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中国临床研究 2024年第7期37卷 1109-1112,1119页

作者：孙蕴怡孟雅婧阳雨露沈聃琳王道锦肖洪奇李青 smruthi mohan 邱昌建四川大学华西医院心理卫生中心四川成都610044 四川大学华西临床医学院四川成都610044

近几年来重复经颅磁刺激(rTMS)治疗在幻听症状的临床应用研究上取得了较大进展。近期研究发现经颅磁刺激(TMS)某些特定的刺激模式和刺激靶点对精神分裂症患者的幻听症状有一定改善,一般认为优先选择靶点如颞顶区和背外侧前额叶区。低频... 详细信息

近几年来重复经颅磁刺激(rTMS)治疗在幻听症状的临床应用研究上取得了较大进展。近期研究发现经颅磁刺激(TMS)某些特定的刺激模式和刺激靶点对精神分裂症患者的幻听症状有一定改善,一般认为优先选择靶点如颞顶区和背外侧前额叶区。低频刺激左颞顶交界区(TPJ)皮质是辅助治疗言语性幻听(AVH)的主要选择,疗效相对明确。然而,目前缺少大样本随机对照试验(RCT)等循证医学证据,以及对TMS的疗效缺乏客观有力的评估工具,rTMS对幻听症状的临床应用仍处于观望状态。本文从rTMS治疗AVH的刺激靶点、连续性θ短阵快速脉冲、rTMS治疗AVH的增强方案和深部TMS等方面对近年TMS治疗AVH的研究进展进行综述,以期推动临床对rTMS在干预幻听症状方面的认识,为未来进行大样本的RCT、建立客观的疗效评估方式等循证医学证据提供研究方向。

关键词：经颅磁刺激幻听低频经颅磁刺激颞顶交界区 θ短阵快速脉冲

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Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

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四川生理科学杂志 2022年第6期44卷 1118-1118页

作者： smruthi Karthikeyan Department of Pediatrics University of California San Diego La Jolla CA USA Department of Biomedical Informatics University of California San Diego La Jolla California USA Department of Computer Science and Engineering University of California San Diego La Jolla CA USA Department of Bioengineering University of California San Diego La Jolla CA USA Department of Immunology and Microbiology The Scripps Research Institute La Jolla CA USA Expedited COVID Identification Environment (EXCITE) Laboratory Department of Pediatrics University of California San Diego La Jolla CA USA Department of Obstetrics Gynecology and Reproductive Sciences University of California San Diego La Jolla CA USA COVID-19 Detection Investigation Surveillance Clinical and Outbreak Response California Department of Public Health Richmond CA USA Sanford Consortium of Regenerative Medicine University of California San Diego La Jolla CA USA Department of Cellular and Molecular Medicine University of California San Diego La Jolla CA USA Student Health and Well-Being University of California San Diego La Jolla CA USA Center for Computational Biology and Bioinformatics University of California San Diego La Jolla CA USA Institute for Genomic Medicine University of California San Diego La Jolla CA USA Operational Strategic Initiatives University of California San Diego La Jolla CA USA Return to Learn University of California San Diego La Jolla CA USA Student Affairs University of California San Diego La Jolla CA USA Academic Affairs University of California San Diego La Jolla CA USA Department of Pathology University of California San Diego La Jolla CA USA Scripps Health San Diego La Jolla CA USA Rady Children’s Institute for Genomic Medicine San Diego CA USA Sharp Healthcare San Diego CA USA Helix San Mateo CA USA County of San Diego Health and Human Services Agency San Diego CA USA Herbert Wertheim School of Public Health and Human Longevity Science Univers

As SARS-CoV-2 continues to spread and evolve,detecting emerging variants early is critical for public health *** lineage prevalence by clinical testing is infeasible at scale,especially in areas with limited resources,participation,or testing/sequencing capacity,which can also introduce ***-CoV-2 RNA concentration in wastewater successfully tracks regional infection dynamics and provides less biased abundance estimates than clinical testing4,*** virus genomic sequences in wastewater would improve community prevalence estimates and detect emerging variants.

