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Corrosion and tribocorrosion resistance of MAO-based composite coating on AZ31 magnesium alloy

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Journal of Magnesium and Alloys 2022年第12期10卷 3406-3417页

作者： siqin Liu Guihua Li Yuming Qi Zhenjun Peng Yinping Ye Jun Liang State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000PR China Key Laboratory of Science and Technology on Wear and Protection of Materials Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000PR China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049PR China

In this paper, a multi-functional composite coating with low friction coefficient, high wear resistance and excellent tribocorrosion resistance is fabricated on AZ31 Mg alloys by micro-arc oxidation and spray-coating methods. The microstructure, and composition of the coating are characterized by SEM, EDS, XRD, and FT-IR. Potentiodynamic polarization and EIS tests are conducted to evaluate the corrosion resistance of the composite coating. The tribocorrosion property is also studied using pin-on-disk tribometer in 3.5 wt.% Na Cl solution. It is found that the composite coating possesses better long-term corrosion resistance than the single MAO coating. The tribocorrosion tests prove that the composite coating exhibits much better wear and tribocorrosion resistance than the single MAO coating and can protect the substrate from corrosion under a sliding condition.

关键词： Magnesium alloy Micro-arc oxidation Composite coating Corrosion Tribocorrosion

俞氏化瘀止血方联合左炔诺孕酮宫内缓释系统治疗子宫腺肌病的前瞻性、随机、双盲、安慰剂对照研究

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海军军医大学学报 2024年第9期45卷 1069-1076页

作者：李彧程雯李森蒋继兰杨思勤孙峰齐英俞超芹许泓上海交通大学医学院附属国际和平妇幼保健院妇科上海200030 上海市胚胎源性疾病重点实验室上海200030 海军军医大学(第二军医大学)第一附属医院中医妇科上海200433

目的探究俞氏化瘀止血方联合左炔诺孕酮宫内缓释系统(LNG-IUS)治疗子宫腺肌病(AM)的疗效及安全性。方法采用前瞻性、随机、双盲、安慰剂对照研究设计,选取2019年12月至2022年12月就诊于上海交通大学医学院附属国际和平妇幼保健院及海军... 详细信息

目的探究俞氏化瘀止血方联合左炔诺孕酮宫内缓释系统(LNG-IUS)治疗子宫腺肌病(AM)的疗效及安全性。方法采用前瞻性、随机、双盲、安慰剂对照研究设计,选取2019年12月至2022年12月就诊于上海交通大学医学院附属国际和平妇幼保健院及海军军医大学(第二军医大学)第一附属医院门诊的AM患者102例,随机分为化瘀方组和安慰剂组进行双盲临床试验,化瘀方组放置LNG-IUS后1个月加用俞氏化瘀止血方治疗,安慰剂组放置LNG-IUS后1个月加用安慰剂治疗,俞氏化瘀止血方和安慰剂均服用3个月。共95例完成随访,其中化瘀方组47例、安慰剂组48例;脱落7例,脱落率为6.86%。比较两组患者的月经失血图(PBAC)评分、子宫点滴出血天数、痛经视觉模拟量表(VAS)评分、子宫体积、血清糖类抗原125(CA125)水平和中医证候量化评分,并进行安全性评价。结果服药3个月后,与安慰剂组相比,化瘀方组患者PBAC评分、点滴出血天数、子宫体积、血清CA125水平、中医证候量化评分均降低(均P0.05)。随访过程中,化瘀方组患者均未接受手术治疗,安慰剂组有2例行手术治疗(其中1例行腹腔镜子宫全切术,1例行腹腔镜子宫腺肌瘤切除术),两组手术率差异无统计学意义(P>0.05)。安慰剂组与化瘀方组均未见明显不良反应。结论俞氏化瘀止血方可明显改善AM患者的点滴出血情况,促进子宫体积缩小,降低血清CA125水平,改善AM中医证候。建议AM患者在放置LNG-IUS后常规服用俞氏化瘀止血方制剂,以减少LNG-IUS的不良反应。

