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Nd^(3+)-sensitized upconversion nanoparticle coated with antimony shell for bioimaging and photothermal therapy in vitro using single laser irradiation

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Journal of Rare Earths 2022年第6期40卷 862-869,I0001页

作者： solomon Tiruneh Dibaba Yao Xie Wensong Xi Artur Bednarkiewicz Wei Ren Lining Sun Research Center of Nano Science and Technology College of SciencesShanghai UniversityShanghai 200444China Physics Department International Centre for Quantum and Molecular StructuresShanghai UniversityShanghai 200444China Applied Physics Department School of Applied Natural ScienceAdama Science and Technology UniversityAdama 1888Ethiopia School of Environmental and Chemical Engineering Shanghai UniversityShanghai 200444China Institute of Low Temperature and Structure Research Polish Academy of Sciences50-422 WroclawPoland

Combining treatment and diagnosis,called theranostics,which is achieved within single nanoparticle is an ultimate goal of many ***,we developed a new nanotheranostic agent-Nd^(3+)-sensitized upconversion nanoparticles core for dual modal imaging(i.e.,upconversion luminescence imaging and magnetic resonance imaging) and antimony nanoshell for photothermal therapy(PTT).The core-shellshell upconversion nanoparticles(NaYF_(4):Yb,Er@NaYF_(4):Yb,Nd@NaGdF_(4):Nd,named as UCNP) were firstly synthesized using thermal decomposition method and then were coated by antimony shell over the surface of UCNP using simple cost and time effective new ***,the surface of UCNP@Sb nanostructures was modified with DSPE-PEG in order to enhance the water solubility and *** final nanotheranostic agent,named as UCNP@Sb-PEG,exhibits very low toxicity,good biocompatibility,very good photothermal therapeutic effect,and efficient upconversion luminescence(UCL) imaging of HeLa cells under only one laser(808 nm) *** antimony shell is quenching the upconversion emission in pristine nanotheranostic agent,but interestingly,the UCL intensity of the agent recovers progressively under 808 nm laser irradiation due to light induced degradability of antimony ***,high longitudinal relaxivity(r_(1)) obtained from the experiment approves excellent potential of the nanotheranostic agent for T_(1)-weighted magnetic resonance imaging application.

关键词： Rare earths Upconversion luminescence Nanotheranostic agent Antimony shell Bioimaging Photothermal therapy

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Biomarkers of end of shift exposure to disinfection byproducts in nurses

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Journal of Environmental Sciences 2017年第8期29卷 217-223页

作者： solomon Ioannou Xanthi D.Andrianou Pantelis Charisiadis Konstantinos C.Makris Cyprus International Institute for Environmental and Public Health Cyprus University of Technology Limassol 3041 Cyprus

Increased disinfectant use commonly takes place in hospitals and other health care settings. A cross-sectional study among active nurses in two Cypriot public hospitals（n = 179） was conducted to examine the prevalence of exposure to disinfection byproducts（DBPs）, such as trihalomethanes（THMs） using both self-reported information and biomarker *** objectives of this study were to： i） quantify the magnitude and variability of occupational exposure to disinfectants/DBPs in nurses, ii） generate job exposure matrices（JEM） and job task exposure matrices（JTEM） for disinfectants, and iii） assess the major determinants of urinary THMs in nurses. End of shift urinary total THM values showed high variability among the nurses, but did not differ between hospitals. The disinfectant group of alcohols/phenols was used by 〉 98% of nurses, followed by octenidine（82%）, iodine and chlorine（39%, each）,chlorhexidine（25%）, formaldehyde（12%）, hydrogen peroxide（11%）, and peracetic acid/ammonia/quaternary ammonium compounds（QACs）, all being 〈 8% each. Chlorine use during the past 24 hr was associated with significantly（p 〈 0.05） lower brominated THMs（Br THMs） after adjusting for age, gender and BMI, while a positive association was shown for TCM and the sum of all THMs（TTHMs）, albeit not significant. Nurses were exposed to nearly double the levels of TTHMs and BrT HMs（median and IQR, 1027 [560, 2475] ng/g and 323 [212,497] ng/g, respectively） when compared to those of the general population（552 [309,989] ng/g and 152 [87,261] ng/g, respectively）. This was the first occupational health dataset reporting measurements of biomarkers of end of shift exposures to disinfectants/DBPs.

