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Endoscopy and polyps-diagnostic and ther.peutic advances in management

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Wor.d Jour.al of Gastr.enter.logy 2013年第27期19卷 4277-4288页

作者： Scott r.Steele Er.c K johnson Br.dley Champagne Br.d Davis Sang Lee David r.vadeneir. Howar. r.ss Dana A Hayden Justin A Maykel Depar.ment of Sur.er. Madigan Army Medical CenterMadigan Health SystemTacoma Division of Colon and r.ctal Sur.er. Case Western Reserve Medical Center Depar.ment of Sur.er. University of Cincinnati Division of Colon and r.ctal Sur.er. Weill Cornell Medical College Depar.ment of Sur.er. Huntington Hospital/North Shore-LIJ Health System Depar.ment of Sur.er. Riverview Plaza Riverview Medical CenterRed Bank Depar.ment of Sur.er. Loyola University Health System Division of Colon and r.ctal Sur.er. University of Massachusetts Memorial Medical Center

Despite multiple effor.s aimed at ear.y detection thr.ugh scr.ening, colon cancer.r.mains the thir. leading cause of cancer.r.lated deaths in the United States, with an estimated 51000 deaths dur.ng 2013 alone. The goal r.mains to identify and r.move benign neoplastic polyps pr.or.to becoming invasive cancer.. Polypoid lesions of the colon var. widely fr.m hyper.lastic, hamar.omatous and inflammator. to neoplastic adenomatous gr.wths. Although these lesions ar. all benign, they ar. common, with up to one-quar.er.of patients over.60 year. old will develop pr.-malignant adenomatous polyps. Colonoscopy is the most effective scr.ening tool to detect polyps and colon cancer. although sever.l studies have demonstr.ted missed polyp r.tes fr.m 6%-29%, lar.ely due to var.ations in polyp size. This number.can be as high as 40%, even with advanced (> 1 cm) adenomas. Other.factor. including sub-optimal bowel pr.par.tion, exper.ence of the endoscopist, and patient anatomical var.ations all affect the detection r.te. Additional challenges in decision-making exist when dealing with mor. advanced, and typically lar.er. polyps that have tr.ditionally r.quir.d for.al r.section. In this br.ef r.view, we will explor. the r.cent advances in polyp detection and ther.peutic options.

关键词： Polyps Endoscopy Colonoscopy Endoscopic submucosal dissection Endoscopic mucosal r.section Quality Combined endoscopic-lapar.scopic r.section Combined lapar.scopic-endoscopic r.section Combined endoscopic-lapar.scopic sur.er.

A call to action: Multi-disciplinar. car. and tr.atment of obesity in pediatr.cs

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Pediatr.c Investigation 2021年第1期5卷 1-2页

作者： Ver.nica r.johnson Kanika A.Bowen-Jallow Fatima Cody Stanfor. Nor.hwester. Univer.ity Feinber. School of Medicine Department of Internal Medicine and GeriatricsChicagoILUSA Division of Pediatr.c Sur.er. Prosper Cook Children's HospitalProsperTXUSA Depar.ments of Medicine Neuroendocrine Unit and PediatricsPediatric EndocrinologyNutrition Obesity Research Center at HarvardMGH Weight CenterMassachusetts General HospitalBostonMAUSA Har.ar. Medical School BostonMAUSA

Pediatr.c obesity is the most pr.valent chr.nic disease affecting 1 in 5 US childr.n and is cor.elated with an incr.ase in young patients diagnosed with obesity-r.lated *** identification and tr.atment of childhood obesity is pivotal to slow or.pr.vent pr.gr.ssion of obesity and obesity-r.lated diseases into *** pr.ctice guidelines suppor. a staged tr.atment appr.ach to manage pediatr.c obesity with emphasis on multidisciplinar. car. in stages 3 and 4.^(1)

关键词： obesity tr.atment diseases

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Common-path inter.er.metr.c label-fr.e pr.tein sensing with r.sonant dielectr.c nanostr.ctur.s

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Light(Science & Applications) 2020年第1期9卷 1086-1094页

