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World Journal of Diabetes 2024年第2期15卷 133-136页

作者： Mahmoud Nassar ajay Chaudhuri Husam Ghanim Paresh Dandona Department of Internal Medicine Division of EndocrinologyDiabetes and MetabolismJacobs School of Medicine and Biomedical SciencesUniversity of BuffaloBuffaloNY 14221United States

Type 1 diabetes(T1D)is a chronic autoimmune condition that destroys insulinproducing beta cells in the pancreas,leading to insulin deficiency and *** management of T1D primarily focuses on exogenous insulin replacement to control blood glucose ***,this approach does not address the underlying autoimmune process or prevent the progressive loss of beta *** research has explored the potential of glucagon-like peptide-1 receptor agonists(GLP-1RAs)as a novel intervention to modify the disease course and delay the onset of ***-1RAs are medications initially developed for treating type 2 *** exert their effects by enhancing glucose-dependent insulin secretion,suppressing glucagon secretion,and slowing gastric *** evidence suggests that GLP-1RAs may also benefit the treatment of newly diagnosed patients with *** article aims to highlight the potential of GLP-1RAs as an intervention to delay the onset of T1D,possibly through their potential immunomodulatory and anti-inflammatory effects and preservation of *** article aims to explore the potential of shifting the paradigm of T1D management from reactive insulin replacement to proactive disease modification,which should open new avenues for preventing and treating T1D,improving the quality of life and long-term outcomes for individuals at risk of T1D.

关键词： Type 1 diabetes Semaglutide Glucagon-like peptide-1 receptor agonists Insulin therapy Autoimmune response Blood glucose monitoring Β-cell preservation Early screening Teplizumab Randomized controlled trials

Pumpkin seeds as nutraceutical and functional food ingredient for future:A review

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Grain & Oil Science and Technology 2024年第1期7卷 12-29页

作者： Arunima singh Vivek Kumar Department of Food Technology Harcourt Butler Technical UniversityKanpur 208002UPIndia

Pumpkin belongs to the family of Cucurbitaceae,which comprises several species that has economical as well as agronomical *** parts of pumpkin are edible and laden with beneficial neutraceutical *** seeds are valuable source protein which can help in eradicating protein malnutrition and lipids(rich in PUFAs)contains essential as well as non essential fatty acids which prevents from various ailments like cancer and other cardiovascular ***,seeds of pumpkin are abundant in macro(magnesium,phosphorous,potassium,sodium and calcium)and micro minerals(iron,copper,manganese,zinc and selenium),they can be used as an incredible dietary supplement which in turn helps in curbing various deficiency *** review enlightens the characteristics of pumpkin seeds,process of valorization of pumpkin seeds and the effect of processing on their nutritional composition which have been studied currently with the aim to use this wonder seeds for human *** seeds possess many bioactive compounds like polyphenols,flavonoids,phytosterols and squalene which makes it a lucrative raw material for pharmacological and food *** seeds work as anti-depressant and helps majorly in the treatment of benign prostate hyperplasia(BHP).Daily consumption of pumpkin seeds can reduce the chances of Alzheimer's and Parkinson's *** seeds are rich in tocopherols and can be used for oil extraction for edible purposes and utilized in other food formulations for future use.

关键词： Pumpkin seed Neutraceutical properties Nutritional composition Tocopherols Squalene β-Carotene Waste valorization

Layered Potassium Titanium Niobate/Reduced Graphene Oxide Nanocomposite as a Potassium‑Ion Battery Anode

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Nano-Micro Letters 2024年第1期16卷 1-16页

作者： Charlie A.F.Nason ajay Piriya Vijaya Kumar Saroja Yi Lu Runzhe Wei Yupei Han Yang Xu Department of Chemistry University College London20 Gordon StreetLondon WC1H 0AJUK

With graphite currently leading as the most viable anode for potassium-ion batteries(KIBs),other materials have been left relatively *** metal oxides are among these,with many positive attributes such as synthetic maturity,longterm cycling stability and fast redox ***,to address this research deficiency we report herein a layered potassium titanium niobate KTiNbO5(KTNO)and its rGO nanocomposite(KTNO/rGO)synthesised via solvothermal methods as a high-performance anode for *** effective distribution across the electrically conductive rGO,the electrochemical performance of the KTNO nanoparticles was *** potassium storage performance of the KTNO/rGO was demonstrated by its first charge capacity of 128.1 mAh g^(−1) and reversible capacity of 97.5 mAh g^(−1) after 500 cycles at 20 mA g^(−1),retaining 76.1%of the initial capacity,with an exceptional rate performance of 54.2 mAh g^(−1)at 1 A g^(−1).Furthermore,to investigate the attributes of KTNO in-situ XRD was performed,indicating a low-strain ***-situ X-ray photoelectron spectra further investigated the mechanism of charge storage,with the titanium showing greater redox reversibility than the *** work suggests this lowstrain nature is a highly advantageous property and well worth regarding KTNO as a promising anode for future high-performance KIBs.

