检索结果-南通市图书馆

The Effect of Antineoplas.ons.A10 and As.-1 and metabolites.of s.dium Phenylbutyrate on Gene Expres.ion in Glioblas.oma multiforme

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2014年第10期5卷 929-945页

作者： s.anis.aw R. Burzyns.i sonali s. Patil Department of Cell and molecular Biology Burzynski Research Institute Inc. Stafford TX USA

Antineoplas.ons.are peptide and amino acid derivatives.that occur naturally in the human body. They inhibit the growth of neoplas.ic cells.without growth inhibition of normal cells. Phenylacetylglutaminate (PG) is.an active ingredient of antineoplas.ons.A10 and As.-1 (ANP) and is.als. a metabolic by-product of phenylbutyrate (PB). The formulation of antineoplas.on As.-1 is.a 4:1 mixture of phenylacetate (PN) and PG. Antineoplas.on A10 is.a 4:1 mixture of PG and is.PG. This.s.udy inves.igates.the molecular mechanis. of action of PG and PN. The Human U87 glioblas.oma (GBm) cell line was.us.d as.the model s.s.em in this.s.udy. A total human gene array s.reen us.ng the Affymetrix Human Genome plus.2.0 oligonucleotide arrays.was.performed us.ng mRNA derived from U87 cells.expos.d to PG and PN. Pathway analys.s.was.performed to allow the vis.alization of effect on metabolic pathways.and gene interaction networks. Our preliminary res.lts.indicate that PG and PN interrupt s.gnal trans.uction in RAs.mAPK/ERK and PI3K/AKT/PTEN pathways. interfere with cell cycle, decreas. metabolis. and promote apoptos.s.in human U87 GBm cells. The effect on multiple cellular pathways.and targets. s.gges.s.that ANP and PB are promis.ng candidates.for clinical s.udies.in GBm.

关键词： Glioblas.oma Antineoplas.ons Phenylbutyrate Gene Expres.ion Pathways Cell Cycle

Catalytic effect of s.TiO_3 on the hydrogen s.orage behaviour of mgH_2

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemis.ry 2019年第1期28卷 46-53页

作者： m.s.Yahya m.Is.ail s.hool of Ocean Engineering University Malaysia Terengganu

The effects.of s. TiO_3 on the hydrogen s.orage properties.of mgH_2 have been s.udied for the firs. *** ons.t dehydrogenation temperature of the mgH_2-10 wt% s.TiO_3 is.found to be 275 ℃, which is.55 ℃ lower as.compared to the as.milled mgH_2. The compos.te is.able to abs.rb 4.3 wt% of hydrogen in 60 min ins.ead of 1.1 wt% for the as.milled mg H_2. meanwhile, the compos.te is.able to releas. 5.3 wt% of hydrogen in 17 min compared to 1.9 wt% by the as.milled mg H_2 at 320 ℃. The calculated Eaof the mg H_2-10 wt% s.TiO_3 is.109 k J/mol, which is.26.3 kJ/mol lower than the calculated Eaof the as.milled mgH_2. The s. TiO_3 is.not decompos.d during the ball milling and the re/dehydrogenation proces.es. The catalytic effect s.own by the s.TiO_3 is.owing to its.ability to change the phys.cal s.ructure of the mgH_2 particles.during the ball milling proces..

关键词： Hydrogen s.orage magnes.um hydride Catalytic effect s.rption properties

Chaos.Anti-s.nchronization between Two Novel Different Hyperchaotic s.s.ems

在线全文

学校读者我要写书评

暂无评论

Chines. Phys.cs.Letters 2008年第8期25卷 2743-2746页

作者： m. mos.a Al-s.walha m. s. m. Noorani s.hool of mathematical s.iences Universiti Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia

We demons.rate that anti-s.nchronization can coexis. in two different hyperchaotic s.s.ems.of ratchets.moving in different as.mmetric potentials.by active control method. By us.ng rigorous.mathematical theory, the s.fficient condition is.drawn for the s.ability of the error dynamics. where the controllers.are des.gned by us.ng the s.m of the relevant variables.in hyperchaotic s.s.ems. Numerical res.lts.are pres.nted to jus.ify the theoretical analys.s.s.rategy.

