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Carotenoids: New Applications of “Old” Pigments

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Phyton-International Journal of Experimental Botany 2021年第4期90卷 1041-1062页

作者： Stefan M.Kolašinac Zora P.DajićStevanović sofija N.Kilibarda AleksandarŽ.Kostić Faculty of Agriculture University of BelgradeChair of AgrobotanyBelgrade11080Serbia Faculty of Agriculture University of BelgradeChair of Chemistry and BiochemistryBelgrade11080Serbia

Carotenoids represent a large group of mainly red,orange,and yellow natural metabolites mainly involved in regulation of many metabolic *** are beneficial for human *** study describes the importance,chemical composition and functioning of *** is well known that carotenoids support pigments acting in light absorbance mechanisms during photosynthesis,and are known to protect the chlorophyll molecules from oxidative stress and reactive oxygen species(ROS)*** are involved in signaling processes in plants,responses to environmental stresses,pollination,germination and reproduction,and development *** nutrients of strong antioxidant activity that is primarily linked to their polyene molecular structure,the carotenoids are reported as immune-enhancement and anticancer agents,which are also involved in prevention of eye-,gastric and neurocognitive disorders,and in regulation of obesity and *** the wide prospective applications of carotenoids as pharmaceuticals and nutraceuticals,there are some critical aspects associated with carotenoids’bioavailability and challenges in their *** mostly refers to the needs for identification and cloning of genes responsible for carotenoid biosynthesis and transformation and related development of transgenic carotenoid-rich *** the recent years,technologies of micro-and nanoencapsulation have addressed the needs of carotenoid entrapping to enhance their bioavailability,solubility and chemical stability,and to ensure the target delivery and manifestation of their strong antioxidant and other biological *** standard and some advanced analytic tools for carotenoid determination(e.g.,High performance liquid chromatography-HPLC,Liquid chromatography–mass spectrometry-LC-MS,Ultra high performance liquid chromatography-UHPLC,High-performance thin-layer chromatography-HPTLC and others),the vibrational spectroscopy techniques,primaril

关键词： Antioxidant and biological activity biosynthesis of carotenoids encapsulation raman spectroscopy role in plants

Splenic hamartomas in children

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World Journal of Clinical Cases 2024年第11期12卷 1909-1917页

作者： Maja Milickovic Petar Rasic sofija Cvejic Dejana Bozic Djordje Savic Tanja Mijovic Sava Cvetinovic Slavisa M Djuricic Department of Abdominal Surgery Mother and Child Health Care Institute of Serbia"Dr.Vukan Cupic"Belgrade 11000Serbia Faculty of Medicine University of BelgradeBelgrade 11000Serbia Department of Radiology The Children’s University HospitalBelgrade 11000Serbia Department of Clinical Pathology Mother and Child Health Care Institute of Serbia"Dr.Vukan Cupic"Belgrade 11000Serbia Faculty of Medicine University of Banja LukaBanja Luka 78000Bosnia and Herzegovina

Splenic hamartomas(SHs)are uncommon,benign vascular lesions of unclear etiology and are mostly found incidentally on abdominal images,at surgery,or at *** the first case description,in 1861,less than 50 pediatric SH cases have been reported in the *** this article,we have performed an analysis of all SH cases in children published in the literature to date and presented our case of an 8-year-old male with *** lesions in children were shown to cause symptoms more often than in the adult *** observed SH sizes in children ranged from a few millimeters to 18 cm,and the symptomatic lesions were mostly larger or *** most common clinical finding was *** of hypersplenism were present in children with a single SH larger than 4.5 cm(diameter range:4.5-18.0 cm)and in those with multiple hamartomas,ranging from a few millimeters to 5 *** percent of patients with available laboratory findings had hematological abnormalities such as anemia,thrombocytopenia,or *** symptoms and signs included abdominal pain,recurrent infections,fever,night sweats,lethargy,growth retardation,and weight *** use of multiple imaging modalities may suggest the preoperative diagnosis of a splenic mass in children and determine the therapeutic ***,the final diagnosis of SH relies on histopathological ***,including total or partial splenectomy(PS),is the mainstay of SH *** M et *** in children WJCC https://*** 1910 April 16,2024 Volume 12 Issue 11 Although total splenectomy carries a greater risk of overwhelming post-splenectomy infection than PS it has remained the most performed surgical procedure in children with *** the majority of pediatric patients with symptomatic SH,resolution of symptoms and resolution or improvement of cytopenias occurred after surgical treatment.

关键词： Splenic hamartoma Pediatric Splenoma Clinical features Radiological features Histopathology Treatment

Economic Cost-Effectiveness of the Implementation of the Quality Standard ISO 9001 in the Health Sector

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Journal of Modern Accounting and Auditing 2014年第8期10卷 912-916页

作者： Petkovska sofija Gjorgjeska Biljana University "Goce Delchev" Stip Republic of Macedonia

The quality standard ISO 9001 helps and enables organizations, regardless of the sector where they exist, to implement the quality management properly. Recent years have attracted attention to the possibilities of implementing this standard in the health sector and the economic viability of that long-term investment. Health care organizations are recognizing the value system that combines all the criteria for managing quality, including management of business, compliance and management of procedural steps, and most importantly, the total quality management. In general, the implementation of ISO 9001：2008 standard for quality in health care institutions is seen as an opportunity to improve the quality of health care, and the entire process is to be completed by reducing costs and improving services in the sector. The implementation of a quality standard is directed towards patients, medical staff, and management in order to achieve reduction and complete relief from the pain, correct and professional services, conducted services with an appropriate skilled and professional care to obtain results that are comparable to known standards, and protection services with appropriate insurance policies, and the management expects the implementation of a quality system to justify and return their investments. The methods used in this paper are based on the quality standard ISO 9001：2008--Quality Management System and the Guidelines for Improving Performance, developed based on ISO 9004：2000： Quality Management System-43uidelines for Continuous Improvement. These guidelines contain a big part of the text in ISO 9004：2000, but they are supplemented with specific guidelines for their implementation in the health sector. The implementation of the system and monitoring guidelines evidently contributes to the overall resolution and closure of problems in over 50% of cases. This not only results in saving money for the institution, but it also globally leads to reduced variations in

关键词： ISO 9001 ISO 9004:2000 guidelines for improvement

Insect Hydrocarbons. Biology, Biochemistry, and Chemical Ecology

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Insect Science 2012年第6期19卷 703-704页

作者： sofija Pavković‐Lučić Dragana Miličić Luka Lučić (Chair of Genetics and Evolution) (Chair of Animal Morphology Systematics and Phylogeny) (Chair of Animal Development) Institute of Zoology Faculty of Biology University of Belgrade Studentski trg 16 11000 Belgrade Serbia Email: sofija@bio.bg.ac.rs draganam@bio.bg.ac.rs luka@bio.bg.ac.rs

Gary J. Blomquist and Anne-Genevirve Bagnbres （eds.）, Cambridge University Press, 2010 ISBN 978-0- 521-89814-0, Hardback, pp. 492, 70.00 Who of us does not know how magic is love dancing in dragonflies, or waggle honebees＇ dance, flushing in the firefly, or traveling of ＂orange cloud＂ during migration of monarch butterflies？ And, if those behaviors are magical for us, how magical are they for themselves？ How special is insect ＂vocabulary＂ during their communication？

关键词： Insect Hydrocarbons Biology Biochemistry