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China Communications 2024年第5期21卷 314-329页

作者： Wu Xiongyue tang Jianhua Marie siew Shien-Ming Wu School of Intelligent Engineering South China University of TechnologyGuangzhou 511442China Electrical and Computer Engineering Department Carnegie Mellon UniversityPittsburghPA 15213United States

The rapid development of emerging technologies,such as edge intelligence and digital twins,have added momentum towards the development of the Industrial Internet of Things(IIo T).However,the massive amount of data generated by the IIo T,coupled with heterogeneous computation capacity across IIo T devices,and users’data privacy concerns,have posed challenges towards achieving industrial edge intelligence(IEI).To achieve IEI,in this paper,we propose a semi-federated learning framework where a portion of the data with higher privacy is kept locally and a portion of the less private data can be potentially uploaded to the edge *** addition,we leverage digital twins to overcome the problem of computation capacity heterogeneity of IIo T devices through the mapping of physical *** formulate a synchronization latency minimization problem which jointly optimizes edge association and the proportion of uploaded nonprivate *** the joint problem is NP-hard and combinatorial and taking into account the reality of largescale device training,we develop a multi-agent hybrid action deep reinforcement learning(DRL)algorithm to find the optimal *** results show that our proposed DRL algorithm can reduce latency and have a better convergence performance for semi-federated learning compared to benchmark algorithms.

关键词： digital twin edge association industrial edge intelligence(IEI) semi-federated learning

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Spreadsheet quality assurance:a literature review

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Frontiers of Computer Science 2024年第2期18卷 61-82页

作者： Pak-Lok POON Man Fai LAU Yuen Tak YU Sau-fun tang School of Engineering and Technology Central Queensland UniversityMelbourne 3000Australia Department of Computing Technologies Swinburne University of TechnologyHawthorn 3122Australia Department of Computer Science City University of Hong KongHong Kong SAR 999077China The Royal Victorian Eye and Ear Hospital East Melbourne 3002Australia

Spreadsheets are very common for information processing to support decision making by both professional developers and non-technical end ***,business intelligence and artificial intelligence are increasingly popular in the industry nowadays,where spreadsheets have been used as,or integrated into,intelligent or expert systems in various application ***,it has been repeatedly reported that faults often exist in operational spreadsheets,which could severely compromise the quality of conclusions and decisions based on the *** a view to systematically examining this problem via survey of existing work,we have conducted a comprehensive literature review on the quality issues and related techniques of spreadsheets over a 35.5-year period(from January 1987 to June 2022)for target journals and a 10.5-year period(from January 2012 to June 2022)for target *** other findings,two major ones are:(a)Spreadsheet quality is best addressed throughout the whole spreadsheet life cycle,rather than just focusing on a few specific stages of the life cycle.(b)Relatively more studies focus on spreadsheet testing and debugging(related to fault detection and removal)when compared with spreadsheet specification,modeling,and design(related to development).As prevention is better than cure,more research should be performed on the early stages of the spreadsheet life *** by our comprehensive review,we have identified the major research gaps as well as highlighted key research directions for future work in the area.

关键词： decision support system end-user computing end-user programming Excel spreadsheet

Src inhibition rescues funDC1-mediated neuronal mitophagy in ischaemic stroke

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Stroke & Vascular Neurology 2024年第4期9卷 367-379,I0022-I0031页

作者： Tianchi tang Li-bin Hu Chao Ding Zhihua Zhang Ning Wang Tingting Wang Hang Zhou Siqi Xia Linfeng Fan Xiong-jie Fu Feng Yan Xiangnan Zhang Gao Chen Jianru Li Department of Neurosurgery Zhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 2NeurosurgeryZhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 3Zhejiang University School of MedicineHangzhouZhejiangChina 4Zhejiang University Department of PharmacologyHangzhouZhejiangChina

Background Ischaemic stroke triggers neuronal mitophagy,while the involvement of mitophagy receptors in ischaemia/reperfusion(I/R)injury-induced neuronal mitophagy remain not fully ***,we aimed to investigate the involvement of mitophagy receptor fun14 domain-containing 1(funDC1)and its modulation in neuronal mitophagy induced by I/R *** Wild-type and funDC1 knockout mice were generated to establish models of neuronal I/R injury,including transient middle cerebral artery occlusion(tMCAO)in vivo and oxygen glucose deprivation/reperfusion in *** outcomes of mice with two genotypes were *** mitophagy was analysed both in vivo and in *** of funDC1 and its regulator Src were *** impact of Src on funDC1-mediated mitophagy was assessed through administration of Src antagonist *** To our surprise,funDC1 knockout mice subjected to tMCAO showed stroke outcomes comparable to those of their wild-type *** neuronal mitophagy could be activated by I/R injury,funDC1 deletion did not disrupt neuronal *** activation of funDC1,represented by dephosphorylation of Tyr18,was detected in the early stages(within 3hours)of neuronal I/R injury;however,phosphorylated Tyr18 reappeared and even surpassed baseline levels in later stages(after 6hours),accompanied by a decrease in funDC1-light chain 3 *** inactivation of funDC1 was associated with Src activation,represented by phosphorylation of Tyr416,which changed in parallel with the level of phosphorylated funDC1(Tyr18)during neuronal I/R ***,funDC1-mediated mitophagy in neurons under I/R conditions can be rescued by pharmacological inhibition of *** funDC1 is inactivated by Src during the later stage(after 6hours)of neuronal I/R injury,and rescue of funDC1-mediated mitophagy may serve as a potential therapeutic strategy for treating ischaemic stroke.