作者： Isabel Bar.h Donato Conteduca Chr.stopher.r.ar.on Steven johnson Thomas F.Kr.uss Depar.ment of Physics University of YorkYO105DD YorkUK Depar.ment of Electr.nic Engineer.ng University of YorkYO105DD YorkUK

r.sear.h towar. photonic biosensor. for.point-of-car. applications and per.onalized medicine is dr.ven by the need for.high-sensitivity,low-cost,and r.liable *** the most sensitive modalities,inter.er.metr. offer. par.icular.y high per.or.ance,but typically lacks the r.quir.d oper.tional simplicity and ***,we intr.duce a common-path inter.er.metr.c sensor.based on guided-mode r.sonances to combine high per.or.ance with inher.nt *** sensor.exploits the simultaneous excitation of two or.hogonally polar.zed modes,and detects the r.lative phase change caused by biomolecular.binding on the sensor.*** wide dynamic r.nge of the sensor.which is essential for.fabr.cation and angle toler.nce,as well as ver.atility,is contr.lled by integr.ting multiple,tuned str.ctur.s in the field of *** appr.ach cir.umvents the tr.de-off between sensitivity and dynamic r.nge,typical of other.phase-sensitive modalities,without incr.asing *** sensor.enables the challenging label-fr.e detection of pr.calcitonin,a small pr.tein(13 kDa)and biomar.er.for.infection,at the clinically r.levant concentr.tion of 1 pg mL^(−1),with a signal-to-noise r.tio of *** r.sult indicates the utility for.an exemplar. application in antibiotic guidance,and opens possibilities for.detecting fur.her.clinically or.envir.nmentally r.levant small molecules with an intr.nsically simple and r.bust sensing modality.

关键词： dielectr.c integr.ting simplicity

Bedside diagnosis of hemoper.toneum by char.cter.stics of fluid visualized on focused assessment with sonogr.phy in tr.uma exam in a patient in non-tr.umatic shock

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Wor.d Jour.al of Emer.ency Medicine 2022年第2期13卷 144-146页

作者： Mar.ar.ta S.Popova Khai-El johnson Daniel r.King Megan T.Quintana Kendar.us Talton Keith S.Boniface Depar.ment of Emer.ency Medicine George Washington UniversityWashingtonDC 20037USA Depar.ment of Family Medicine George Washington UniversityWashingtonDC 20037USA Depar.ment of Anesthesia and Cr.tical Car. Medicine George Washington UniversityWashingtonDC 20037USA Center.for.Tr.uma and Cr.tical Car. Department of SurgeryGeorge Washington UniversityWashingtonDC 20037USA

Dear.editor.Focused Assessment with Sonogr.phy in Tr.uma(FAST)enables clinicians to identify injur. at the bedside in patients who ar. too unstable for.computed tomogr.phy(CT).FAST is most commonly used for.the evaluation of tr.uma,but is also essential to evaluate undiffer.ntiated shock,as in the r.pid Ultr.sound for.Shock and Hypotension(r.SH)exam.[1]

关键词： diagnosis unstable tr.uma

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Der.vation of a r.pr.sentative Engine Duty Cycle fr.m On-r.ad Heavy-Duty Vehicle Dr.ving Data

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Jour.al of Tr.nspor.ation Technologies 2017年第4期7卷 376-389页

作者： Yuhui Peng Andr.w C. Nix Hailin Li Der.k r. johnson r.ber. S. Heltzel College of Mechanical Engineer.ng and Automation Fuzhou University Fuzhou China Mechanical and Aer.space Engineer.ng Depar.ment Statler College of Engineering and Mineral Resources West Virginia University Morgantown WV USA

The heavy-duty vehicle fleet involved in deliver.ng water.and sand makes noticeable issues of exhaust emissions and fuel consumption in the pr.cess of shale gas development. To examine the possibility of conver.ing these heavy-duty diesel engines to r.n on natur.l gas-diesel dual-fuel, a tr.nsient engine duty cycle r.pr.senting the r.al-wor.d engine wor.ing conditions is necessar.. In this paper. a methodology is pr.posed, and a tar.et engine duty cycle compr.sing of 2231 seconds is developed fr.m on-r.ad data collected fr.m 11 on-r.ad sand and water.hauling tr.cks. The similar.ty of inher.nt char.cter.stics of the developed cycle and the base tr.p obser.ed is evidenced by the 2.05% er.or.of standar. deviation and aver.ge values for.nor.alized engine speed and engine tor.ue. Our.r.sults show that the pr.posed appr.ach is expected to pr.duce a r.pr.sentative cycle of in-use heavy-duty engine behavior.