关键词：子宫腺肌病左炔诺孕酮宫内缓释系统俞氏化瘀止血方随机对照试验

Studies on the Inversion Phenomenon of Physical Properties Observed in the Huagang Formation Reservoir in the Xihu Sag Based on the Water-Rock Reaction Experiments

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Journal of Ocean University of China 2021年第4期20卷 755-764页

作者： HUANG siqin XU Fanghao XU Guosheng CUI Hengyuan ZHANG Wu State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu 610059China CNOOC(China)Co. Ltd.Shanghai CompanyShanghai 200030China

In the Xihu Sag,the reservoirs of the Paleogene Huagang formation have entered the middle diagenetic stage A and the rock physical properties of the water layer are considerably more suitable for the gas migration and storage than those of the present gas layer,indicating the inversion of the physical *** this study,core samples were collected from the corresponding reservoir to conduct water-rock reaction experiments in acidic,alkaline,and neutral systems under the specific temperature and *** reasons for the inversion of physical properties were investigated based on the experiment results in reservoir diagenetic *** inversion of physical properties can be attributed to the fact that the diagenetic environment around the gas-water interface controls the water-rock reaction *** different types of acidic substances,two different situations corresponding to inverted physical properties were analyzed along with the corresponding *** the pore fluid is acidic,the physical properties make the overall water layer a better reservoir space than the gas layer,which can be referred to as the overall inversion of physical *** the fluid were generally neutral or weakly alkaline and the gas layer was rich in CO2,only the physical properties of the water layer adjacent to the gas-water interface were more favorable for the gas migration than those of the gas *** phenomenon can be referred to as the near-interface inversion of physical properties.

关键词： Xihu Sag water-rock reaction reservoir evolution inverted physical properties diagenetic environment special phe-nomenon

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晋北食俗中的糕文化及其文化功能研究

呼伦贝尔学院学报 2024年第4期32卷 42-47页

作者：岳丽白霞斯琴小长谷有纪北方民族大学宁夏银川750021 日本国立民族学博物馆日本大阪5658511

饮食文化研究是开展社会整体文化研究的重要切入口。糕是晋北的传统食物,但并非仅作果腹之用。在当地生态和历史环境的共同形塑下,逐渐生成了一种以糕为核心的食文化。通过对晋北糕的做法、吃法和应用场合等一系列文化事项进行深描,从... 详细信息

饮食文化研究是开展社会整体文化研究的重要切入口。糕是晋北的传统食物,但并非仅作果腹之用。在当地生态和历史环境的共同形塑下,逐渐生成了一种以糕为核心的食文化。通过对晋北糕的做法、吃法和应用场合等一系列文化事项进行深描,从文化功能论的角度阐释糕在晋北社会中所发挥的礼的教化、规范行为、强化认同、促进交往等社会文化功能,挖掘传统饮食文化价值的同时,从中管窥地方社会文化内核,有助于深化人们对传统饮食生成的文化土壤和社会基质的认识,并丰富国内饮食人类学的个案研究。

关键词：晋北地区糕文化文化功能

一类不连续不定Sturm-Liouville算子的自共轭性

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内蒙古大学学报(自然科学版) 2024年第4期55卷 337-344页

作者：甄国华姚斯琴李润梅内蒙古大学数学科学学院

该文研究了一类首项系数与权函数均多次变号且带有转移条件的Sturm-Liouville算子的自共轭性。建立新的完备不定度规空间K,将所研究的Sturm-Liouville问题转化为对新算子A的研究，证明了算子A的自共轭性。

关键词：不定Sturm-Liouville算子边界条件转移条件自共轭性

Biomaterial-induced macrophage polarization for bone regeneration

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Chinese Chemical Letters 2023年第6期34卷 164-171页

