ***,several extrahepatic manifestations(EHMs)have been described in patients with HEV *** these,neurological disorders are the most common EHM associated with *** involvement of both the peripheral nervous system and central nervous system can occur together or in *** can present with normal liver function tests,which can often be misleading for *** is a paucity of data on HEV-related neurological manifestations;and these data are mostly described as case reports and case *** this review,we analyzed data of 163 reported cases of HEV-related neurological *** mechanisms of pathogenesis,clinico-demographic profile,and outcomes of the HEV-related neurological disorders are described in this *** root and plexus disorder were found to be the most commonly reported disease,followed by meningoencephalitis.

关键词： Hepatitis E virus Acute hepatitis E Extrahepatic manifestations Neurological manifestations Neuralgic amyotrophy Guillain-Barrésyndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microscopic and metabolic investigations disclose the factors that lead to skin cracking in chili-type pepper fruit varieties

引用

Horticulture Research 2023年第4期10卷 211-224页

作者： Ofir Marinov Gal Nomberg Sutanni Sarkar Gulab Chand arya Eldad Karavani Einat Zelinger Ekaterina Manasherova Hagai Cohen Department of Vegetable and Field Crops Institute of Plant SciencesAgricultural Research Organization(ARO)Volcani InstituteRishon LeZion 7505101Israel Department of Plant Pathology and Microbiology The Robert H.Smith Faculty of AgricultureFood and EnvironmentThe Hebrew University of JerusalemRehovot 7610001Israel Center for Scientific Imaging(CSI) The Robert H.Smith Faculty of AgricultureFood and EnvironmentThe Hebrew University of JerusalemRehovot 7610001Israel

The hydrophobic cuticle encasing the fruit skin surface plays critical roles during fruit development and *** failure often results in the fruit surface cracking and forming a wound-periderm tissue made of suberin and *** factors that make the fruit skin susceptible to cracking have yet to be fully ***,we investigated two varieties of chili peppers(Capsicum annuum L.),Numex Garnet,whose fruit has intact skin,and Vezena Slatka,whose fruit has cracked *** observations,gas chromatography-mass spectrometry,biochemical and gene expression assays revealed that Vezena Slatka fruit form a thicker cuticle with greater levels of cutin monomers and hydroxycinnamic acids,and highly express key cutin-related *** skin of these fruit also had a lower epidermal cell density due to cells with very large perimeters,and highly express genes involved in epidermal cell *** demonstrate that skin cracking in the Vezena Slatka fruit is accompanied by a spatial accumulation of lignin-like polyphenolic compounds,without the formation of a typical wound-periderm tissues made of suberized ***,we establish that skin cracking in chili-type pepper significantly affects fruit quality during post-harvest storage in a temperature-dependent *** conclusion,our data highlight cuticle thickness and epidermal cell density as two critical factors determining fruit skin susceptibility to cracking in chili-type pepper fruit.

关键词： varieties pepper cracking

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Species limits in the Elegant Pitta (Pitta elegans) complex from Wallacea based on bioacoustic and morphometric analysis

引用

Avian Research 2020年第4期11卷 421-432页

作者： arya Y.Yue Elize Y.X.Ng James A.Eaton Frank E.Rheindt Bryn Mawr College Department of Biology101 N Merion AveBryn MawrPA 19010USA Department of Biological Sciences National University of Singapore16 Science Drive 4Singapore 117558Singapore A-3A-5 Casa Indah IPersiaran Surian47810 Petaling JayaMalaysia

