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Journal of Environmental Sciences 2019年第1期31卷 64-72页

作者： NikAthirah Yusoff Soon-An Ong li-Ngee Ho Yee-Shian Wong Farah Naemah Mohd Saad WanFadhilah Khalik sin-li lee School of Environmental Engineering University Malaysia Perlis School of Materials Engineering University Malaysia Perlis

Hybrid growth microorganisms in sequencing batch reactors have proven effective for treating the toxic compound phenol, but the toxicity effect under different toxicity conditions has rarely been discussed. Therefore, the performance of the HG-SBR under toxic, acute and chronic organic loading can provide the overall operating conditions of the system. Toxic organic loading(TOL) was monitored during the first 7 hr while introducing50 mg/L phenol to the system. The system was adversely affected with the sudden introduction of phenol to the virgin activated sludge, which caused a low degradation rate and high dissolved oxygen consumption during TOL. Acute organic loading(AOL) had significant effects at high phenol concentrations(600, 800 1000 mg/L). The specific oxygen uptake rate(SOUR) gradually decreased to 4.9 mg O_2/(g MLVSS·hr) at 1000 mg/L of phenol compared to 12.74 mg O_2/(g MLVSS·hr) for 200 mg/L of phenol. The HG-SBR was further monitored during chronic organic loading(COL) over 67 days. The effects of organic loading were more apparent at 800 mg/L and 1000 mg/L phenol concentrations, as the removal range was between 22%–30% and 18%–46% respectively, which indicated the severe effects of COL.

关键词： Toxic organic loading Acute organic loading Chronic organic loading Phenol Sequencing batch reactor

Tailoring light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection

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Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao li Hong Zhou Zhihao Ren Cheng Xu Chengkuo lee Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intelligent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

Plasmonic nanoantennas provide unique opportunities for precise control of light–matter coupling in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems realized so far suffer from the obstacles of low sensitivity,narrow bandwidth,and asymmetric Fano resonance ***,we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient(μ)(OC-Hμresonator)by precisely controlling the radiation loss channel,the resonator-oscillator coupling channel,and the frequency detuning *** observed a strong dependence of the sensing performance on the coupling state,and demonstrated that OC-Hμresonator has excellent sensing properties of ultra-sensitive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules,trace detection,and protein secondary structure analysis using a single array(array size is 100×100μm^(2)).In addition,with the assistance of machine learning,mixture classification,concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%.Finally,we demonstrated the potential of OC-Hμresonator for SARS-CoV-2 *** findings will promote the wider application of SEIRA technology,while providing new ideas for other enhanced spectroscopy technologies,quantum photonics and studying light–matter interactions.

关键词： Plasmonic nanoantennas light-matter interaction Surface-enhanced infrared absorption Overcoupled Biosensing

A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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Nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian Guo Kunpeng li Wei Yue Nam‑Young Kim Yang li Guozhen Shen Jong‑Chul lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

Preparation of Polyester Polyol from Epoxidized Palm Olein

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Chinese Journal of Chemistry 2011年第4期29卷 840-846页

作者： lee, Choy sin lee, Song Cang Pharmaceutical Chemistry Department International Medical University No 126 Jalan 19/155B Bukit Jalil 57000 KL Malaysia Biomedical Engineering Department Faculty of Engineering University of Malaya 50603 KL Malaysia

In this work, polyester polyols with high weight average molecular weight （Mw）（Mw= 10000-15000） were prepared from epoxidized palm olein （EPOo） and a series of dicarboxylic acids （C6-C12） at elevated temperature under non-catalyzed condition. The optimal reaction conditions were determined as 180 ℃ for 4 h. Longer carbon chain length of dicarboxylic acids was more reactive when reacted with EPOo. The physical appearance of the product was observed as liquid at room temperature. This palm oil-based polyester polyol is proposed as starting material for flexible polyurethane. For reaction monitoring purposes, FTIR was used while 1H NMR analysis was carried out to characterize the important functional groups of the products. The effects of reaction time and temperature on the Mw of the reaction mixture were also studied by GPC.

