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Residentia. energy tra.sition a.d chronic respira.ory disea.es

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The Innova.ion 2024年第3期5卷 33-43页

作者： Hongcheng Wei Qiurun Yu Da.rong Chen Mingzhi Zha.g Qua.qua. Gua. Bo Ha.g a.toine M.snijders a.ria. Cova.i Ya.ka. Xia Sta.e Key La.ora.ory of Reproductive Medicine a.d Offspring Hea.th Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjing 211166China Key La.ora.ory of Modern Toxicology of Ministry of Educa.ion School of Public HealthNanjing Medical UniversityNanjing 211166China The a.filia.ed Wuxi People’s Hospita. of Na.jing Medica. University Wuxi People’s HospitalWuxi Medical CenterNanjing Medical UniversityWuxi 214023China Biologica. Systems a.d Engineering Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Toxicologica. Centre University of Antwerp2610 WilrijkBelgium

Obta.ning clea. energy is of prime importa.ce for pla.eta.y hea.th a.d susta.na.le *** a.med to a.sess the a.socia.ion between residentia. energy tra.sition a.d the risk of chronic respira.ory *** da.a.from the Globa. Hea.th Observa.ory a.d Globa. Burden of Disea.es,Injuries,a.d Risk Fa.tors Study,we delinea.ed the spa.ia. distribution a.d tempora. trends of the popula.ion using clea. fuels for cooking a. a.globa. *** the China.Hea.th a.d Retirement Longitudina. Study,we performed rigorous a.d well-structured multista.e a.a.yses incorpora.ing both cross-sectiona. a.d prospective da.a.a.a.yses to exa.ine the a.socia.ions between solid fuel use,residentia. energy tra.sition,dura.ion of solid fuel use,a.d the risk of chronic respira.ory *** grea. progress,huge dispa.ities in a.cess to clea. energy persist *** energy tra.sition wa. a.socia.ed with a.lower risk of chronic respira.ory *** the period of 2011–2013,compa.ed with persistent solid fuel users,both pa.ticipa.ts who switched from solid to clea. fuels(a.justed risk ra.io[RR]0.78,95%confidence interva.[CI]0.62–0.98)a.d persistent clea. fuel users(a.justed RR 0.71,95%CI 0.57–0.89)ha. significa.tly lower risk of chronic respira.ory disea.es(pa.socia.ions were observed in the period of 2011–2015 a.d 2011–*** energy tra.sition from solid to clea. fuels could reduce the risk of chronic respira.ory *** is a.va.ua.le lesson for policy-ma.ers a.d the genera. public to a.celera.e energy switching to a.levia.e the burden of chronic respira.ory disea.es a.d a.hieve hea.th benefits,pa.ticula.ly in low-a.d middle-income countries.

关键词： cooking income globa.ly

Serum bile a.id a.d unsa.ura.ed fa.ty a.id profiles of non-a.coholic fa.ty liver disea.e in type 2 dia.etic pa.ients

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World Journa. of Dia.etes 2024年第5期15卷 898-913页

作者： Su-Su Feng Si-Jing Wa.g Lin Guo Pa.-Pa. Ma.Xia.-Long Ye Ming-Lin Pa. Bo Ha.g Jia.-Hua.Ma. a.toine M snijders Yi-Bing Lu Da.Fa.Ding Depa.tment of Endocrinology The Second Affiliated Hospital of Nanjing Medical UniversityNanjing 210011Jiangsu ProvinceChina Biologica. Systems a.d Engineering Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720United States

Ba.KGROUND The understa.ding of bile a.id(Ba.a.d unsa.ura.ed fa.ty a.id(UFa.profiles,a. well a. their dysregula.ion,rema.ns elusive in individua.s with type 2 dia.etes mellitus(T2DM)coexisting with non-a.coholic fa.ty liver disea.e(Na.LD).Investiga.ing these meta.olites could offer va.ua.le insights into the pa.hophy-siology of Na.LD in *** To identify potentia. meta.olite bioma.kers ca.a.le of distinguishing between Na.LD a.d *** a.tra.ning model wa. developed involving 399 pa.ticipa.ts,comprising 113 hea.thy controls(HCs),134 individua.s with T2DM without Na.LD,a.d 152 individua.s with T2DM a.d *** va.ida.ion encompa.sed 172 *** pa.ients were divided ba.ed on liver fibrosis *** a.a.ytica. a.proa.h employed univa.ia.e testing,orthogona. pa.tia. lea.t squa.es-discrimina.t a.a.ysis,logistic regression,receiver opera.ing cha.a.teristic curve a.a.ysis,a.d decision curve a.a.ysis to pinpoint a.d a.sess the dia.nostic va.ue of serum *** Compa.ed to HCs,both T2DM a.d Na.LD groups exhibited diminished levels of specific *** UFa.,pa.ticula. a.ids exhibited a.positive correla.ion with Na.LD risk in T2DM,while theω-6:ω-3 UFa.ra.io demonstra.ed a.nega.ive *** ofα-linolenic a.id a.dγ-linolenic a.id were linked to significa.t liver fibrosis in *** va.ida.ion cohort substa.tia.ed the predictive effica.y of these bioma.kers for a.sessing Na.LD risk in T2DM *** This study underscores the connection between a.tered Ba.a.d UFa.profiles a.d the presence of Na.LD in individua.s with T2DM,proposing their potentia. a. bioma.kers in the pa.hogenesis of Na.LD.

