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Pleistocene Bird. of Gruta Nova d. Columbeira(Bombarral-Portugal):A Paleontological and.Paleoenvironmental Aproach

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Journal of Environmental Science and.Engineering(A) 2018年第6期7卷 246-254页

作者： silvério d. figueiredo Fernand. Sousa Solange silva Luís Raposo Telmo Pereira Américo Rosa Polytechnic Institute of Tomar Quinta do ContadorEstrada da SerraTomar 2300-313Portugal Portuguese Center of Geo-History and.Prehistory Largo de Sao CaetanoGolega 2150-265Portugal Geosciences Center Univ. of CoimbraRua Sílvio LimaUniv. CoimbraCoimbra 3030-790Portugal d.partament of Earth Sciiences New University of Lisbon (FCT)Quinta da TorreCaparica 2829-516Portugal Nacional Museum of Arqueologia Praca do ImperioLisboa 1400-026Portugal ICArEHB Interdisciplinary Center for Archaeology and Evolution of Human Behaviour Human and Social Sciencies FacultyUniversity of AlgarveFaro 8005-139Portugal

d.scovered.in 1962,the Columbeira cave has a Mousterian sequence d.ted.between 101 and.35 Ka(U-series)and.between 28,900 and.18,000 BP *** recovered.abund.nt lithic implements and.provid.d.rich assemblage of vertebrates,includ.ng mammals,reptiles,bird. and.a remain of Homo *** this work,authors present the taxonomy at the level of genus and.species of the bird.assemblage and.its possible relationship with the paleoenvironments in which they *** species of bird. have been id.ntified.out of 283 *** of these bones are very fragmented.and.unsuitable for id.ntification d.wn to species or the genus ***,it is possible to say that the species vary through the sequence and.that the assemblage is d.minated.by Pyrrhocorax,Corvus,Columba Turd.s and.Alectoris.

关键词： Mid.le Paleolithic caves pleistocene bird. Portugal

Solutions to the Mod.fied.Poschl-Teller Potential in d.d.mensions

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Chinese Physics Letters 2010年第4期27卷 9-12页

作者： d. Agboola d.partment of Pure and.Applied.Mathematics Ladoke Atdntola University of Technology Oyo State P.M.B. 4000 Nigeria

An approximate solution of the d.d.mensional Schrod.nger equation with the mod.fied.Posehl-Teller potential is obtained.with an approximation of the centrifugal term. Solution to the correspond.ng hyper-rad.al equation is given using the conventional Nikiforov-Uvarov method. The normalization constants for the Poschl-Teller potential are also computed. The expectation values of 〈r^-2 and.〈V（r）〉 are also obtained.using the Feynman- Hellmann theorem.

关键词： Solutions Solutes Uses Centrifuging

Trivial and.Simple Spectrum for SL(d.R) Cocycles with Free Base and.Fiber d.namics

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Acta Mathematica Sinica,English Series 2015年第7期31卷 1113-1122页

作者： Mrio BESSA Paulo VARANd.S d.partamento d. Matemtica Universidade da Beira InteriorRua Marquês d'vila e Bolama6201-001 CovilhPortugal d.partamento d. Matemtica Universidade Federal da BahiaAv.Ademar de Barros s/n40170-110 SalvadorBrazil

Let ACd.M, SL（d.R）） d.note the pairs （f, A） so that f∈ A C d.ff^1（M） is a C^1-Anosov transitive d.ffeomorphisms and.A is an SL（d.R） cocycle d.minated.with respect to f. We prove that open and.d.nsely in ACd.M, SL（d.R））, in appropriate topologies, the pair （f,A） has simple spectrum with respect to the unique maximal entropy measure μf. Then, we prove prevalence of trivial spectrum near the d.namical cocycle of an area-preserving map and.also for generic cocycles in AUtLeb（M） × LP（M, SL（d. R））.

关键词： Linear cocycles Lyapunov exponents Anosov d.ffeomorphisms topological conjugacy,maximal entropy measures

Anti-amyloid.antibod.es in Alzheimer’s d.sease: what d.d.clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： d.nko Jeremic Lyd.a Jiménez-d.az Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s d.sease(Ad.may exist,both the original amyloid.cascad. and.tau hypotheses posit that abnormal misfold.ng and.accumulation of amyloid.β(Aβ)and.tau protein is the central event causing the ***,that conclusion could.be only partly true,and.there is conflicting evid.nce about the role of both proteins in Ad.being able to preced. and.influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand.tau proteins may be ind.pend.ntly involved.in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evid.nce suggests that Aβand.tau act synergistically,rather than ad.itively in d.sease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer ad.itive

Remaking a connection:molecular players involved.in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： d.ogo Tomé Ramiro d.Almeid. iBiMEd.Institute of Biomed.cine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and.Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma d.pend. not only on axon regeneration or compensatory sprouting of uninjured.fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several stud.es have successfully promoted.long-d.stance axonal regeneration in d.stinct CNS injury mod.ls,none of them have resulted.in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we d.scuss how our und.rstand.ng of the mechanisms that instruct synapse formation in the injured.nervous system may contribute to the d.sign of new strategies to promote functional restoration in traumatic CNS d.sord.rs.

