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Heart Failure Prediction in Athletic Heart Remodeling among Long Distance Runners

World Journal of Cardiovascular Diseases 2022年第1期12卷 1-10页

作者： Hossam Abdel Aleem Shaheen manal Ahmed mohamed Fatma Hasan Abdel Basset mostafa Hamed Rashed Neethu Betty Theruvan soad A. mosbah Department of Cardiac Technology College of Applied Medical Sciences Imam Abdulrahman Bin Faisal University Dammam City Kingdom of Saudi Arabia Department of Biochemistry National Heart Institute Giza Egypt Department of Physical Sport Sohar University Sohar Oman

Background: Physical activity has a cardinal role in preventing and treating cardiovascular diseases. Understanding the changes that occur to the cardiac muscle in athletes is still doubtful whether it is only an adaptation to exercise or a concealed pathological condition. Most of these changes are well documented in apparently healthy heart and characterized by cardiac enlargement with Brady-arrhythmias specially individuals participating in long distance runners with exercise capacity without signs of cardiovascular disease. Methods: The study searched the subclinical myocardial necrosis by comparing two groups of young marathon runners, both groups were chosen from Al Gizera youth center in January 2018. First group included adults above the age of 18 years and ran for 12 km. and the second was under 18 years and ran for about 8 km. Both groups were volunteered for this study. They are monitored carefully with blood pressure, heart rate and respiratory rate and their blood samples were collected pre- and post-race immediately for assessment of cardiac markers NTproBNP, Galectin-3 and cTnI. Results: All cardiac markers were elevated post exercise compared to that achieved in pre-exercise regardless age of athletes. Also, pre-exercise adult results were higher in galectin-3 and cTnI but not in proBNP while there is no difference in the acute response in both groups. These results revealed micro cardiac necrosis due to long run exercise with possible bad prognosis. Conclusions: It is important to develop risk assessment and prediction methods for screening the young athletes and consider the term athletic heart as a subclinical disorder rather than physiological adaptation.

关键词： Athletes Exercise Phidippides Cardiomyopathy Remodeling

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Antiparasitic and apoptotic modulatory activities of curcumin and extracts of Nigella sativa L,Zingiber officinale Rosc.,and Punica granatum *** combination with spiramycin against chronic cerebral toxoplasmosis in immunocompromised mice

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Journal of Traditional Chinese medical Sciences 2024年第4期11卷 476-487页

作者： mennat-Elrahman A.Fahmy Amany A.Abdel-Aal soad I.Hassan maisa A.Shalaby manal Badawi marwa Esmat medical Parasitology Department Theodor Bilharz Research Institute(TBRI)Giza12685Egypt Department of medical Parasitology Faculty of MedicineCairo UniversityCairo11562Egypt Department of Postgraduate Studies&Scientific Research Armed Forces College of Medicine(AFCM)Cairo11711Egypt Department of Pathology National Research CentreGiza12622Egypt Department of medical Parasitology Faculty of MedicineMisr University for Science and Technology6th of October CityGiza12585Egypt

Objective:To examine the effect of coadministration of different medicinal plant extracts(curcumin and extracts of Nigella sativa L.[***,Jia Hei Zhong Cao],Zingiber officinale Rosc.[***,Sheng Jiang],and Punica granatum L.[***,Shi Liu])with spiramycin(SP)against the cystogenic mE-49 Toxoplasma gondii(***)strain in immunocompromised ***:We utilized 68 mice categorized into 8 groups:2 non-infected controls(immunocompetent and immunocompromised),1 infected control,and 5 infected and treated *** the experiment,the cerebral tissues of each mouse underwent parasitological,histopathological,and immunohistochemical ***:Compared with the infected non-treated group,all infected treated groups showed significant reductions in brain cyst numbers(all Pmbination(G8).Only G8 showed a significant reduction in mouse deaths compared with the other *** regards to restoring histopathological changes and decreasing inflammation,the groups infected and treated with curcumin and *** combined with SP showed the best results(Pmbinations of curcumin and extracts of *** and *** with SP signif-icantly restored the cerebral expression of caspase-3 compared with the *** extract combination(Pmpared with the local expression in the negative control ***:Our study revealed that the coadministration of *** extract with SP was the most effective combination against chronic cerebral toxoplasmosis.

关键词： medicinal plants Toxoplasma gondii mE-49 Punica granatum L Cerebral caspase-3

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沙特阿拉伯鲜乳和发酵乳中乳酸菌的分离、分子特征和益生菌潜力的研究

沙特阿拉伯鲜乳和发酵乳中乳酸菌的分离、分子特征和益生菌潜力的...

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中国畜牧兽医学会动物微生态学分会第五届第十三次全国学术研讨会

作者： maged S.Bin masalam Ahmed Bahieldin mona G.Alharbi Saad Al-masaudi soad K.Al-Jaouni Steve m.Harakeh Rashad R.Al-Hindi 白海武如娟香红星 Department of Biology Faculty of ScienceKing Abdulaziz University Department of Pediatric Hematology/Oncology Yousef Abdullatif Jameel Chair of Prophetic Medicine ApplicationKing Abdulaziz University HospitalFaculty of Medicine

益生菌对人体胃肠道有益,乳酸菌(LAB)广泛分布于自然界,并在食品工业中得到了充分利用,是益生菌的侯选细菌。本研究目的从沙特阿拉伯国家的某牧场生产的鲜乳和发酵乳中分离乳酸菌和研究其特征。结果,从13种不同的鲜乳和发酵乳分离得到9... 详细信息

益生菌对人体胃肠道有益,乳酸菌(LAB)广泛分布于自然界,并在食品工业中得到了充分利用,是益生菌的侯选细菌。本研究目的从沙特阿拉伯国家的某牧场生产的鲜乳和发酵乳中分离乳酸菌和研究其特征。结果,从13种不同的鲜乳和发酵乳分离得到93株疑似乳酸菌。基于16S rDNA基因序列比较并分析其遗传相关性,鉴定了46株乳酸菌。没有一株乳酸菌表现出对临床相关抗生素的抗性或有任何溶血活性,但它们的益生菌特性表现不一,即对pH的耐受性、对胆汁的抗性和抗菌活性。结果表明,分离得到的干酪乳杆菌mSJ1(Lactobacillus casei),干酪乳杆菌Dwan5,植物乳杆菌EyLan2(Lactobacillus plantarum)和屎肠球菌Gail-BawZir8(Enterococcus faecium)最有可能成为有益生菌潜力的最好菌株。我们推测菌种组合的协同作用可以发挥更有效的益生菌的潜力。来自沙特阿拉伯的生鲜乳和发酵乳产品,特别是由骆驼奶制成的发酵奶制品Laban,富含乳酸菌LAB,具有很好的益生菌潜力。

关键词：鲜乳发酵乳分离鉴定益生菌沙特阿拉伯

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