检索结果-南通市图书馆

Mechanisms of retinal neuroprotection of calcium dobesilate：therapeutic implications

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第10期12卷 1620-1622页

作者： Olga simó-Servat Cristina Solà-Adell Patricia Bogdanov Cristina Hernández Rafael simó Diabetes and Metabolism Research Unit Vall d'Hebron Research InstituteCIBERDEM(Instituto de Salud CarlosⅢ)BarcelonaSpain

Current treatments for diabetic retinopathy （DR） are based on laser photocoagulation and intravitreal injections of corti- costeroids or anti-vascular endothelial growth factor （VEGF） agents. These treatments are applicable only at advanced stages of the disease. In addition, they are expensive, require a vitreo- retinal specialist and are associated with significant adverse ef- fects. Therefore, new pharmacological treatments for the early stages of the disease are needed.

关键词： Ca Mechanisms of retinal neuroprotection of calcium dobesilate:therapeutic implications

Lighting transfer across multiple views through local color transforms

在线全文

学校读者我要写书评

暂无评论

Computational Visual Media 2017年第4期3卷 315-324页

作者： Qian Zhang Pierre-Yves Laffont Terence sim Nanyang Technological University ETH Zurich National University of Singapore

We present a method for transferring lighting between photographs of a static scene. Our method takes as input a photo collection depicting a scene with varying viewpoints and lighting *** cast lighting transfer as an edit propagation problem, where the transfer of local illumination across images is guided by sparse correspondences obtained through multi-view stereo. Instead of directly propagating color, we learn local color transforms from corresponding patches in pairs of images and propagate these transforms in an edge-aware manner to regions with no correspondences. Our color transforms model the large variability of appearance changes in local regions of the scene, and are robust to missing or inaccurate correspondences. The method is fully automatic and can transfer strong shadows between images. We show applications of our image relighting method for enhancing photographs, browsing photo collections with harmonized lighting, and generating synthetic time-lapse sequences.

关键词： relighting photo collection time-lapse image editing

Approximate Analytical Solutions for a Class of Laminar Boundary-Layer Equations

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2007年第7期24卷 1981-1984页

作者： Seripah Awang Kechil Ishak Hashim sim Slaw Jiet Department of Mathematics Univer'siti Teknologi MARA 40450 Shah Alam Selangor Malaysia School of Mathematical Sciences Universiti Kebangsaan Malaysia 43600 UKM Bangi Selangor Malaysia

A simple and efficient approximate analytical technique is presented to obtain solutions to a class of two-point boundary value similarity problems in fluid mechanics. This technique is based on the decomposition method which yields a genera/analytic solution in the form of a convergent infinite series with easily computable terms. Comparative study is carried out to show the accuracy and effectiveness of the technique.

关键词： ADOMIAN DECOMPOSITION METHOD COMPARING NUMERICAL-METHODS GA-SB SYSTEM MARANGONI CONVECTION UNBOUNDED DOMAIN ALGORITHM SURFACE FLOWS

SMINER:Detecting Unrestricted and Misimplemented Behaviors of Software Systems Based on Unit Test Cases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第5期75卷 3257-3274页

作者： Kyungmin sim Jeong Hyun Yi Haehyun Cho School of Software Soongsil UniversitySeoul06978Korea

Despite the advances in automated vulnerability detection approaches,security vulnerabilities caused by design flaws in software systems are continuously appearing in real-world *** security design flaws can bring unrestricted and misimplemented behaviors of a system and can lead to fatal vulnerabilities such as remote code execution or sensitive data ***,it is an essential task to discover unrestricted and misimplemented behaviors of a ***,it is a daunting task for security experts to discover such vulnerabilities in advance because it is timeconsuming and error-prone to analyze the whole code in ***,most of the existing vulnerability detection approaches still focus on detecting memory corruption bugs because these bugs are the dominant root cause of software *** paper proposes SMINER,a novel approach that discovers vulnerabilities caused by unrestricted and misimplemented *** first collects unit test cases for the target system from the official ***,preprocess the collected code *** uses pre-processed data to show the security policies that can occur on the target system and creates a test case for security policy *** demonstrate the effectiveness of SMINER,this paper evaluates SMINER against Robot Operating System(ROS),a real-world system used for intelligent robots in Amazon and controlling satellites in National Aeronautics and Space Administration(NASA).From the evaluation,we discovered two real-world vulnerabilities in ROS.