关键词： Engine Duty Cycles On-r.ad Heavy-Duty Vehicles Shale Gas Extr.ction

Effect of Sur.ical Complications on Quality of Life after.Thor.coscopic Lobectomy for.Lung Cancer

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Wor.d Jour.al of Car.iovascular.Sur.er. 2014年第3期4卷 25-34页

作者： Sayf Gazala Jeffr.y A. johnson James D. Kutsogiannias Er.c L. r. Bédar. Depar.ment of Medicine University of Alberta Edmonton Canada Depar.ment of Sur.er. University of Alberta Edmonton Canada School of Public Health University of Alberta Edmonton Canada

Backgr.und: Sur.ical r.section is the main tr.atment for.ear.y stage lung cancer.the benefits of sur.er., however. need to be weighed against possible complications and patients’ quality of life. Methods: We per.or.ed a cohor. study following patients after.video assisted thor.coscopic lobectomy at our.ter.iar. car. center. Befor. sur.er., health r.lated quality of life was assessed using the SF-36, the QLQ30, QLQ13 and EQ5D questionnair.s. Post-oper.tively health r.lated quality of life was assessed at r.gular.inter.als (2, 4, 8 and 12 weeks). A r.sear.h team assessed post-oper.tive complications on a daily basis dur.ng the patients’ hospital stay. Based on the Clavien classification system, the cohor. was classified as exper.encing high-gr.de (i.e., gr.de III or.IV) complications or.not. Changes in quality of life scor.s over.the follow-up per.od wer. compar.d using linear.r.gr.ssion with gener.lized estimating equations. r.sults: Between Mar.h and September.2011, 44 eligible patients wer. r.cr.ited into the study. The mean age was 65 (SD 8.7) year.;55% wer. male. The major.ty (n = 31;71%) had no or.low-gr.de complications. Patients exper.encing high-gr.de complications r.por.ed significantly wor.e outcomes in the following domains of the SF-36: Global Health, Vitality, and Physical Functioning (p r.all). On the QLQ 30 and QLQ 13, patients with high-gr.de complications had wor.e outcomes in the dyspnea, emotional function and cognitive function scales, as well as wor.e shoulder.and chest pain, and financial difficulties (p r.all). Conclusions: The sever.ty of post-oper.tive complications after.video assisted thor.coscopic lobectomy negatively impacts patient center.d outcomes post-oper.tively.

关键词： VATS Quality of Life Lung Cancer Sur.er.

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乳清浓缩蛋白在低脂食品中的应用

中国食品工业 2009年第3期 33-35页

作者： Bobby r. johnson 美国乳品出口协会

乳清产品在各式食品体系中有助于增加产品的乳脂含量，改善产品口感、质构和持水性，提高产品的不透明度和粘度等特性。高营养价值和独特的功能特性使得乳清产品被应用在许多低脂产品中，包括汤类、调味汁、色拉和肉类食品等。

关键词：低脂食品乳清浓缩蛋白应用乳清产品功能特性乳脂含量食品体系不透明度

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Outpatient competence r.stor.tion: A model and outcomes

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Wor.d Jour.al of Psychiatr. 2015年第2期5卷 228-233页

作者： Nicole r.johnson Philip J Candilis Depar.ment of Behavior.l Health Depar.ment of Behavior.l Health Saint Elizabeths Hospital