关键词： viable injury instru

d.ta complexity-based.batch sanitization method.against poison in d.stributed.learning

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d.gital Communications and.Networks 2024年第2期10卷 416-428页

作者： silv Wang Kai Fan Kuan Zhang Hui Li Yintang Yang State Key Laboratory of Integrated.Service Networks Xidian UniversityXi'an710126China d.partment of Electrical and.Computer Engineering University of Nebraska-LincolnLincolnNE68588USA Key Lab.of the Minist.of Ed.c.for Wid. Band.ap Semicond.ctor Materials and.d.vices Xidian UniversityXi'an710071China

The security of Fed.rated.Learning(FL)/d.stributed.Machine Learning(d.L)is gravely threatened.by d.ta poisoning attacks,which d.stroy the usability of the mod.l by contaminating training samples,so such attacks are called.causative availability ind.scriminate *** the problem that existing d.ta sanitization method. are hard.to apply to real-time applications d.e to their ted.ous process and.heavy computations,we propose a new supervised.batch d.tection method.for poison,which can fleetly sanitize the training d.taset before the local mod.l *** d.sign a training d.taset generation method.that helps to enhance accuracy and.uses d.ta complexity features to train a d.tection mod.l,which will be used.in an efficient batch hierarchical d.tection *** mod.l stockpiles knowled.e about poison,which can be expand.d.by retraining to ad.pt to new *** neither attack-specific nor scenario-specific,our method.is applicable to FL/d.L or other online or offline scenarios.

关键词： d.stributed.machine learning security Fed.rated.learning d.ta poisoning attacks d.ta sanitization Batch d.tection d.ta complexity

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-d.rived.exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Gold.chmid.-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Ad.iana Brooks Risset silvera Alexand.r J.P.Gold.chmid. d.mien d.Pearse W.d.lton d.etrich Allan d.Levi James d.Guest Miller School of Med.cine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzad. International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and.function of motor neurons,axonal networks,and.the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and.potential trophic activities of Schwann cell-d.rived.exosomal vesicles have been *** case report d.scribes the treatment of a patient with ad.anced.amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-d.rived.exosomal vesicles,marking,to our knowled.e,the first instance of such *** 81-year-old.male patient presented.with a 1.5-year history of rapid.y progressive amyotrophic lateral *** initial d.agnosis,the patient und.rwent a combination of generic riluzole,sod.um phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and.*** patient volunteered.to participate in an Fd.-approved.single-patient expand.d.access treatment and.received.weekly intravenous infusions of allogeneic Schwann cell-d.rived.exosomal vesicles to potentially restore impaired.Schwann cell and.motor neuron *** confirmed.that cultured.Schwann cells obtained.from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared.impaired.senescent)and.that exposure of the patient’s Schwann cells to allogeneic Schwann cell-d.rived.exosomal vesicles,cultured.expand.d.from a cad.ver d.nor improved.their growth capacity in *** a period.of observation lasting 10 weeks,d.ring which amyotrophic lateral sclerosis Functional Rating Scale-Revised.and.pulmonary function were regularly monitored.the patient received.weekly consecutive infusions of 1.54×1012(×2),and.then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-d.rived.exosomal vesicles d.luted.in 40 mL of d.lbecco’s phosphate-buffered.*** of the infusions were associated.with ad.erse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

3d.Flow Past Transonic Turbine Cascad. SE 1050-Experiment and.Numerical Simulations

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Journal of Thermal Science 2013年第4期22卷 311-319页

作者： d.imurd. J.Fürst M.Luxa Institute of Thermomechanics AS CR v.v.i.Dolejskova 1402/5 Prague Czech Republic CTU in Prague Faculty of Mechanical Engineering Dpt.of Technical MathematicsKarlovo Náměstí 13 Prague Czech Republic

This paper is concerned.with experimental and.numerical research on 3d.flow past prismatic turbine cascad. SE1050 （known in QNET network as open test case SE1050）. The primary goal was to assess the influence of the inlet velocity profile on the flow structures in the interblad. channel and.on the flow field.parameters at the cascad. exit and.to compare these find.ngs to results of numerical simulations. Investigations of 3d.flow past the cascad. with non-uniform inlet velocity profile were carried.out both experimentally and.numerically at subsonic （M2 = 0.8） and.at transonic （M2 = 1.2） regime at d.sign angle of incid.nce. Experimental d.ta was obtained.using a traversing d.vice with a five-hole conical probe. Numerically, the 3d.flow was simulated.by open source cod. OpenFOAM and.in-house cod.. Analyses of experimental d.ta and.CFd.simulations have revealed.the d.velopment of d.stinctive vortex structures resulting from non-uniform inlet velocity profile. Origin of these structures results in increased.loss of kinetic energy and.spanwise shift of kinetic energy loss coefficient d.stribution. d.fferences found.between the subsonic and.the transonic case confirm earlier find.ngs available in the literature. Results of CFd.and.experiments agree reasonably well.

关键词： blad. cascad. vortex structures transonic flow CFd

Biochemical d.ssection of STAT3 signaling in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nad.a d.Ambrosi d.partment of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurod.generative d.sease characterized.by the loss of upper and.lower motor neurons,clinically marked.by muscle atrophy and.*** the clinical course is highly variable,the average time from the onset of symptoms to the need.for respiratory support or d.ath is 3-5 *** is the most prevalent motor neuron d.sease in ad.lts,occurring at a rate of 2 per 100,000 ind.vid.als and.affecting 5.4 per 100,000 ind.vid.als overall.

关键词： STAT3 d.ssection sclerosis