关键词： Bile a.id Non-a.coholic fa.ty liver disea.e Type 2 dia.etes mellitus Unsa.ura.ed fa.ty a.id

Journa. of Hepa.ology|硫唑嘌呤与吗替麦考酚酯诱导初治自身免疫性肝炎缓解的开放标签随机对照试验

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临床肝胆病杂志 2024年第5期40卷 342-342页

作者：李想季慧范吉林大学第一医院感染病与病原生物学中心肝胆胰内科

自身免疫性肝炎(a.H)患者可能需要终身免疫抑制治疗。目前泼尼松龙和硫唑嘌呤联合治疗的效果和耐受性令人担忧。吗替麦考酚酯(MMF)已成为一种替代选择。来自荷兰拉德堡德大学的snijders等进行了一项研究,目的是比较MMF和硫唑嘌呤在a.H... 详细信息

自身免疫性肝炎(a.H)患者可能需要终身免疫抑制治疗。目前泼尼松龙和硫唑嘌呤联合治疗的效果和耐受性令人担忧。吗替麦考酚酯(MMF)已成为一种替代选择。来自荷兰拉德堡德大学的snijders等进行了一项研究,目的是比较MMF和硫唑嘌呤在a.H诱导治疗中的效果。在这项为期24周的前瞻性、随机、开放标签、多中心优效性试验中,70例未经治疗的a.H患者接受了MMF或硫唑嘌呤联合泼尼松龙治疗。主要终点是生化缓解,定义为治疗24周后血清a.T和IgG水平恢复正常.

关键词：自身免疫性肝炎免疫抑制治疗硫唑嘌呤诱导治疗 a.H 优效性泼尼松龙吗替麦考酚酯

Nonlinea. Optica. Properties of Tri-nuclea. Tra.sition Meta. Clusters M-(μ-S)s-M'(M=Mo,W;M'=Cu,a.,a.)

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Chinese Chemica. Letters 2002年第9期13卷 893-896页

作者： XiHua.HEN Ja.pG.snijders 等 Fujia.InstituteofResea.chontheStructureofMa.ter ChineseAcademyofSciencesStateKeyLaboratoryofStructuralChemistryFuzhouFujian350002 Theoretica.ChemistryGroup MaterialsScienceC

The sta.ic pola.iza.ilities a.d the second-order hyperpola.iza.ilities of a.series of tri-nuclea. meta. cluster models MS4(MPPh3)2(MPPh3) (M=Mo,W; M=Cu, a., a.) ha.e been ca.cula.ed within the first-principle theoretica. fra.ework. The model clusters ha.e two fra.ments of rhombic units a.d it is the cha.ge tra.sfer from one of these moieties to the other tha. is responsible for nonlinea. optica. property. This kind of electronic deloca.iza.ion, differentia.ed from tha. of pla.a. p-system, is very interesting a.d is worthy for further investiga.ion.

关键词： Tra.sition meta. cluster nonlinea. optica. property finite-field a.proa.h density functiona. theory method.

Photometric Studies of EV Cnc a.d a. Cnc in the Open Cluster M67

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Resea.ch in a.tronomy a.d a.trophysics 2024年第8期24卷 196-211页

作者： Ma.a.ha.Ra.i G. K.Srira. Deblina.La.iri Vija.a.a. Depa.tment of a.tronomy Osmania UniversityHyderabad 500007India

Conta.t bina.ies a. va.ious sta.es of evolution unveil va.ious opera.ing mecha.isms tha. drive *** report the photometric a.d period va.ia.ion a.a.ysis of two conta.t bina.ies EV Cnc a.d a. Cnc in open cluster *** observed the cluster from the JCBT 1.3 m telescope a.d utilized TESS a.d Kepler *** photometric solutions of EV Cnc a.d a. Cnc revea.ed a.ma.s ra.io of q~0.41 a.d~0.15 with a. inclina.ion of i=42°a.d87°*** solutions suggest tha. EV Cnc is proba.ly a.semi-deta.hed a.d a. Cnc is a.deep low-ma.s ra.io conta.t *** study of O-C va.ia.ion a.a.ysis indica.es tha. for both systems,the period is increa.ing which suggests the ma.s tra.sfer is occurring from seconda.y to *** the ca.e of a. Cnc a.d ba.ed on simula.ions by ra.domly va.ying the time of minima.to fit the LITE solution,we noted the third body orbita. period to be a.ound P_(3)=26.82±2.54 yr,which is different from ea.lier reported va.ues a.d conclude tha. future observa.ions a.e required to confirm this *** compa.e these two systems with other simila. conta.t bina.ies to get a. estima.e of the fina. configura.ion of the respective systems.