关键词： Nurses Disinfectants Disinfection Exposure Biomarker Job exposure matrix Healthcare

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犹太人与犹太教

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作者： (英)Norman solomon

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Challenges Faced by SMEs in African Countries:Case Study Focusing on Uganda

Challenges Faced by SMEs in African Countries:Case Study Foc...

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作者： AKANDWANAHO solomon（王蒙）南昌大学

学位级别：硕士

自从20世纪90年代以来,大量采用描述性统计数据的研究识别了很多影响中小企业发展的因素。基于第二手研究数据,本文以非洲欠发达国家乌干达为重点,考察了中小企业在发展过程中所面临的一些挑战。起于20世纪90年代的乌干达私有化和公共... 详细信息

自从20世纪90年代以来,大量采用描述性统计数据的研究识别了很多影响中小企业发展的因素。基于第二手研究数据,本文以非洲欠发达国家乌干达为重点,考察了中小企业在发展过程中所面临的一些挑战。起于20世纪90年代的乌干达私有化和公共部门改革为中小企业的发展提供了良好的基础。截止2002年,中小企业为乌干达提供了大约2,000,000个工作岗位。然而,中小企业在发展过程中面临管理技能和资金的缺乏等许多问题。中小企业破产的原因是多方面的,如管理水平低下以及政治、经济、社会、文化和环境等因素,这些因素交互影响中小企业的发展。本文分为五章,分别为引言、文献回顾、乌干达中小企业所面临的挑战、乌干达中小企业发展的应对策略以及本文研究总结。

关键词：中小企业发展问题挑战建议

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Pharmacognostic standardisation of Hilleria latifolia(Lam.) ***.(Phytolaccaceae)

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Asian Pacific Journal of Tropical Biomedicine 2014年第12期4卷 941-946页

作者： Isaac Kingsley Amponsah Abraham yeboah Mensah Antonia Otoo Merlin Lincoln Kwao Mensah Jato Jonathan Department of Pharmacognosy Faculty of Pharmacy and Pharmaceutical SciencesKwame Nkrumah University of Science and Technology Department of Herbal Medicine Faculty of Pharmacy and Pharmaceutical Sciences.Kwame Nkrumah University of Science and Technology

Objective:To establish the pharmacognostic characters for the correct identification and quality control of Hilleria latifolia(***),an important herb in Ghanaian folklore medicine,for the treatment of infections,pain and ***:The macro-morphological,qualitative and quantitative microscopic features,physicochemical and phytochemical features of the medicinally used parts of *** were evaluated using standard ***:The plant has simple,alternate leaves with entire *** lamina is ovate to broadly lanceolate with an acuminate *** is hypostomatic with anomocytie *** plant contains abundant prismatic crystals in all *** grains abound in the *** quantitative indices of the leaf and physicochemical parameters have also been ***:The pharmacognostic features established in this study may be used as part of the pharmacopoeia! standard for the correct identification and quality control of ***.

关键词： Hilleria latifolia Pharmacognostic features standardization Thin layer chromatography chromatogram Quantitative microscopy Fluorescence analysis

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The burden of and risk factors for active trachoma in the North and South Wollo Zones of Amhara Region,Ethiopia:a crosssectional study

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Infectious Diseases of Poverty 2017年第1期6卷 1270-1281页

作者： Beselam Tadesse Alemayehu Worku Abera Kumie solomon Abebe Yimer Ethiopian Institute of Water Resources(EIWR) Addis Ababa UniversityAddis AbabaEthiopia School of Public Health College of Health SciencesAddis Ababa UniversityAddis AbabaEthiopia Department of Microbiology Oslo University HospitalOsloNorway