Background:The Elegant Pitta(Pitta elegans)complex displays a remarkable diversity of morphological and bioacoustic traits across five taxa currently recognized as *** differ in plumage characteristics(such as red versus black belly patches;supercilium color and extent;and white versus black throats),in lifestyle(resident versus migratory)and in *** investigated the morphological,bioacoustic and ecological differences across all taxa after recent studies demostrated the importance of these traits in recognizing biological species limits across ***:Morphometric analysis was carried out by measuring tarsus,wing,tail and bill lengths of 15 specimens at the Natural History Museum,UK,and plumages were inspected across 106 unique individuals from four different *** analysis was based on 134 range-wide sound *** types of calls,territorial calls and alarm calls,were analyzed using different sets of *** component analysis and the Isler Criterion were applied to the *** trials were conducted to explore the levels of response of each taxon to the call types of the other ***:The territorial call of concinna exhibits a distinct two-element motif,while elegans,maria and virginalis utter a three-element motif in which the first two elements are given in quick *** the other hand,vigorsii,produces both two-element and three-element motifs with longer breaks in between *** further corroborated by the playback trials,the three taxa elegans,virginalis and maria form a tight vocal cluster,whereas each concinna and vigorsii are *** alarm call turned out to be less diagnostic even though most taxa did roughly separate into different vocal *** analysis failed to produce strong differences,but plumage distinctions among multiple taxa are ***:We suggest splitting the Elegant Pitta into three biological species based on

关键词： Bioacoustic analysis Elegant Pitta Morphometric analysis Pitta elegans Territorial calls

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Performance index improvement of a double-pipe cooler with MgO/water-ethylene glycol (50:50) nano-suspension

引用

Propulsion and Power Research 2020年第1期9卷 75-86页

作者： H.arya M.M.Sarafraz O.Pourmehran M.Arjomandi Centre for Energy Resource Engineering Technical University of DenmarkDenmark School of Mechanical Engineering University of AdelaideSouth AustraliaAustralia

A series of tests was conducted to unlock the potential application of MgO/water-EG(ethylene glycol)nanofluids(NF)in a double-pipe heat exchanger(HEX).The overall heat transfer coefficient(HTC),the inlet temperature of the working fluid,the fluid pressure drop(FPD),friction factor(FF)and the hydraulic performance index of the NF within the HEX were experimentally *** of nanoparticles(NPs)within the Hex was also studied and modelled using asymptotic particulate fouling *** showed that MgO NPs can enhance the HTC by 39%at Re=10500 and wt.%=0.3 in the turbulent ***,the presence of MgO NPs augmented the FF and the FPD *** former was enhanced 33.8%,while the latter was augmented by 37%both at wt.%=0.3 and at Reynolds number=*** also revealed that the formation of porous particulate fouling layer on the internal wall of the inner tube creates a fouling thermal resistance which changes asymptotically with ***,MgO/water-ethylene glycol shows a great potential to be used as a coolant within a HEX.

关键词： Forced convective heat transfer Particulate fouling Heat exchanger Fouling Nanofluid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tubercular arthritis of the elbow joint following olecranon fracture fixation and the role of TGF-beta in its pathogenesis

引用

Chinese Journal of Traumatology 2013年第5期16卷 288-291页

作者： Masood Habib Yashwant Singh Tanwar Atin Jaiswal Rajender Kumar arya Department of Orthopedic Surgery PGIMER & Dr R.M.L Hospital New Delhi India 11001

在起始的骨折的时候没有 TB 的历史和 TB 感染的没有证据在病人发生在关上的骨头破裂以后的肺结核(TB ) 是一个稀罕实体。我们报导与开的 olecranon 破裂在紧急情况部门介绍了的 48 岁的女性的一个如此的案例与紧张乐队配线减少了并且... 详细信息

