检索结果-南通市图书馆

Neural Regeneration Research 2025年第6期20卷 1699-1700页

作者： Seyed Mojtaba Hosseini soheila karimi-abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada Manitoba Multiple Sclerosis Research Center WinnipegMBCanada Children Hospital Research Institute of Manitoba WinnipegMBCanada

Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord undergoes a cascade of secondary injury mechanisms that are driven by disruption of the blood-spinal cord ba rrier,vascula r inju ry,glial reactivity,neu roinfla mmation,oxidative stress,lipid peroxidation,and glutamate excitotoxicity that culminate in neuronal and oligodendroglial cell death,demyelination,and axonal damage(Alizadeh et al.,2019).To achieve a meaningful functional recovery after SCI,regeneration of new neurons and oligodendrocytes and their successful growth and integration within the neural network are critical steps for reconstructing the damaged spinal cord tissue (Fischer et al.,2020).

关键词： peroxidation Fischer injury

Neuregulin-1:a novel regulator of glial response in spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第10期12卷 1616-1617页

作者： Hardeep Kataria soheila karimi-abdolrezaee Regenerative Medicine Program Department of Physiology and PathophysiologySpinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegManitobaCanada

Spinal cord injury （SCI） results in a dysregulated microenvi- ronment that is largely driven by the immediate and robust response of resident astrocytes and microglia （Filous and Silver, 2016）.

关键词： Neuregulin-1:a novel regulator of glial response in spinal cord injury SCI

Emerging role of neuregulin-1beta1 in pathogenesis and progression of multiple sclerosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第1期18卷 133-134页

作者： Seyyed Mohyeddin Ziaee soheila karimi-abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CenterRady Faculty of Health SciencesUniversity of ManitobaChildren Hospital Research Institute of ManitobaWinnipegMBCanada

Multiple sclerosis(MS)is a chronic immune-mediated disorder of the central nervous system(CNS)that causes focal demyelinating lesions,followed by axonal and neuronal *** genetic and environmental factors are found to be associated with MS *** MS etiology seems to be multifactorial and needs further elucidation,it is understood that the response of an immune system to specific myelin antigens triggers the onset of MS(Dendrou et al.,2015).However,how the autoimmune response initiates against myelin,and the cellular and molecular mechanisms underpinning the development and progression of MS are not fully ***,deconstructing MS pathogenesis is of paramount importance for identifying novel diagnostic and therapeutic targets for this complex disease.

关键词： pathogenesis sclerosis degeneration

Role of chondroitin sulfate proteoglycan signaling in regulating neuroinflammation following spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2018年第12期13卷 2080-2082页

作者： Scott M.Dyck soheila karimi-abdolrezaee Department of Physiology and Pathophysiology the Regenerative Medicine Program the Spinal Cord Research Center University of Manitoba

Spinal cord injury （SCI） elicits a robust inflammatory response that is a hallmark of the secondary injury mechanisms. Neuroinflammation is orchestrated initially by the response of resident astrocytes and microglia to injury, which subsequently facilitates the recruitment of peripheral immune cells into the SCI lesion （Orr and Gensel, 2018）. This inflammatory response contributes to cell death and tissue degeneration through the production of pro-inflammatory cytokines and chemokines, free radicals and proteolytic enzymes. However, neuroinflammatory cells also play beneficial regulatory role in repair mechanisms after SCI by adopting a reparative and wound healing phenotype （Orr and Gensel, 2018; Tran et al., 2018）. Hence, understanding the underlying mechanisms by which immune cells are reg- ulated within the microenvironment of injury would aid in harnessing the reparative potential of inflammation following SCI.

关键词： Role of chondroitin sulfate proteoglycan signaling in regulating neuroinflammation following spinal cord injury PTP SCI

ORGANOSOLUBLE AND THERMALLY STABLE POLYIMIDES DERIVED FROM A NEW DIAMINE CONTAINING BULKY-FLEXIBLE TRIARYL PYRIDINE PENDENT GROUP

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2011年第4期29卷 465-474页

作者： Mousa Ghaemy soheila Khajeh Faculty of Chemistry University of MazandaranBabolsarIran

A novel kind of aromatic diamine, N-（4-（4-（2,6-diphenyl pyridine-4-yl） phenoxy） phenyl）-3,5-diaminobezamide （DPDAB）, was synthesized via aromatic nucleophilic substitution of 3,5-dinitrobenzoylchloride with 4-（4-（2,6- diphenylpyridine-4-yl）phenoxy）aniline （DPPA）, followed by palladium-catalyzed hydrazine reduction. This monomer was used to prepare polyimides （PIs） based on reaction with several commerically avaiable tetracarboxylic dianhydrides such as pyromellatic dianhydride （PMDA）, benzophenone tetracarboxylic acide dianhydride （BTDA） and bicycle [2.2.2] oct-7-ene- 2, 3,5,6-tetracarboxylic dianhydride （BCDA）. These PIs had inherent viscosity in the range of 0.34-0.76 dL/g and showed good solubility in various aprotic polar solvents. The glass-transition tempratures （Tgs） of the PIs were in the range of 184-302℃, and showed high thermal stability with 10% weight loss in the temperature range of 360-500℃ under nitrogen atmosphere.