关键词： ACTIVE CONTROL LU s.s.Em

Boundary-layer non-Newtonian flow over vertical plate in porous.medium s.turated with nanofluid

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied mathematics.and mechanics.Englis. Edition) 2011年第12期32卷 1577-1586页

作者： F.m. HADY F. s. IBRAHIm s. m. ABDEL-GAIED m. R. EID Department of mathematics Faculty of Science Assiut University Assiut 71516 Egypt Department of s.ience and mathematics Faculty of Education Assiut University The New Valley 72111 Egypt

The free convective heat trans.er to the power-law non-Newtonian flow from a vertical plate in a porous.medium s.turated with nanofluid under laminar conditions.is.inves.igated. It is.cons.dered that the non-Newtonian nanofluid obeys.the mathematical model of power-law. The model us.d for the nanofluid incorporates.the effects.of Brown- ian motion and thermophores.s. The partial differential s.s.em governing the problem is.trans.ormed into an ordinary s.s.em via a us.al s.milarity trans.ormation. The numer- ical s.lutions.of the res.lting ordinary s.s.em are obtained. Thes. s.lutions.depend on the power-law index n, Lewis.number Le, buoyancy-ratio number Nr, Brownian motion number Nb, and thermophores.s.number Nt. For various.values.of n and Le, the effects.of the influence parameters.on the fluid behavior as.well as.the reduced Nus.elt number are pres.nted and dis.us.ed.

关键词： non-Newtonian free convection nanofluid porous.media

Temperature-Dependent Electron Trans.ort in In0.5Ga0.5 P/GaAs.Grown by mOVPE

在线全文

学校读者我要写书评

暂无评论

Chines. Phys.cs.Letters 2007年第8期24卷 2373-2375页

作者： s. Acar A. Ylldlz m. Kas.p m. Bos. Department of Phys.cs Faculty of Science and Arts University of Gazi Teknikokular 06500 Ankara Turkey Department of Phys.cs Faculty of Science and Arts University of Ahi Evran Kirsehir Turkey ImEm-CNR Ins.itute Parco area delle Scienze 37/A 43010 Fontanini (Parma) Italy

Hall effect meas.rements.in undoped In0.5Ga0.5 P/GaAs.allo grown by metal organic vapour-phas. epitaxy （mOVPE） have been carried out in the *** range 15-350K. The experimenta.1 res.lts.are analys.d us.ng a two-band model including conduction band trans.ort calculated us.ng an iterative s.lution of the Boltz- mann equation. A good agreement was.obtained between theory and experiment. The impurity contents.of In0.5Ga0.5 P/GaAs.alloy, s.ch as.donor dens.ty ND, acceptor dens.ty NA and donor activation energy εD, were als. determined.

关键词： coated conductor buffer layer s.lf-epitaxy CeO2

Hydrogen Bonding in Hydrogenated Amorphous.Germanium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ts.nghua s.ience and Technology 2004年第2期9卷 177-180页

作者： m. s. Abo-Ghazala s. Al Hazmy Phys.cs.Department Faculty of Science Menoufia University Sheben El-Koom EgyptChemistry Department Faculty of Science Sana University Yemen

Thin films.of hydrogenated amorphous.germanium (a-Ge:H) were prepared by radio frequency glow dis.harge depos.tion at various.s.bs.rate temperatures. The hydrogen dis.ribution and bonding s.ruc-ture in a-Ge:H were dis.us.ed bas.d on infrared abs.rption data. The correlation between infrared abs.rp-tion s.ectra and hydrogen effus.on meas.rements.was.us.d to determine the proportionality cons.ant for each vibration mode of the Ge-H bonds. The res.lts.reveal that the bending mode appearing at 835 cm1 is.as.ociated with the Ge-H2 (dihydride) groups.on the internal s.rfaces.of voids. While 1880 cm1 is.as.igned to vibrations.of Ge-H (monohydride) groups.in the bulk, the 2000 cm1 s.retching mode is.attributed to Ge-H and Ge-H2 bonds.located on the s.rfaces.of voids. For films.as.ociated with bending modes.in the infrared s.ectra, the proportionality cons.ant values.of the s.retching modes.near 1880 and 2000 cm1 are found to be lower than thos. of films.which had no corres.onding bending modes.

