检索结果-南通市图书馆

Food Science and Human Wellness 2023年第4期12卷 1359-1368页

作者： Yangliu liu Yawei Ning Zhou Chen Panpan Han Tongxin Zhi siting li Aijin Ma Yingmin Jia School of Food and Health Beijing Technology and Business UniversityBeijing 100048China College of Food Science and Biology Hebei University of Science and TechnologyShijiazhuang 050018China

listeria monocytogenes is a worrisome food-borne pathogen threatening global food *** previous study proved that lipopeptide brevilaterin B showed efficient antibacterial activity against *** by interacting with the cell *** research further explored the antibacterial mechanism of brevilaterin B against *** at the sub-minimum inhibition concentration via transcriptomic *** B induced growth inhibition rather than direct membrane lysis in *** at the minimum inhibitory *** analysis showed 1779 difference expressed genes,including 895 up-regulated and 884 down-regulated *** Ontology and Kyoto Encyclopedia of Genes and Genomes analysis indicated that brevilaterin B influenced multiple pathways of ***,including peptidoglycan biosynthesis,membrane transport(ATP-binding cassette transports,ion transport),cellular metabolism(amino acid and lipid metabolism),ATP synthesis,and activation of the stress response(quorum sensing and bacterial chemotaxis).In conclusion,brevilaterin B affects gene expression related to biosynthesis,transport and stress response pathways on the membrane of *** present work provides the first transcriptomic assessment of the antibacterial mechanism of lipopeptide brevilaterin B at the gene level.

关键词： Antimicrobial lipopeptide Brevilaterin B Antibacterial mechanism listeria monocytogenes Transcriptomics

Progress in the preparation,identification and biological activity of walnut peptides

在线全文

学校读者我要写书评

暂无评论

Journal of Future Foods 2024年第3期4卷 205-220页

作者： Chang liu Zijie Zhang Yuting Shang siting li Junxi Xia Yiling Tian Yingmin Jia Aijin Ma School of Food and Health Beijing Technology and Business UniversityBeijing 100048China Hebei Yangyuan ZhiHui Beverage Co. Ltd.Hengshui 053000China Institution of Chinese Walnut Industry Hengshui 053000China Hebei Key Laboratory of Walnut Nutritional Function and Processing Technology Hengshui 053000China College of Food Science and Technology Hebei Agricultural UniversityBaoding 071000China

Walnuts are rich in protein and are a high-quality plant protein *** recent years,with the growth of consumer demand for functional food and food for special medical purpose,the use of walnut protein for the preparation of functional walnut peptide ingredients or additives and other compositions has received increasing ***,the improvement of the yield of walnut peptides and the clarification of their functional activities are the bottlenecks that limit the development of these *** this end,this article reviews the pretreatment,preparation,purification and identification processes of walnut peptides,as well as their biological activities such as antioxidant activity,antitumour activity,improvement of memory,antihypertension and regulation of metabolic disorders are elaborated to provide a reference for the industrial development of walnut peptides.

关键词： Walnut Peptide Extraction Isolation Purification Identification Biological activity

Integrated transcriptomics and metabolomics analysis reveal the molecular mechanism of unsaponifiable matter in delaying aging

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年

作者： Dan Hong Aijin Ma Xiao Xiao Mengge Ma Zhou Chen siting li Yingmin Jia School of Food and Health， Beijing Technology and Business University

Aging is one of the causes of cognitive dysfunction， which seriously affects people's quality of life. Unsaponifiable matter (USM) has antioxidant potential， but the molecular mechanisms that ameliorate aging and cognitive dysfunction are unknown. In this study， we used a galactose-induced brain aging mouse model and systematically analyzed the mechanism of USM in delaying aging in mice by detecting changes in serum and brain by metabolomics and *** was compared with the model group， and non-targeted metabolomics identified 68 (15 up- regulated，53down-regulated) differentially metabolites，andtranscriptomics identified 303 differentially expressed genes (228 up-regulated， 75 down-regulated). Combined multi-omics analyses showed that USM maintains normal brain function by regulating glycolytic processes， the tricarboxylic acid cycle (TCA)， tryptophan metabolism， pyrimidine metabolism， the alanine， aspartate， and glutamate metabolism， and P38MAPK pathway. Meanwhile， USM increased neurotransmitter release from GABAergic synapses and cholinergic synapses by regulating synaptic vesicle cycling. In summary， USM increased energy metabolism and enhanced brain nerve signaling in the mouse brain， thereby delaying brain aging. This investigation offers novel perspectives into the molecular mechanism of USM to mitigate brain aging.