关键词： Security vulnerability test case generation security policy test robot operating system vulnerability assessment

Oxidative coupling of methane over LaAlO3 perovskite catalysts prepared by a co-precipitation method: Effect of co-precipitation pH value

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2019年第8期28卷 1-8,I0001页

作者： Yujin sim Jihoon Yoo Jeong-Myeong Ha Ji Chul Jung Department of Chemical Engineering Myongji UniversityYongin 17058 Republic of Korea Clean Energy Research Center Korea Institute of Science and TechnologySeoul 02792 Republic of Korea

Oxidative coupling of methane(OCM) was conducted over LaAlO3X catalysts that were prepared by a coprecipitation method using different co-precipitation pH values(X = 6–10). The aim is to investigate the effect of p H values on the catalytic activity of La AlO3 catalysts in this reaction. The results showed that the co-precipitation pH value affected greatly on the formation of chemical species of precipitate precursors in the co-precipitation step, leading to different phases of the finally obtained LaAlO3 *** the co-precipitation pH value increased up to 8, the lanthanum-related phases such as La2 O3 and La(OH)3 were gradually formed as by-products, preventing the formation of LaAlO3 perovskite crystalline structure and facilitating the formation of oxygen vacancies on catalyst surface. However, at pH value of9 or higher, the lanthanum content in the precipitate precursor was increased greatly. Not LaAlO3 perovskite but lanthanum-related phases were developed as main phases, reducing their catalytic activities in this reaction. Among LaAlO3 catalysts, the one prepared at pH = 8 showed the highest C2 yield due to its well-developed oxygen vacancies and electrophilic lattice oxygen. Therefore, the co-precipitation pH value strongly affected the LaAlO3 catalyst activity in OCM reaction. A precious pH control should be required to prepare various perovskite catalysts for the OCM.

关键词： LaAlO3 Perovskite Oxidative coupling of methane Co-precipitation pH value

Marker-Based,3-D Adaptive Cartesian Grid Method for Multiphase Flow Around Irregular Geometries

在线全文

学校读者我要写书评

暂无评论

Communications in Computational Physics 2009年第1期5卷 1-41页

作者： Eray Uzgoren Jaeheon sim Wei Shyy Department of Mechanical Engineering Virginia Polytechnic Institute and State UniversityBlacksburgVA24060USA Department of Aerospace Engineering University of MichiganAnn ArborMI48109USA

Computational simulations of multiphase flow are challenging because many practical applications require adequate resolution of not only interfacial physics associated with moving boundaries with possible topological changes,but also around three-dimensional,irregular solid *** this paper,we highlight recent efforts made in simulating multiphase fluid dynamics around complex geometries,based on an Eulerian-Lagrangian *** approach uses two independent but related grid layouts to track the interfacial and solid boundary conditions,and is capable of capturing interfacial as well as multiphase *** particular,the stationary Cartesian grid with time dependent,local adaptive refinement is utilized to handle the computation of the transport equations,while the interface shape and movement are treated by marker-based triangulated surface meshes which freely move and interact with the Cartesian *** markers are also used to identify the location of solid boundaries and enforce the no-slip condition *** related to the contact line treatment,topological changes of multiphase fronts during merger or breakup of objects,and necessary data structures and solution techniques are also *** test cases including spacecraft fuel tank flow management and liquid plug flow dynamics are presented.

