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International Journal of Extreme Manufacturing 2024年第2期6卷 325-376页

作者： Guohua Zhang Ming Huang Gangli Chen Jiasheng Li Yang Liu Jianguo He Yueqing Zheng siwei tang Hailong Cui Institute of Machinery Manufacturing Technology China Academy of Engineering PhysicsMianyangSichuan 621999People’s Republic of China

Fluid lubricated bearings have been widely adopted as support components for high-end equipment in metrology,semiconductor devices,aviation,strategic defense,ultraprecision manufacturing,medical treatment,and power generation.In all these applications,the equipment must deliver extreme working performances such as ultraprecise movement,ultrahigh rotation speed,ultraheavy bearing loads,ultrahigh environmental temperatures,strong radiation resistance,and high vacuum operation,which have challenged the design and optimization of reliable fluid lubricated bearings.Breakthrough of any related bottlenecks will promote the development course of high-end equipment.To promote the advancement of high-end equipment,this paper reviews the design and optimization of fluid lubricated bearings operated at typical extreme working performances,targeting the realization of extreme working performances,current challenges and solutions,underlying deficiencies,and promising developmental directions.This paper can guide the selection of suitable fluid lubricated bearings and optimize their structures to meet their required working performances.

关键词： fluid lubricated bearings structural design performance optimization extreme working performances

Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

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Signal Transduction and Targeted Therapy 2024年第2期9卷 766-781页

作者： Lei Zhang Jiabing Chen Xiaoying Yang Chuangpeng Shen Jiawen Huang Dong Zhang Naihua Liu Chaonan Liu Yadi Zhong Yingjian Chen Kaijia tang Jingyi Guo Tianqi Cui siwei Duan Jiayu Li Shangyi Huang Huafeng Pan Huabing Zhang Xiaoqiang tang Yongsheng Chang Yong Gao State Key Laboratory of Traditional Chinese Medicine Syndrome Science and Technology Innovation CenterGuangzhou University of Chinese MedicineGuangzhouChina Key Laboratory of Immune Microenvironment and Disease(Ministry of Education) Tianjin Key Laboratory of Cellular Homeostasis and DiseaseDepartment of Physiology and PathophysiologyTianjin Medical UniversityTianjinChina Jiangsu Key Laboratory of Immunity and Metabolism Department of Pathogen Biology and ImmunologyJiangsu International Laboratory of Immunity and MetabolismXuzhou Medical UniversityXuzhouChina Department of Endocrinology The First Clinical CollegeGuangzhou University of Chinese MedicineGuangdongChina The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine ShenzhenChina Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor Nanjing University of Chinese MedicineNanjingChina Department of Biochemistry and Molecular Biology Metabolic Disease Research CenterSchool of Basic MedicineAnhui Medical UniversityHefeiChina Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE State Key Laboratory of BiotherapyWest China Second University HospitalSichuan UniversityChengduChina

A lasting imbalance between fatty acid synthesis and consumption leads to non-alcoholic fatty liver disease(NAFLD),coupled with hepatitis and insulin resistance.Yet the details of the underlying mechanisms are not fully understood.Here,we unraveled that the expression of the transcription factor Zbtb18 is markedly decreased in the livers of both patients and murine models of NAFLD.Hepatic Zbtb18 knockout promoted NAFLD features like impaired energy expenditure and fatty acid oxidation(FAO),and induced insulin resistance.Conversely,hepatic Zbtb18 overexpression alleviated hepato-steatosis,insulin resistance,and hyperglycemia in mice fed on a high-fat diet(HFD)or in diabetic mice.Notably,in vitro and in vivo mechanistic studies revealed that Zbtb18 transcriptional activation of Farnesoid X receptor(FXR)mediated FAO and Clathrin Heavy Chain(CLTC)protein hinders NLRP3 inflammasome activity.This key mechanism by which hepatocyte’s Zbtb18 expression alleviates NAFLD and consequent liver fibrosis was further verified by FXR’s deletion and forced expression in mice and cultured mouse primary hepatocytes(MPHs).Moreover,CLTC deletion significantly abrogated the hepatic Zbtb18 overexpression-driven inhibition of NLRP3 inflammasome activity in macrophages.Altogether,Zbtb18 transcriptionally activates the FXR-mediated FAO and CLTC expression,which inhibits NLRP3 inflammasome’s activity alleviating inflammatory stress and insulin resistance,representing an attractive remedy for hepatic steatosis and fibrosis.