关键词： wastewater Wastewater testing

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Soil algae enzymes and their biotechnological applications

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Systems Microbiology and Biomanufacturing 2022年第4期2卷 589-606页

作者： Mohammad Amin Shoarnaghavi Arti Mishra Arian Amirifar smruthi Sagarika Mahapatra Khatereh Nobaharan Arash Hemati Behnam Asgari Lajayer Tess Astatkie Department of Biology Islamic Azad University of UrmiaUrmiaIran Amity Institute of Microbial Technology Amity UniversityNoidaUttar Pradesh 201303India Indira Gandhi Agricultural University RaipurChhattisgarh 492012India 12/9 Browns Avenue RingwoodMelbourneVIC 3134Australia Department of Soil Science Faculty of AgricultureUniversity of TabrizTabrizIran Faculty of Agriculture Dalhousie UniversityTruroNS B2N 5E3Canada

At present time,most of the enzymes are derived from biological sources,including plants,animals,microalgae,algae,and other *** enzymes,among the others,account for the biggest part of application and demand in *** enzymes from soil microorganisms are very essential not only for soil fertility but also for biotechnological *** enzymes from microalage,comprising Amylase,Carbonic anhydrase,Galactosidase,Laccase,L-Asparaginase,Lipase,Peroxidase,Phytase,Protease,and Superoxide dismutase attract a considerable amount of attention for themselves in various *** of the enzymes mentioned above have a great potential for their application in biotechnology and *** of such enzymes are known for their versatility and countless applications in various fields;thus,performing research on these enzymes in the future would be *** review paper presents an overview of the potential of soil algae enzymes in fields like biotechnology,medicine and agriculture,and also provides areas for advancement in researches related to this field.

关键词： Soil algae Microalgae Enzymes Biotechnological applications

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Rice straw recycling: A sustainable approach for ensuring environmental quality and economic security

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Pedosphere 2023年第1期33卷 34-48页

作者： Anjani KUMAR Amaresh Kumar NAYAK Sandeep SHARMA Ansuman SENAPATI Debasis MITRA Bipasa mohanTY Seenichamy Rathinam PRABHUKARTHIKEYAN Kuttalingam Gopalasubramanian SABARINATHAN Indra MANI Rajendra Singh GARHWAL Sugitha THANKAPPAN Mahapatra smruthi SAGARIKA Sergio DE LOS SANTOS-VILLALOBOS Periyasamy PANNEERSELVAM Crop Production Division Indian Council of Agricultural Research(ICAR)-National Rice Research InstituteCuttackOdisha 753006India Department of Soil Science Punjab Agricultural UniversityPunjab 141027India Department of Plant Pathology Agricultural College and Research InstituteTamil Nadu Agricultural UniversityKillikulamTuticorin 628252India Division of Agricultural Engineering ICAR-Indian Agricultural Research InstitutePusaNew Delhi 110012India Collage of Agriculture Chaudhary Charan Singh Haryana Agriculture UniversityHisarHaryana 125004India School of Agriculture and Biosciences Karunya Institute of Technology and SciencesCoimbatoreTamil Nadu 641141India Laboratorio de Biotecnología del Recurso Microbiano Instituto Tecnológico De SonoraSonora 85000México

One of the major challenges in Asian countries is the effective management of rice *** ensure food security for their ever-growing population,Asian countries grow more rice,leading to increasing rice straw *** of rice straw,a common practice,is detrimental to both environmental and human ***,if managed effectively,rice straw has the potential to safeguard the sustainability of agricultural ecosystems and to uplift the economic security of the population depending on rice *** management of rice straw involving minimum soil disturbance along with retention of residues alters the soil carbon cycle through reduced carbon emissions and increased levels of total soil organic *** alternative uses of rice straw,such as production of livestock feed,bioethanol,biochar,biogas,electricity,mushroom,and paper,can add prosperity to rice farmers’life by fetching extra *** is evident that efficient management of rice straw is of enormous economic ***,it is essential to create awareness among the different rice stakeholders of these alternative economic avenues associated with rice *** review is an attempt to provide effective options for sustainable rice straw management and rice straw value chains for harnessing its economic *** further identifies gaps in our understanding of the effects of rice straw on ecological sustainability,particularly concerning the multifaceted connections between the diverse mechanisms of rice agro-ecosystems,which may greatly influence food security in the 21st century.

关键词： microorganism residue management rice straw burning rotation tillage value addition

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