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CT Thresholds for Spinal Bone Mineral Attenuation to Prioritize Eligible Older Women for Osteoporosis Screening

Open Journal of Radiology 2024年第2期14卷 92-101页

作者： Seo yeon K. Orite Bryn Higuchi Hyo-Chun yoon Lana H. Gimber St. Elizabeths Medical Center Brighton MA USA University of California Irvine CA USA Kaiser Permanente Division of Research Oakland CA USA Department of Diagnostic Imaging Hawaii Permanente Medical Group Honolulu HI USA

Introduction: Computed tomography (CT) measurements of bone mineral attenuation may be a useful means to identify older women who should be prioritized for bone mineral density screening. Methods: We compared bone mineral attenuation as measured in the L1 vertebra of CT studies to the results of dual-energy x-ray absorptiometry (DEXA) studies to determine what CT attenuation thresholds might yield a reasonable combination of sensitivity and specificity for the detection of osteoporosis. The study was limited to women between the ages of 65 and 75 years who had a DEXA study and a CT that included the L1 or adjacent vertebra performed within 3 years of the DEXA study. Results: There were 1226 women in this study, of whom 452 (38%) had osteoporosis based on a T-score ≤ −2.5 by DEXA. There were 830 CT studies performed with contrast and 396 studies which were performed without contrast. There was a statistically significant difference in the mean HU of those studies performed without contrast compared to those with contrast (unenhanced mean 103 HU versus 125 HU, p < 0.001). Different CT attenuation thresholds provided the most appropriate combination of sensitivity and specificity for the detection of osteoporosis when comparing CT studies performed without or with IV contrast and when all the CT data were used in aggregate. Conclusion: Different thresholds appear necessary when using the mean CT vertebral attenuation to identify older women for preferential referral for DEXA studies.

关键词： Osteoporosis Bone Mineral Attenuation CT Threshold

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Embolization of pancreatic arteriovenous malformation:A case report

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World Journal of Clinical Cases 2020年第8期8卷 1471-1476页

作者： so yeon yoon Gyeong Sik Jeon Shin Jae Lee Dae Joong Kim Chang Il Kwon Mi Hyun Park Department of Radiology CHA Bundang Medical CenterCollege of MedicineCHA UniversitySeongnam-si 13496Gyeonggi-doSouth Korea Department of Radiology Research Institute of Radiological ScienceYongin Severance HospitalYonsei University College of MedicineYongin-si 17046South Korea Department of Internal Medicine Digestive Disease CenterCHA Bundang Medical CenterCollege of MedicineCHA UniversitySeongnam-si 13496Gyeonggi-doSouth Korea Department of Radiology Dankook University HospitalChungcheongnam-do 31116South Korea

BACKGROUND Pancreatic arteriovenous malformation(AVM)is a rare disease with a number of different reported treatment methods,but there are as yet no established or definite treatments for the disease.CASE SUMMARY A 43-year-old man visited the hospital due to periumbilical pain.The patient underwent imaging study and laboratory testing for evaluation of cause.Pancreatic AVM associated with pancreatitis was suspected on computed tomography and magnetic resonance imaging.The patient was diagnosed with pancreatic AVM with pancreatitis on imaging study and angiography.Transcatheter arterial embolization with various embolic materials was performed.Follow-up computed tomography scan revealed progressive regression of AVM and improvement of pancreatitis.At two-year follow-up,the patient showed no recurrence of symptom or pancreatitis.CONCLUSION Transcatheter arterial embolization can be considered an effective treatment modality for selective cases of pancreatic AVM.

关键词： Pancreas Arteriovenous malformation Pancreatitis Pancreatic pseudocyst Embolization Therapeutic Case report

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Temporary severe oculomotor nerve palsy after reconstruction of orbital medial wall fracture: a case report of nonfamiliar complication

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International Journal of Ophthalmology(English edition) 2022年第6期15卷 1032-1034页

作者： yeon Woong Chung Tae yoon La Department of Ophthalmology St.Vincent's HospitalCollege of Medicinethe Catholic University of KoreaSuwon 16247Republic of Korea

Dear Editor, Commonly known complications following reconstruction of an orbital fracture include diplopia, hemorrhage, and displacement or infection of the orbital implant, and some studies have reported ptosis cause... 详细信息

关键词： fracture orbital dip

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A case of unsuspected trans-orbital-cranial penetrating injury by a wooden chopstick in a one-year-old infant

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International Journal of Ophthalmology(English edition) 2022年第3期15卷 523-526页

作者： yeon Woong Chung soon Young Lee Tae yoon La Department of Ophthalmology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 16247Korea

Dear Editor,Transorbital penetrating injury is one emergency faced by ophthalmologists during primary care that requires special attention because it can lead to serious ophthalmic and neurological sequela.Of all head injuries, intracranial penetrating injuries occur at a low rate of 0.4%[1], and transorbital-cranial penetrating injuries are even more rare, but do occur more frequently in young children than in adults[2-3].