作者： Long Chen Zhicheng Yao siqin Zhang Kuihan Tang Qiming Yang Yuanzheng wang Bohan Li Yingjie Nie Xiaobin Tian Li Sun Department of Orthopedics Guizhou Provincial People’s HospitalGuiyang 550000China Medical College Guizhou UniversityGuiyang 550000China Department of Materials Science and Engineering Translational Tissue Engineering CenterJohns Hopkins UniversityBaltimoreMD 21218United States Department of Endocrinology and Metabolism Guizhou Provincial People’s HospitalGuiyang 550000China The Central Laboratory Guizhou Provincial People’s HospitalGuiyang 550000China Department of Orthopedics The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550000China

As the main target cells of immune regulation,macrophages play an important role in the bone regeneration *** can be polarized into the M1 and M2 types under the stimulation of different *** have proinflammatory and anti-inflammatory effects,respectively,and play key roles in different stages of bone *** ratio of M1 to M2 macrophages can be regulated by immunomodulatory biomaterials to promote bone repair and *** this paper,we review the recent literature on the chemical,physical and biological properties of biomaterials and the regulation of macrophage polarization under the influence of other *** also cover new methods for preparing immunomodulatory biomaterials for bone *** paper will provide new design ideas for the development of biomaterials with immunological properties and will support the clinical translation of bone-related medical biomaterials.

关键词： Macrophage polarization Biomaterial Nano materials Bone regeneration Immune response

Surgical outcomes of hand-assisted laparoscopic liver resection vs. open liver resection: A retrospective propensity scorematched cohort study

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Chinese Journal of Cancer Research 2019年第5期31卷 818-824页

作者： Shengtao Lin Fan Wu Liming wang Yunhe Liu Yiling Zheng Tana siqin Weiqi Rong Jianxiong Wu Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Objective: Hand-assisted laparoscopic liver resection has the advantages of open and laparoscopic *** is still lack of comparison of surgical outcomes between hand-assistied laparoscopic liver resection(HALLR)and open liver resection(OLR). This study compared the surgical outcomes of the two approaches between wellmatched patient ***: Patients who received liver resection during January 2014 and October 2017 in Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College were included in this retrospective study. Propensity score matching(PSM) was performed to reduce selection bias between the two groups. Operation and short-term surgical outcomes were compared between the well matched ***: During this period, 232 patients with a median age of 55.1 years old received OLR, while 49 patients with a median age of 54.7 years old received HALLR. Compared with HALLR group, OLR group has a higher proportion in male patients(190/232, 81.9% vs. 34/49, 69.4%, P=0.048) and lower albumin(43.2±4.5 vs. 44.8±3.7,P=0.020). After PSM, 49 patients from each group were included in the following analysis. Two groups were well balanced in their baseline characteristics, liver functions, preoperative treatments, abdominal surgery history, and surgical difficulty. None perioperative mortality was observed in both groups. Operation time and postoperative complications were similar in two groups(P=0.935, P=0.056). The HALLR group showed less bleeding amount(177.8±217.1 mL vs. 283.1±225.0 mL, P=0.003) and shorter postoperative stay period(6.9±2.2 d vs. 9.0±3.5 d,P=0.001).Conclusions: We demonstrated that hand-assisted laparoscopic surgery is feasible and safe for liver resection,including some difficult cases. HALLR can provide better bleeding control and faster recovery after surgery.

关键词： Surgical outcomes hand-assisted laparoscopic surgery liver resection

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结直肠癌患者性健康管理的最佳证据总结

中华现代护理杂志 2024年第21期30卷 2837-2843页

作者：范婧慧张丽丽晏思琴方承媛王高华武汉大学人民医院护理部武汉430060 武汉大学人民医院精神卫生中心武汉430060

目的整合国内外结直肠癌患者性健康管理的最佳证据,为临床实践提供指引。方法系统检索国内外数据库及网站中关于结直肠癌患者性健康管理的证据,并对符合质量评价标准的文献进行证据提取和总结。检索时限为2003年7月—2023年7月。结果最... 详细信息