关键词： funDC1 involvement injury

Effects of different drying methods on phenolic components and in vitro hypoglycemic activities of pulp extracts from two Chinese bayberry(Myrica rubra *** Zucc.)cultivars

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Food Science and Human Wellness 2022年第2期11卷 366-373页

作者： Zhe Liu Jiagan Zhang Shengmin Lu Weimin tang Yibin Zhou siew Young Quek Institute of Food Science Zhejiang Academy of Agricultural SciencesHangzhou 310021China School of Tea and Food Technology Anhui Agricultural UniversityHefei 230036China Food Science School of Chemical SciencesThe University of AucklandAuckland 1010New Zealand Riddet Institute Centre of Research Excellence for Food ResearchPalmerston North 4474New Zealand

The effects of two different drying methods,namely hot-air drying and freeze drying,on the phenolic profiles,antioxidant and hypoglycemic activities of pulp extracts from two main Chinese bayberry cultivars(’Biqi’or’BQ’and’Dongkui’or’DK’)were *** results showed that’BQ’bayberry provided higher total phenolic(TPC),total flavonoid(TFC)and total anthocyanin(TAC)contents than’DK’bayberry after the same drying method,while its antioxidant and hypoglycemic activities were highly affected by drying ***-dried samples possessed significantly higher TPC,TFC and TAC,and exhibited more potent antioxidant and hypoglycemic activities than hot-air dried ones(P<0.05).Freeze-dried’DK’bayberry exhibited similar antioxidant activities and a-amylase inhibitory activity,but higher a-glucosidase inhibition than freeze-dried’BQ’bayberry(P<0.05).Compared with hot-air dried samples,freeze-dried samples had significantly higher contents of cyanidin-3-O-glucoside,myricitin-3-O-rhamnoside,quercetin-3-O-galactoside,quercetin-3-O-glucoside and quercetin-3-O-rhamnoside,which had been proved to be the main contributors to the in vitro hypoglycemic activities of bayberry pulp *** these results demonstrate that freeze drying is more suitable for the preservation of phenolic components in the pulp extract of Chinese bayberry,and the pulp extract of freeze-dried’DK’could be applied as a potential hypoglycemic food additive.

关键词： Chinese bayberry Drying Phenolic components Antioxidant activities In vitro hypoglycemic activities

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半无限介质多自由度频响函数离散时间有理近似的稳定参数识别

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工程力学 2024年第8期41卷 1-10页

作者：李鑫唐贞云杜修力北京工业大学城市与工程安全减灾教育部重点试验室北京100124

离散时间有理近似函数是将半无限土频响函数转化为时域模型的重要工具,离散时间有理近似函数和时域模型具有相同的稳定性和精度。目前关于离散时间有理近似函数的研究只针对于单自由度系统。该文基于线性控制理论,给出了多自由度有理近... 详细信息

离散时间有理近似函数是将半无限土频响函数转化为时域模型的重要工具,离散时间有理近似函数和时域模型具有相同的稳定性和精度。目前关于离散时间有理近似函数的研究只针对于单自由度系统。该文基于线性控制理论,给出了多自由度有理近似系统的稳定条件。将稳定性条件与遗传-序列二次算法相结合,开发了多自由度频响函数参数辨识方法,保证了多自由度系统的稳定性和精度。不同维度的多自由度有理近似系统的数值仿真验证了该文方法可以保证多自由度有理近似系统的稳定性和精度。

关键词：离散时间有理近似函数多自由度参数识别稳定性精度

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Diamond-based electron emission:Structure,properties and mechanisms

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Chinese Physics B 2024年第9期33卷 165-177页

作者： Liang-Xue Gu Kai Yang Yan Teng Wei-Kang Zhao Geng-You Zhao Kang-Kang Fan Bo Feng Rong Zhang You-Dou Zheng Jian-Dong Ye Shun-Ming Zhu Kun tang Shu-Lin Gu School of Electronic Science and Engineering Nanjing UniversityNanjing 210046China

Diamond has an ultrawide bandgap with excellent physical properties,such as high critical electric field,excellent thermal conductivity,high carrier mobility,*** with a hydrogen-terminated(H-terminated)surface has a negative electron affinity(NEA)and can easily produce surface electrons from valence or trapped electrons via optical absorption,thermal heating energy or carrier transport in a PN *** NEA of the H-terminated surface enables surface electrons to emit with high efficiency into the vacuum without encountering additional barriers and promotes further development and application of diamond-based emitting *** article reviews the electron emission properties of H-terminated diamond surfaces exhibiting NEA *** electron emission is induced by different physical *** advancements in electron-emitting devices based on diamond are also ***,the current challenges and future development opportunities are discussed to further develop the relevant applications of diamond-based electronemitting devices.