Background:Trachoma is a disease of the eye,caused by the bacteria Chlamydia trachomatis,which can lead to blindness if left *** is one of the most trachoma-affected countries in the *** objective of this study was to determine the prevalence of and associated risk factors for active trachoma among children in selected woredas of North and South Wollo Zones in Amhara Region,***:This study was a community-based,cross-sectional study,which was conducted from October to December 2014 among children aged 1-8.A four-stage random cluster sampling technique was employed to select the study areas and *** each selected household,one child was clinically assessed for active trachoma.A structured questionnaire was used to collect sociodemographic,behavioral,and clinical *** logistic regression analysis was used to analyze the association between predictor variables and active ***:The overall prevalence of active trachoma among 1358 children was found to be 21.6%(95%CI:19.4-23.8%).When analyzed by the presence or absence of individual WHO simplified system signs of active trachoma,trachomatous inflammation-follicular cases constituted18%(95%CI:15.9-20.2%),while 4.7%(95%CI:3.6-5.8%)were trachomatous inflammation-intense *** discharge(aOR=5.2;95%CI:3.3-8.2),nasal discharge(aOR=1.8;95%CI:1.2-2.7),time taken to fetch water(aOR=0.02;95%CI:0.01-0.05),frequency of hand and face washing(aOR=4.4;95%CI:1.1-17.8),and access to a latrine(aOR=0.006;95%CI:0.001-0.030)were found to be independently associated with the presence of active ***:There is a high burden of active trachoma among children in the study *** of personal hygiene and limited access to a safe water supply and latrines were associated with increased prevalence of active *** order to reduce the burden of active trachoma,facial cleanliness and environmental improvement components of the SAFE strategy should be up

关键词： North Wollo South Wollo Amhara region Ethiopia Trachoma Prevalence SAFE strategy Wash

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Exclosures restored the density and root colonization of arbuscular mycorrhizal fungi in Tigray, Northern Ethiopia

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Ecological Processes 2017年第1期6卷 339-350页

作者： Emiru Birhane Kide Mogos Gebremedihin Tewodros Tadesse Mengsteab Hailemariam Negasi solomon Department of Land Resources Management and Environmental protection Mekelle UniversityPO Box 231MekelleEthiopia Faculty of Environmental Sciences and Natural Resource Management Norwegian University of Life SciencesPO Box 50031432ÅsNorway Department of Natural Resource Economics and Management Mekelle UniversityPO Box 231MekelleEthiopia

Introduction:Exclusion of grazing animals and tree plantations were among the methods used for the restoration of degraded lands in tropical semiarid *** can foster secondary forest succession by improving soil conditions and modifying microclimate for understory *** paper compared the arbuscular mycorrhizal fungi(AMF)spore density,root colonization of woody plants and soil chemical properties under exclosure with increasing age,and grazing land at different slope ***:The study was conducted in northern Ethiopia from 12 exclosure sites paired each with adjacent grazing land in total from 24 sites with four treatments replicated three *** the entire study,216 plots were examined of which 108 were in exclosures and 108 in communal grazing *** were four age classes and three slope positions in each of the land *** soil and root samples were collected using nested plots measuring 100m2 from four sides of 1763 plants for spore enumeration and root *** for chemical properties were collected from the four corners and center of 5 m×5 m ***:All the 61 woody plant species that belong to 41 families were colonized by *** density and root colonization were significantly higher in exclosures as compared to grazing land and increased with increasing ages of *** slope had significantly higher spore density and root colonization than middle and upper *** chemical properties were significantly higher in the exclosure,oldest age of exclosure,and foot slope position(except P).AMF spore density and root colonization were significantly positively correlated with soil chemical ***:Exclosures are helpful to restore the AMF spore density and root colonization of woody species and soil fertility.

关键词： Spore density Root colonization Age of exclosure Slope position

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The influence of genetics on epilepsy syndromes in infancy and childhood

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Acta Epileptologica 2022年第4期5卷 217-226页

作者： Elissa Yozawitz solomon L.Moshé Isabelle Rapin Division of Child Neurology and Saul R.Korey Department of Neurology Albert Einstein College of MedicineBronxNY10467USA Department of Pediatrics Albert Einstein College of MedicineBronxNY10467USA Laboratory of Developmental Epilepsy Albert Einstein College of MedicineBronxNY10461USA Comprehensive Einstein/Montefiore Epilepsy Center Albert Einstein College of MedicineBronxNY10467USA Dominick P.Purpura Department of Neuroscience Albert Einstein College of Medicine1410 Pelham Parkway SouthKennedy Center Rm 316BronxNY10461USA

Genetics is rapidly evolving and is actively playing a role in how we diagnose and manage *** definition of an epilepsy syndrome has changed throughout the *** International League Against Epilepsy(ILAE)has developed a classification of the epilepsies and has recently described specific epilepsy syndromes taking into account emerging genetic information which is rapidly evolving as well as etiology-specific *** genetics can help clarify the syndrome and its *** review provides a history of the definition of a syndrome,and the evolving contribution of genetic information that is part of the syndromic *** provide few examples of several phenotypes/genotypes of epilepsy syndromes in infancy and childhood and treatment issues that may arise from the available genetic *** syndromes and their genetics have been rapidly changing as new gene technologies are being *** genetics can help clarify the syndrome,its treatment,and will help change the field of epilepsy to improve patients qualify of life by creating new means of preventing,controlling,and curing epilepsy.