关键词： injuries infant orbital

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Lemierre's syndrome caused by Klebsiella pneumoniae:A case report

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World Journal of Nephrology 2021年第5期10卷 101-108页

作者： so yeon Hwang Seok Joon Shin Hye Eun yoon Department of Internal Medicine Incheon St.Mary's HospitalCollege of MedicineThe Catholic University of KoreaIncheon 21431South Korea

BACKGROUND Lemierre's syndrome is a disease that causes anaerobic sepsis,internal jugular vein thrombosis,and septic embolism in the lungs and other organs after acute oropharyngeal infection.It was named after André-Alfred Lemierre in 1936.CASE SUMMARY Here,we have reported a case of Lemierre’s syndrome in a 56-year-old female patient who presented with a sore throat.The patient had septic shock,had not voided,and had severe hyperglycemia at the time of her visit.Imaging tests revealed bilateral pneumonia,pleural effusion,pulmonary embolism,and renal vein thrombosis.The patient was admitted to the intensive care unit and placed on mechanical ventilation due to acute respiratory distress syndrome.Continuous renal replacement therapy was administered to treat renal failure with anuria.Klebsiella pneumoniae was cultured from blood and sputum samples.After reviewing various results,the patient was ultimately diagnosed with Lemierre’s syndrome.The patient was treated with appropriate antibiotics and thrombolytic agents.She was discharged from the hospital after recovery.CONCLUSION Lemierre’s syndrome is associated with a high mortality rate.Therefore,clinicians should be familiar with the signs and symptoms of this disease as well as the preemptive examinations,procedures,and treatments.

关键词： Lemierre's syndrome Klebsiella pneumoniae Diabetes Mellitus Pulmonary embolism Septic pneumonia Case report

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Humidity-induced synaptic plasticity of ZnO artificial synapses using peptide insulator for neuromorphic computing

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Journal of Materials Science & Technology 2022年第24期119卷 150-155页

作者： Min-Kyu song Hojung Lee Jeong Hyun yoon Young-Woong song Seok Daniel Namgung Taehoon Sung yoon-Sik Lee Jong-Seok Lee Ki Tae Nam Jang-yeon Kwon School of Integrated Technology Yonsei UniversityIncheon 21983South Korea Department of Materials Science and Engineering Seoul National UniversitySeoul 08826South Korea soft Foundry Seoul National UniversitySeoul 08826South Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826South Korea

Neuromorphic devices inspired by the human brain have attracted significant attention because of their excellent ability for cognitive and parallel computing.This study presents ZnO-based artificial synapses with peptide insulators for the electrical emulation of biological synapses.We demonstrated the dynamic responses of the device under various environmental conditions.The proton-conducting property of the tyrosine-rich peptide enables time-dependent responses under ambient conditions such that various aspects of synaptic behaviors are emulated by the devices.The transition from short-term memory to longterm memory is achieved via electrochemical doping of ZnO by protons.Furthermore,we demonstrate an image classification simulation using a multi-layer perceptron model to evaluate the potential of the device for use in neuromorphic computing.The neural network based on our device achieved a recognition accuracy of 87.47% for the MNIST handwritten digit images.This work proposes a novel device platform inspired by biosystems for brain-mimetic hardware systems.

关键词： Artificial synapse Neuromorphic computing Oxide semiconductor Proton conductor Artificial neural network

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Tyrosine-mediated analog resistive switching for artificial neural networks

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Nano Research 2023年第1期16卷 858-864页

作者： Min-Kyu song Seok Daniel Namgung Hojung Lee Jeong Hyun yoon Young-Woong song Kang Hee Cho yoon-Sik Lee Jong-Seok Lee Ki Tae Nam Jang-yeon Kwon School of Integrated Technology Yonsei UniversityIncheon 21983Republic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyMA 02139USA Research Laboratory of Electronics Massachusetts Institute of TechnologyMA 02139USA Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea soft Foundry Seoul National UniversitySeoul 08826Republic of Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea

The fourth industrial revolution indispensably brings explosive data processing and storage;thus,a new computing paradigm based on artificial intelligence-enabling device structure is urgently required.Memristors have received considerable attention in this regard because of their ability to process and store data at the same location.However,fundamental problems with abrupt switching characteristics limit their practical application.To address this problem,we utilized the concept of metaplasticity inspired by biosystems and observed gradual switching in the peptide-based memristor at high proton conductivity.An unexpectedly high slope value>1.7 in the logI–V curve at low voltage(≤400 mV)was considered the main origin,and it might arise from the modulatory response of proton ions on the threshold of Ag ion migration in the peptide film.With the obtained gradual switching property at high proton conductivity,the device showed significantly increased accuracy of image recognition(~82.5%).We believe that such a demonstration not only contributes to the practical application of neuromorphic devices but also expands the bioinspired functional synthetic platform.

关键词： artificial synapse neuromorphic computing proton conductor peptide materials artificial neural network

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Investigations of an Air Starting Motor of Marine Medium-Speed Diesel Engine with Numerical Analyses

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Journal of Thermal Science 2010年第2期19卷 148-153页

作者： yeon Won Lee yoon Hwan Choi Deog Hee Doh Division of Mechanical Eng. Pukyong National Univ.San 100 Division of Mechanical and Information Eng.