关键词： diamond negative electron affinity (NEA) PN junction electron emission

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funDC1介导的线粒体自噬在肥胖性心肌病中信号通路的研究进展

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中国心血管杂志 2024年第5期29卷 475-480页

作者：唐嘉麟王一帆邓晓桦唐树耿郭中州谭迎南方医科大学第一临床医学院广州510515 南方医科大学珠江医院药学部广州510280 南方医科大学南方医院重症医学科广州510515

肥胖性心肌病是一种由肥胖导致的代谢性心脏病,其发生发展与线粒体自噬有关。线粒体自噬是一种重要的线粒体质控机制,而线粒体外膜蛋白含fun14域蛋白1(funDC1)在其中发挥着重要作用。本文就近年来funDC1介导的线粒体自噬在肥胖性心肌病... 详细信息

肥胖性心肌病是一种由肥胖导致的代谢性心脏病,其发生发展与线粒体自噬有关。线粒体自噬是一种重要的线粒体质控机制,而线粒体外膜蛋白含fun14域蛋白1(funDC1)在其中发挥着重要作用。本文就近年来funDC1介导的线粒体自噬在肥胖性心肌病发病机制中作用的研究进展作一综述,旨在为肥胖性心肌病的临床治疗提供新见解。

关键词：含fun14域蛋白1 线粒体自噬肥胖性心肌病信号通路

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基于Kano-FBS模型的智能桌面便签机设计

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工业设计 2024年第4期 87-90页

作者：韩康唐昌乔贵州大学美术学院贵阳550025

为帮助办公人群更高效率地完成工作并获得更多乐趣,同时缓解工作压力,将使用便利贴记事这一行为向智能化趋势靠拢,文章首先基于Kano模型深入分析智能桌面便签机用户需求,确定功能特性类型,并明确相对重要的用户体验需求。其次采用FBS模... 详细信息

为帮助办公人群更高效率地完成工作并获得更多乐趣,同时缓解工作压力,将使用便利贴记事这一行为向智能化趋势靠拢,文章首先基于Kano模型深入分析智能桌面便签机用户需求,确定功能特性类型,并明确相对重要的用户体验需求。其次采用FBS模型将关键需求与产品设计相对应,确保设计方案的合理性。最后通过理论模型的应用得到更具创新性和实用性的设计方案,提高用户工作效率的同时增添趣味性,为办公用品创新发展和改进提供有针对性的指导。

关键词：工业设计智能办公用品 Kano模型 FBS模型创新设计

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Prediction of overall survival following colorectal cancer surgery in elderly patients

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World Journal of Gastrointestinal Surgery 2019年第5期11卷 247-260页

作者： Isaac Seow-En Winson Jianhong Tan Sreemanee Raaj Dorajoo Sharon Hui Ling Soh Yi Chye Law Soo Yeun Park Gyu-Seok Choi Wah siew Tan Choong Leong tang Min Hoe Chew Department of Colorectal Surgery Singapore General HospitalSingapore 169608Singapore Department of General Surgery Sengkang General HospitalSingapore 544886Singapore Department of Pharmacy National University of SingaporeSingapore 117559Singapore Yong Loo Lin School of Medicine National University of SingaporeSingapore 117597Singapore Colorectal Cancer Center Kyungpook National University Chilgok HospitalKyungpook National University School of MedicineDaegu 702-210South Korea

BACKGROUND With advanced age and chronic illness,the life expectancy of a patient with colorectal cancer(CRC)becomes less dependent on the malignant disease and more on their pre-morbid *** major surgery for these elderly patients can be *** accurate tool demonstrating post-operative survival probability would be useful for surgeons and their *** To integrate clinically significant prognostic factors relevant to elective colorectal surgery in the elderly into a validated pre-operative scoring *** In this retrospective cohort study,patients aged 70 and above who underwent surgery for CRC at Singapore General Hospital between 1 January 2005 and 31 December 2012 were identified from a prospectively maintained *** with evidence of metastatic disease,and those who underwent emergency surgery or had surgery for benign colorectal conditions were excluded from the *** primary outcome was overall 3-year overall survival(OS)following surgery.A multivariate model predicting survival was derived and validated against an equivalent external surgical cohort from Kyungpook National University Chilgok Hospital,South *** analyses were performed using Stata/MP Version *** A total of 1267 patients were identified for *** median post-operative length of stay was 8[interquartile range(IQR)6-12]d and median follow-up duration was 47(IQR 19-75)*** OS was 78(IQR 65-85)*** multivariate analysis,the factors significant for predicting overall mortality were serum albumin<35 g/dL,serum carcinoembryonic antigen≥20μg/L,T stage 3 or 4,moderate tumor cell differentiation or worse,mucinous histology,rectal tumors,and pre-existing chronic obstructive lung *** age alone was not found to be *** Korean cohort consisted of 910 *** Singapore cohort exhibited a poorer OS,likely due to a higher proportion of advanced *** the clinicopathologic di

关键词： Colorectal cancer surgery Elderly Overall survival Pre-operative prognostic score