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An Experimental Validation Study on Ferrofuid Evaporation

Chinese Journal of Mechanical Engineering 2022年第4期35卷 159-168页

作者： Wenjuan Yu Decai Li sifang niu School of Mechanical Electronic and Control Engineering Beijing Jiaotong UniversityBeijing 100044China State Key Laboratory of Tribology Tsinghua UniversityBeijing 100084China

The current research on the evaporation of ferrofuids mainly focuses on the characterization of ultra-low vapor pressure ferrofuids in vacuum and the theoretical analysis of the evaporation *** studies have focused on the experimental validation of the proposed evaporation rate equations and on the comparison of the diferences in ferrofuid *** this study,based on the Bolotov’s model,an evaporation rate equation is deduced from the experimental *** experimental study included a comparison of the evaporation,magnetic particle volume fraction,temperature,height of the fuid surface from the outlet,and magnetic feld of a kerosene-based ferrofuid and its base carrier *** prepared sample was evaporated in a test tube,and the evaporation rate was calculated by measuring the weight loss of the *** experimental results show that the evaporation rate of the base carrier liquid is higher than that of the *** smaller the volume fraction of the magnetic particles,the greater the evaporation *** magnetic particles play a key role in preventing evaporation of the base *** higher the temperature,the smaller the deviation of the evaporation rate from the predicted *** evaporation rates obtained by the two control groups at the height of the fuid surface from the outlet were lower than the predict *** magnetic feld had a certain promotional efect on the evaporation of the *** experimental results were consistent with the results obtained using Bolotov’s *** research validates Bolotov’s model and shows that the model is somewhat biased but still responds well to diferent variables.

关键词： Evaporation rate Experimental study Ferrofuid Kerosene Magnetic feld Validation

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不同预处理方法对污泥脱水性能的影响

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环境工程学报 2015年第8期9卷 4015-4020页

作者：苑宏英王亭祁丽牛四芳天津城建大学环境与市政工程学院天津300384 天津城建大学天津市水质科学与技术重点实验室天津300384

污泥脱水是污泥处理的关键步骤,本文以污泥比阻(SRF)为考察指标,对比分析了污泥经单独酸碱调节、酸碱联合调节、水浴加热、自然冻融以及氧化剂Fenton等预处理方法调节后污泥的脱水效果。结果表明,污泥经氧化剂Fenton试剂处理后,SRF明显... 详细信息

污泥脱水是污泥处理的关键步骤,本文以污泥比阻(SRF)为考察指标,对比分析了污泥经单独酸碱调节、酸碱联合调节、水浴加热、自然冻融以及氧化剂Fenton等预处理方法调节后污泥的脱水效果。结果表明,污泥经氧化剂Fenton试剂处理后,SRF明显减小,污泥脱水性能得到改善;先酸后碱调节的方式比单独酸、碱调节更利于污泥脱水;温度调节对污泥的比阻有影响,低温条件下污泥的比阻较小。

关键词：污泥比阻酸碱调节水浴加热自然冻融 Fenton试剂

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Applications of in-situ solid-state nuclear magnetic resonance in methanol to olefins reaction

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Science China Chemistry 2025年第1期68卷 134-151页

作者： Jing niu Shutao Xu Yingxu Wei Zhongmin Liu National Engineering Research Center of Lower-Carbon Catalysis Technology Dalian Institute of Chemical PhysicsChinese Academy of Sciences State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

The methanol-to-olefins（MTO） reaction offers an alternative pathway for the production of low-carbon olefins from non-oil feedstocks. Fundamental research has been impeded by a lack of comprehensive understanding of its underlying mechanism,despite the significant progress made in industry. In-situ solid-state nuclear magnetic resonance（ss NMR） spectroscopy has emerged as a pivotal tool, offering crucial insights into key species under real-time operando conditions. Furthermore, the host–guest interaction between zeolites or surface species residing on zeolites and the reactant/active intermediates is revealed by the combination of in-situ13C MAS NMR and 2D correlation spectroscopy. Moreover, recent technological advancements in hyperpolarization（HP） methods, including HP129Xe NMR and dynamic nuclear polarization（DNP）, have significantly improved the sensitivity of ss NMR, enabling detailed structural and kinetic analysis as well as the detection of trace species. In this feature article, we summarized recent advancements in（in-situ） ss NMR spectroscopy applied to MTO reaction processes,encompassing mechanistic investigations at various stages and the intricate host–guest interactions. These theoretical insights into the dynamic evolution of MTO reactions lay a solid foundation for the optimization of catalytic processes and the development of efficient catalysts, thereby advancing the techniques towards more sustainable and economical production route for olefins.

