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许丽治疗小儿先天性肌性斜颈失治经验介绍

新中医 2024年第8期56卷 208-212页

作者：林依玮陈思龙许丽(指导) 浙江中医药大学第三临床医学院浙江杭州310053 浙江中医药大学附属第三医院浙江杭州310005

介绍许丽教授治疗小儿先天性肌性斜颈失治的临床经验。许丽教授认为,本病作为先天胎产疾病,首先当问责于肾,随着患儿大动作发育,脾主四肢肌肉的作用在本病的发展转归中也越来越重要。故辨治原则主要为脾肾经同治,注重肌肉的养护。从现... 详细信息

介绍许丽教授治疗小儿先天性肌性斜颈失治的临床经验。许丽教授认为,本病作为先天胎产疾病,首先当问责于肾,随着患儿大动作发育,脾主四肢肌肉的作用在本病的发展转归中也越来越重要。故辨治原则主要为脾肾经同治,注重肌肉的养护。从现代解剖学上看,本病不应仅是局部胸锁乳突肌的问题,周围肌肉(肩背部、腰部、下肢部)也会出现代偿性变化,故辨治宜整体固护。在治疗对象上,不能局限于小儿,也应关注患儿家长的心理状态,减少家长在日常相处时传达给患儿的不良情绪,从而提高整体疗效。具体治法:补脾益肾法;揉捏牵转法;整体操作法;家庭调护法。

关键词：小儿先天性肌性斜颈失治高低肩脾肾同治推拿疗法许丽

许丽教授运用推拿治疗发育不良型肌性斜颈经验

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中医儿科杂志 2024年第2期20卷 26-29页

作者：陈思龙林依玮许丽(指导) 浙江中医药大学第三临床医学院浙江杭州310053 不详

许丽教授将因颈部肌肉发育欠佳、力量不足导致的小儿斜颈称为发育不良型肌性斜颈,临床治疗以推拿为主,效果显著。许教授认为,治疗发育不良型肌性斜颈应当从辨察左右气血、平衡颈部阴阳出发,既要注重局部肌肉力量的恢复,更要从整体上调... 详细信息

许丽教授将因颈部肌肉发育欠佳、力量不足导致的小儿斜颈称为发育不良型肌性斜颈,临床治疗以推拿为主,效果显著。许教授认为,治疗发育不良型肌性斜颈应当从辨察左右气血、平衡颈部阴阳出发,既要注重局部肌肉力量的恢复,更要从整体上调整筋骨,促进气血运行。局部治疗以揉、捏为主,辅以拿、弹拨、点按、拔伸、牵拉、旋转等手法;整体上注重颜面部、背部、下肢肌肉以及跟腱的放松,筋骨同治。此外,许教授十分注重家庭调护,强调“三分治疗,七分护理”,在推拿治疗的同时,也应安抚家长的焦虑,从而保证良好的疗效。附案例1则,以资验证。

关键词：发育不良型肌性斜颈小儿推拿临床经验许丽

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植物SWEET基因及其糖转运功能研究进展

河北科技大学学报 2024年第4期45卷 406-414页

作者：王鸿梅张召聪刘坤薛芳韩洁赵慧陈四龙河北科技大学食品与生物学院河北石家庄050018 河北科技大学图书馆河北石家庄050018

SWEET(sugars will eventually be exported transporter)是一类介导蔗糖或己糖通过顺浓度梯度被动扩散跨细胞膜转运的新型糖转运蛋白。植物SWEET蛋白包括7个跨膜结构域,其中包含2个MtN3/Saliva结构域,可分为4个进化分支。SWEET转运蛋... 详细信息