关键词： (sta.s)bina.ies(including multiple) close-(sta.s)bina.ies eclipsing-sta.s a.tivity

The Difficult Pa.h from Perception to Preca.tiona.y a.tion-Pa.ticipa.ory Modeling a. a.Pra.tica. Tool to Overcome the Risk Perception Pa.a.ox in Flood Prepa.edness

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Interna.iona. Journa. of Disa.ter Risk Science 2018年第4期9卷 472-485页

作者： Gisela.Wa.hinger Pa.rick keilholz Cora. O’Bria. DIa.OGIK GmbH 70176 StuttgartGermany DHI Wa.Y GmbH 81671 MunichGermany

The risk perception pa.a.ox illustra.es the perception of na.ura. ha.a.ds a. not directly rela.ed to a.willingness to a.t or enga.e in preca.tiona.y beha.ior. Yet the utiliza.ion of pa.ticipa.ory processes ca. help to overcome this ga.. In a.pra.tica. exa.ple in the wa.ershed of the Da.ube River a.d its contributing strea.s in Germa.y,we a.med to solve questions a.out the va.ue of pa.ticipa.ory modeling a. a.method to bridge the ga. linked to flood polder pla.ning a.d a.reloca.ion of a.dike for protection a.a.nst high floods(centennia. floods a.d ra.er). Loca. communities, citizen initia.ives, a.d nongovernmenta. environmenta. orga.iza.ions joined together for round ta.le discussions initia.ed by the wa.er ma.a.ement a.thorities. a.pa.ticipa.ory modeling process ena.led these diverse sta.eholders to enga.e with the experts who built the groundwa.er models for the pla.ning process. a. pa.t of this study, two ca.e studies a.e presented. In the first exa.ple, neutra. media.ors a.sisted the round ta.le ‘‘Flood Polder Ka.za.(Da.ube)'' in order to cultiva.e mutua. trust a.d understa.ding between the a.thorities a.d the former opponents of the project. This process is still ongoing,cha.lenged by long-term pla.ning a.d the more immedia.e obsta.le of current politica. cha.ges. The second ca.e studyis loca.ed on the river a.z, a.tributa.y of the river Inn,which flows into the Da.ube, where the reloca.ion of a.dike wa. pla.ned. This a.ticle demonstra.es how pa.ticipa.ory modeling contributes to bridging the ga. between a.loca. resident's risk perception a.d rea. a.tion in the ca.e of flood prepa.edness.

关键词： Ba.a.ia Flood ha.a.d Flood perception Flood risk Germa.y Pa.ticipa.ory modeling Preca.tiona.y a.tion

Kerogen Kinetic Distributions a.d Simula.ions Provide Insights into Petroleum Tra.sforma.ion Fra.tion (TF) Profiles of Orga.ic-Rich Sha.es

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Journa. of Ea.th Science 2024年第3期35卷 747-757页

作者： Da.id a.Wood DWa.Energy Limited Lincoln LN59JPUnited Kingdom

Two hundred a.d fifty single first-order a.rhenius rea.tions a.e simula.ed to genera.e S2 pyrogra.s a. three hea.ing ra.es 25,15,a.d 5°C·*** a.tiva.ion energy(E)a.d pre-exponentia. fa.tor(a.of the rea.tions simula.ed follow a.long-esta.lished trend of those va.ia.le va.ues displa.ed by sha.es a.d *** cha.a.teristics of the tra.sforma.ion fra.tion(TF)profiles(product genera.ion window tempera.ures)of the simula.ed single rea.tions a.e compa.ed to the TF profiles of recorded sha.e pyrogra.s genera.ed by multiple rea.tions with different E-a.va.ues lying nea. the defined E-a.*** simila.ities a.d differences a.e observed between the TF profile va.ues of the two *** simila.ities support the sprea. of E-a.va.ues involved in sha.e pyrogra. best *** differences a.e most likely expla.ned by the complexity of the multiple kerogen first-order a.d second-order rea.tions contributing to the recorded sha.e pyrogra.s versus the simplicity a.d crispness of the single first-order rea.tions *** results a.so justify the va.idity of using the previously described“va.ia.le E-a.pyrogra.-fitting method”of multi-hea.ing-ra.e sha.e pyrogra.s ena.ling optimizers to choose multiple rea.tions from a. unlimited ra.ge of E-a.*** contra.t,further doubt is ca.t on the va.idity of the consta.t-a.pyrogra.-fitting method used by the Ea.y%Ro technique,in tha. a.distribution of rea.tions with a.single a.va.ue is unlikely to represent the complex va.iety of kerogen ma.era.s observed in sha.e *** profiles genera.ed by the va.ia.le E-a.pyrogra.-fitting method lie close to the esta.lished E-a.trend a.d a.e likely to provide more rea.istic TF genera.ion window tempera.ures tha. TF profiles genera.ed by the consta.t-a.pyrogra.-fitting method.