关键词： MTO zeolites in-situ ssNMR reactive intermediates reaction mechanism

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个性心理因素对三军官兵人性复杂性的影响

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中国健康心理学杂志 2014年第4期22卷 555-557页

作者：牛四芳娄振山第四军医大学航空航天医学系心理学教研室空军杭州航空医学鉴定训练中心训练部

目的探讨个性因素对三军官兵的影响模式,为其心理健康教育及心理咨询与治疗提供科学依据。方法采用人性的哲学修订量表中的复杂性分量表、卡特尔16种人格因素分析对路军、海军、空军3个军种总共1900名官兵进行心理测评。统计处理采用秩... 详细信息

目的探讨个性因素对三军官兵的影响模式,为其心理健康教育及心理咨询与治疗提供科学依据。方法采用人性的哲学修订量表中的复杂性分量表、卡特尔16种人格因素分析对路军、海军、空军3个军种总共1900名官兵进行心理测评。统计处理采用秩变换单因素方差分析、Spearman相关分析及Amos路径分析。结果不同文化程度的官兵在人性复杂性正性上有显著差异(F=2.87,P=0.04);Amos路径分析显示稳定性对新兵个性的贡献最大(β=0.75,P<0.01);个性对新兵人性复杂性正性的直接效应显著(β=0.27,P<0.001),其在部队属性与人性复杂性正性的存在显著的间接效应(β=0.04,P<0.01)。结论官兵对人性的复杂性的认识受个性影响最大,在个性因素影响下加强文化程度以及部队属性对官兵人性复杂性的认识,有必要针对官兵的个性因素进行专门的心理训练。

关键词：个性人性复杂性部队属性路径分析职业心理社会心理学

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Ubiquitin-specific protease 1 facilitates tumor immune escape from natural killer cells and predicts the prognosis in small cell lung cancer

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Oncology Research 2025年第1期33卷 213-224页

作者： SHIQIN JIANG YICHUN TANG FENG MA YUCHUN niu LEI SUN Department of Clinical Pharmacy Shenzhen Hospital of Integrated Traditional Chinese and Western MedicineShenzhen518104China Department of Pathology Zhujiang HospitalSouthern Medical UniversityGuangzhou510280China Department of Radiation Oncology The First People’s Hospital of FoshanFoshan528000China Department of Oncology The First Affiliated Hospital of Jinan UniversityJinan UniversityGuangzhou510630China Department of Oncology The First Dongguan Affiliated HospitalGuangdong Medical UniversityDongguan523721China

Objective:Small cell lung cancer(SCLC)is commonly recognized as the most fatal lung cancer *** substantial advances in immune checkpoint blockade therapies for treating solid cancers,their benefits are limited to a minority of patients with *** the present study,novel indicators for predicting the outcomes and molecular targets for SCLC treatment were ***:We conducted bioinformatics analysis to identify the key genes associated with tumor-infiltrating lymphocytes in *** functional role of the key gene identified in SCLC was determined both in vitro and in ***:A significant correlation was observed between patient survival and CD56dim natural killer(NK)cell ***,we noted that the hub gene ubiquitin-specific protease 1(USP1)is closely correlated with both CD56dim NK cells and overall survival in *** analysis revealed that USP1 is upregulated in *** addition,gene set enrichment analysis revealed that USP1 overexpression hinders NK cell-mediated immune *** co-cultivating NK-92 cells with SCLC cells,we demonstrated that NK cell cytotoxicity against SCLC could be improved either via USP1 knock-down or pharmacological ***,using a nude-mice xenograft tumor model,we noted that USP1 inhibition effectively suppressed tumor proliferation and increased the expression of NK cell-associated ***:Our study findings highlight the importance of NK cells in regulating ***1 overexpression can inhibit NK cell-mediated immunity;therefore,USP1 may serve not only as a prognostic biomarker but also as a potential molecular target of SCLC therapy.