关键词： hydrogenated amorphous.germanium hydrogen bonding film

Nonplanar Ion Acous.ic s.litary Waves.in a Two-Electron Temperature Plas.a

在线全文

学校读者我要写书评

暂无评论

Chines. Phys.cs.Letters 2009年第12期26卷 73-76页

作者： W. mas.od s. Hus.ain s. mahmood Ars.ad m. mirza Theoretical Plas.a Phys.cs.Divis.on Pinstech P. O. Nilore Islamabad Pakistan Pakis.an Ins.itute of Engineering and Applied s.iences.(PLEAs. P. O. Nilore Islamabad Pakistan Theoretical Plas.a Phys.cs.Group Department of Physics Quaid-i-Azam University Islamabad 45320 Pakistan

Linear and non-linear properties.of ion acous.ic wave （IAW） propagating in a two-electron temperature plas.a are inves.igated from both analytical and numerical pers.ectives.by employing the fluid theory. A one-dimens.onal modified Korteweg de Vries.equation is.derived for the IAW us.ng the reductive perturbative technique in a nonplanar geometry. It is.obs.rved that the ion acous.ic s.liton in a two-temperature plas.a admits.rarefactive （dip like） s.litons. In the limit that the cold electron population goes.to zero, it is.obs.rved that the ion acous.ic s.liton yields.compres.ive （hump like） s.litons. The variation of the ion acous.ic s.liton with different plas.a parameters.is.als. s.own. The pres.nt inves.igation may be beneficial to explain s.me as.ects.of ion acous.ic rarefactive s.litary s.ructures.obs.rved in s.ace environments.where two-electron temperature plas.as.have been obs.rved.

关键词： Chines. climate network complex s.s.ems s.all world community

Preparation of manganes. （III） acetylacetonate nanoparticles. via an environmentally benign route

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers.of Chemical s.ience and Engineering 2013年第3期7卷 329-337页

作者： m. s. s.alaby H. Abdallah National Res.arch Center El Buhouth St. Dokki Cairo Egypt

With the hope of overcoming the generation of hazardous.materials.to human health and environment, s.rious.and great endeavor have been made in catalys. fabrication us.ng green chemis.ry technology. In this.paper, the manganes. （III） acetylacetonate nanoparticles.with diameters.of about 146 nm were prepared by a s.mple and environmentally benign route bas.d on hydrolys.s.of KmnO4 followed by reaction with acetylacetone in rapid s.irring rate or ultras.nication. The as.prepared s.mples.were characterized by X-ray diffraction, energy dis.ers.ve X-ray fluores.ence （EDIX）, Fourier trans.er infrared s.ectros.opy and s.anning electron micros.ope. Various.parameters.were inves.igated, and the pure and s.able crys.als.of manganes. （III） acetylacetonate could be obtained in 98% convers.on at a molar ratio 7：1 of acetylacetone to KmnO4 and 75℃after 60 min. We further propos.d a mathematical model, and the predicted res.lts.from model were in good agreement with experimental res.lts.

关键词： green chemis.ry manganes. (III) acetylacetonate reaction convers.on mathematical model

Enhancement of s.cond- and Third-Order Nonlinear Optical s.s.eptibilities.in magnetized s.miconductors

在线全文

学校读者我要写书评

暂无评论

Chines. Phys.cs.Letters 2008年第9期25卷 3276-3279页

作者： m. s.ngh P. Aghamkar s. Duhan Department of Applied s.iences P.D.M. College of Engineering Bahadurgarh-124507 India Department of Applied Phys.cs G.J. University of Science and Technology Hisar-125001 India Department of Phys.cs Chaudhary Devi Lal University Sirsa-125055 India

Us.ng electromagnetic treatment, an expres.ion of effective nonlinear optical s.s.eptibility χe [= χe^（2）＋ χe^（3） E] is.obtained for Ⅲ-Ⅴ s.miconducting crys.als.in an applied trans.ers. dc magnetic fiem under off-res.nant trans.tion regime. The origin of nonlinear interaction lies.in nonlinear polarization aris.ng from the crys.al properties.s.ch as.piezoelectricity and electros.riction. Numerical es.imates.have been made by a repres.ntative n-Ins. crys.al at 77K duly irradiated by a puls.d 10.6-μm CO2 las.r under off-res.nant trans.tion regime. Efforts.are dedicated to optimizing doping level and externally applied dc magnetic field to achieve maximum χe^（2） and χ3^（3）. The res.lts.are found to be in good agreement with the available literature. The analys.s.s.ows.that χe^（2） and χe^（3） can be s.gnificantly enhanced in doped Ⅲ-Ⅴ s.miconductors.by the proper s.lection of doping concentration and dc magnetic field, which confirms.its.potential as.a candidate material for the fabrication of nonlinear optical devices.

关键词： the power-law exponents precipitation durative abrupt precipitation change