关键词： hepatic Hepatic impaired

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抗战时期重庆三大管弦乐团研究

音乐研究 2024年第2期 48-54,I0011,I0012,55-59,F0003页

作者：汤斯惟重庆师范大学音乐学院中国抗战音乐文化研究中心

全面抗战爆发后,重庆成为中国政治、经济、军事及文化的中心。1940年,中华交响乐团、国立音乐院实验管弦乐团和国立实验剧院管弦乐团在重庆成立,近代中国管弦乐迎来了新的发展。对抗战时期在重庆成立的三大管弦乐团进行整体性的研究可... 详细信息

全面抗战爆发后,重庆成为中国政治、经济、军事及文化的中心。1940年,中华交响乐团、国立音乐院实验管弦乐团和国立实验剧院管弦乐团在重庆成立,近代中国管弦乐迎来了新的发展。对抗战时期在重庆成立的三大管弦乐团进行整体性的研究可揭开近代中国交响音乐史的时代面貌。

关键词：抗战时期重庆管弦乐团交响乐

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抗战大后方音乐研究论纲

中国音乐学 2024年第2期 101-110页

作者：汤斯惟重庆师范大学音乐学院中国抗战音乐文化研究中心

抗战大后方音乐形成于全民族抗日战争这一特殊历史时期和特定的地域,是中国近现代音乐史的重要组成部分。本文拟从抗战大后方音乐的兴起与发展、主题与主线、传承与创新、作用与影响四个方面,将大后方音乐纳入20世纪30年代初至40年代后... 详细信息

抗战大后方音乐形成于全民族抗日战争这一特殊历史时期和特定的地域,是中国近现代音乐史的重要组成部分。本文拟从抗战大后方音乐的兴起与发展、主题与主线、传承与创新、作用与影响四个方面,将大后方音乐纳入20世纪30年代初至40年代后期的政治形势、音乐现象、文化活动的纵向历史发展与横向互动中,全方位、多层次、客观真实地展现大后方音乐新格局及其历史全貌,进而深化对抗战音乐史和近现代音乐史的认识。

关键词：抗战时期大后方音乐近现代音乐

Talbot effect in anti-PT symmetric synthetic photonic lattices

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Chinese Optics Letters 2024年第3期22卷 107-111页

作者：刘兆峰唐思维温增润高垣梅蔡阳健郑立仁 Shandong Provincial Engineering and Technical Center of Light Manipulations&Shandong Provincial Key Laboratory of Optics and Photonic Device School of Physics and ElectronicsShandong Normal UniversityJinan 250358China School of Physical Science and Technology Soochow UniversitySuzhou 215006China

We investigated the Talbot effect in an anti-parity-time(PT)symmetric synthetic photonic lattice composed of two coupled fiber loops.We calculated the band structures and found that with an increase in the gain-loss parameter,the band transitions from a real spectrum to a complex spectrum.We study the influence of phase in the Hermitian operator on the Talbot effect,and the Talbot effect disappears when the period of the input field is N>8.Further study shows that the variation of Talbot distance can also be modulated by non-Hermitian coefficients of gain and loss.This work may find significant applications in pulse repetition-rate multiplication,temporal invisibility,and tunable intensity amplifiers.