关键词： Potassium-ion batteries Intercalation Transition metal oxides Anodes Nanocomposite

A comprehensive review on pharmacognosy, phytochemistry and pharmacological activities of 8 potent Prunus species of southeast Asia

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Journal of Traditional Chinese Medicine 2024年第3期44卷 620-628页

作者： Shikha Agrawal Adarsh Kumar Ankit Kumar singh Harshwardhan singh Suresh Thareja Pradeep Kumar Department of Pharmaceutical Sciences and Natural Products Central University of PunjabBathinda 151401India

Genus Prunus comprising around 430 species is a vast important genus of family Rosaceae, subfamily amygdalaoidae. Among all 430 species, around 19 important species are commonly found in Indian subcontinent due to their broad nutritional and economic importance. Some most common species of genus Prunus are Prunus amygdalus, Prunus persica, Prunus armeniaca, Prunus avium, Prunus cerasus, Prunus cerasoides, Prunus domestica, Prunus mahaleb, etc. A newly introduced species of Prunus i.e Prunus sunhangii is recently discovered which is morphologically very similar to Prunus cerasoides. Plants of Prunus species are short to medium-sized deciduous trees mainly found in the northern hemisphere. In India and its subcontinent,it extends from the Himalayas to Sikkim, Meghalaya,Bhutan, Myanmar etc. Different Prunus species have been extensively studied for their morphological,microscopic, pharmacological and phytoconstituents characteristics. Total phenolic content of Prunus species explains the presence of phenols in high quantity and pharmacological activity due to phenols. Phytochemical screening of species of genus Prunus shows the presence of wide phytoconstituents which contributes in their pharmacological significance and reveals the therapeutic potential and traditional medicinal significance of this genus. Genus Prunus showed a potent antioxidant activity analyzed by 1,1-diphenyl-2-picryl-hydrazyl radical assay. Plant species belonging to the genus Prunus is widely used traditionally for the treatment of various disorders. Some specific Prunus species possess potent anticancer, anti-inflammatory,hypoglycemic etc. activity which makes the genus more interesting for further research and findings. This review is an attempt to summarize the comprehensive study of Prunus species from its distribution, morphological characters to phytoconstituents, and pharmacological activity.

关键词： Rosaceae Prunus antineoplastic agents hypoglycemic agents distribution phytochemistry review

Tuning the crystallinity of titanium nitride on copper-embedded carbon nanofiber interlayers for accelerated electrochemical kinetics in lithium-sulfur batteries

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Carbon Energy 2024年第6期6卷 40-55页

作者： Yinyu Xiang Liqiang Lu Feng Yan Debarun Sengupta Petra Rudolf ajay Giri Prakash Kottapalli Yutao Pei Advanced Production Engineering Engineering and Technology Institute GroningenUniversity of GroningenGroningenThe Netherlands Zernike Institute for Advanced Materials University of GroningenGroningenThe Netherlands

The development of lithium-sulfur(Li-S)batteries is hindered by the disadvantages of shuttling of polysulfides and the sluggish redox kinetics of the conversion of sulfur species during discharge and ***,the crystallinities of a titanium nitride(TiN)film on copper-embedded carbon nanofibers(Cu-CNFs)are regulated and the nanofibers are used as interlayers to resolve the aforementioned crucial issues.A low-crystalline TiN-coated Cu-CNF(L-TiN-Cu-CNF)interlayer is compared with its highly crystalline counterpart(H-TiN-Cu-CNFs).It is demonstrated that the L-TiN coating not only strengthens the chemical adsorption toward polysulfides but also greatly accelerates the electrochemical conversion of *** to robust carbon frameworks and enhanced kinetics,impressive highrate performance at 2 C(913 mAh g^(-1)based on sulfur)as well as remarkable cyclic stability up to 300 cycles(626 mAh g^(-1))with capacity retention of 46.5%is realized for L-TiN-Cu-CNF interlayer-configured Li-S *** under high loading(3.8 mg cm^(-2))of sulfur and relatively lean electrolyte(10μL electrolyte per milligram sulfur)conditions,the Li-S battery equipped with L-TiN-Cu-CNF interlayers delivers a high capacity of 1144 mAh g^(-1)with cathodic capacity of 4.25 mAh cm^(-2)at 0.1 C,providing a potential pathway toward the design of multifunctional interlayers for highly efficient Li-S batteries.