目的整合国内外结直肠癌患者性健康管理的最佳证据,为临床实践提供指引。方法系统检索国内外数据库及网站中关于结直肠癌患者性健康管理的证据,并对符合质量评价标准的文献进行证据提取和总结。检索时限为2003年7月—2023年7月。结果最终纳入文献16篇,其中临床决策支持5篇、临床实践指南6篇、专家共识/团体标准3篇、系统评价2篇。最终形成34条推荐意见,包括评估与筛查、常用评估工具、性功能障碍的表现、性问题的应对策略、心理干预、生育力保护的措施、健康教育、随访管理8个方面。结论本研究总结了结直肠癌患者性健康管理的最佳证据,需结合医护人员对患者病情的评估及临床实际情境进行选择性运用,以保证患者性健康管理策略的有效性和科学性,促进最佳证据向临床实践的转化。

关键词：结直肠癌性健康性功能障碍管理证据总结

补肾健脾通络方治疗老年衰弱综合征临床疗效观察

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中华中医药学刊 2024年第2期42卷 228-231页

作者：姜凤依史晓季思勤施丹鲍晓敏周永明上海中医药大学上海201203 上海中医药大学附属岳阳中西医结合医院上海200437

目的观察补肾健脾通络方治疗老年衰弱综合征临床疗效及安全性。方法研究纳入2021年1月—2022年6月收治的老年衰弱综合征患者共计102例,以随机数字表法将患者分为对照组与观察组,每组51例,对照组患者采取临床常规治疗,观察组患者采取常... 详细信息

目的观察补肾健脾通络方治疗老年衰弱综合征临床疗效及安全性。方法研究纳入2021年1月—2022年6月收治的老年衰弱综合征患者共计102例,以随机数字表法将患者分为对照组与观察组,每组51例,对照组患者采取临床常规治疗,观察组患者采取常规治疗结合补肾健脾通络方治疗。观察各组数据:治疗总有效率、治疗前后患者中医证候总积分变化及Fried表型衰弱量表(frailty phenotype,FP)评分变化及白介素-6(interleukin 6,IL-6)、超敏C反应蛋白(C-ReactiveProtein,hs-CRP)水平变化、握力变化及起立-行走计时测试(Timed Up and Go test,TUG)变化、5次坐立试验(five-times-sit-to-stand test,FTSST)变化、步速变化、体质指数(Body Mass Index,BMI)变化及四肢骨骼肌质量指数(appendicular skeletal muscle mass index,ASMI)变化、简易精神状态评分(Mini-mental State Examination,MMSE)变化、匹兹堡睡眠指数(Pittsburgh sleep quality index,PSQI)评分变化、日常生活能力(Activity of Daily Living,ADL)评分变化、微型营养评估(mini nutritionaal assessment,MNA)评分变化、患者治疗满意度、不良反应。结果观察组患者治疗总有效率比对照组高[96.08%(49/51)vs84.31%(43/51)],P0.05,治疗后各组患者中医证候总积分、FP评分、IL-6、hs-CRP水平、握力、TUG测试结果及FTSST测试结果、步速、BMI、ASMI、MMSE评分、PSQI评分、ADL评分、MNA评分均改善,观察组患者治疗后中医证候总积分、FP评分、IL-6、hs-CRP水平、握力、TUG测试结果及FTSST测试结果、步速、BMI、ASMI、MMSE评分、PSQI评分、ADL评分、MNA评分均优于对照组患者,P0.05。结论补肾健脾通络方治疗老年衰弱综合征临床疗效显著,能缓解衰弱综合征患者的临床症状,抑制患者机体炎性反应,增加肌肉质量,改善睡眠,提高生活质量,且无不良反应,较为安全可靠,值得应用。

关键词：老年衰弱综合征补肾健脾通络方临床疗效生活质量中医证候积分

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