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Improving wood volume predictions in dry tropical forest in the semi-arid Brazil

Journal of Arid Land 2020年第6期12卷 1046-1055页

作者： Robson B de LImA Patrícia A B BARRETO-GARCIA Alessandro de PAULA Jhuly E S PEREIRA Flávia F de CARVALhO silvio h m gomes Department of Forest Engineering State University of AmapáMacapá68900070Brazil Department of Forest Science State University of Southwest BahiaVitória da Conquista 45083900Brazil Universidade Federal de Lavras Lavras 37200900Brazil Universidade de São Paulo Piracicaba 13418900Brazil

The volumetric variability of dry tropical forests in Brazil and the scarcity of studies on the subject show the need for the development of techniques that make it possible to obtain adequate and accurate wood volume *** this study,we analyzed a database of thinning trees from a forest management plan in the Contendas de SincoráNational Forest,southwestern Bahia State,*** data set included a total of 300 trees with a trunk diameter ranging from 5 to 52 ***,validation and statistical selection of four volumetric models were *** to the difference in height values for the same diameter and the low correlation between both variables,we do not suggest models which only use the diameter at breast height(DBh)variable as a predictor because they accommodate the largest estimation *** comparing the best single entry model(hohenald-Krenn)with the Spurr model(best fit model),it is noted that the exclusion of height as a predictor causes the values of 136.44 and 0.93 for Akaike information criterion(AIC)and adjusted determination coefficient(R2 adj),which are poorer than the second best model(Schumacher-hall).Regarding the minimum sample size,errors in estimation(root mean square error(RmSE)and bias)of the best model decrease as the sample size increases,especially when a larger number of trees with DBh≥15.0 cm are randomly *** sampling by diameter class produces smaller volume prediction errors than random sampling,especially when considering all *** summary,the Spurr and Schumacher-hall models perform *** models suggest that the total variance explained in the estimates is not less than 95%,producing reliable forecasts of the total volume with *** estimates indicate that the bias around the average is not greater than 7%.Our results support the decision to use regression methods to build models and estimate their parameters,seeking stratification strategies in diameter classes for the sample trees.

关键词： volume modeling minimal sample size Caatinga Spurr model forest management

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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3317-3329页

作者： Jennifer m.Colón-mercado Aranza I.Torrado-Tapias Iris K.Salgado Jose m.Santiago Samuel E.Ocasio Rivera Dina P.Bracho-Rincon Luis h.Pagan Rivera Jorge D.miranda Department of Physiology University of Puerto RicoMedical Sciences CampusSan JuanPRUSA National Institutes of health National Human Genome Research InstituteBethesdaMDUSA Universidad Central del Caribe School of MedicineBayamónPRUSA University of Puerto Rico Carolina CampusCarolinaPRUSA Institute of Neurobiology San JuanPRUSA

In addition to the loss of motor function,~60% of patients develop pain after spinal cord *** cellular-molecular mechanisms are not well understood,but the data suggests that plasticity within the rostral,epicenter,and caudal penumbra of the injury site initiates a cellularmolecular interplay that acts as a rewiring mechanism leading to central neuropathic *** can lead to the formation of new connections triggering abnormal sensory *** excitatory glutamate transporters are responsible for the reuptake of extracellular glutamate which makes them a critical target to prevent neuronal hyperexcitability and *** previous studies showed a sexually dimorphic therapeutic window for spinal cord injury after treatment with the selective estrogen receptor modulator *** this study,we investigated the anti-allodynic effects of tamoxifen in male and female rats with spinal cord *** hypothesized that tamoxifen exerts anti-allodynic effects by increasing the expression of glutamate transporters,leading to reduced hyperexcitability of the secondary neuron or by decreasing aberrant *** and female rats received a moderate contusion to the thoracic spinal cord followed by subcutaneous slow-release treatment of tamoxifen or matrix pellets as a control(placebo).We used von Frey monofilaments and the“up-down method”to evaluate mechanical *** treatment decreased allodynia only in female rats with spinal cord injury revealing a sexdependent *** expression profile of glutamatergic transporters(excitatory amino acid transporter 1/glutamate aspartate transporter and excitatory amino acid transporter 2/glutamate transporter-1)revealed a sexual dimorphism in the rostral,epicenter,and caudal areas of the spinal cord with a pattern of expression primarily on *** rodents showed a significantly higher level of excitatory amino acid transporter-1 expression while male rodents showed increased