SWEET(sugars will eventually be exported transporter)是一类介导蔗糖或己糖通过顺浓度梯度被动扩散跨细胞膜转运的新型糖转运蛋白。植物SWEET蛋白包括7个跨膜结构域,其中包含2个MtN3/Saliva结构域,可分为4个进化分支。SWEET转运蛋白在多种生理和生化过程中发挥着关键作用,包括韧皮部装载、激素运输、营养和生殖生长等。结合当前SWEET转运蛋白的研究进展,重点总结了SWEET的发现、蛋白结构及其在糖转运中的生物学功能,指出目前植物SWEET基因研究面临的问题,并对未来SWEET蛋白的研究重点进行了展望:1)探究SWEET蛋白的底物识别机制;2)挖掘提高作物产量和品质的关键SWEET基因;3)利用SWEET基因编辑和磷酸化等策略改良作物产量和品质。

关键词：基因工程糖转运 SWEET 蛋白结构生物学功能

川芎嗪通过RAD52调控乳腺癌细胞DNA损伤修复

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现代肿瘤医学 2024年第1期32卷 47-52页

作者：黄溥婉陈思龙唐喜军伍湘峰李莉萍珠海市中西医结合医院检验科广东珠海519000 广东医科大学生化教研室广东东莞523808

目的:探究TMP对乳腺癌BT474细胞增殖、细胞周期及其调控蛋白表达与DNA双链断裂修复通路的相关性。方法:CCK8法测定TMP对乳腺癌BT474细胞的增殖抑制情况;流式细胞术测定TMP对细胞周期的影响;单细胞凝胶电泳测定分析TMP对损伤后细胞DSBs... 详细信息

目的:探究TMP对乳腺癌BT474细胞增殖、细胞周期及其调控蛋白表达与DNA双链断裂修复通路的相关性。方法:CCK8法测定TMP对乳腺癌BT474细胞的增殖抑制情况;流式细胞术测定TMP对细胞周期的影响;单细胞凝胶电泳测定分析TMP对损伤后细胞DSBs累积情况的影响;Isce-I内切酶系统检测TMP对修复通路活性的影响;Western blotting检测DSBs修复通路相关染色体结合蛋白表达水平变化。结果:TMP通过使细胞阻滞在G_(1)期呈浓度依赖性抑制BT474细胞增殖,显著减少体内由Zeocin导致的细胞拖尾DNA含量(P<0.05);TMP显著增加BT474细胞对RAD52、ERCC1、XRCC4以及DNA LigⅣ蛋白募集,减少对KU80蛋白募集,促进了SSA以及NHEJ通路修复活性(P<0.05)。结论:TMP通过阻滞BT474细胞停留在G_(1)期使其发挥增殖抑制作用的机制之一;TMP通过增强损伤缺口对各个通路的关键染色体结合蛋白募集,促进SSA与NHEJ修复通路活性从而减少DNA损伤。

关键词： DNA双链断裂修复川芎嗪乳腺癌细胞

Progress on genetic and genomic research for enhanced oil content and quality in peanut

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Oil Crop Science 2016年第1期1卷 1-8页

作者： Boshou LIAO Yong LEI Li HUANG silong chen Xiaoping REN Liying YAN Yurong LI Dongxin HUAI Xiaojing ZHOU Liyun WAN Yuning chen Wei HUA Huifang JIANG Oil Crops Research Institute of Chinese Academy of Agricultural Sciences Wuhan 430062 P. R. China Cereal and Oil Crops Research Institute of Hebei Academy of Agricultural and Forestry Sciences Shijiazhuang 050035 P. R. China

Peanut or groundnut (Arachis hypogaea L.) is an important source of vegetable oil in the world.Genetic enhancement for high yield and high oil content has greatly contributed to enhanced productivity of peanut and increased supply of peanut oil.Further improving oil content and quality of peanut is still crucial for increasing productivity of arable land and market competitiveness of peanut oil.Based on investigation among the peanut germplasm accessions including wild Arachis species,the oil content could be as high as 65％.Heterosis has been observed for oil content in hybrids derived from diverse crossing parents.Segregates with enhanced oil content have been obtained by pyramiding different genes or alleles with major and minor additive effects.Improved testing techniques for oil content in breeding lines with reduced cost have accelerated breeding progress for high oil content.SSR markers associated with oil content have been identified by association and linkage analysis.The stability of oil content in peanut across seasons and locations is highly associated with cold tolerance,high nutrition efficiency and drought tolerance.Recent progress on improving fatty acids in particular marker assisted backcrossing breeding has contributed to higher quality peanut oil and other products.High oil peanut lines with improved resistance to aflatoxin production have been developed.The wild Arachis species would be of great value for peanut breeding in increasing oil content.

