检索结果-南通市图书馆

Prenatal bisphenol A exposure impairs the aversive and spatial memory reduces the level of NMDA receptor subunits in the hippocampus of male Sprague Dawley rats

引用

Brain Science Advances 2022年第1期8卷 57-69页

作者： Norazirah Mat Nayan Andrean Husin siti hamimah sheikh abd kadir Che Badariah abd Aziz Musalmah Mazlan Rosfaiizah Siran Centre for Neuroscience Research(NeuRon) Faculty of MedicineUniversiti Teknologi MARASungai Buloh 47000SelangorMalaysia Institute of Molecular Medicine Biotechnology(IMMB) Faculty of MedicineUniversiti Teknologi MARASungai Buloh 47000SelangorMalaysia Faculty of Dentistry Universiti Teknologi MARASungai Buloh 47000SelangorMalaysia Neuroscience Research Group(NRG) Faculty of MedicineUniversiti Teknologi MARASungai Buloh 47000SelangorMalaysia Faculty of Medicine Universiti Sains MalaysiaKubang Kerian 15200Kota Bharu KelantanMalaysia

Memory impairment in children is an ongoing issue worldwide related to a learning disability. This neurobiological condition has been suggested to associate with bisphenol A (BPA) exposure during pregnancy. BPA is an inorganic compound used to produce polycarbonate plastics and epoxy resins. We conduct this study to investigate the effects of prenatal BPA exposure on the level of the N-methyl-D-aspartate (NMDA) receptor subunits, synaptic markers of the hippocampus and neurobehavioral outcomes in rats. The pregnant rats were given a daily dose of 5 mg/kg and 50 mg/kg of BPA with 0.5% Tween 80 orally from gestation day 2 until 21 (GD21). The level of GluN2A, GluN2B, PSD-95 and synapsin I in the hippocampus and its neurobehaviour outcomes were quantified and evaluated in the male foetus and adolescent rat. Prenatal BPA exposure reduced GluN2A, GluN2B, synapsin I and PSD-95 (Postsynaptic Density-95) in the male foetus and adolescent rat hippocampus compared to the control group. The prenatal BPA exposed rats demonstrated anxiety-related behaviour and impairment in aversive and spatial memory. The findings suggested that the impairment in neurobehavioral performance may inhibit the signalling pathway in the NMDA receptor subunits in the male foetus rat hippocampus leading to learning and memory deficits when reaching adolescence.

关键词： bisphenol A memory NMDA receptor subunits neurobehavioral

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Review:Development of lanthanum strontium cobalt ferrite composite cathodes for intermediate-to low-temperature solid oxide fuel cells

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第1期14卷 11-24页

作者： Nurul Akidah BAHARUDDIN hamimah abd RAHMAN Andanastuti MUCHTAR Abu Bakar SULONG Huda abdULLAH Fuel Cell Institute Universiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia Faculty of Mechanical and Manufacturing Engineering Universiti Tun Hussein Onn Malaysia86400 BatuPahatJohorMalaysia Department of Mechanical and Materials Engineering Faculty of Engineering and Built EnvironmentUniversiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia Department of Electrical Electronic and Systems EngineeringFaculty of Engineering and Built EnvironmentUniversiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia

Solid oxide fuel cells （SOFCs） offer high energy conversion, low noise, low pollutant emission, and low processing cost. Despite many advantages, SOFCs face a major challenge in competing with other types of fuel cells because of their high operating temperature. The necessity to reduce the operational temperature of SOFCs has led to the development of research into the materials and fabrication technology of fuel cells. The use of composite cathodes significantly reduces the cathode polarization resistance and expands the triple phase boundary area available for oxygen reduction. Powder preparation and composite cathode fabrication also affect the overall performance of composite cathodes and fuel cells. Among many types of cathode materials, lanthanum-based materials such as lanthanum strontium cobalt ferrite （Lal_xSrxCOl_yFey03_~） have recently been discovered to offer great compatibility with ceria-based electrolytes in performing as composite cathode materials for intermediate- to low-temperature SOFCs （IT-LTSOFCs）. This paper reviews various ceria-based composite cathodes for IT-LTSOFCs and focuses on the aspects of progress and challenges in materials technology.