关键词： allodynia central neuropathic pain EAAT-1/GLAST EAAT-2/GLT-1 glutamate transporters selective estrogen receptor modulator sexual dimorphism spinal cord injury trauma

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Neurogenesis in the hippocampus of adult humans: controversy “fixed” at last

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Neural Regeneration Research 2019年第11期14卷 1917-1918页

作者： Silene m.A. Lima Walace gomes-Leal Laboratory of Neurobiology Institute of Biological SciencesFederal University of ParaBelem-ParaBrazil Laboratory of Experimental Neuroprotection and Neuroregeneration Institute of Biological SciencesFederal University of ParaBelem-ParaBrazil

The presence of adult neurogenesis in the mammalian brain has been a theme of intense controversy for a long time since the original report by Altman and Das (1965). The scientific community, for about 30 years, has difficulties to accept that progenitor cells give rise to new neurons in some specific regions of the mammalian adult brain, the neurogenic niches (Kuhn et al., 1996;Doetsch et al., 1997, 1999).

关键词： Neurogenesis hippocampus mammalian brain

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Engineering carbon quantum dots for photomediated theranostics

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Nano Research 2018年第1期11卷 1-41页

作者： mahbub hassan Vincent G. gomes Alireza Dehghani Sara m. Ardekani School of Chemical and Biomolecular Engineering The University of Sydney NSW 2006 Australia

Carbon quantum dots （CQDs） have emerged as potential alternatives to classical metal-based semiconductor quantum dots （QDs） due to the abundance of their precursors, their ease of synthesis, high biocompatibility, low cost, and particularly their strong photoresponsiveness, tunability, and stability. Light is a versatile, tunable stimulus that can provide spatiotemporal control. Its interaction with CQDs elicits interesting responses such as wavelength-dependent optical emissions, charge/electron transfer, and heat generation, processes that are suitable for a range of photomediated bioapplications. The carbogenic core and surface characteristics of CQDs can be tuned through versatile engineering strategies to endow specific optical and physicochemical properties, while conjugation with specific moieties can enable the design of targeted probes. Fundamental approaches to tune the responses of CQDs to photo-interactions and the design of bionanoprobes are presented, which enable biomedical applications involving diagnostics and therapeutics. These strategies represent comprehensive platforms for engineering multifunctional probes for nanomedicine, and the design of QD probes with a range of metal-free and emer^in~ 2D materials.

关键词： carbon quantum dots nanobiophotonics therapeutics diagnostics nanomedicine

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Optimizing building retrofit through data analytics:A study of multi-objective optimization and surrogate models derived from energy performance certificates

Energy and Built Environment

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Energy and Built Environment 2024年第6期5卷 889-899页

作者： G.R.Araújo Ricardo gomes Paulo Ferrão m.Glória gomes IN+ DEMTécnico LisboaUniversidade de lisboaAv Rovisco PaisLisboa1049-001Portugal CERIS DECivilTécnico LisboaUniversidade de LisboaAv Rovisco PaisLisboa1049-001Portugal

The building stock is responsible for a large share of global energy consumption and greenhouse gas emissions,therefore,it is critical to promote building retrofit to achieve the proposed carbon and energy neutrality *** of the policies implemented in recent years was the Energy Performance Certificate(EPC)policy,which proposes building stock benchmarking to identify buildings that require ***,research shows that these mechanisms fail to engage stakeholders in the retrofit process because it is widely seen as a mandatory and complex *** study makes use of an EPC database to integrate machine learning techniques with multi-objective optimization and develop an interface capable of(1)predicting a building’s,or household’s,energy needs;and(2)providing the user with optimum retrofit solutions,costs,and return on *** goal is to provide an open-source,easy-to-use interface that guides the user in the building retrofit *** energy and EPC prediction models show a coefficient of determination(R2)of 0.84 and 0.79,and the optimization results for one case study EPC with a 2000€budget limit inÉvora,Portugal,show decreases of up to 60%in energy needs and return on investments of up to 7 in 3 years.