在起始的骨折的时候没有 TB 的历史和 TB 感染的没有证据在病人发生在关上的骨头破裂以后的肺结核(TB ) 是一个稀罕实体。我们报导与开的 olecranon 破裂在紧急情况部门介绍了的 48 岁的女性的一个如此的案例与紧张乐队配线减少了并且内部修理了。在外科以后在 3 个星期与 serosanguineous 分泌物在门诊病人部门介绍的病人。分泌物被去请文化和敏感测试，和病人被抗菌素和每日的调味品管理。有裂开并且位于下面植入的创伤被暴露，它在外科以后在 12 个星期被移开。继续 6 个月的重复清创术和调味品，而是从创伤地点的分泌物继续。在 6 个月执行的肘的 X 光提起了 TB 的怀疑，它被 Ziel-Neelsen 染色和清除织物的组织病理学说的检查证实。跟随证实，病人被放在 antitubercular 药上。病人对 antitubercular 药治疗(ATT ) 作出回应，从创伤的化脓的分泌物停止了，并且最后，创伤在 2 月开始 ATT 以后愈合了。

关键词：骨折内固定结核病肘关节 TGF-β 病理组织学检查关节炎发病抗结核药物

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Choriocapillaris changes in dry age-related macular degeneration and geographic atrophy: a review

引用

Eye and Vision 2018年第1期5卷 204-210页

作者： Malvika arya Almyr S.Sabrosa Jay S.Duker Nadia K.Waheed New England Eye Center Tufts Medical CenterBostonMAUSA Institude of Ophthalmology Rio de JaneiroBrazil

Age-related macular degeneration(AMD)is a leading cause of central vision loss *** progression of dry AMD from early to intermediate stages is primarily characterized by increasing drusen formation and adverse impact on outer retinal *** stage AMD consists of either geographic atrophy(GA),the non-exudative(dry)AMD subtype,or choroidal neovascularization,the exudative(wet)AMD *** is characterized by outer retinal and choroidal atrophy,specifically the photoreceptor layer,RPE,and *** remains to be discovered regarding the pathogenesis of AMD progression and subsequent development of *** the functionality of all three layers is closely linked,the temporal sequence of events that end up in atrophy is important in the understanding of the pathogenic pathway of the *** advent of OCTA,and particularly of swept-source technology,has allowed for depth-resolved imaging of retinal vasculature and the *** the use of OCTA,recent studies demonstrate that choriocapillaris flow alterations are closely associated with the development and progression of *** changes may even possibly offer predictive value in determining progression of *** article reviews studies demonstrating choriocapillaris changes in dry AMD and summarizes the existing literature on the potential role of the choriocapillaris as a key factor in the pathogenesis of AMD.

关键词： Dry age-related macular degeneration Geographic atrophy Choriocapillaris Optical coherence tomography Optical coherence tomography angiography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Torsion of spleen and portal hypertension: Pathophysiology and clinical implications

引用

World Journal of Hepatology 2021年第7期13卷 774-780页

作者： Ashish Kumar Jha Sameer Bhagwat Vishwa Mohan Dayal arya Suchismita Department of Gastroenterology Indira Gandhi Institute of Medical SciencesPatna 800014India Department of Paediatric Hepatology Institute of Liver and Biliary SciencesDelhi 110070India

The displacement of spleen from its normal location to other places is known as wandering spleen(WS)and is a rare *** repeated torsion of WS is due to the presence of long pedicle and absence/laxity of anchoring ligaments.A WS is an extremely rare cause of left-sided portal hypertension(PHT)and severe gastric variceal ***-sided PHT usually occurs as a result of splenic vein occlusion caused by splenic torsion,extrinsic compression of the splenic pedicle by enlarged spleen,and splenic vein *** is a paucity of data on WSrelated PHT,and these data are mostly in the form of case *** this review,we have analyzed the data of 20 reported cases of WS-related *** mechanisms of pathogenesis,clinico-demographic profile,and clinical implications are described in this *** majority of patients were diagnosed in the second to third decade of life(mean age:26 years),with a strong female preponderance(M:F=1:9).Eleven of the 20 WS patients with left-sided PHT presented with abdominal pain and *** 6 of the 11 patients,varices were detected incidentally on preoperative imaging studies or discovered ***,pre-operative search for varices is required in patients with splenic torsion.

关键词： Wandering spleen Splenic torsion Left-sided portal hypertension Gastric variceal bleeding Splenectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：