关键词： Ceria-based composite cathode Lanthanum strontium cobalt ferrite Intermediate- to low-temperature solid oxidefuel cells (IT-LTSOFCs)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spatio-temporal variation of zooplankton community structure in tropical urban waterbodies along trophic and urban gradients

引用

Ecological Processes 2019年第1期8卷 539-550页

作者： siti Balqis abd.Razak Zati Sharip Lake Research Unit Water Quality and Environment Research CentreNational Hydraulic Research Institute of MalaysiaMinistry of WaterLand and Natural ResourcesLot 5377Jalan Putra Permai43300 Seri KembanganSelangorMalaysia

The ecological impacts of urbanization and eutrophication on zooplankton communities in urban waterbodies have recently gained wide *** findings vary across species and urban *** the development of such changes affects the variation of biotic assemblages has only been explored to a limited extent in tropical urban *** and temporal variations of zooplankton community structure in 11 urban waterbodies in the Klang Valley,Malaysia were investigated along trophic and urbanization *** and water quality samples were collected three times,between May and November 2017,from two different locations in each *** three main zooplankton groups(rotifera,copepoda,and cladocera)were recorded from the study areas throughout the sampling *** zooplankton community structure,particularly with regard to rotifers and cladocerans,varied between lakes and *** diversity does not vary with lake size or distance from the city center but does vary with shoreline development index and urbanization *** zooplankton populations were dominated by rotifers,mainly Brachionus angularis at all study sites during the study period followed by copepods and *** total density of zooplankton was significantly highest(p<0.05)in the hypereutrophic lakes and during the dry *** diversity and rotifer species richness were negatively correlated with total phosphorus(TP).Diversity increased with urbanization and shoreline development,with rotifers as a potential bioindicator of trophic state in urban tropical lakes,due to their close relationship with TP.

关键词： Eutrophication Rotifer Tropical ponds Urban waterbodies Zooplankton diversity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Grid-tied PV Inverter with Sag-severity-independent Low-voltage Ride Through, Reactive Power Support, and Islanding Protection

引用

Journal of Modern Power Systems and Clean Energy 2021年第6期9卷 1300-1311页

作者： Muhammad Talha siti Rohani S.Raihan Nasrudin abd.Rahim UM Power Energy Dedicated Advanced Center(UMPEDAC) University of Malaya IEEE

This paper proposes a grid-tied photovoltaic(PV)inverter capable of low-voltage ride through(LVRT), reactive power support, and islanding protection. Unlike other LVRT inverters, the proposed inverter is independent of sag severity while maintaining the maximum power-point tracking(MPPT)under normal and faulty conditions. The addition of an energy storage buffer stage mitigates the DC-link voltage surge during sags. At the same time, the inverter injects the reactive power during back-to-back sags of variable depths. The control system of the inverter generates the appropriate reference signals for normal, LVRT, and anti-islanding modes while the MPPT continues running. The salient features of the proposed inverter are:(1) active power injection under normal grid conditions;(2)sag-depth independent LVRT with reactive power support;(3)no DC-link fluctuations;(4) continuous MPPT mode;and(5) simultaneous LVRT and anti-islanding support during a grid outage. The inverter demonstrates an uninterrupted operation and seamless transition between various operating modes. Simulations and the experimental prototype have been implemented to validate the efficacy of the proposed PV inverter.