关键词： Multiphase flows irregular geometry interface tracking adaptive Cartesian grid non-conforming boundary methods contact line treatment

An analysis of first-time and repeat visitors to Korean national parks from 2007 and 2013

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2017年第12期14卷 2527-2539页

作者： yunseon choe michael a.schuett kyu-won sim department of tourism management college of hotel and tourism managementkyung hee university26Kyungheedae-roDongdaemun-guSeoul02447Republic of Korea department of recreation park and tourism sciencestexas a&m university600 John Kimbrough BirdCollege StationTex as 77843USA national park research institute korea national park serviceWonju 26441Republic of Korea

This paper examined visitors to Bukhansan National Park in Korea based on first-time and repeat visitation. Bukhansan National Park is Korea's most heavily visited national park with annual visitation of six million visitors in 2015. Data used in this article were collected on-site in the park in 2007 and 2013 by the Korea National Park Service(KNPS).The study variables included socio-demographics,travel behavior, motivation, and satisfaction with park attributes, services and facilities. Data were analyzed by each study year for first-time and repeat *** showed significant differences for both firsttime and repeat visitors on several socio-demographic,travel behavior, and motivation variables within each study year. For satisfaction with park attributes,facilities and services, first-time visitors were significantly different from repeat visitors on seven variables for both years. Implications are given regarding programs and services to improve visitor satisfaction and sustain the natural, cultural and historical resources at Bukhansan National Park and other national parks in Korea. Future research suggestions are provided to learn more about visitor characteristics, standards of quality and preferences in the national parks.

关键词： Bukhansan National Park Korean national parks Visitor behaviour Market segmentation Visitor satisfaction

PI3K/Akt/mTOR inhibitors in breast cancer

在线全文

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2015年第4期12卷 342-354页

作者： Joycelyn JX Lee Kiley Loh Yoon-sim Yap Department of Medical Oncology National Cancer Center Singapore

Activation of the phosphoinositide 3 kinase(PI3K)/Akt/mammalian target of rapamycin(mTOR) pathway is common in breast cancer. There is preclinical data to support inhibition of the pathway, and phase Ⅰ to Ⅲ trials involving inhibitors of the pathway have been or are being conducted in solid tumors and breast cancer. Everolimus, an mTOR inhibitor, is currently approved for the treatment of hormone receptor(HR)-positive, human epidermal growth factor receptor 2(HER2)-negative breast cancer. In this review, we summarise the efficacy and toxicity findings from the randomised clinical trials, with simplified guidelines on the management of potential adverse effects. Education of healthcare professionals and patients is critical for safety and compliance. While there is some clinical evidence of activity of mTOR inhibition in HR-positive and HER2-positive breast cancers, the benefits may be more pronounced in selected subsets rather than in the overall population. Further development of predictive biomarkers will be useful in the selection of patients who will benefit from inhibition of the PI3K/Akt/mTOR(PAM) pathway.

关键词： Breast cancer phosphoinositide 3 kinase(PI3K)/Akt/ mammalian target of rapamycin(mTOR) everolimus

Post-disaster Psychosocial Capacity Building for Women in a Chinese Rural Village

在线全文

学校读者我要写书评

暂无评论

International Journal of Disaster Risk Science 2019年第2期10卷 193-203页

作者： Timothy sim Jocelyn Lau Ke Cui Hsi-Hsien Wei Department of Applied Social Sciences The Hong KongPolytechnic UniversityHong KongChina World Health Organization Collaborating Centre forCommunity Health Services School of NursingThe HongKong Polytechnic UniversityHong KongChina School of Public Administration Sichuan UniversityChengdu610065China Department of Building and Real Estate The Hong KongPolytechnic UniversityHong KongChina

Mental health interventions following disasters have been criticized as individualistic, incomplete, and culturally insensitive. This article showcases the effects of a culturally relevant and sustainable psychosocial capacitybuilding project at the epicenter of the 2008 Wenchuan Earthquake. Specifically, the project focuses on women, a group that has received limited attention in post-disaster recovery in China. This qualitative research study(N = 14)sheds light on the characteristics and processes of the implementation of a post-disaster psychosocial intervention project in rural China. In addition, by adopting the Success Case Method as an evaluation approach, this study elucidates its effects on the psychological and social changes of the disaster victims. The findings capture five aspects of psychosocial changes: enriched daily life, better mood,enhanced self-confidence, increased willingness to socialize, and the provision of mutual help. This study hopes to encourage more culturally relevant and empowering practices for women in building their psychosocial capacity after disasters.

关键词： China Natural hazard-induced disasters Post-disaster recovery Psychosocial capacity building Success case method Women’ empowerment