关键词： Building energy performance Building optimization multi-Objective surrogate models Building retrofitting

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Vegetation dynamics of ephemeral and perennial streams in mountainous headwater catchments

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Journal of mountain Science 2020年第7期17卷 1684-1695页

作者： Pattiyage I.A.gomes Onyx W.h.WAI Ganegoda K.DEhINI Department of Civil Engineering Faculty of EngineeringSri Lanka Institute of Information TechnologyMalabe10115Sri Lanka Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina

Ephemeral and perennial streams of mountainous catchments in Sabaragamuwa Province of Sri Lanka and hong Kong of China were studied for two years on vegetation *** year,sampling was conducted during a period when ephemeral streams had low surface *** was realized contiguously using belt *** standing crop biomass(hereafter biomass)of herbaceous vegetation in ephemeral channels was comparatively lower than perennials and so was the herb *** diversity showed a peak from 1.5 to 4.5 m from the centerline/thalweg of ephemeral and perennial *** of 24 herbs,only three were common for both.A peak herb biomass zone was observed in perennials in the same region where diversity *** ephemerals,herb biomass increased laterally up to^1.5 m,and was constant *** experiment results tallied with the field diversity observations of both stream types,and suggested that seed dispersion was the main reason for herb ***,it showed sapling emergence to be significantly higher in perennials than *** period of annual maximum monthly rainfall was a strong indicator of age of trees in ephemeral streams,and elucidated the possibility of hindcasting past flow *** conductivity was significantly high in ephemeral streams among all the water quality *** contents of the water nutrients were approximately the same in both stream *** recommending further studies on eco-hydrology of ephemerals,we recognize ephemeral streams to be valuable references in climate change studies due to their responsiveness and representativeness in long term hydrological changes.

关键词： Ephemeral streams herb diversity Biomass mountainous areas Perennial streams Sri Lanka

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Why microglia kill neurons after neural disorders? The friendly fire hypothesis

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Neural Regeneration Research 2019年第9期14卷 1499-1502页

作者： Walace gomes-Leal Laboratory of Experimental Neuroprotection and Neuroregeneration Institute of Biological Sciences Federal University of Para-Brazil

Neuroinflammation plays a fundamental role on the pathophysiology of acute and chronic neural *** activation is a major event following central nervous system inflammation displaying different phenotypes with beneficial and detrimental actions(a Janus face).The reason for this apparent duality is *** have previously shown that following experimental middle cerebral artery occlusion in the rat brain,microglia seem to support and impair adult neurogenesis in the same ischemic *** on these results,we raised the hypothesis that in the same pathologic environment,gradients of different ligands distributed over different anatomical niches might contribute to both detrimental and beneficial microglial *** ligands(“danger signals”)are released by dying cells and bind to microglial receptors in their *** of different microglial receptors induces downstream biochemical pathways culminating in a spectrum of microglial phenotypes like m1 and m2 and *** this paper,we first review the immune functions of microglia and the role of toll-like receptors on the fight against *** then briefly revise the dual role of microglia after neural *** then propose a novel hypothesis to explain the Janus face of microglia during the pathophysiology of central nervous system diseases:the“friendly fire hypothesis”.According to this idea“danger signals”or danger associated molecular patterns released by stressed,damaged and/or dying cells during stroke,trauma and other diseases might activate microglial pattern-recognition receptors(i.e.,toll like receptors)or other unidentified receptors normally activated by *** could activate the same genetic and biochemical machinery used by microglia to fight against pathogens even in the absence of *** to this notion,microglia may cause bystander neuronal damage with a kind of blind“friendly fire”,fighting against a non-existing infection during

关键词： stroke trauma Alzheimer’s disease neuroinflammation glial cells phenotypes degeneration neuroprotection

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Analysis of genetic relationship among Arbutus unedo L. genotypes using RAPD and SSR markers

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Journal of Forestry Research 2013年第2期24卷 227-236页

作者： Filomena gomes Rita Costa maria m. Ribeiro Elisa Figueiredo Jorge m. Canhoto CERNAS Departamento Florestal Escola Superior Agrária Coimbra INRB Instituto Nacional de Recursos Biológicos Departamento de Recursos Naturais e Desenvolvimento Sustentável Escola Superior Agrária Centre of Functional Ecology Department of Life Sciences University of Coimbra

The strawberry tree （Arbutus unedo L.） is an underutilized, drought tolerant, fire resistant species with a south western distribution in Europe, and with ecological and putative socio-economical impact in Portugal and mediterranean countries. Our aim was to develop an appropriate set of molecular markers to enable genetic diversity to be assessed and to fingerprint Arbutus unedo genotypes for breeding and conservation purposes in Portugal. Twenty-seven trees from a broad geographic range were screened with 20 random amplified polymorphic DNA （RAPD primers） and 11 microsatellite markers （SSR）. The RAPDs generated 124 bands, 57.3% of which were polymorphic, with an expected heterozygosity of 27%. We cross-amplified 11 SSR primers developed for Vaccinium spp., and 5 were found to be polymorphic in A. unedo, with 75% of expected heterozygosity, a number of alleles of 11.6, a null allele frequency of 7.6% and a polymorphic information content of 71%. Although the SSRs were more polymorphic and informative than the RAPDs, both markers displayed high genetic variability with the gathered data. No geographic pattern was observed in the genetic variation distribution based on both marker systems, and the lack of correlation between genetic and geographical matrices was confirmed by mantel tests. Likely, no correlation was found between pairwise SSR and RAPD band-sharing matrices. These results and their implications on A. unedo breeding and conservation programs are discussed.