关键词： crystallinity electrochemical kinetics interlayer lithium-sulfur batteries titanium nitride

Use of waste plastic oil as a fuel in reactivity-controlled compression ignition engines: a bibliometric investigation from 2017-23

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CLEAN ENERGY 2024年第3期8卷 206-222页

作者： Kanchan, Sumit Sandhu, Sarbjot singh Dr BR Ambedkar Natl Inst Technol Dept Mech Engn Jalandhar Punjab India Lovely Profess Univ Sch Mech Engn Jalandhar Punjab India

Waste plastic oil, generated through the pyrolysis of plastic without oxygen, known as plastic-to-fuel conversion, stands as a promising alternative fuel. This research employs bibliometric analysis, a quantitative method, to comprehensively assess publications in the domain of waste plastic oil integration within reactivity-controlled compression ignition engines. Utilizing Scopus as the primary repository post-2017, the study categorizes information into pivotal aspects, including influential journals, countries, authors, affiliations, document types, thematic areas, sponsors and keywords. The analysis reveals significant contributions from diverse nations, prominently India, China, Turkey and Malaysia. Noteworthy is the prevalence of Energy, Engineering and Chemical Engineering as thematic focal points, with the journal Fuel leading the count followed by the journal Energy emerging as a prominent conduit. Institutional contributions are prolific, led by Gandhi Institute of Technology and Management University and Vellore Institute of Technology. Renowned authors 'Gugulothu S.K' and 'He Z' play a pivotal role in shaping the discourse. The National Natural Science Foundation of China stands out as a primary patron. This bibliometric analysis provides a structured understanding of waste plastic oil integration in reactivity-controlled compression ignition engines, laying the groundwork for future research avenues. The study identifies potential research platforms beyond Scopus, including Web of Science, CrossRef, Science Direct and Google Scholar, as valuable repositories for further exploration. Moreover, after careful observation of the research articles published by the top 10 authors as found in the study, it was found that the authors share a few common characteristics that helped them in advancing the understanding and application of waste plastic oil in reactivity-controlled compression ignition engines. These are also summarized in the present study with sup

关键词： bibliometric analysis plastic-to-fuel waste plastic oil RCCI engine Scopus database DIESEL-ENGINE CATALYTIC PYROLYSIS EMISSION CHARACTERISTICS COMBUSTION CHARACTERISTICS INJECTION PARAMETERS PERFORMANCE BLENDS IMPACT BIODIESEL PRODUCTS

Nanotechnology approaches towards biodeterioration-resistant wood:A review

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Journal of Bioresources and Bioproducts 2024年第1期9卷 3-26页

作者： Ayyoob Arpanaei Qiliang Fu Tripti singh Scion Private Bag 3020Rotorua 3046New Zealand Co-Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037China

Wood can be a suitable alternative to energy-intensive materials in various ***-ertheless,its susceptibility to weathering and decay has significantly hindered the broad adop-tion of the most commercially significant wood *** current solutions do tackle certain challenges,they often come with disadvantages like high costs,environmental risks,and/or ***-based methods can be employed to mitigate these weaknesses and create durable,sustainable wood *** this review,we delve into cutting-edge advance-ments in the development of biodeterioration-resistant wood through innovative nanotechnol-ogy *** methods usually involve the application of nanomaterials,either pos-sessing biocidal properties or serving as carriers for *** systematically describe these approaches and compare them to conventional wood modification ***,this re-view provides a brief overview of the prevalent biodeteriorating organisms and their mechanisms of action,which notably impact the development and choice of a suitable strategy for wood mod-ification/*** the requirements of biodeteriorating organisms for growth and wood degradation,it is expected that the new nanotechnology-based approaches to enhance wood dura-bility may provide innovative broad-spectrum biocidal *** systems can simulta-neously induce alterations in the physicochemical properties of wood,thereby constraining the availability of the growth *** alterations can efficiently inhibit the biodeterio-ration process by decreasing water absorption,restricting access to the wood components,and reducing void spaces within the wood ***,this review highlights the new oppor-tunities,challenges,and perspectives of nanotechnology methods for biodeterioration-resistant wood,through which some techno-economic,environmental and safety aspects associated with these methods are addressed.