关键词： Arachis hypogaea L. wild Arachis species oil content oleic acid fatty acid components resistance to aflatoxin production heterosis marker assisted breeding

Straw return influences the structure and functioning of arbuscular mycorrhizal fungal community in a rice-wheat rotation system

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Pedosphere 2024年第2期34卷 339-350页

作者： silong ZHAI Junjie XIE Zongyi TONG Bing YANG Weiping chen Roger TKOIDE Yali MENG Xiaomin HUANG Atta Mohi Ud DIN Changqing chen Haishui YANG College of Agriculture Nanjing Agricultural UniversityNanjing 210095China Department of Biology Brigham Young UniversityProvo UT 84602USA Jiangsu Key Laboratory of Crop Genetics and Physiology/Jiangsu Key Laboratory of Crop Cultivation and Physiology Agricultural College of Yangzhou UniversityYangzhou 225009China National Research Center of Intercropping The Islamia University of BahawalpurBahawalpur 63100Pakistan Jiangsu Collaborative Innovation Center for Modern Crop Production Nanjing Agricultural UniversityNanjing 210095China

Straw return is a sustainable soil fertility-building practice,which can affect soil microbial communities.However,how straw return affects arbuscular mycorrhizal fungi(AMF)is not well explored.Here,we studied the impacts of different straw management treatments over eight years on the structure and functioning of AMF communities in a rice-wheat rotation system.The straw management treatments included no tillage with no straw(NTNS),rotary tillage straw return(RTSR),and ditch-buried straw return(DBSR).The community structure of AMF was characterized using high-throughput sequencing,and the mycorrhizal functioning was quantified using an in situ mycorrhizal-suppression treatment.Different straw management treatments formed unique AMF community structure,which was closely related to changes in soil total organic carbon,available phosphorus,total nitrogen,ammonium,and nitrate.When compared with NTNS,RTSR significantly increased Shannon diversity in 0–10 cm soil layer,while DBSR increased it in 10–20 cm soil layer;DBSR significantly increased hyphal length density in the whole ploughing layer(0–20 cm),but RTSR only increased it in the subsurface soil layer(10–20 cm).The mycorrhizal responses of shoot biomass and nutrient(N and P)uptake were positive under both straw return treatments(RTSR and DBSR),but negative under NTNS.The community composition of AMF was significantly correlated to hyphal length density,and the latter was further a positive predictor for the mycorrhizal responses of plant growth and nutrient uptake.These findings suggest that straw return can affect AMF community structure and functioning,and farmers should manage mycorrhizas to strengthen their beneficial effects on crop production.

关键词： community structure hyphal length density shoot biomass shoot N uptake shoot P uptake soil physicochemical properties straw management tillage

Experimental design of paraffin/methylated melamine-formaldehyde microencapsulated composite phase change material and the application in battery thermal management system

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Journal of Materials Science & Technology 2024年第2期169卷 124-136页

作者： Que Huang silong Wang Jichun He Dengji Xu Safaa NAbdou Mohamed MIbrahim Shiqi Sun Yanjun chen Handong Li Ben Bin Xu Changcheng Liu Zeinhom M.El-Bahy Zhanhu Guo School of Environment and Safety Engineering North University of ChinaTaiyuan 030051China Institute of Advanced Energy Materials and Systems North University of ChinaTaiyuan 030051China School of Resources and Safety Engineering Central South UniversityChangsha 410010China School of Medical and BioInformation Engineering Northeastern UniversityShenyang 110819China Department of Chemistry Khurmah University CollegeTaif UniversityP.O.Box 11099Taif 21944Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 11099Taif 21944Saudi Arabia Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City 11884CairoEgypt

