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Plant Diversity 2024年第1期46卷 39-48页

作者： Carlos A.vargas Marius Bottin Tiina Sarkinen James e.Richardson Marcela Celis Boris Villanueva Adriana Sanchez Programa de Biología Facultad de Ciencias NaturalesUniversidad del RosarioBogotaD.C.Colombia Subdireccion Científica Jardín Botanico de Bogota“Jose Celestino Mutis”BogotaD.C.Colombia Independent Researcher BogotaD.C.Colombia Tropical Diversity Section Royal Botanic Garden EdinburghUK School of Biological Earth and Environmental SciencesUniversity College CorkCorkIreland Departamento de Química y Biología Universidad del NorteKm.5 Vía Puerto ColombiaArea Metropolitana de Barranquilla 081007Colombia

Data gaps and biases are two important issues that af.e.t the quality of biodiversity information and downstream *** how best to fill existing gaps and account for biases is necessary to improve our current information most *** current main approaches for obtaining and improving data include(1)curation of biological collections,and(2)***,the comparative ef.e.tiveness of these approaches in improving biodiversity data remains little *** used the flora de Bogota project to study the magnitude of change in species richness,spatial coverage,and sample coverage of plant records based on curation versus *** process of curation resulted in a decrease in species richness(synonym and error removal),but it significantly increased the number of records per *** contributed to a slight increase in species richness,via accumulation of new ***,curation led to increases in spatial coverage,species observed by locality,the number of plant records by species,and localities by species compared to ***,curationwas more efficient in producing new information compared to f.e.dwork,mainly because of the large number of records available in *** recommend intensive curatorial work as the first step in increasing biodiversity data quality and quantity,to identify bias and gaps at the regional scale that can then be targeted with *** stepwise strategy would enable f.e.dwork to be planned more costef.e.tively given the limited resources for biodiversity exploration and characterization.

关键词： Colombia flora de Bogota Sample coverage Species richness Tropical Andes

exploring the size of Andean condor foraging groups along an altitudinal and latitudinal gradient in the Tropical Andes: ecological and conservation implications

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Current Zoology 2024年第2期70卷 225-232页

作者： Diego Mendez felix Hernan vargas JoséHernan Sarasola Pedro P.Oleaa Departamento de ecologia Universidad Autonoma de MadridCalle Darwin 228049MadridSpain Museo Nacional de Historia Natural Calle 26 s/nCota CotaLa PazBolivia The Peregrine fund 5668 West Flying Hawk LaneBoiseID 83709USA Centro para el estudio y Conservacion de Aves Rapaces en Argentina(CeCARA) Universidad Nacional de La PampaAvda Uruguay 1516300 Santa RosaLa PampaArgentina Instituto de las Ciencias Ambientales y de la Tierra de La Pampa(INCITAP-CONICeT) Avda.Uruguay 1516300 Santa RosaLa PampaArgentina Centro de Investigacion en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autonoma de MadridMadridCalle Darwin 228049Madrid Snain

Patterns of variation in the size of vulture foraging groups,and their ecological causes and consequences,remain litle explored despite strong links with the carrion recycling service that this key functional group *** documented the group size-f.e.uency pattern of Andean con-dors Vultur gryphus gathered to f.e. on 42 equine carcasses experimentally placed in Bolivia,between 2012 and 2019,along an elevation range of 1,300-4,500 m *** on the location(altitude and latitude)of the foraging groups,we examined the relationship between their size and species'population parameters(size and trend),habitat conditions,and livestock carcass availability and *** utilized a high f.e.uency(93%)of carcasses forming groups that ranged from 1 to 80 individuals(mean=25,median=18)and shaped a"lazy-J curve"typical pattern of size-f.e.uency distribution whereby few groups(5,12%)were large(>55 individuals)and most(21,50%)were relatively small(e related to altitude in that most larger groups formed at lower sites(below c.3,000 m asl),likely following an altitudinal gradient whereby larger groups are more likely to form around larger carcasses(i.e.,cattle),which are more likely to occur at lower *** of population size,group size could be an adaptive response of condors via local enhancement for improving individual scavenging *** information gaps on this topic still exist,thus we provide a set of questions to address them,especially amidst the unrestricted impacts of human activities that condition vulture survival globally.

关键词： condor andino fusion-fission dynamics group size scavenger social foraging vultures.

Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community:In search of shared genetic markers

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Genes & Diseases 2024年第4期11卷 106-108页

作者： Gloria Garavito-De egea Alex Dominguez-vargas Jorg e l.Velez Gustavo Aroca Luis fagng elkin Navarro-Quiroz Zilac espitaleta Kenny Del Toro-Camargo Leticia Martinez-Ariza Tatiana Gonzalez-vargas Susana Garcia Mauricio Arcos-Burgos eduardo egea Universidad del Norte Division Ciencias de la SaludBarranquillaColombia Universidad Simon Bolivar Facultad de Ciencias de la SaludBarranquillaColombia Clinica de la Costa Grupo de Investigacion en NefrologiaBarranquillaColombia Universidad de Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Genome-wide association studies(GWASs)have identif.e. hundreds of loci across the human genome conferring susceptibility to autoimmune diseases(AIDs),some of which are shared between more than two ***,this univariate ... 详细信息

关键词： susceptibility diseases diabetes

Assessing the impact of concurrent high-fructose and highsaturated fat diets on pediatric metabolic syndrome:A review

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World Journal of Clinical Pediatrics 2024年第2期13卷 62-79页

作者： Manuel Alejandro vargas-vargas Marcela González-Montoya Olin Torres-Isidro Claudia Isabel García-Berumen Omar Ortiz-Avila elizabeth Calderón-Cortés Christian Cortés-Rojo Instituto de Investigaciones Químico–Biológicas Universidad Michoacana de San Nicolás de HidalgoMorelia 58030MichoacánMexico facultad de enfermería Universidad Michoacana de San Nicolás de HidalgoMorelia 58020MichoacánMexico

High-saturated fat(Hf)or high-fructose(Hfr)consumption in children predispose them to metabolic syndrome(MetS).In rodent models of MetS,diets containing individually Hf or Hfr lead to a variable degree of ***,simultaneous intake of Hf plus Hfr have synergistic ef.e.ts,worsening MetS *** children,the ef.e.ts of Hf or Hfr intake usually have been addressed ***,we have reviewed the outcomes of Hf or Hfr diets in children,and we compare them with the ef.e.ts reported in *** humans,Hfr intake causes increased lipogenesis,hypertriglyceridemia,obesity and insulin *** the other hand,Hf diets promote low grade-inflammation,obesity,insulin *** the deleterious ef.e.ts of simultaneous Hf plus Hfr intake on MetS development in rodents,there is little information about the combined ef.e.ts of Hf plus Hfr intake in *** aim of this review is to warn about this issue,as individually addressing the ef.e.ts produced by Hf or Hfr may underestimate the severity of the outcomes of Western diet intake in the pediatric *** consider that this is an alarming issue that needs to be assessed,as the simultaneous intake of Hf plus Hfr is common on fast food menus.

关键词： fructose Saturated fat Metabolic syndrome Insulin resistance Type 2 diabetes Ultra processed foods Children Obesity Dyslipidemia Non-alcoholic fatty liver disease

Landscape of global urban environmental resistome and its association with local socioeconomic and medical status

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Science China(Life Sciences) 2024年第6期67卷 1292-1301页

作者： Jun Wu Yige Hu Michael H Perlin David Danko Jun Lu Manuela Oliveira Johannes Werner Maria M Zambrano Maria A sierra Olayinka O Osuolale Paweł Łabaj Nicolás Rascovan Nur Hazlin Hazrin-Chong Soojin Jang Haruo Suzuki Marina Nieto-Caballero Bharath Prithiviraj Patrick K H Lee Agnieszka Chmielarczyk Anna Różańska Yongxiang Zhao Lan Wang Christopher e Mason Tieliu Shi Center for Bioinformatics and Computational Biology and the Institute of Biomedical SciencesSchool of Life SciencesEast China Normal UniversityShanghai 200241China Department of Biology Program on Disease EvolutionUniversity of LouisvilleLouisville 40292USA Weill Cornell Medicine New York 10065USA The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine New York 10065USA Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200025China i3S-Instituto de Investiga玢o e Inova玢o em Saúde Universidade do PortoPorto 4050-290Portugal Ipatimup-Instituto de Patologia e Imunologia Molecular da Universidade do Porto Porto 4200-465Portugal Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPorto 4050-290Portugal High Performance and Cloud Computing Group Zentrum für Datenverarbeitung(ZDV)Eberhard Karls University of TübingenW鋍hterstra遝7672074TübingenGermany Corporación Corpogen Research Center Bogotá110311Colombia Applied environmental Metagenomics and Infectious Diseases Research(AeMIDR) Department of Biological SciencesElizade UniversityIlara-Mokin 340271Nigeria Maopolska Centre of Biotechnology Jagiellonian UniversityKraków 30-005Poland Aix-Marseille Université Mediterranean Institute of OceanologyUniversitéde ToulonCNRSIRDUM 110Marseille 83041France Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangor Institut Pasteur Korea Seoul 13488Republic of Korea faculty of.e.vironment and Information Studies Keio UniversityFujisawaKanagawa 252-0882Japan University of Colorado at Boulder CivilEnvironmental and Architectural DepartmentBoulder 80303USA Brooklyn College of the City University of New York Brooklyn 11210USA School of.e.ergy and environment City University of Hong KongHong Kong 999077China Department of Microbiology Faculty of MedicineJagiellonian UniversityKraków 30-005Poland Biological Targeting Diagnosis and The