关键词： Polyimides Inherent viscosity Solubility Thermal stability DSC.

SYNTHESIS AND CHARACTERIZATION OF POLYAMIDES DERIVED FROM(4-(4-(2,6-DIPHENYLPYRIDIN-4YL)PHENOXY)PHENYL)-3,5-DIAMINOBEZAMIDE

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2012年第1期30卷 82-92页

作者： Mousa Ghaemy soheila Khajeh Faculty of Chemistry University of Mazandaran BabolsarIran

New types of polyamides containing pendent triaryl pyridine groups were successfully synthesized by direct polycondensation of a symmetry diamine,（4-（4-（2,6-diphenylpyridin-4yl）phenoxy）phenyl）-3,5-diaminobezamide（DPDAB）, and various aromatic and aliphatic dicarboxylic diacids in NMP using triphenyl phosphate（TPP） and pyridine as catalyst. The diamine and all the prepared polyamides were fully characterized by using FT-IR,~1H-NMR,UV-Vis spectroscopy, fluorimetry and elemental *** inherent viscosity of polyamides ranged from 0.45 dL/g to 0.68 dL/*** the polymers exhibited solubility in common polar aprotic solvents such as NMP,DMAc,DMF,DMSO,pyridine,HMPA,and even in less polar solvents such as THF and m-cresol at room *** properties of polyamides were evaluated by means of DSC,DMTA and *** polymers showed glass transition temperatures（T_g） in the range of 138-210℃. Their initial decomposition temperature（T_i） varied from 265℃to 310℃under N_*** dilute solution（0.2 g/dL） of polyamides in DMF exhibited fluorescence emission withλ_（max） in the range of 470-550 nm.

关键词： Polyamides Synthesis Direct polycondensation Solubility Thermal stability

Metal-organic framework-based materials as key components in electrocatalytic oxidation and reduction reactions

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2023年第12期87卷 540-567,I0014页

作者： soheila Sanati Ali Morsali Hermenegildo García Department of Chemistry Faculty of Basic SciencesTarbiat Modares UniversityTehran 14115175Iran Instituto Universitario de Tecnología Química Universidad Politecnica de ValenciaConsejo Superior de Investigaciones CientíficaSUniversitat Politècnica de ValènciaValència 46022Spain

Studies have extensively addressed the development of electrocatalytic technologies for energy storage and conversion,fuel production,and environmental *** processes such as different oxidation and reduction reactions play a vital and significant role in these *** this regard,efficient,inexpensive,and stable electrocatalysts capable can significantly promote electrochemical *** features of metal–organic frameworks(MOFs)such as their high porosity,tunable structure,size,and pore shape,high surface area,and redox properties have introduced them as an ideal electrocatalyst *** review is thus aimed at elucidating the role of MOF-based materials(pristine,derivatives and composites)as efficient electrocatalysts in energy and sensing-related oxidation and reduction reactions such as oxygen reduction reaction(ORR),hydrogen oxidation reaction(HOR),carbon dioxide reduction reaction(CO_(2)RR),urea oxidation reaction(UOR),alcohol oxidation reaction(AOR),nitrogen reduction reaction(NRR),and glucose oxidation reaction(GOR)in advanced energy and sensing ***,the structure–property relationship of the electrocatalyst was elaborated for each electrocatalytic ***,perspectives on the potential research topics for practical use of MOF-based electrocatalysts are *** present review can improve the interest in MOF-based electrocatalysts to study different oxidation and reduction reactions in energy and sensing systems.

