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中国有色冶金 1991年第1期 55-58页

作者： sidney A Hiscock ,黄奕清

镉经过1988年巨大而又振奋人心的变化后,1989年是一个平稳的年。但是,镉作为一种工业用的金属巳发生了很大的变化,它的地位得到加强。镉产量略有下降,但仍然是创记录的第二个高水平。精镉消耗量连续

关键词：消费量日本欧洲经济共同体生产量产量美元本位币电池工业库存量美国美利坚合众国北美洲

Fraud investigation in commercial coffee by chromatography

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Food Quality and Safety 2018年第3期2卷 121-133页

作者： Víctor de Carvalho Martins Ronoel Luiz de Oliveira Godoy Ana Cristina Miranda Senna Gouvêa Manuela Cristina Pessanha de Araujo Santiago Renata Galhardo Borguini Elaine Cristina de Oliveira Braga sidney Pacheco Luzimar da Silva de Mattos do Nascimento Departamento de Tecnologia de Alimentos Instituto de TecnologiaUniversidade Federal Rural do Rio de JaneiroCEP 23890-000Seropédica-RJBrazil Laboratório de Cromatografia Líquida Embrapa Agroindústria de AlimentosCEP 23020-470Rio de Janeiro-RJBrazil Centro de Tecnologia Instituto de QuímicaUniversidade Federal do Rio de JaneiroCEP 22290-180Rio de Janeiro-RJBrazil

Coffee is currently the second largest commodity on the world market today,and there is great concern about the quality of the beans exported from producer countries to Europe and *** such as using blends of different species and adding low-cost raw materials,such as chicory,corn,and soybean,impair the sensory and functional characteristics of the drink made from roasted and ground coffee *** is a need to adopt more efficient analytical methods than the microscopy technique currently *** first chromatographic method used to determine fraud was reported in *** method used paper chromatography to differentiate between coffee and chicory based on the free reducing *** of the 1980s,different methods involving high-performance liquid chromatography and gas chromatography were developed in order to demonstrate geographic authenticity,distinction between species,occurrence of adulteration,and the presence of defective beans by determining the monosaccharides,oligosaccharides,tocopherols,fatty acids,volatiles,diterpenes,sterols,and phenolic substances,among *** far as the authors know,there are no papers published in the literature that have compiled such an extensive set of information about these chromatographic methods as *** the last 2 years,there has been a trend to develop analytical methods for ultra-performance liquid chromatography coupled with tandem mass spectrometry to confirm fraud in coffee,due to high sensitivity and selectivity.

关键词： adulteration coffee chromatographic methods carbohydrates volatile substances

全尺寸深井钻井模拟装置对钻井技术发展的影响(英文)

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石油钻探技术 2011年第3期39卷 1-5页

作者：西德尼.格林斯伦贝谢创新中心犹他盐湖城84108 犹他大学工学院犹他盐湖城84108

缩短钻井周期是降低深井钻井成本和钻井风险的关键,这需要钻井新技术、新工艺、新材料、新工具的研究与应用,这必然要很大程度上依赖于大量的室内试验。斯伦贝谢Terra Tek钻完井实验室有全球最先进的全尺寸钻井模拟试验装置,在30多年间... 详细信息

缩短钻井周期是降低深井钻井成本和钻井风险的关键,这需要钻井新技术、新工艺、新材料、新工具的研究与应用,这必然要很大程度上依赖于大量的室内试验。斯伦贝谢Terra Tek钻完井实验室有全球最先进的全尺寸钻井模拟试验装置,在30多年间做了大量的模拟试验,试验结果对钻井技术发展、钻头设计、钻井液体系优选及性能优化起到了积极的促进作用。在介绍Terra Tek全尺寸钻井模拟试验装置的组成及主要功能的基础上,分析了该实验室在美国岩石力学协会钻井论坛、冲击钻井及深井钻井模拟试验中取得的主要成果,并介绍了该实验室在页岩气地层特点、开发技术和井眼稳定等方面取得的研究进展。

关键词：深井钻井钻井模拟页岩钻井

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炫动青春！

中国少年文摘 2009年第20期 48-48,F0003页

作者：暴暴蓝 sidney

2009年X Games亚洲极限运动锦标赛是中国上海第三次举办这一赛事。X Games亚洲极限运动锦标赛聚集了来自亚洲及世界上20多个国家的200多名优秀的极限运动员，进行BMX小轮车、极限直排轮滑、滑板和攀岩四大项目的比赛。