Antimicrobial resistance(AMR)poses a critical threat to global health and development,with environmental factors—particularly in urban areas—contributing significantly to the spread of antibiotic resistance genes(ARGs).However,most research to date has been conducted at a local level,leaving significant gaps in our understanding of the global status of antibiotic resistance in urban *** address this issue,we thoroughly analyzed a total of 86,213 ARGs detected within 4,728 metagenome samples,which were collected by the Meta SUB International Consortium involving diverse urban environments in 60 cities of 27 countries,utilizing a deep-learning based *** findings demonstrated the strong geographical specificity of urban environmental resistome,and their correlation with various local socioeconomic and medical *** also identif.e. distinctive evolutionary patterns of ARG-related biosynthetic gene clusters(BGCs)across dif.e.ent countries,and discovered that the urban environment represents a rich source of novel *** study provides a comprehensive overview of the global urban environmental resistome,and fills a significant gap in our knowledge of large-scale urban antibiotic resistome analysis.

关键词： urban environment metagenome antibiotic resistance resistance diversity biosynthetic gene clusters

Dif.e.ential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

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Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo Diana Simón Johnny Di Pierdomenico Alejandro Gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier sierra Manuel Vidal-Sanz María Teresa Moreno-flores Marta Agudo-Barriuso Grupo de Investigación Oftalmología experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain experimental Sciences faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia af.e. optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TeG3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TeG3 express major histocompatibility complex classⅡ*** and syngenically transplanted TeG3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TeG3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than af.e. optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher af.e. allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** dif.e.ent neuroprotective properties,dif.e.ent toxic ef.e.ts,and dif.e.ent responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

New insights into the role of the endoplasmic reticulum in microglia

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Neural Regeneration Research 2024年第7期19卷 1397-1398页

作者： Veronika e.Neubrand M.Rosario Sepúlveda Department of Cell Biology Faculty of SciencesUniversity of GranadaGranadaSpain

Microglial cells are the only resident immune cells in the central nervous system and constitute its frontline *** are extremely reactive against infections,trauma,or toxins,but are also responsible for mediating inflammation,taking part in the pathogenic course of many neuropathologies(sierra et al.,2019).Cell-specific staining,ultrastructural analysis by transmission electron microscopy(TeM),or two-photonmicroscopy imaging have been relevant for the characterization of microglia as well as their cell-cell interactions。

关键词： inflammation reticulum

Artificial intelligence meets body sense: task-driven neural networks reveal computational principles of the proprioceptive pathway

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3147-3149页

作者： Leonard e.van Dyck frank Bremmer Katharina Dobs Department of Psychology Justus Liebig University GiessenGiessenGermany Max Planck Institute for Human Cognitive and Brain Sciences LeipzigGermany Center for Mind Brain and BehaviorUniversities of MarburgGiessenand DarmstadtMarburgGermany Department of Neurophysics Philipps-Universitat MarburgMarburgGermany

In a recent study published in Cell,Marin vargas and Bisi et al.1 present an innovative approach to unravel the computational principles underlying proprioceptive processing in non-human *** findings showcase the utility of task-driven modeling in advancing neuroscience and of.e. translational potential by providing seminal insights into the goals and mechanisms by which the brain encodes body position and movements.

关键词： networks neural principles

Acknowledgment of Libraries in the Journal Literature: An exploratory Study

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Journal of Data and Information Science 2020年第3期5卷 178-186页

作者： David e.Hubbard sierra Laddusaw Texas A&M University University LibrariesTAMU 5000 College StationTexas 77843USA

Purpose: This study examines acknowledgments to libraries in the journal literature, as well as the efficacy of using Web of Science(WoS) to locate general acknowledgment ***/methodology/approach: This mixed-methods approach quantif.e. and characterizes acknowledgments to libraries in the journal literature. Using WoS's funding Text f.e.d, the acknowledgments for six peer universities were identif.e. and then characterized. The efficacy of using WoS to locate library acknowledgments was assessed by comparing the WoS funding Text search results to the actual acknowledgment text found in the ***: Acknowledgments to libraries were found in articles at all six peer universities, though the absolute and relative numbers were quite low(f the library acknowledgments were for resources(collections, funding, etc.), and many were concentrated in natural history(e.g. zoology). examination of Texas A&M University zoology articles found that 91.7% of the funding information came from "acknowledgments" and not specifically a funding acknowledgment section. The WoS funding Text search found 56% of the library acknowledgments compared to a search of the actual acknowledgment text in the *** limitations: Limiting publications to journals, using a single truncated search term, and including only six research universities in the United *** implications: This study examined library acknowledgments, but the same approach could be applied to searches of other keywords, institutions/organizations, individuals, etc. While not specifically designed to search general acknowledgments, WoS's funding Text f.e.d can be used as an exploratory tool to search acknowledgments beyond funding. Originality/value: There are a few studies that have examined library acknowledgments in the scholarly literature, though to date none of those studies have examined the efficacy of using the WoS funding Text f.e.d to locate those library acknowledg

关键词： Acknowledgment Bibliometric analysis Libraries Web of Science