关键词： Ubiquitin-specific protease 1(USP1) Natural killer(NK)cell Small cell lung cancer(SCLC) Prognosis Immune escape

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Weak KAM theory for two classes of almost periodic Hamiltonian systems

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Science China Mathematics 2025年

作者： Xun niu Kaizhi Wang Yong Li School of Mathematics and Statistics Center for Mathematics and Interdisciplinary SciencesNortheast Normal University School of Mathematical Sciences Shanghai Frontier Science Center of Modern Analysis (CMA-Shanghai)Shanghai Jiao Tong University Institute of Mathematics Jilin University

The purpose of this paper is to investigate the dynamics of Bohr almost periodic and Levitan almost periodic Hamiltonian systems via the weak KAM theory. We obtain minimal measures and weak KAM solutions in both cases. The weak KAM solution is a weak solution to the Hamilton-Jacobi equation, which formally transforms the original Hamiltonian systems into an integrable one. Consequently, we get the existence of an invariant torus in the aforementioned weak sense.

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C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2231-2244页

作者： Xiangzi Wang Xiaofei niu Yingkai Wang Yang Liu Cheng Yang Xuyi Chen Zhongquan Qi School of Medicine Guangxi UniversityNanningGuangxi Zhuang Autonomous RegionChina Graduate School of Tianjin University of Traditional Chinese Medicine TianjinChina Characteristic Medical Center of People’s Armed Police Forces TianjinChina Fujian Maternity and Child Health Hospital FuzhouFujian ProvinceChina

Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory *** expression of the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis exhibits significant differences before and after *** studies have revealed that the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis is closely associated with secondary inflammatory responses and the recruitment of immune cells following spinal cord injury,suggesting that this axis is a novel target and regulatory control point for *** review comprehensively examines the therapeutic strategies targeting the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis,along with the regenerative and repair mechanisms linking the axis to spinal cord ***,we summarize the upstream and downstream inflammatory signaling pathways associated with spinal cord injury and the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review primarily elaborates on therapeutic strategies that target the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the latest progress of research on antagonistic drugs,along with the approaches used to exploit new therapeutic targets within the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the development of targeted ***,there are presently no clinical studies relating to spinal cord injury that are focusing on the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review aims to provide new ideas and therapeutic strategies for the future treatment of spinal cord injury.

关键词： apoptosis C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway C-C motif chemokine receptor 2 antagonists chemokine ligand 2 chemokine receptor 2 inflammation macrophage microglia spinal cord injury therapeutic method

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Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

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Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu Xiang Renrui niu Xiaodong He Wenqi Luo Wanguo Liu Rui Gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

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Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

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Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

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反刍思维量表在不同性别和抑郁症状医学院校新生中的测量等值性

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心理与行为研究 2023年第6期21卷 854-860页

作者：李文福刘燕段熙明牛四方许瑞雪慕福芹济宁医学院精神卫生学院济宁272002 滨州医学院公共卫生与管理学院烟台264003 济宁医学院公共卫生学院济宁272002

采用10项目反刍思维量表(Ruminative Response Scale,RRS-10)和贝克抑郁量表对山东省两所医科院校8019名新生进行调查,使用多组验证性因素分析检验RRS-10在不同性别和抑郁症状医学院校新生中的测量等值性。结果发现,抑郁症状阳性组的RRS... 详细信息

采用10项目反刍思维量表(Ruminative Response Scale,RRS-10)和贝克抑郁量表对山东省两所医科院校8019名新生进行调查,使用多组验证性因素分析检验RRS-10在不同性别和抑郁症状医学院校新生中的测量等值性。结果发现,抑郁症状阳性组的RRS-10总分、强迫思考和反省深思因子分显著高于抑郁症状阴性组;RRS-10在男性和女性、抑郁症状阳性组和阴性组样本间的形态等值、弱等值、强等值和严格等值模型均成立。结果表明,RRS-10的二因子结构在不同性别以及抑郁症状医学院校新生间具有测量等值性。

关键词：反刍思维测量等值性性别差异抑郁症状医学院校新生

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