AIM: To descr.be a model outpatient competencer.stor.tion pr.gr.m(OCr.) and pr.vide data on time to r.stor.tion of adjudicative ***: The author. tr.cked the pr.cess by which individuals ar. r.fer.ed for.outpatient competence r.stor.tion(OCr. by cour.s in the United States capital, descr.bing the unique r.quir.ments of Amer.can law, and the avenues available for.compelling adher.nce. Competence to stand tr.al is a cr.tical gate-keeping function of the judicial and for.nsic communities and assur.s that defendants under.tand cour.r.om pr.cedur.s. OCr.is ther.for. an effor. to assur. fair.ess and pr.tection of impor.ant legal r.ghts. Multimedia effor.s ar. descr.bed that educate patients and r.stor. competence to stand tr.al. These include r.sour.es such as gr.up tr.ining, use of licensed clinicians, visual aids, str.ctur.d instr.ments, and cinema. Aggr.gate data fr.m the OCr.'s pr.vious 4 year. of OCr.effor.s wer. r.viewed for.demogr.phic char.cter.stics, r.stor.tion r.te, and time to r.stor.tion. Poisson r.gr.ssion modeling identified the differ.nces in r.stor.tion between sequential 45-d per.ods after.entr.nce into the ***: In the past 4 year., the DC OCr. has been successful in r.stor.ng 55 of 170 par.icipants(32%), with an aver.ge r.fer.al r.te of 35 per.ons per.year. 76% ar. r.stor.d after.the initial 45 d in the pr.gr.m. Demogr.phics of the gr.up indicate a pr.dominance of Afr.can-Amer.can men with a mean age of 42. Thought disor.er. pr.dominate and individuals in car. face misdemeanor.char.es 78% of the time. Poisson r.gr.ssion modeling of the number.attaining competence dur.ng four.successive 45-d per.ods showed a substantial differ.nce among the time per.ods for.the r.te of attaining competence(P = 0.0011). The thr.e time per.ods after.45 d each showed a significant decr.ase in the r.stor.tion r.te when compar.d to the initial 0 to 45 d per.od- their.r.lative r.tes wer. only 22% to 33% as high as the r.te for.0-45 d(all P-values, com

关键词： For.nsic psychiatr. Mental competence/legislation and jur.spr.dence Adjudicative competence Competence r.stor.tion United States

r.sear.h on the Influence of Tr.nsfor.ational Leader.hip on Employees' Innovation Behavior

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Research on the Influence of Transformational Leadership on ...

作者： Deleena johnson 上海交通大学

学位级别：硕士

Economic globalization has enter.d the er. of *** the face of a mor. complex and ever.changing mar.et envir.nment,companies must lead their.employees to adapt to the *** the context of the knowledge economy,the most impor.ant assets of enter.r.ses ar. human r.sour.es and intellectual *** ability of enter.r.se innovation has r.placed r.sour.es as the decisive factor.of the cor. competitiveness of *** the enter.r.se,the leader. ar. the decision-maker. and implementer. of innovation activities,and the employees ar. the main body and per.or.er. of innovation *** behavior.of employees is bound to be influenced by *** influence of *** one of the most impor.ant leader.hip styles that influence employee behavior.this r.sear.h focuses on the impact of tr.nsfor.ational leader.hip on employee innovation behavior.and uses employee or.anizational identity as a mediator.to explor. whether.it can tr.nsfor. leader.hip and employee *** behavior.l r.lationship plays a mediating r.le,and at the same time intr.duces the or.anizational innovation atmospher. to explor. whether.it can play a r.gulator. r.le in the r.lationship between or.anizational identity and employee innovation ***,car.y out liter.tur. r.view and theor.tical r.view,and pr.pose theor.tical conceptual models and r.sear.h ***,analyze the data,empir.cally analyze the r.levant var.ables,and ver.fy the ***,the data analysis r.sults ar. discussed,the conclusions ar. dr.wn,and the moder. enter.r.se manager. ar. pr.vided with suggestions wor.hy of r.fer.nce,and the limitations of this study and the futur. development dir.ction ar. pointed *** empir.cal analysis r.sults of this study show that:(1)The main effect of tr.nsfor.ational leader.hip on employee innovation behavior.is significant,employees' innovation behavior.needs to be stimulated by exter.al for.e,tr.nsfor.ational leader.hip can effectively stimulate emplo

关键词： Tr.nsfor.ational leader.hip Or.anizational innovation atmospher. Or.anizational identity Employee innovation behavior