关键词： Metal-organic frameworks Electrocatalyst Oxidation reaction Reduction reaction

Etiology of renal failure and peritoneal dialysis complications in Isfahan

在线全文

学校读者我要写书评

暂无评论

Health 2013年第10期5卷 1702-1705页

作者： soheila Mojdeh Shirin karimi Ali Mehrabi soheila Bakhtiari Al-Zahra Hospital Isfahan University of Medical Sciences Isfahan Iran Nursing and Midwifery School Isfahan University of Medical Sciences Isfahan Iran

Introduction: Worldwide specific diseases are jeopardizing people’s health in the world as well as in Iran. Chronic renal failure as a developed and irreversible failure is usually progressive. End Stage Renal Disease (ESRD) is a situation when renal function is not sufficient to preserve one’s life leading to acute uremia resulting in dialysis and/or kidney transplantation for the patients. Although dialysis methods bring about complications for the patients, peritoneal dialysis is relatively cost-effective and more convenient to survive. The present study aimed to investigate (the) Etiologic factor of renal failure and imposed complications of peritoneal dialysis in the patients of Isfahan Alzahra hospital. Materials and Methods: It was a cross-sectional descriptive study conducted on 67 patients in Isfahan Peritoneal Dialysis Center. The data from the patients were collected through a two-section questionnaire whose first section was allocated to demographic information and the second part was related to the disease and complications of peritoneal dialysis. The collected data were analyzed by SPSS version 18. Results: The findings showed that there were 39 (58%) males and 28 (42%) females. Mean age of the subjects was 48 (18.8) years old. Regarding marital status, 65% were married and 35% were single. Considering complications, 28 subjects (53.5%) had infectious complications while 24 subjects (46.2%) had non-infectious complications. The highest frequency in etiologic factor of renal failure was diabetes mellitus in 29 subjects (43.9%) and the lowest for polycystic kidney in 2 subjects (3%);in addition, hypertension was observed in 51 subjects (77.3%). Discussion: The most frequent and important complication of peritoneal dialysis catheters is infection, which may result in catheter loss and discontinuation of peritoneal dialysis (PD). Diabetes and hypertension were found as the most important etiologic factors for renal failure. They should also be considered a

关键词： Complications Peritoneal Dialysis Epidemiologic

The contribution of steel wallposts to out-of-plane behavior of non-structural masonry walls

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2023年第1期22卷 243-262页

作者： Fooad karimi Ghaleh Jough Department of Civil Engineering Final International UniversityKyreniaNorth Cyprusvia Mersin 10 Turkey

For years,non-structural masonry walls have received little attention by code developers and professional ***,significant efforts have been made to shed more light on out-of-plane(OOP)behavior of non-structural masonry *** updated provisions of the Iranian seismic code,bed joint reinforcements(BJRs)and steel wallposts have been suggested for *** are horizontal reinforcements;steel wallposts are vertical truss-like elements intended to provide additional OOP restraints for a *** contribution of BJRs has previously been investigated by the *** study is devoted to investigating the contribution of steel wallposts to the OOP behavior of non-structural masonry *** pre-validated 3D finite element(FE)models,the OOP behavior of 180 non-structural masonry walls with varying configurations and details are *** OOP pressure-displacement curve,ultimate strength,the response modification factor,and the cracking pattern are among the results presented in this *** is found that steel wallposts,especially those with higher rigidity,can improve the OOP strength of the *** contribution of wallposts in the case of shorter length walls and walls with an opening are more *** also indicate that masonry walls with wallpost generally have smaller modification factors compared to similar walls without wallpost.

关键词： masonry wall wallpost wind post bed joint reinforcement non-structural masonry wall out-of-plane behavior

Evaluating innovation ecosystem resiliency using agent-based modeling and systems dynamics

在线全文

学校读者我要写书评

暂无评论

Journal of Safety Science and Resilience 2024年第2期5卷 204-221页

作者： soheila Abdi Mehdi Yazdani Esmaeil Najafi Department of Industrial Engineering Science and Research BranchIslamic Azad UniversityTehranIran Department of Industrial Engineering Qazvin BranchIslamic Azad UniversityQazvinIran

Evaluating the resilience of the innovation ecosystem to maintain its performance,in the sense of resistance to disruption and recovery after it,has recently received more *** studies have been conducted to model different ecosystems and evaluate their ***,modeling the innovation ecosystem from a holistic perspective and performing a quantitative assessment of its resilience have received less *** paper models the innovation ecosystem holistically and evaluates its resilience index using a quantitative approach through five main *** the first step,a case study related to the innovation ecosystem of Iran's Ministry of Energy,called the Power Innovation Ecosystem,is modeled by combining system dynamics and agent-based *** validating the model in the second step,the disruption of the loss of experts is investigated in the third step,and all possible actions to recover each actor are *** the fourth step,the performance of the ecosystem is simulated before and after the disruption using the data gathered in the previous ***,resilience is calculated in two different ways in the fifth *** improvement solutions are also suggested when considering that the resilience index of the innovation ecosystem is at a medium *** research may assist policymakers in observing the resilience level of the innovation ecosystem based on the proposed *** applying strategic changes to this model,they can determine the effects of their policies and make the most appropriate decisions to increase the resilience of the innovation ecosystem.

关键词： Resilience index innovation ecosystem System dynamics Agent-based modeling