关键词： Talbot effect synthetic dimensions anti-PT symmetry photonic lattices

“长征精神”主题音乐作品的创作及其价值研究

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长征学刊 2024年第1期 63-75,108页

作者：汤斯惟重庆师范大学重庆400050

中国工农红军的长征创造了举世无双的奇迹,谱写了一首豪情万丈的英雄史诗,铸就了伟大的长征精神。在红军长征途中涌现出的革命歌曲,以及长征胜利以后,以长征为题材创作的音乐艺术作品,让长征精神的内涵和价值得到了充分的彰显,长征精神... 详细信息

中国工农红军的长征创造了举世无双的奇迹,谱写了一首豪情万丈的英雄史诗,铸就了伟大的长征精神。在红军长征途中涌现出的革命歌曲,以及长征胜利以后,以长征为题材创作的音乐艺术作品,让长征精神的内涵和价值得到了充分的彰显,长征精神也得到了进一步传承和弘扬。这些经典音乐作品为走好新时代的长征路提供了不竭的精神动力。

关键词：长征精神音乐作品时代价值

Bright, photostable and long-circulating NIR-Ⅱ nanoparticles for whole-process monitoring and evaluation of renal transplantation

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National Science Review 2024年第2期11卷 207-220页

作者： Rongyuan Zhang Ping Shen Yu Xiong Tianjing Wu Gang Wang Yucheng Wang Liping Zhang Han Yang Wei He Jian Du Xuedong Wei siwei Zhang Zijie Qiu Weijie Zhang Zheng Zhao Ben Zhong tang Clinical Translational Research Center of Aggregation-Induced Emission The Second Affiliated HospitalSchool of MedicineSchool of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen) Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and Engineering Shenzhen University School of Chemistry Xiangtan University HKUST-Shenzhen Research Institute Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Department of Urology The First Affiliated Hospital of Soochow University AIE Institute

Kidney transplantation is the gold standard for the treatment of end-stage renal diseases(ESRDs). However,the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transplant surgery. Improving the survival rate for renal grafts is an alternative solution to the shortage of donor kidneys. Therefore, real-time monitoring of the surgical process is crucial to the success of kidney transplantation, but efficient methods and techniques are lacking. Herein, a fluorescence technology based on bright, photostable and long-circulating aggregation-induced emission(AIE) active NIR-II nano-contrast agent DIPT-ICF nanoparticles for the whole-process monitoring and evaluation of renal transplantation has been reported. In the aggregated state, DIPT-ICF exhibits superior photophysical properties compared with the commercial dyes IR-26 and IR-1061. Besides, the long-circulating characteristic of the AIE nano-contrast agent helps to achieve renal angiography in kidney retrieval surgery,donor kidney quality evaluation, diagnosing vascular and ureteral complications, and assessment of renal graft reperfusion beyond renovascular reconstruction, which considerably outperforms the clinically approved indocyanine green(ICG).

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白细胞介素11对急性肝衰竭大鼠肝细胞凋亡及JAK/STAT信号通路的影响

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中国病原生物学杂志 2024年第3期19卷 302-307页

作者：唐小标唐芳唐满华盘箐罗四维唐萍永州职业技术学院病原生物学与医学免疫学教研室湖南永州425000

目的探究白细胞介素11对急性肝衰竭大鼠肝细胞凋亡及JAK/STAT信号通路的影响。方法将40只大鼠随机分为NC组、ALF组、IL-11组和IL-11+colivelin组。ELISA检测肝功能和炎症水平;HE染色检测肝组织病理学变化;TUNEL检测肝细胞凋亡指数;蛋白... 详细信息

目的探究白细胞介素11对急性肝衰竭大鼠肝细胞凋亡及JAK/STAT信号通路的影响。方法将40只大鼠随机分为NC组、ALF组、IL-11组和IL-11+colivelin组。ELISA检测肝功能和炎症水平;HE染色检测肝组织病理学变化;TUNEL检测肝细胞凋亡指数;蛋白质印迹法检测肝组织中JAK2、p-JAK2、STAT3、p-STAT3蛋白表达;qRT-PCR检测肝组织中JAK2、STAT3 mRNA相对表达量。结果和NC组相比,ALF组大鼠血清中ALT、AST、TBIL含量、TNF-α、IL-1β、IL-6水平、肝细胞凋亡指数、肝组织中p-JAK2/JAK2和p-STAT3/STAT3比值及JAK2、STAT3 mRNA相对表达量均明显升高(P<0.05);和ALF组相比,IL-11组大鼠血清中ALT、AST、TBIL含量、TNF-α、IL-1β、IL-6水平、肝细胞凋亡指数、肝组织中p-JAK2/JAK2和p-STAT3/STAT3比值及JAK2、STAT3 mRNA相对表达量均明显降低(P<0.05);和IL-11组相比,IL-11+colivelin组大鼠血清中ALT、AST、TBIL含量、TNF-α、IL-1β、IL-6水平、肝细胞凋亡指数、肝组织中p-JAK2/JAK2和p-STAT3/STAT3比值及JAK2、STAT3 mRNA相对表达量均明显升高(P<0.05)。结论IL-11可能通过抑制JAK2/STAT3通路激活,抑制炎症反应和肝细胞凋亡,从而改善大鼠急性肝衰竭。