关键词：

Unsaponifiable matter from walnut oil ameliorate memory deficits and mitochondrial dysfunction in aging mice via activating Nrf2 signaling pathway

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年

作者： Dan Hong Xiao Xiao Aijin Ma Zhou Chen siting li JunXia Xia Yiling Tian Yingmin Jia School of Food and Health， Beijing Technology and Business University Hebei Yangyuan ZhiHui Beverage Co.， Ltd. Institution of Chinese Walnut Industry Hebei Key Laboratory of Walnut Nutritional Function and Processing Technology College of Food Science and Technology， Hebei Agricultural University

Aging is an inevitable biological phenomenon that involves a multitude of physiological alterations. Dietary interventions are being considered as potential strategies for delaying age-related dysfunction. Unsaponifiable matter (USM)， a composition of highly active ingredients found in walnut oil， has demonstrated antioxidant effects. This study aims to explore the neuroprotective effects of USM on D-galactose-treated C57BL/6 mice and elucidate its underlying mechanism， which was validated in PC12 cells treated with D-galactose. The results of behavioral tests demonstrated that USM significantly improved cognitive deficits associated with aging. The morphological analysis demonstrated that USM effectively alleviated hippocampal neuronal damage， synaptic impairment， and mitochondrial dysfunction induced by D-galactose. Furthermore， USM significantly increases the antioxidant enzymes activity while reducing the malondialdehyde (MDA) andreactive oxygen species (ROS) levels. The results suggest that USM can mitigate age-related symptoms caused by D-galactose by activating the Nrf2 signaling pathway， which enhances the expression of antioxidant enzymes， restore redox balance， and improves synaptic and mitochondrial functions. This has a positive on improving cognition and memory disorders in elderly mice.

关键词：

Efficacy of chicken-derived probiotics as a treatment for colibacillosis in broilers

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Efficacy of chicken-derived probiotics as a treatment for co...

温度和催化剂添加量对催化合成SiC粉体的影响

农场动物健康舒适养殖、生物安全与疫病防控全国研讨会暨中国畜牧兽医学会动物福利与健康养殖分会第四次学术研讨会

作者： siting li Mengchu He Yingshuang Shu Xueer Gui Zhi Wang Jie Zhu Shibin Feng Yu li Xichun Wang Jinchun li Jinjie Wu College of Animal Science and Technology Anhui Agricultural University

Background:Research on the efficacy of probiotics as a treatment for colibacillosis in broilers is ***:We investigated the therapeutic role of probiotics against *** by detecting changes in intestinal microbes and aimed to discover a novel treatment against colibacillosis,as an alternative to ***:Broilers were inoculated with standard *** O157:H7 and fed compound probiotics to monitor their effects on *** days after *** challenge,serum IgG,IgM,and *** antibody were measured in the model,natural recovery,probiotic treatment,and antibiotic treatment ***:Serum IgG and IgM levels in the probiotic treatment group were significantly higher than in the control group,and significantly lower than in the model *** 3 days of treatment,serum indices were significantly higher in the probiotic treatment and antibiotic treatment groups than in the control group,but were lower than those of the natural recovery *** indices did not differ significantly between the prevention and control *** high throughput sequencing analysis,the duodenal microbial communities of the model group and natural recovery group were *** results showed that the prevalence of thick-walled bacteria decreased in the model and natural recovery groups,whereas that of the Proteus group ***,Lactobacillus count decreased and that of Enterobacter increased in the model and natural recovery ***:The addition of probiotics in feed could prevent and treat colibacillosis in broilers by maintaining the balance of intestinal flora.

关键词： probiotics Lactobacillus Bacillus Serum index Intestinal flora

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

非金属矿 2022年第6期45卷 14-16,21页

作者：李增祎陈洋李思婷刘丽湖南工学院新型建筑材料研究院湖南衡阳421002

采用Si粉、酚醛树脂和硝酸铁为原料,通过简单的催化碳化工艺在氩气下合成SiC粉体。研究了热处理温度和硝酸铁添加量对合成SiC形貌和生成量的影响,并揭示了SiC的形成机理。结果表明,热处理温度为1450℃,硝酸铁添加量为5%时,可以制备结晶... 详细信息

采用Si粉、酚醛树脂和硝酸铁为原料,通过简单的催化碳化工艺在氩气下合成SiC粉体。研究了热处理温度和硝酸铁添加量对合成SiC形貌和生成量的影响,并揭示了SiC的形成机理。结果表明,热处理温度为1450℃,硝酸铁添加量为5%时,可以制备结晶度和生成量较高的SiC粉体;不添加硝酸铁的试样中,SiC晶须以直线形和表面粗糙的絮状形貌存在;添加硝酸铁促进了SiC晶须的生成,晶须以絮状形貌为主,其直径尺寸减小,且表面变得光滑;热处理温度低于1410℃(Si熔点温度),不添加催化剂和添加催化剂的样品中晶须分别遵循气-固和气-液-固生长机制,而热处理温度高于1410℃时,晶须遵循气-液-固生长机制。

