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Exploring the potential and safety of quantum dots in allergy diagnostics

Microsystems & Nanoengineering 2023年第6期9卷 1-23页

作者： Milad Mohkam Mohammad Sadraeian Antonio Lauto Ahmad Gholami Seyed Hesamodin Nabavizadeh Hossein Esmaeilzadeh soheila alyasin Allergy Research Center Shiraz University of Medical SciencesShirazIran Institute for Biomedical Materials and Devices(IBMD) Faculty of ScienceUniversity of Technology SydneySydneyNSW2007Australia School of Science University of Western SydneyCampbelltownNSW2560Australia School of Medicine University of Western SydneyCampbelltownNSW2560Australia Biotechnology Research Center Shiraz University of Medical SciencesShirazIran Department of Pharmaceutical Biotechnology School of PharmacyShiraz University of Medical SciencesShirazIran Department of Allergy and Clinical Immunology Namazi HospitalShiraz University of Medical SciencesShirazIran

Biomedical investigations in nanotherapeutics and nanomedicine have recently intensified in pursuit of new therapies with improved *** dots(QDs)are promising nanomaterials that possess a wide array of advantageous properties,including electronic properties,optical properties,and engineered biocompatibility under physiological *** to these characteristics,QDs are mainly used for biomedical labeling and theranostic(therapeutic-diagnostic)*** can be functionalized with ligands to facilitate their interaction with the immune system,specific IgE,and effector cell ***,undesirable side effects such as hypersensitivity and toxicity may occur,requiring further *** review systematically summarizes the potential uses of QDs in the allergy *** overview of the definition and development of QDs is provided,along with the applications of QDs in allergy studies,including the detection of allergen-specific IgE(sIgE),food allergens,and sIgE in cellular *** potential treatment of allergies with QDs is also described,highlighting the toxicity and biocompatibility of these ***,we discuss the current findings on the immunotoxicity of *** favorable points regarding the use of QDs for allergy diagnosis and treatment are noted.

关键词： allergy diagnosis potential

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