关键词：极限运动青春锦标赛亚洲运动员赛事轮滑比赛

2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI

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Science Bulletin 2019年第3期64卷 166-179页

作者： Yong Huo Young-Hoon Jeong Yanjun Gong Daowen Wang Ben He Jiyan Chen Guosheng Fu Yundai Chen Jianping Li Yi Li Shinya Goto Udaya S.Tantry Paul A.Gurbel Jong-Hwa Ahn Hyo-Soo Kim Myung Ho Jeong Yaling Han sidney C.Smith Jr. Junbo Ge Department of Cardiology Peking University First Hospital Department of Internal Medicine Gyeongsang National University School of Medicine and Cardiovascular Center Gyeongsang National University Changwon Hospital Division of Cardiology Internal Medicine Department Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Department of Cardiology Shanghai Chest Hospital affiliated to Shanghai Jiaotong University Department of Cardiology Guangdong General Hospital Department of Cardiology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Department of Cardiology Chinese PLAG General Hospital Department of Cardiology General Hospital of Northern Theater Command Department of Medicine (Cardiology) Tokai University School of Medicine Inova Center for Thrombosis Research and Drug Development Inova Heart and Vascular Institute Cardiovascular Center Department of Internal Medicine Seoul National University Hospital The Heart Research Center Nominated by Korea Ministry of Health and Welfare Chonnam National University Hospital Division of Cardiology University of North Carolina Department of Cardiology Fudan University Zhongshan Hospital

East Asians are the most populous race in the world and their health status is an important global *** with Caucasian populations, East Asian patients have a different benefit/risk ratio when using antithrombotic treatment. Despite this observation, treatment strategies in East Asian patients are mostly based on the American and European guidelines. Despite a lower platelet inhibitory response to clopidogrel, East Asian patients show a similar or even a lower rate of ischemic event occurrence and higher bleeding risk compared with Caucasian patients. For potent P2Y_(12) inhibitors(ticagrelor and prasugrel),East Asian patients have shown less favorable net clinical benefits compared with Caucasian patients,which may be related to differences in pharmacokinetic/pharmacodynamic profiles and therapeutic zone of antiplatelet effect. This updated consensus mainly focuses on state-of-the-art and current controversies in the East Asian population. In addition, when East Asian patients are administered potent P2Y_(12) receptor inhibitors, the strategies and ongoing trials to overcome the related hurdles are discussed.

关键词： East Asian Coronary artery disease Antiplatelet Bleeding

Method to assess component contribution to toxicity of complex mixtures： Assessment of puberty acquisition in rats exposed to disinfection byproducts

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Journal of Environmental Sciences 2017年第8期29卷 311-321页

作者： Shahid Parvez Glenn E.Rice Linda K.Teuschler Jane Ellen Simmons Thomas F.Speth Susan D.Richardson Richard J.Miltner E.sidney Hunter Ⅲ Jonathan G.Pressman Lillian F.Strader Gary R.Klinefelter Jerome M.Goldman Michael G.Narotsky Indiana University Richard M. Fairbanks School of Public Health Department of Environmental Health Sciences IUPUI Campus Indianapolis IN 46202 USA National Center for Environmental Assessment Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Lincla Teuschler and Associates St. Petersburg FL 33707 USA National Health and Environmental Effects Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Research Triangle Park NC 27711 USA National Risk Management Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Department of Chemistry and Biochemistry University of South Carolina Columbia SC 29208 USA

A method based on regression modeling was developed to discern the contribution of component chemicals to the toxicity of highly complex, environmentally realistic mixtures of disinfection byproducts（DBPs）. Chemical disinfection of drinking water forms DBP *** of concerns about possible reproductive and developmental toxicity, a whole mixture（WM） of DBPs produced by chlorination of a water concentrate was administered as drinking water to Sprague–Dawley（S–D） rats in a multigenerational study. Age of puberty acquisition,i.e., preputial separation（PPS） and vaginal opening（VO）, was examined in male and female offspring, respectively. When compared to controls, a slight, but statistically significant delay in puberty acquisition was observed in females but not in males. WM-induced differences in the age at puberty acquisition were compared to those reported in S–D rats administered either a defined mixture（DM） of nine regulated DBPs or individual DBPs. Regression models were developed using individual animal data on age at PPS or VO from the DM study. Puberty acquisition data reported in the WM and individual DBP studies were then compared with the DM models. The delay in puberty acquisition observed in the WM-treated female rats could not be distinguished from delays predicted by the DM regression model, suggesting that the nine regulated DBPs in the DM might account for much of the delay observed in the WM. This method is applicable to mixtures of other types of chemicals and other endpoints.