关键词： Low-voltage ride through(LVRT) Sag maximum power point tracking(MPPT) single-phase photovoltaic(PV)inverter PV-battery system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Current Status of Riparian Vegetation along Bank of Kelantan River after the Worst Flood for Decades

引用

湿地科学 2017年第1期15卷 60-65页

作者： Onrizal siti Norasikin Ismail Muzzalifah abd Hamid Mashhor Mansor Faculty of Forestry University of Sumatera Utara Medan 2011 Indonesia School of Biological Sciences Universiti Sains Malaysia 11800 Pulau Pinang Malaysia

Undeniably Kelantan is one of the east coast states of Malaysia,which has faced yearly flooding catastrophe especially during north-east-monsoon *** aims of this study are to record the land uses from upstream to downstream of Kelantan River basin,and to record the riparian vegetation that are resistance and susceptible to flood situations in affected areas along the bank of Kelantan River after December 2014 when the worst flood was recorded for decades.A serial of surveys were conducted at 9 sampling sites(S1 to S9)from the upstream to the downstream in the *** massive clearing in the forest in the basin particularly in the upper streams was a serious *** loads of sedimentations greatly affected the hydrological system of Kelantan *** were 64 plant species were recorded in this *** sampling sites were submerged and most of the riparian plants survived although the flood levels reached 10 *** the other hand,some commercial tree species such as Elaeis guenensis,Lansium parasiticum and Nephelium lappaceum could not thrive in flooding *** should be noted that the populations of noxious,such as Mimosa pigra and Piper aduncum had colonized most parts of riparian *** due to the disturbances of catchment and riparian vegetations,the river water regimes have been ***,the ecological assessments and socio-economic approaches were recommended in order to mitigate the flood situation.

关键词：种子萌发盐分胁迫氮磷比碱蓬潮滩

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antimicrobial activity and essential oils of Curcuma aeruginosa,Curcuma mangga,and Zingiber cassumunar from Malaysia

引用

Asian Pacific Journal of Tropical Medicine 2012年第3期5卷 202-209页

作者： Tg siti Amirah Tg Kamazeri Othman abd Samah Muhammad Taher Deny Susanti Haitham Qaralleh Department of Biomedical Science Kulliyyah of ScienceInternational Islamic University MalaysiaJalan IstanaBandar Indera Mahkota25200 KuantanPahangMalaysia Kulliyyah of Pharmacy International Islamic University MalaysiaJalan IstanaBandar Indera Mahkota25200 KuantanPahangMalaysia

Objective:To analyze the chemical composition of the essential oils of Curcuma aeruginosa (***),Curcuma mangga(***),and Zingiber cassumunar(***). and study their antimicrobial ***:Essential oils obtained by steam distillation were analyzed by gas chromatography-mass speclrometry(GC-MS).The antimicrobial activity of the essential oils was evaluated against four bacteria:Bacillus cereus(***).Staphylococcus aureus(***).Escherichia coli(***).and Pseudomonas aeruginosa(***);and two fungi:Candida albicans(***) and Cyptococcus neoformans(***),using disc-diffusion and broth microdilution ***:Cycloisolongifolene,8.9-dehydro-9- formyl(35.29%) and dihydrocoslunolide(22.51%) were the major compounds in *** oil; whereas caryophyllene oxide(18.71%) and caryophyllene(12.69%) were the major compounds in *** oil:and 2,6.9,9-tetramethyl-2.6.10-cycloundecatrien-1-one(60.77%) andα-caryophyllene(23.92%) were abundant in *** *** essential oils displayed varying degrees of antimicrobial activity against all lested *** oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested,with *** being the most sensitive microorganism by having the lowest minimum inhibitory concentration(MIC) and minimum fungicidal concentration(MFC) values of 0.1μL/mL. *** oil showed mild antimicrobial activity,whereas *** had very low or weak activity against the tested ***:The preliminary results suggest promising antimicrobial properties of *** and ***,which may be useful for food preservation,pharmaceutical treatment and natural therapies.

关键词： Antimicrobial Gas chromatography-mass spectrometry Essential oil Curcuma aeruginosa Curcuma mangga Zingiber cassumunar

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Tualang honey in modulating nociceptive responses at the spinal cord in offspring of prenatally stressed rats

引用

Journal of Integrative Medicine 2019年第1期17卷 66-70页

作者： Che Badariah abd Aziz siti Qusyasyiah Ahmad Suhaimi Hidani Hasim Asma Hayati Ahmad Idris Long Rahimah Zakaria Department of Physiology School of Medical Sciences Health Campus Universiti Sains Malaysia School of Health Sciences Health Campus Universiti Sains Malaysia