关键词：白细胞介素11 急性肝衰竭肝细胞凋亡 JAK/STAT信号通路

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低功率圆柱形霍尔推进器实验特性研究

真空科学与技术学报 2024年第3期44卷 252-257页

作者：熊思维唐德礼李平川张帆陈满珍核工业西南物理研究院成都610200

随着航天技术的发展以及微小型卫星应用数量的不断增多,空间推进领域对低功率电力推进的需求越来越多。常见的环形霍尔推进器缩放至低功率时效率低下。圆柱形霍尔推进器具有较低的表面积与体积比,有利于通过磁镜效应更好地束缚电子以减... 详细信息

随着航天技术的发展以及微小型卫星应用数量的不断增多,空间推进领域对低功率电力推进的需求越来越多。常见的环形霍尔推进器缩放至低功率时效率低下。圆柱形霍尔推进器具有较低的表面积与体积比,有利于通过磁镜效应更好地束缚电子以减少通道壁处的粒子损失,从而减小通道的刻蚀和发热,这使得CHT对于低功率应用很有前景。文章进行低功率圆柱形霍尔推进器实验特性研究,在50 W功率范围内运行。实验得到了推进器在高电压、小气量、低电流工况下的工作特性、离子束特点等结果。实验表明:低功率圆柱形霍尔推进器工作电压在1000~2400 V之间,使用Ar体积流量在1.0~4.0 mL/min内,其比冲在218~1419 s,推力范围在0.118~0.78 mN,最大电流利用率为87%,最大推力效率为20.39%与先进霍尔推力器效率相当。同时发现在气体体积流量变大过程中,离子束出现强弱两种工作模式。

关键词：圆柱形霍尔推进器微型化阳极层模式转化

Growth of skyrmionic MnSi nanowires on Si： Critical importance of the SiO2 layer

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Nano Research 2014年第12期7卷 1788-1796页

作者： siwei tang Ivan Kravchenko Jieyu Yi Guixin cao Jane Howe David Mandrus Zheng Gai Department of Materials Science and Engineering University of Tennessee Knoxville TN 37996 USA Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak Ridge TN 37831 USA Hitachi High Technologies Inc. Rexdale ON M9W 6A4 Canada

在 B20 结构的 MnSi 是形成一个 skyrmion 格子的一个原型的螺旋磁体，在应用磁场下面的一块像旋涡的旋转质地。我们系统地经由控制帮助氧化物的化学蒸汽免职探索了单个水晶 MnSi nanowires 的合成并且观察了 skyrmion 的典型签名在 MnS... 详细信息

在 B20 结构的 MnSi 是形成一个 skyrmion 格子的一个原型的螺旋磁体，在应用磁场下面的一块像旋涡的旋转质地。我们系统地经由控制帮助氧化物的化学蒸汽免职探索了单个水晶 MnSi nanowires 的合成并且观察了 skyrmion 的典型签名在 MnSi nanowires 的磁性的订。SiO 的厚度 Si 底层上的 2 层在获得 B20 MnSi skyrmion nanowires 的高收益起关键作用。生长机制被建议那与最佳 SiO 的存在一致 2 厚度。一张生长阶段图为各种各样的 MnSi nanostructures 基于各种各样的生长条件的广泛的研究被构造。helicoidal 和 skyrmion 的坚持在一个维的电线中的磁性的订被交流和 dc 直接揭示磁性的大小。

关键词： SiO2层硅纳米线生长机制硅锰化学气相沉积法硅纳米结构外加磁场控制氧化