关键词： SiC晶须催化热解酚醛树脂显微结构

电子支气管镜肺泡灌洗治疗支气管扩张合并感染的效果分析

在线全文

学校读者我要写书评

暂无评论

临床医学工程 2018年第6期25卷 723-724页

作者：李思灵广东省台山市人民医院呼吸内科广东江门529200

目的探讨电子支气管镜肺泡灌洗治疗支气管扩张合并感染的效果。方法选择我院2015年2月至2017年2月收治的90例支气管扩张合并感染患者为研究对象,根据治疗方式均分为两组。对照组采用常规治疗方案,观察组给予电子支气管镜肺泡灌洗,比较... 详细信息

目的探讨电子支气管镜肺泡灌洗治疗支气管扩张合并感染的效果。方法选择我院2015年2月至2017年2月收治的90例支气管扩张合并感染患者为研究对象,根据治疗方式均分为两组。对照组采用常规治疗方案,观察组给予电子支气管镜肺泡灌洗,比较两组的临床疗效。结果观察组的治疗总有效率为95.6%,显著高于对照组的80.0%(P<0.05)。观察组的各项症状缓解时间,以及血气分析指标、炎性因子水平均显著优于对照组(P<0.05)。结论电子支气管镜肺泡灌洗治疗支气管扩张合并感染效果明显,可有效缓解临床症状,减少炎性因子水平,改善血气分析指标。

关键词：电子支气管镜肺泡灌洗支气管扩张感染

基于二苯基咪唑的氟离子荧光探针的合成及性能

在线全文

学校读者我要写书评

暂无评论

化学通报 2022年第8期85卷 999-1002,998页

作者：刘玉村周芊池李偲婷吉林师范大学化学学院四平136000

本文设计制备了一种二苯基咪唑衍生化的荧光探针,利用紫外-可见吸收光谱和荧光光谱研究探针对阴离子的选择性。在探针的乙腈溶液中引入F^(-)后,606nm处的荧光强度发生明显的猝灭,并且可通过裸眼识别F^(-)。探针对F^(-)的识别表现出高灵... 详细信息

本文设计制备了一种二苯基咪唑衍生化的荧光探针,利用紫外-可见吸收光谱和荧光光谱研究探针对阴离子的选择性。在探针的乙腈溶液中引入F^(-)后,606nm处的荧光强度发生明显的猝灭,并且可通过裸眼识别F^(-)。探针对F^(-)的识别表现出高灵敏性以及较好的抗干扰能力,检测限可低至9.43×10^(-8)mol/L。此外,制备的探针+F^(-)体系对湿度较敏感,在水分影响下该体系的颜色和荧光强度能够实现可逆恢复。

关键词：二苯基咪唑氟离子荧光探针合成性能

在线全文

学校读者我要写书评

暂无评论

酶底物法测定水中耐热大肠菌群的方法验证

广东化工 2017年第14期44卷 88-89页

作者：李斯婷刘姣广州市二次供水技术咨询服务中心检测部广东广州510010

目的验证酶底物法可用于生活饮用水、地表水、地下水中耐热大肠菌群的测定。方法通过6家实验单位对生活饮用水、地表水、地下水各30组水样分别用酶底物法和多管发酵法来做比对。结论酶底物法与多管发酵法检测数据存在相关性,且相关程度... 详细信息

目的验证酶底物法可用于生活饮用水、地表水、地下水中耐热大肠菌群的测定。方法通过6家实验单位对生活饮用水、地表水、地下水各30组水样分别用酶底物法和多管发酵法来做比对。结论酶底物法与多管发酵法检测数据存在相关性,且相关程度很高,具有一致性和稳定性。结果酶底物法可应用于生活饮用水、地表水、地下水中耐热大肠菌群的测定。

关键词：耐热大肠菌群酶底物法多管发酵法

在线全文

学校读者我要写书评

暂无评论

肉制品的加工工艺及加工中的关键控制点

农业工程技术（中国国家农产品加工信息） 2007年第3期 29-33页

作者：胡阳李思廷武汉生物工程学院生物工程系武汉430415

肉制品工业是中国食品工业的重要组成部分,随着大量先进的肉制品加工设备的出现和工艺技术的革新,肉制品工业正朝着安全和多样化的方向发展。介绍了肉制品的分类,以及几种有代表性的肉制品加工工艺,概述了肉制品加工中的关键控制点,并... 详细信息

肉制品工业是中国食品工业的重要组成部分,随着大量先进的肉制品加工设备的出现和工艺技术的革新,肉制品工业正朝着安全和多样化的方向发展。介绍了肉制品的分类,以及几种有代表性的肉制品加工工艺,概述了肉制品加工中的关键控制点,并为肉制品生产中的安全和质量控制提出了新的要求。

关键词：肉制品加工工艺关键控制点