Objective: This study was done to determine whether Tualang honey could prevent the altered nociceptive behaviour, with its associated changes of oxidative stress markers and morphology of the spinal cord,among the offspring of prenatally stressed ***: Pregnant rats were divided into three groups: control, stress, and stress treated with Tualang honey. The stress and stress treated with Tualang honey groups were subjected to restraint stress from day 11 of pregnancy until delivery. Ten week old male offspring(n = 9 from each group) were given formalin injection and their nociceptive behaviours were recorded. After 2 h, the rats were sacrificed, and their spinal cords were removed to assess oxidative stress activity and morphology. Nociceptive behaviour was analysed using repeated measures analysis of variance(ANOVA), while the levels of oxidative stress parameters and number of Nissl-stained neurons were analysed using a one-way ***: This study demonstrated that prenatal stress was associated with increased nociceptive behaviour, changes in the oxidative stress parameters and morphology of the spinal cord of offspring exposed to prenatal stress; administration of Tualang honey reduced the alteration of these ***: This study provides a preliminary understanding of the beneficial effects of Tualang honey against the changes in oxidative stress and neuronal damage in the spinal cord of the offspring of prenatally stressed rats.

关键词： Prenatal stress Nociceptive responses Tualang honey Spinal cord

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Sialic Acid from Edible Bird Nest on Cell Viability Associated with Brain Cognitive Performance in Mice

引用

World Journal of Traditional Chinese Medicine 2019年第4期5卷 214-219页

作者： siti Khadijah abdul Khalid Aswir abd Rashed Saleha abdul Aziz Hafandi Ahmad Departments of Veterinary Preclinical Sciences Faculty of Veterinary MedicineUniversiti Putra MalaysiaSerdangSelangor Departments of Veterinary Pathology and Microbiology Faculty of Veterinary MedicineUniversiti Putra MalaysiaSerdangSelangor Department of Nutrition Metabolic and Cardiovascular ResearchInstitute for Medical ResearchJalan PahangKuala LumpurMalaysia

Background:Edible bird nest(EBN)is a natural food product rich in glycoprotein such as sialic acid,which has been reported to improve brain *** EBN is widely consumed due to its higher nutritional contents and antioxidant status;however,an interaction of EBN on brain cell metabolic activity and viability are still ***:The objectives of this study were to identify the effect of sialic acid from EBN on the cell viability and to determine the appropriate concentration of sialic acid on cognitive performance in *** and Methods:The viability of pheochromocytoma and neuroblastoma cell lines were tested using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide *** in vivo study,7-week-old female BALB/c mice were randomly assigned into four treatment groups and were treated with sialic acid for 21 *** day 22,all mice were tested on cognitive performance by Y-maze ***:Treatment concentration of sialic acid extract and sialic acid standard at 60μg/mL(0.6 ppm)increased cell viability and showed no cytotoxicity effects in pheochromocytoma and neuroblastoma cell *** addition,an administration of higher dose of sialic acid at 0.6 ppm in animals improved Y-maze test performance,which they showed significantly higher number of entries and time spent in the novel ***:Thus,the current study shows that the sialic acid extract at 0.6 ppm improved brain cognitive performance in mice associated with an increased viability of pheochromocytoma and neuroblastoma cell lines.

关键词： Cell viability cognitive function edible bird nest mice sialic acid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pest and disease incidence of coniferous species in Taman Saujana Hijau,Putrajaya urban park,Malaysia

引用

林业研究:英文版 2023年第6期34卷 2065-2077页

作者： Nura Adila Shamsul Kamar siti Khadijah abd Rahim Annya Anak Ambrose Norida Hanim Awing Zaiton Samdin Aff endy Hassan Mohd Nazre Saleh Razak Terhem Laboratory of Forest Pathology and Tree Health Department of Forestry Science and BiodiversityFaculty of Forestry and EnvironmentUniversiti Putra Malaysia UPM43400 SerdangSelangorMalaysia Industrial Forest Research Centre Sarawak Forest Department93250 KuchingSarawakMalaysia Laboratory of Sustainable Bioresource Management(BIOREM) Institute Tropical Forestry and Forest Products(INTROP)Universiti Putra Malaysia UPM43400 SerdangSelangorMalaysia Faculty of Tropical Forestry Universiti Malaysia Sabah88400 Kota KinabaluSabahMalaysia School of Business and Economics Universiti Putra Malaysia43400 SerdangSelangorMalaysia