The marine medium-speed diesel engines are started by two methods;one is the electric motors,and the other air starting motors.Even though air starting motor is dependent of the engine types and sizes,it has been widely used in this area due to its simplicity,convenience and reliability.The purpose of this paper is to give the designing parameters in order to make a proper "Air Starting Motor" using CFD.The aerodynamic approaches were given to understand the internal flow characteristics of the air starting motor.In addition,we have carried out the investigation of effects of tip clearance.In the calculations the tip clearance of air starting motor has been varied between 0,2.8,4.3 and 5.7% of blade span.The results of computation are the tip clearance increased to 2.8%,the torque decreased 24%,and there was no more large changes when the clearances increased to 4.3% and 5.7%.

关键词：柴油发动机空中起动数值分析中速海洋空气动力学计算流体力学汽车

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Boost Up the Mechanical and Electrical Property of CNT Fibers by Governing Lyotropic Liquid Crystalline Mesophases with Aramid Polymers for Robust Lightweight Wiring Applications

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Advanced Fiber Materials 2023年第2期5卷 514-526页

作者： Ki‑Hyun Ryu Jeong‑Gil Kim Dongju Lee Seo Gyun Kim Bon‑Cheol Ku Jun yeon Hwang Kwang‑Un Jeong Nam Dong Kim Dae‑yoon Kim Functional Composite Materials Research Center Korea Institute of Science and TechnologyWanju 55324Republic of Korea Carbon Composite Materials Research Center Korea Institute of Science and TechnologyWanju 55324Republic of Korea Department of Polymer‑Nano Science and Technology Department of Nano Convergence EngineeringJeonbuk National UniversityJeonju 54896Republic of Korea Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea

Monofilament type of polyaromatic amide(PA)and carbon nanotube(CNT)composite fibers is presented.A concept of a lyotropic liquid crystal(LLC)constructed via a spontaneous self-assembly is introduced to mitigate the extremely low com-patibility between PA and CNT.These approaches provide an effective co-processing route of PA and CNT simultaneously to fabricate the uniform,continuous,and reliable composite fibers through a wet-spinning.Interestingly,the addition of a small amount PA into the dope solution of CNT governs the LLC mesophase not only in a spinneret stage but also in a coagulant region.Thus,the developed PA/CNT composite fibers have the high uniaxial orientational order and the close interfacial packing compared to the pure CNT fibers.The PA/CNT composite fibers achieve the outstanding tensile strength,electrical conductivity,and electrochemical response,while maintaining a lightweight.They also exhibit the chemical,mechanical,and thermal robustness.All of these advantages can make flexible,sewable,and washable PA/CNT composite fibers ideal nanocomposite materials for use in next-generation information and energy transporting system by replacing conventional metal electrical conductors.

关键词： Carbon nanotube Aramid polymer Liquid crystal Composite fiber Electrical wire

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Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea

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Frontiers of Medicine 2019年第6期13卷 713-722页

作者： Seo yeon Baik Hyunah Kim so Jung Yang Tong Min Kim Seung-Hwan Lee Jae Hyoung Cho Hyunyong Lee Hyeon Woo Yim Kun-Ho yoon Hun-Sung Kim Department of Medical Informatics College of MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea College of Pharmacy Sookmyung Women’s UniversitySeoul 04310Republic of Korea Division of Endocrinology and Metabolism Department of Internal MedicineSeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea Clinical Research Coordinating Center Catholic Medical CenterThe Catholic University of KoreaSeoul 06591Republic of Korea Department of Preventive Medicine College of MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea

Few long-term follow-up studies have compared the changes in renal function according to the type of statin used in Korea.We compared the long-term effects of statin intensity and type on the changes in the glomerular filtration rate(GFR).We extracted data of patients who took statin for the first time.We analyzed whether or not different statins affect the changes in GFR at 3 months after baseline and 4 years after.We included 3678 patients and analyzed the changes in GFR.The GFR decreased by 3.2%±0.4%on average 4 years after the first statin prescription,indicating statistically significant deterioration(from 83.5±0.4 mL/min/1.73 m2 to 79.9±0.4 mL/min/1.73 m2,P<0.001).When comparing the GFR among different statins,significant differences were observed between atorvastatin and fluvastatin(−5.3%±0.7%vs.1.2%±2.2%,P<0.05)and between atorvastatin and simvastatin(−5.3%±0.7%vs.−0.7%±0.8%,P<0.05).In pitavastatin(odds ratio[OR]=0.64,95%confidence interval[CI]=0.46-0.87,P<0.005)and simvastatin(OR=0.69,95%CI=0.53-0.91,P<0.008),the GFR rate that decreased by<60 mL/min/1.73 m2 was significantly lower than that of atorvastatin.Regarding long-term statin intake,GFR changed with the type of statin.This work is the first in Korea to compare each statin in terms of changes in the GFR after the statin prescription.

关键词： statin glomerular filtration rate HMG-CoA reductase inhibitor chronic kidney disease

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