关键词： Wood durability Decay Wood modification Biodeterioration mechanisms Biocides Wood nanotechnology

Non-static plane symmetric perfect fluid solutions and Killing symmetries in f(R,T)gravity

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Communications in Theoretical Physics 2024年第2期76卷 145-150页

作者： Preeti Dalal Karanjeet singh Sachin Kumar Department of Mathematics and Statistics Central University of PunjabBathinda151401PunjabIndia Department of Mathematics Jaypee University of Information TechnologySolan173234Himachal PradeshIndia

In this paper,the non-static solutions for perfect fluid distribution with plane symmetry in f(R,T)gravitational theory are ***,using the Lie symmetries,symmetry reductions are performed for considered vector fields to reduce the number of independent ***,corresponding to each reduction,exact solutions are *** vectors lead to different conserved ***,we figure out the Killing vector fields corresponding to all derived *** derived solutions are further studied and it is observed that all of the obtained spacetimes,at least admit to the minimal symmetry group which consists of δ_(y),δ_(z) and -zδ_(y)+yδ_(z).The obtained metrics,admit to 3,4,6,and 10,Killing vector *** of linear momentum in the direction of y and z,and angular momentum along the x axis is provided by all derived solutions.

关键词： Einstein field equations perfect fluid solutions f(R T)gravity killing symmetries

A Novel Multi-objective Protection Coordination Scheme for a Microgrid with Optimal Deployment of Dual-setting ROCOV Based Relays

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Protection and Control of Modern Power Systems 2024年第4期9卷 23-38页

作者： Praveen Kumar Gupta Priyanshul Niranjan Niraj Kumar Choudhary Nitin singh Ravindra Kumar singh the Department of Electrical Engineering Motilal Nehru National Institute of Technology AllahabadPrayagraj 211004India

Relay coordination is crucial in electrical power systems to protect against malfunctions and damage caused by unexpected events like short *** address the challenge associated with the reverse direction of fault current,dual-setting(DS)directional over-current relays have evolved but failed to provide proper coordination during changes of load,generation,and *** the meantime,with the increasing number of DS relays,the total relay operating time tends to ***,this paper proposes a protection scheme based on the optimal deployment of conventional and dual-setting rate of change of voltage(DS-ROCOV)relays in distribution *** holds true for varying network topologies and is unaffected by variations in load and *** objective of the proposed scheme is to ensure reliable and efficient protection against faults in distribution systems by minimizing the overall operating time with the optimal number of DS-ROCOV *** proposed protection scheme’s performance is evaluated for different coordination time interval values as well as in different microgrid *** paper outlines the design and implementation of the proposed protection scheme which is validated on the modified IEEE 14-bus system using simulations in Matlab/Simulink.

关键词： Coordination time interval DS-ROCOV relay multi-objective optimization optimal-deployment protection coordination

Biorenewable materials for water remediation: The central role of cellulose in achieving sustainability

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Journal of Bioresources and Bioproducts 2024年第3期9卷 253-282页

作者： Kirti Mishra Samarjeet singh Siwal Thandiwe Sithole Nirankar singh Phil Hart Vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Haryana 133207India Department of Chemical Engineering University of JohannesburgDoornfontein 2088South Africa Biorefining and Advanced Materials Research Center Scotland’s Rural CollegeEdinburgh EH93JGUnited Kingdom Renewable and Sustainable Energy Research Centre Technology Innovation InstituteAbu Dhabi 9639United Arab Emirates School of Engineering University of Petroleum&Energy StudiesDehradun 248007India

As the population increases and manufacturing grows,greenhouse gas and other harmful emissions *** with chemicals such as dyes,pesticides,pharmaceuticals,oil,heavy metals or radionuclides,wastewater purification has become an urgent *** technologies exist that can remove these contaminants from wastewater sources,but they often demand high energy and/or high cost,and in some cases produce contaminant laden sludge that requires safe *** need for methods which are less capital intensive,less operationally costly and more environmentally friendly is ***-based materials have emerged as promising candidates for wastewater treatment due to their renewability,low cost,biodegradability,hydrophilicity,and antimicrobial *** this review article,we focussed on developing sustainable and biodegradable cellulose-based materials for wastewater *** article deals with cellulose-based materials’scope and their conversion into valuable products like hydrogel,aerogel,cellulose composites,and *** cellulose-based materials have no harmful environmental impact and are *** modified cellulose-based materials applying as membrane,adsorbent,sorbent,and beads to purify the wastewater were ***,the challenges and future prospects of cellulose-based materials for wastewater treatment were considered,emphasizing their potential to be sustainable and eco-friendly alternatives to traditional materials used in wastewater treatment.

关键词： Cellulose Wastewater treatment Hydrogel Nanocrystal Cellulose membrane