关键词： Drinking water disinfection byproducts DBP Puberty delay Four Lab Study Mixtures risk assessment

Perioperative glucose management and outcomes in liver transplant recipients: A qualitative systematic review

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World Journal of Transplantation 2018年第3期8卷 75-83页

作者： Prani Paka Sarah R Lieber Ruth-Ann Lee Chirag S Desai Robert E Dupuis Alfred sidney Barritt Division of Pharmacotherapy and Experimental Therapeutics UNC Eshelman School of Pharmacy University of North Carolina Division of Gastroenterology and Hepatology Department of Medicine University of North Carolina Division of Abdominal Transplant Department of Surgery University of North Carolina School of Medicine

AIM To investigate the relationship between post-liver transplantation(LT) glycemic control and LT outcomes. METHODS A qualitative systematic review on relevant prospective interventions designed to control glucose levels including insulin protocols. Studies investigating an association between glycemic control and post-LT outcomes such as mortality, graft rejection, and infection rate were reviewed. Pub Med, EMBASE, and other databases were searched through October 2016. RESULTS Three thousands, six hundreds and ninety-two patients from 14 studies were included. Higher mortality rate was seen when blood glucose(BG) ≥ 150 mg/dL(P = 0.05). BG ≥ 150 mg/dL also led to higher rates of infection. Higher rates of graft rejection were seen at BG > 200 mg/dL(P < 0.001). Mean BG ≥ 200 mg/dL was associated with more infections(P = 0.002).Nurse-initiated protocols and early screening strategies have shown a reduction in negative post-LT *** Hyperglycemia in the perioperative period is associated with poor post-LT outcomes. Only a few prospective studies have designed interventions aimed at managing post-LT hyperglycemia, post-transplant diabetes mellitus(PTDM) and their impact on post-LT outcomes.

关键词： Diabetes Liver transplant Non-alcoholic steatohepatitis Outcomes Non-alcoholic fatty liver disease

消泡剂和溶粘液剂作为术前用药改善胃镜观察效果

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消泡剂和溶粘液剂作为术前用药改善胃镜观察效果

作者：杰克斯（Jecson sidney De Carvalho Sanches）东南大学

学位级别：硕士

背景:上消化道内镜检查是诊断和治疗上消化道疾病最常用的方法之一,为鉴别早期肿瘤病变提供了独特的机会。为了获得最佳高质量的上消化道内镜,良好的胃和粘膜的可视化非常重要。然而,泡沫、气泡和黏液常常阻碍其可见性,此外,还延长了手... 详细信息

背景:上消化道内镜检查是诊断和治疗上消化道疾病最常用的方法之一,为鉴别早期肿瘤病变提供了独特的机会。为了获得最佳高质量的上消化道内镜,良好的胃和粘膜的可视化非常重要。然而,泡沫、气泡和黏液常常阻碍其可见性,此外,还延长了手术的持续时间,影响了患者的耐受性和执行内镜医师的满意度。目前内镜医师在内镜检查中使用不同的术前药物,以减少泡沫、气泡和黏液的含量。目的:评价不同术前用药的疗效及它们在上内镜检查中增强粘膜可视性和安全性的联合作用方法:单中心、前瞻性、双盲（患者和医生）、随机研究。共有250名患者转诊至东南大学附属中大医院,在消化科门诊和住院接受选择性胃镜检查。参与者被随机分配接受五种药物中的一种:A组:西甲硅油,B组:西甲硅油加链霉蛋白酶,C组:二甲硅油,D组:二甲硅油加链霉蛋白酶,E组:链霉蛋白酶。在内窥镜检查前15到30分钟,患者接受了指定组的术前准备。在内镜检查中,对食管、胃体和胃窦的粘膜可见度进行评估,可见度评分分为1-3分。1=无气泡和轻微气泡（≤25%气泡）),无黏液,粘膜清晰可见;2=中等气泡（25%0%气泡）黏液薄层,但不遮挡视力;3=严重气泡（≥50%气泡）黏液遮挡视力。符合以下排除标准的患者被排除在外:急诊病例,以前接受过全胃切除术的患者,胃肠道出血,已知肿瘤或狭窄,对试验药物过敏,孕妇或哺乳期妇女。结果:将250例患者、122例男性患者和128例女性患者随机分为5组,每组50例。5组在年龄、性别和主要手术指征方面均无统计学意义。在食管部位,C组和D组总得分最高。而在胃体和胃窦部位,B组和D组有着更好的视觉效果。结论:为了获得上消化道的最佳视野,使其不存在过多的气泡和黏液,建议在上消化道内镜检查前使用消泡剂（西甲硅油或二甲硅油）和溶黏液剂（链霉蛋白酶）。