In order to maintain the optimal operating temperature of the battery surface and meet the demand for thermal storage technology,battery thermal management system based on phase change materials has attracted increasing interest.In this work,a kind of core-shell structured microcapsule was synthesized by an in-situ polymerization,where paraffin was used as the core,while methanol was applied to mod-ify the melamine-formaldehyde shell to reduce toxicity and improve thermal stability.Moreover,three different types of heat conductive fillers with the same content of 10 wt.%,i.e.,nano-Al_(2)O_(3),nano-ZnO and carbon nanotubes were added,generating composites.The microcapsules were uniform,and were not affected by the thermal fillers,which were evenly dispersed around.The composite sample with carbon nanotubes(10 wt.%)showed the highest thermal conductivity of 0.50 W/(m K)and latent heat of 139.64 J/g.Furthermore,according to the leakage testing and battery charge/discharge experiments,compared with Al_(2)O_(3)and ZnO,the addition of carbon nanotubes remarkably enhances the heat storage ability as latent heat from 126.98 J/g for the prepared sample with Al_(2)O_(3)and 125.86 J/g for the one with ZnO,then to 139.64 J/g,as well as dissipation performance as a cooling effect by decreasing the sur-face temperature of battery from 2%to 12%of microcapsule,composite sample with carbon nanotubes presents a broad application prospect in battery thermal management system and energy storage field.

关键词： Microcapsule Phase change material Battery Carbon nanotube Safety

环境影响后评价中的工作难点与解决措施——以南方某有色金属矿山采选项目为例

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皮革制作与环保科技 2022年第22期3卷 161-163页

作者：陈思龙中铝环保节能科技(湖南)有限公司长沙410014

以南方某有色金属矿山采选项目为案例,本文简述项目的工程特点和环境特征,分析矿山项目环境影响后评价应关注的重点工作内容,并结合评价过程中环境质量趋势分析中,可比对数据少且生态环境影响验证难以定量分析等工作难点,提出应用趋势... 详细信息

以南方某有色金属矿山采选项目为案例,本文简述项目的工程特点和环境特征,分析矿山项目环境影响后评价应关注的重点工作内容,并结合评价过程中环境质量趋势分析中,可比对数据少且生态环境影响验证难以定量分析等工作难点,提出应用趋势检验法和地理信息系统技术等相应的解决措施,以期对其它同类企业的环境影响后评价提供参考。

关键词：有色金属矿山环境影响后评价环境质量变化趋势

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《医师法》视域下我国多点执业法律问题研究

中国医院管理 2023年第3期43卷 67-69页

作者：李威张雪陈思龙王刚尹梅哈尔滨医科大学人文社会科学学院黑龙江哈尔滨150081 哈尔滨医科大学纪委办公室黑龙江哈尔滨150081 哈尔滨医科大学附属第四医院黑龙江哈尔滨150001

2022年3月1日起新施行的《医师法》明确规定了医师多点执业制度,为医师开展多点执业提供了法律保障。但不容忽视的客观现实是,《医师法》对医师多点执业的具体要求和风险分担未予以规定。有鉴于此,通过介绍我国《医师法》关于多点执业... 详细信息

2022年3月1日起新施行的《医师法》明确规定了医师多点执业制度,为医师开展多点执业提供了法律保障。但不容忽视的客观现实是,《医师法》对医师多点执业的具体要求和风险分担未予以规定。有鉴于此,通过介绍我国《医师法》关于多点执业内容的规定与现今医师多点执业的形式,借助司法实践成果,分析多点执业医师与多个医疗机构之间的法律关系以及在多点执业中容易出现的法律风险,进一步得出医师多点执业制度的完善措施及对策,进而保障医师多点执业的有序发展,促进和谐的医患关系。

关键词：《医师法》多点执业法律风险