Taman Saujana Hijau(TSH),Putrajaya is a 41-ha urban park planted with various coniferous species from around the *** pests and disease incidences of this park are unknown and there is a need for an evaluation of the health status of this urban *** study assessed the level of pest and disease incidents of coniferous species in 12 plots of 7 species(Araucaria bidwilii,Araucaria haterophylla,Araucaria cunninghamii,Pinus caribaea,Pinus merkusii,Podocarpus polystachyus,and Podocarpus costalis).Termites,canker disease,and foliar disease are three major *** highest pest and disease incidence(PnDI)was foliar disease with a 0.49 coefficient correlation between the total number of trees and the PnDI,followed by canker disease with 0.40,and termites with *** the seven conifers,*** was the most infected followed by *** and *** was concluded that the incidence of pests and diseases in TSH was *** our knowledge,this may be the first baseline inventory of pests and diseases of coniferous species in Malaysia.

关键词： Canker disease Coniferous species Foliar disease Pest and disease incidence Urban park

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Curcumin gum Arabic nanoparticles demonstrate potent antioxidant and cytotoxic properties in human cancer cells

引用

BIOCELL 2022年第3期46卷 677-687页

作者： abdELKADER HASSANI siti ASLINA HUSSAIN MOTHANNA SADIQ AL-QUBAISI MOHAMED LAKHDER BELFAR HAKIM BELKHALFA HAMID HAMMAD ENEZEI HAMID ZENTOU WISAM NABEEL IBRAHIM abd ALMONEM DOOLAANEA Department of Pharmaceutical Technology Faculty of PharmacyInternational Islamic University MalaysiaKuantanMalaysia Department of Chemical and Environmental Engineering University Putra MalaysiaSerdang43400Malaysia Department of Chemistry Faculty of Mathematics and Material SciencesUniversity of kasdi MurbahOuarglaAlgeria UPM-MAKNA Cancer Research Laboratory Institute of BioscienceUniversity Putra MalaysiaSerdangMalaysia Scientific and Technical Research Center in Physicochemical Analysis Bou-IsmailTipazaAlgeria Department of Oral&Maxillofacial Surgery College of DentistryUniversity of AnbarRamadiIraq Department of Biomedical Sciences College of Health SciencesQU HealthQatar UniversityDohaQatar Pharmaceutical Research Unit QU HealthQatar UniversityDohaQatar

The main purpose of the study was to enhance the stability and therapeutic effects of Curcumin(Cur)through nanoformulation with gum Arabic(GA)as a coating agent through an efficient synthetic *** antioxidant properties of the developed nanoparticles(Cur/GANPs)were assessed through several in vitro assays,such asβ-carotene bleaching activity,DPPH,and nitric oxide scavenging activities in addition to evaluating its inhibitory activity on angiotensinconverting enzyme(ACE).The cytotoxicity of Cur/GANPs was evaluated in vitro using different types of human cancer cells including breast cancer(MCF7,MDA-MB231),liver cancer(HepG2),and colon cancer(HT29)*** prepared particles displayed an elliptical shape with a size ranging between 20–260 nm and a potential difference of–15 *** Cur/GANPs exhibited significant antioxidant activity compared to free curcumin when using concentrations between 31.5 and 500μg/*** Cur/GANPs also had inhibited the growth of all cancer cell lines in a proportional trend with concentrations ***,the encapsulation with gum Arabic has augmented the antioxidant and anti-neoplastic effects of ***,Cur/GANPs may have effective therapeutic properties in diseases attributed to oxidative stress like cancer and hypertension.

关键词： Curcumin Gum arabic Nanoparticles Cancer cells Antioxidants

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：