检索结果-南通市图书馆

Does carrier fluid reduce low flow drug infusion error from syringe size?

World Journal of Clinical Pediatrics 2020年第2期9卷 17-28页

作者： Zachary C Madson sitaram vangala Grace T Sund James A Lin Pediatric Hospitalist Medicine Lutheran Children's HospitalFort WayneIN 46804United States Medicine Statistics Core David Geffen School of Medicine at UCLALos AngelesCA 90095United States Department of Nursing UCLA Mattel Children's HospitalLos AngelesCA 90095United States Department of Pediatrics David Geffen School of Medicine at UCLALos AngelesCA 90095United States

BACKGROUND Critically ill neonates and pediatric patients commonly require multiple low flow *** limitations are imposed by small body habitus and comorbidities like cardiopulmonary disease,renal failure,or fluid *** access is limited by diminutive *** fluids or parenteral nutrition in conjunction with actively titrated infusions such as insulin,fentanyl,prostaglandins,inotropes and vasopressors may necessitate simultaneous infusions using a single lumen to maintain vascular catheter *** requirement for multiple titratable infusions requires concentrated medications at low flows,rather than more dilute drugs at higher flows that in combination may volume overload small *** To determine whether carrier fluid reduces variability that variability of low flow drug infusions is proportional to syringe size in pediatric critical *** We assessed concentrations of orange“drug”in a 0.2 mL/h low flow clinical model with blue dyed carrier fluid at 5 mL/h,using 3-,10-,or 60-mL syringes.A graduated volumetric pipette was used to measure total *** time to target concentration was 30,21,and 46 min in 3-,10-,and 60-mL syringes,respectively(P=0.42).After achieving target concentration,more dilute drug was delivered by 60-mL(P<0.001)and 10-mL syringes(P=0.04)compared to 3-mL *** overdoses were observed during the initial 45 min of infusion in 10-and 60-mL *** volumes infused after target concentration were less in the 60-mL condition compared to 3-mL(P<0.01)and 10-mL(P<0.001)*** Linear mixed effects models demonstrated lesser delivered drug concentrations in the initial 30 min by 3-mL compared to 10-and 60-mL syringes(P=0.005 and P<0.001,respectively)but greater drug concentrations and total infused drug in the subsequent 30-60 and 60-90 min intervals with the 3-and 10-mL compared to 60-mL *** With carrier fluid,larger syringes were associated with significantly

关键词： Infusion pumps Intensive care Neonatal Nursing research Patient safety Spectrophotometry Syringes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：