关键词：上消化道内镜西甲硅油二甲硅油链霉蛋白酶内镜术前用药

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用离子渗氮改进挤压模具的性能

铝加工 1992年第1期15卷 29-33页

作者： sidney Dressler Eltro 刘宗尧

对于薄壁断面铝型材挤压模具,当液体和气体渗氮不能获得所需的表面性能时,离子渗氮可用来增加表面硬度和改善工作性能。所研制的渗氮设备能在异常辉光放电区自动控制,进行无局部过热的均匀热处理。辉光放电的实质是用必要的氮离子种类... 详细信息

对于薄壁断面铝型材挤压模具,当液体和气体渗氮不能获得所需的表面性能时,离子渗氮可用来增加表面硬度和改善工作性能。所研制的渗氮设备能在异常辉光放电区自动控制,进行无局部过热的均匀热处理。辉光放电的实质是用必要的氮离子种类保证模具表面获得均匀的覆盖层。模具表面的氮离子浓度和温度单独用一台专用微处理机控制。带有单独对流加热电源和等离子参数控制装置的热壁炉渗氮性能可靠,不需要专业水平较高的设备操作人员。

关键词：离子渗氮挤压模具异常辉光放电气体渗氮模具表面表面硬度加热电源局部过热渗氮温度覆盖层

Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

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World Journal of Gastroenterology 2017年第37期23卷 6854-6867页

作者： Diego Marques Layse Raynara Ferreira-Costa Lorenna Larissa Ferreira-Costa Romualdo da Silva Correa Aline Maciel Pinheiro Borges Fernanda Ribeiro Ito Carlos Cesar de Oliveira Ramos Raul Hernandes Bortolin André Ducati Luchessi Andrea Ribeiro-dos-Santos sidney Santos Vivian Nogueira Silbiger Laboratório de Bioanálise e Biotecnologia Molecular Universidade Federal do Rio Grande do Norte Programa de Pós-graduacao em Ciências Farmacêutica Universidade Federal do Rio Grande do Norte Laboratório de Genética Humana e Médica Universidade Federal do Pará Departamento de Cirurgia Oncológica Liga Norte Riograndense Contra o Cancer Laboratório de Patologia eCitopatologia Liga Norte Riograndense Contra o Cancer Depart-amento de Análises Clínicas e Toxicológicas Universidade Federal do Rio Grande do Norte Núcleo de Pesquisas em Oncologia Universidade Federal do Pará

AIM To investigate the association between 16 insertiondeletions(INDEL) polymorphisms, colorectal cancer(CRC) risk and clinical features in an admixed *** O n e h u n d re d a n d fo r ty p a t i e n t s w i t h C R C a n d 140 cancer-free subjects were examined. Genomic DNA was extracted from peripheral blood samples. Polymorphisms and genomic ancestry distribution were assayed by Multiplex-PCR reaction, separated by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and analyzed on Gene Mapper ID v3.2. Clinicopathological data were obtained by consulting the patients' clinical charts, intra-operative documentation, and pathology *** Logistic regression analysis showed that polymorphism variations in IL4 gene was associated with increased CRC risk, while TYMS and UCP2 genes were associated with decreased risk. Reference to anatomical localization of tumor Del allele of NFKB1 and CASP8 were associated with more colon related incidents than rectosigmoid. In relation to the INDEL association with tumor node metastasis(TNM) stage risk, the Ins alleles of ACE, HLAG and TP53(6 bp INDEL) were associated with higher TNM stage. Furthermore, regarding INDEL association with relapse risk, the Ins alleles of ACE, HLAG, and UGT1A1 were associated with early relapse risk, as well as the Del allele of TYMS. Regarding INDEL association with death risk before 10 years, the Ins allele of SGSM3 and UGT1A1 were associated with death *** The INDEL variations in ACE, UCP2, TYMS, IL4, NFKB1, CASP8, TP53, HLAG, UGT1A1, and SGSM3 were associated with CRC risk and clinical features in an admixed population. These data suggest that this cancer panel might be useful as a complementary tool for better clinical management, and more studies need to be conducted to confirm these findings.

关键词： Colorectal cancer Ins-del polymorphism Admixed population Potential biomarker Diagnostic Risk stratification Prognostic Clinical features