关键词： Ericaceae fingerprinting geographic pattern molecular markers strawberry tree.

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Shielding AZ91D-1%Ca from corrosion through ultrasound melt treatment:A study for stent design

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Journal of magnesium and Alloys 2023年第8期11卷 2901-2915页

作者： I.V.gomes m.Pacheco m.Nienaber S.C.Neves D.mei A.Barros R.L.Reis J.L.Alves h.Puga CmEmS–Uminho University of MinhoGuimarãesPortugal LABBELS–Associate Laboratory BragaGuimarãesPortugal B's Research Group-Research Institute on Biomaterials Biodegradables and BiomimeticsUniversity of MinhoHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineAvepark-Parque de Ciência e TecnologiaBarco GuimarãesPortugal ICVS/3B's-PT Government Associate Laboratory BragaGuimarãesPortugal Institute of material and Process Design Helmholtz-Zentrum HereonGeesthacht 21502Germany School of materials Science and Engineering&henan Key Laboratory of Advanced magnesium Alloy Zhengzhou UniversityZhengzhou 450001China

magnesium-based materials show great potential for producing biodegradable stents,but their high corrosion rates are a *** study investigates whether ultrasound melt treatment can change the corrosion response of an extruded AZ91D-1.0%Ca(wt.%)in Earle's Balanced Salt Solution by tailoring the intermetallics'morphology in the as-extruded *** results showed that the wires from ultrasound-treated ingots corroded faster than non-treated ones in immersion for up to 6 *** trend shifted for longer periods,and ultrasound-treated material showed lower corrosion rates and uniform corrosion,while the non-treated material displayed localized corrosion *** testing of the wires demonstrated that immersion in EBSS lowered the tensile strength and elongation at fracture due to material degradation,regardless of the processing ***,this decline was sharper in the non-treated *** findings suggest that ultrasound melt processing can be a promising method for improving the corrosion resistance of magnesium-based materials,paving the way for their use in manufacturing biodegradable stents.

关键词： magnesium Ultrasound treatment Stent Corrosion mechanical properties

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Origami-Based Design for 4D Printing of 3D Support-Free hollow Structures

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Engineering 2022年第5期8卷 70-82页

作者： Bingcong Jian Frederic Demoly Yicha Zhang h.Jerry Qi Jean-Claude Andre Samuel gomes Laboratoire Interdisciplinaire Carnot de Bourgogne UmR 6303 Centre National de la Recherche Scientifique&Universitede Technologie de Belfort-MontbeliardUniversite Bourgogne Franche-ComteBelfort 90400France George W.Woodruff School of mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Laboratoire Reactions et Genie des Procedes UmR 7274 Centre National de la Recherche Scientifique-Universitede LorraineNancy 54001France

The integration of additive manufacturing(Am)in design and engineering has prompted a wide spectrum of research efforts,involving topologically optimized solid/lattice structures,multimaterial structures,bioinspired organic structures,and multiscale structures,to name a ***,except for obvious cases,very little attention has been given to the design and printing of more complex three-dimensional(3D)hollow structures or folded/creased *** of the main reasons is that such complex open or closed 3D cavities and regular/freeform folds generally lead to printing difficulties from support-structure-related *** address this barrier,this paper aims to investigate four-dimensional(4D)printing as well as origami-based design as an original research direction to design and build 3D support-free hollow *** work consists of describing the rough 3D hollow structures in terms of two-dimensional(2D)printed origami precursor layouts without any support *** origami-based definitions are then embodied with folding functions that can be actuated and fulfilled by 3D printed smart *** desired 3D shape is then built once an external stimulus is applied to the active materials,therefore ensuring the transformation of the 2D origami layout to 3D *** demonstrate the relevance of the proposal,some illustrative cases are introduced.

关键词： Origami-based design 4D printing Smart material hollow 3D structures Additive manufacturing

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