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Objective electrophysiological contrast sensitivity with monofocal and multifocal intraocular lenses:a prospective clinical study

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Annals of Eye Science 2018年第1期3卷 136-146页

作者： Salvatore Cillino Giovanni Cillino simona di naro Aissa Iggui Viviana Firpo Girolamo Maniscalco Alessandra Casuccio Department of Experimental Biomedicine and Clinical Neuroscience Ophthalmology SectionUniversity of PalermoPalermoItaly Department of Sciences for Health Promotion and Mother-Child Care“G.D’Alessandro” University of PalermoPalermoItaly

Background:To compare objective electrophysiological contrast sensitivity function(CSF)in patients implanted with either multifocal intraocular lenses(MIOLs)or monofocal intraocular lenses(IOLs)by pattern reversal visual evoked potentials(prVEP)***:Fourty-five cataract patients were randomly allocated to receive bilaterally:apodized diffractive-refractive Alcon Acrysof MIOL(A),full diffractive AMO Tecnis MIOL(B)or monofocal Alcon Acrysof IOL(C).Primary outcomes:1-year differences in objective binocular CSF measured by prVEP with sinusoid grating stimuli of 6 decreasing contrast levels at 6 spatial *** outcomes:psychophysical CSF measured with VCTS-6500,photopic uncorrected distance(UDVA),and mesopic and photopic uncorrected near and intermediate visual acuities(UNVA and UIVA respectively).Results:Electrophysiological CSF curve had an inverted U-shaped morphology in all groups,with a biphasic pattern in Group *** A showed a lower CSF than group B at 4 and 8 cpd,and a lower value than group C at 8 *** CSF in group A exhibited a lower value at 12 cpd than group *** photopic and mesopic UNVA and UIVA were worse in monofocal group compared to the multifocal *** UNVA and UIVA were better in group ***:Electrophysiological CSF behaves differently depending on the types of multifocal or monofocal *** may be related to the visual acuity under certain conditions or to IOL *** objective method might be a potential new tool to investigate on MIOL differences and on subjective device-related quality of vision.

关键词： Electrophysiological contrast sensitivity visual evoked potentials(VEPs) multifocal intraocular lens(MIOLs) prospective clinical study

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