关键词： Syndrome Epilepsy syndrome Genetics History of epilepsy genetics ILAE history

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Applying tuberculosis management time to measure the tuberculosis infectious pool at a local level in Ethiopia

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Infectious Diseases of Poverty 2017年第1期6卷 1392-1400页

作者： Senedu Bekele Gebreegziabher Gunnar Aksel Bjune solomon Abebe Yimer Amhara Regional State Health Bureau Bahir DarEthiopia Department of Community Medicine Institute of Health and SocietyUniversity of OsloOsloNorway Oslo University Hospital OsloNorway Department of Bacteriology and Immunology Division of Infectious Disease ControlNorwegian Institute of Public HealthOsloNorway

Background:Measuring the size of the infectious pool of tuberculosis(TB)is essential to understand the burden and monitor trends of TB control program *** study applied the concept of TB management time to estimate and compare the size of the TB infectious pool between 2009 and 2014 in West Gojjam Zone of Amhara Region,***:New sputum smear-positive and smear-negative pulmonary TB(PTB)and retreatment cases who attended 30 randomly selected public health facilities in West Gojjam Zone from October 2013 to October 2014 were consecutively enrolled in the *** order to determine the infectious period,the TB management time(number of days from the onset of cough until start of anti-TB treatment)was computed for each patient *** number of undiagnosed TB cases was estimated and hence the TB management time for the undiagnosed category was *** total size of the TB infectious pool during the study period for the study zone was estimated as the annual number of infectious person ***:New smear-positive and smear-negative PTB cases contributed 25,050 and 12,931 infectious person days per year to the TB infectious pool,*** retreatment and presently undiagnosed cases contributed 8840 and 34,310 infectious person days per year,*** total size of the TB infectious pool in West Gojjam Zone during the study period was estimated at 81,131 infectious person days per year or 3405 infectious person days per 100,000 population per *** to a similar study done in 2009 in the study area,the current study showed reduction of the TB infectious pool by 244,279 infectious person ***:TB management time is a simple and practical tool that may help to estimate and compare the changes in the size of the TB infectious pool at local *** may also be used as an indicator to monitor the changes in TB control program performance.

关键词： Tuberculosis TB management time Infectious pool West Gojjam zone Ethiopia

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Impact of radiation pressure and circumstellar dust on motion of a test particle in Manev’s field

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Astrodynamics 2021年第2期5卷 77-89页

作者： Jagadish Singh solomon Okpanachi Omale Lawrence O.Inumoh Felix Ale Department of Mathematics Faculty of Physical SciencesAhmadu Bello UniversityZariaNigeria Engineering and Space Systems Department National Space Research and Development Agency(NASRDA)Obasanjo Space CentreAbujaNigeria

In this paper,we present a study on the impact of radiation pressure and circumstellar dust on the motion of a test particle in the framework of the restricted four-body problem under the Manev’s *** show that the distribution of equilibrium points on the plane of motion is slightly different from that of the classical Newtonian *** the aid of the Lyapunov characteristic exponents,we show that the system is sensitive to changes in initial conditions;hence,the orbit of the system is found to be chaotic in the phase space for the given initial ***,a numerical application of this model to a stellar system(Gliese 667C)is considered,which validates the dependence of the equilibrium points on the mass *** show that the non-collinear equilibrium points of this stellar system are distributed symmetrically about the x-axis,and five of them are linearly *** basins of attraction of the system show that the equilibrium points have irregular boundaries,and we use the energy integral and the Manev parameter to illustrate the zero-velocity curves showing the permissible region of motion of the test particle with respect to the Jacobi constant.

关键词： Manev potential circumstellar dust Lyapunov characteristic exponents(LCEs) stability chaos basins of attraction

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