关键词： dicarboxylic acids epoxidized palm olein polyester poyol

Development of site suitability analysis system for riverbank filtration

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Water Science and Engineering 2010年第1期3卷 85-94页

作者： Sang-il lee Sang-sin lee Department of Civil and Environmental Engineering Dongguk University

Site selection plays a crucial role in riverbank filtration for sustainable water availability and quality. Choosing the most appropriate from among multiple candidate sites requires a complex procedure, involving many tangibles and intangibles. In this study, the Analytic Hierarchy Process （AHP）, which selects the optimal alternative by hierarchically classifying various attributes and then quantifying the importance of each attribute, was used to prioritize candidate locations for riverbank filtration. A GIS-based computer program was developed to automate the assessment process. The developed software was applied to the Han River in Korea. Analysis of four candidate sites reveals that a site that has better water quality and connectivity to the neighboring purification facility is more suitable than other locations.

关键词： riverbankfiltration AHP site suitability," Han River

Tunable liquid crystal grating based holographic 3D display system with wide viewing angle and large size

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light(Science & Applications) 2022年第7期11卷 1575-1584页

作者： Yi-Long li Nan-Nan li Di Wang Fan Chu sin-Doo lee Yi-Wei Zheng Qiong-Hua Wang School of Instrumentation and Optoelectronic Engineering Beihang UniversityBeijingChina Display Technology Research Center Seoul National UniversityGwanak-guSeoulRepublic of Korea

As one of the most ideal display approaches,holographic 3-dimensional(3D)display has always been a research hotspot since the holographic images reproduced in such system are very similar to what humans see the actual ***,current holographic 3D displays suffer from critical bottlenecks of narrow viewing angle and small ***,we propose a tunable liquid crystal grating-based holographic 3D display system with wide viewing angle and large *** tunable liquid crystal grating,providing an adjustable period and the secondary diffraction of the reconstructed image,enables to simultaneously implement two different hologram generation methods in achieving wide viewing angle and enlarged size,*** using the secondary diffraction mechanism of the tunable liquid crystal grating,the proposed system breaks through the limitations of narrow viewing angle and small size of holographic 3D *** proposed system shows a viewing angle of 57.4°,which is nearly 7 times of the conventional case with a single spatial light modulator,and the size of the reconstructed image is enlarged by about *** proposed system will have wide applications in medical diagnosis,advertising,education and entertainment and other fields.

关键词： holographic system angle

PGLYRP1 protein as a novel mediator of cellular dialogue in neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 1993-1994页

作者： Anup Bhusal Won-Ha lee Kyoungho Suk Department of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea BK21 Plus KNU Biomedical Convergence Program Department of Biomedical ScienceSchool of MedicineKyungpook National UniversityDaeguRepublic of Korea School of life Sciences BK21 plus KNU Creative BioResearch GroupKyungpook National UniversityDaeguRepublic of Korea Brain Science and Engineering Institute Kyungpook National UniversityDaeguRepublic of Korea

Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.

关键词： inflammation considerably

single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong lee Su Bin lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael J.lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Color liquid crystal grating based color holographic 3D display system with large viewing angle

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light(Science & Applications) 2024年第1期13卷 103-112页

作者： Di Wang Yi-Long li Fan Chu Nan-Nan li Zhao-Song li sin-Doo lee Zhong-Quan Nie Chao liu Qiong-Hua Wang School of Instrumentation and Optoelectronic Engineering Beihang UniversityBeijing 100191China State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijing 100191China Display Technology Research Center Seoul National UniversityGwanak-ro 1Gwanak-guSeoul 08826Republic of Korea Key Lab of Advanced Transducers and Intelligent Control System Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China

Holographic 3D display is highly desirable for numerous applications ranging from medical treatments to military ***,it is challenging to simultaneously achieve large viewing angle and high-fidelity color reconstruction due to the intractable constraints of existing ***,we conceptually propose and experimentally demonstrate a simple and feasible pathway of using a well-designed color liquid crystal grating to overcome the inevitable chromatic aberration and enlarge the holographic viewing angle,thus enabling large-viewing-angle and color holographic 3D *** use of color liquid crystal grating allows performing secondary diffraction modulation on red,green and blue reproduced images simultaneously and extending the viewing angle in the holographic 3D display *** principle,a chromatic aberration-free hologram generation mechanism in combination with the color liquid crystal grating is proposed to pave the way for on such a superior holographic 3D *** proposed system shows a color viewing angle of~50.12°,which is about 7 times that of the traditional system with a single spatial light *** work presents a paradigm for achieving desirable holographic 3D display,and is expected to provide a new way for the wide application of holographic display.

关键词： holographic angle crystal