关键词： tra.sforma.ion fra.tion profiles simula.ed S2 pyrogra.s multiple hea.ing ra.es kerogen/sha.e kinetics S2 pyrogra. fitting techniques kerogen petroleum resea.ch.

Rodent biology a.d ecologica.ly ba.ed rodent ma.a.ement(EBRM)-25 yea.s of progress through promoting multidisciplina.y resea.ch

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Integra.ive Zoology 2024年第1期19卷 2-7页

作者： Gra.t R. SINGLETON Lyn a. HINDS Rhodes Ma.UNDI Steven R. BELMa.N Na.ura. Resources Institute University of Greenwich Kent UK CSIRO Hea.th a.d Biosecurity Canberra ACT Australia a.rica. Centre of Excellence for Innova.ive Rodent Pest Ma.a.ement a.d Biosensor Technology Development Sokoine University of Agriculture Morogoro Tanzania Institute of Pest Ma.a.ement Sokoine University of Agriculture Morogoro Tanzania

“During rodent outbrea. yea.s in ea.tern a.rica.lo-ca.ly,more tha. 80%of the potentia. ha.vest ma. be lost,but even in non-outbrea. periods,rodents ca.se chronic da.a.e to crops….The pest rodent story in a.rica.in-volves severa. species embedded in a.broa. a.d va.ia.le la.dsca.e with highly va.ia.le densities.”(Leirs et a..2010).

关键词： da.a.e crops

First-principles ca.cula.ions to investiga.e structura.,electronic,ma.netic,optica. a.d thermodyna.ic properties of RE_(2)Rh_(3)Ge(RE=Pr,Sm)

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Journa. of Ra.e Ea.ths 2024年第7期42卷 1385-1393,I0007页

作者： a.Eza.er R.Ma.rour M.Ha.edoun J.Kha.ba.h a.Rezzouk a.Hourma.a.la. N.Benza.our K.Bouslykha.e La.ora.ory of Solid Physics Faculty of Sciences Dhar El MehrazSidi Mohamed Ben Abdellah UniversityBP 1796FezMorocco Equipe de Physique du Solide LaboratoiresLIPIEcole Normale SupérieureBensoudaFèsMorocco

In this pa.er,we a.a.yzed the physica. cha.a.teristics of the terna.y a.loys RE_(2)Rh_(3)Ge(RE=Pr a.d Sm)using the first principles ca.cula.ion ba.ed on functiona. density theory integra.ed in the Wien2k *** ca.cula.ed forma.ion energies of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e−5.3827 a.d−5.2782 eV/a.om,respectively,showing tha. these a.loys ma. exist *** results of the ba.d structure a.d density of sta.es indica.e tha. a.l of the compounds tested a.e ma.netic meta.s,a.d their ma.netism is mostly rela.ed to the contribution of Pr a.d Sm *** tota. ma.netic moments of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e 4.07245 a.d 11.16161μB/f.u,*** pa.a.eters such a. hea. ca.a.ity a. consta.t pressure,entropy,Debye tempera.ure,la.tice volume,compressibility coefficients,a.d Grüneisen pa.a.eter a.loys were ca.cula.ed using the Gibbs a.gorithm a.d studied in depth over a.la.ge tempera.ure ra.ge of 0-900 *** Debye tempera.ure increa.es with increa.ing pressure a.d decrea.es with decrea.ing ***,the Debye tempera.ures ca.cula.ed a. p=0 GPa.a.d T=300 K a.e equa. to be 342 a.d 322 K for Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge,*** optica. cha.a.teristics such a. the rea. a.d ima.ina.y portions of the dielectric function,the a.sorption coefficient,the energy-loss function,a.d the refra.tive index were investiga.ed a.d discussed in more depth.

关键词： Ma.netic meta.s Functiona. density theory Density of sta.es Ma.netic moment Optica. a.d thermodyna.ic properties Ra.e ea.ths