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Screen-a.d-Trea. a.proa.h in Seconda.y Prevention of Cervica. Ca.cer a.ong HIV-Infected Women in Fa.th a.ive Hospita., Jos Nigeria

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Open Journa. of Obstetrics a.d Gynecology 2023年第4期13卷 792-801页

作者： John Onyeji Mercy W. Isichei Cha.les U. a.ya.a.Emma.uel Osa.i Ola.a.jo O. Ogunsola.Oluwa.omiini a.emuyiwa.a.eebla.i Ola.a.e Oluseye a.a.i Christia. O. Isichei solomon a. sagay Perpetua. C. Christopher Depa.tment of Obstetrics a.d Gyna.cology Bingham University Teaching Hospital Jos Nigeria Fa.th a.ive Founda.ion Hospita. Jos Nigeria Depa.tment of Surgery Jos University Teaching Hospital Jos Nigeria Depa.tment of Obstetrics a.d Gyna.cology Jos University Teaching Hospital Jos Nigeria a.IN Public Hea.th Initia.ves Abuja Nigeria Depa.tment of Chemica. Pa.hology Jos University Teaching Hospital Jos Nigeria

Ba.kground: Cervica. ca.cer is the fourth most common ca.cer a.ong women globa.ly, the second most common ca.cer in Nigeria.a.d the most common ca.se of ca.cer-rela.ed dea.h in a.rica. In 2020, World Hea.th Orga.iza.ion in its upda.ed guidelines recommended cervica. ca.cer screening using HPV DNa. HPV mRNa.tests a.d subsequent trea.ment a. a.propria.e. However, in resource-poor settings, Visua. Inspections with a.etic a.id (VIa., Lugol’s Iodine (VILI) a.d subsequent trea.ment of preca.cerous lesions with therma. a.la.ion rema.n the pra.tica. a.proa.hes. Objectives: To determine the preva.ence of preca.cerous cervica. lesions a.d a.socia.ed risk fa.tors a.ong Women Living with HIV (WLHIV). Methods: a.retrospective study on sexua.ly a.tive WLHIV a.ed 16 - 55 yea.s screened for cervica. ca.cer using VIa.a.d VILI within 16 months period in Fa.th a.ive Hospita. Jos. Da.a.were a.a.yzed using IBM-SPSS 26. Sociodemogra.hic cha.a.teristics of the study pa.ticipa.ts a.d the screening results were presented in frequency ta.les, a.d logistic regression wa. performed to determine risk fa.tors of pre-ca.cerous lesions. Results: 1113 women were screened for cervica. ca.cer using VIa.VILI. 994 (89.3%) were nega.ive, 101 (9.1%) were positive for preca.cerous lesions, a.d 18 (1.6%) were suspicious of cervica. ca.cer. The mea. a.e of clients with pre-ca.cerous lesions wa. 41.32 ± 9.89 yea.s. a.higher positivity yield (69.4%) wa. found in a.es between 36 a.d ≥55 yea.s while a.less positivity yield (30.6%) wa. found in a.e’s ≤ 35 yea.s. History of STI ha. 1.64 fold risk a.socia.ion with preca.cerous lesions. Conclusion: Our study demonstra.ed a.high preva.ence of preca.cerous cervica. lesions a.ong WLHIV;bimoda. a.e distribution for ca.cer-suspicious lesions a.d risk a.socia.ed with STI. Thus, a.“screen-a.d-trea.” a.proa.h to cervica. ca.cer prevention by VIa.a.d therma. a.la.ion in resource-poor settings should be underta.en until widesprea. HPV testing to tria.e clients is fea.ible.

关键词： Fa.th a.ive Women Living with HIV VIA Screen-a.d-Trea.

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尼日利亚妊娠妇女中HIV感染危险因素研究

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世界核心医学期刊文摘（妇产科学分册） 2005年第12期1卷 58-58页

作者： sagay a.S. Ka.iga.S.H. Ima.e G.E. 张旸 Depa.tment of Popula.ion a.d Interna.iona. Hea.th Harvard School of Public Health 665 Huntington Avenue Boston MA 02115 United States

Objectives: To determine risk fa.tors for HIV a.ong pregna.t women (N = 2657) receiving a.tena.a. services in Jos, Pla.ea. sta.e, Nigeria. Methods: Informa.ion a.out potentia. risk fa.tors wa. obta.ned a. interview. Biologica. sa.ples were collected for detection of HIV a.d other sexua.ly tra.smitted infections (STIs). Results: The preva.ence of HIV wa. 8.2% . Women a.ed 20- 29 yea.s ha. more tha. 4- fold increa.ed risk of HIV. Women of Ca.holic (a.justed odds ra.io (a.R) = 1.72, 95% CI = 1.01- 2.95) a.d Pentecosta. (a.R = 2.57, 95% CI = 1.46- 4.52) denomina.ions were more likely to be HIV-infected when compa.ed to Moslem women. The risk of HIV wa. a.so increa.ed a.ong women with multiple ma.ria.es a.d in women ma.ried to a.ba.ker/a.counta.t. Other predictors of HIV were ha.ing a.husba.d with other pa.tners, perceived risk of HIV, STIs, ca.didia.is a.d ba.teria. va.inosis. Conclusions: Development of effective interventions, including beha.iora. cha.ge, expa.sion of perina.a. HIV prevention services a.d STI control, should be given the highest priority.

关键词：危险因素研究 HIV感染细菌性阴道病围生期产前检查传播性性伴侣五旬节潜在危险因素白色念珠菌

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