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Contribution of ARV Treatment in the Correction of Anemia in People Living with HIV during the First Semester in the Hematology Department of Conakry University Hospital

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World Journal of AIDS 2021年第4期11卷 143-151页

作者： Diakite Mamady Kante Ansoumane Sayon Keita Fatimata Ouendouno Soumana Camara Toumin Diallo Abdoul Goudoussy Kourouma Mamadou Sylla Mouctar Camara Fatou Awada Mohamed Traore Fodé Amara Magassouba Aboubacar Sidiki sidikiba sidibé Abdoulaye Touré Department of Hematology Conakry University Hospital Conakry Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Dermatology-MST Conakry University Hospital Conakry Guinea Department of Internal Medicine Conakry University Hospital Conakry Guinea Department of Infectious and Tropical Diseases Conakry University Hospital Conakry Guinea Public Health Department CHU Conakry Guinea

Introduction: Anemia is frequently associated with the natural course of people living with HIV (PLWHIV). The objective was to describe the evolution of anemia in PLWHIV during the first 6 months of ART and to identify the associated factors in the hematology service of the Ignace Deen national hospital of the Conakry University Hospital. Methods: This was a prospective, observational descriptive and analytical study lasting one year from August 1, 2019 to July 31, 2020. It focused on PLWHIV who were newly included in ART during the period of study in the Hematology Department of Ignace Deen Hospital. Results: Of 45 PLWHIV, 40 presented with anemia of 88.89%. The mean age was 40.16 years ± 12.29 years and extremes of 22 and 71 years. The female sex represented 65% of cases with a sex ratio of 0.54. Prolonged fever was the main reason for consultation, 97.5%. The HIV-1 serotype was represented in all anemic patients. At least one OI was found in 24 patients, 60%. MO anemia was severe (28.9%), moderate (44.4%) and mild (26.7%). At M6 it was moderate (5.9%) and light (94.1%). It was normochromic normocytic in 55%. At M0, statistical analysis was significant between anemia and OIs, WHO stage and CD4 count, but the link was not established at M6. Conclusion: Anemia is frequently associated with HIV infection linked to delayed treatment. Its development would be better with the establishment of good support. Specific actions should be taken to better identify the factors involved.

关键词： PLWHIV ART Treatment Anemia CHU Conakry

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Incidence of Primary Open-Angle Glaucoma at the Flamboyants Communal Medical Center of Conakry, Guinea

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Open Journal of Ophthalmology 2022年第3期12卷 233-241页

作者： Pierre Louis Lama Aly Sylla sidikiba Camara Céougna Sagno Oumar Raphiou Diallo Ibrahima Sory Souaré National Noncommunicable Diseases Programme Conakry Guinea FSTS Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Ophthalmology Regional Hospital of N’Zerekore Zerekore Guinea Department of Neurosurgery Sino Guinean Friendship Hospital Conakry Guinea

Background: Primary Open-Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin defined by alterations in the visual field, progressive loss of optic nerve fibers and ganglion cells, and an open iridocorneal angle in gonioscopy. It is the world’s leading cause of irreversible blindness. There is no epidemiological study in Guinea that allows us to locate the real level of the problem. The objective of this study is to determine the hospital incidence of POAG at the Centre Médical Communal (CMC) in the Flamboyants. Patients and Method: This was a descriptive cross-sectional study with a prospective collection for one year, from April 1, 2020 to March 31, 2021, in patients aged at least 40 years, received in consultation at the CMC in the Flamboyants. The diagnostic criterion for a new case of glaucoma was the presence in a patient of the following two signs: (excavation of the optical disc C/D ≥ 0.5 and alteration of the visual field) with an open angle at least stage 4 of the Shaffer and Etienne classification associated or not with ocular hypertonia and having never received anti glaucoma treatment. We described variables related to sociodemographic characteristics, visual acuity, intraocular pressures, papillary excavations, and visual field surveys. Informed consent from patients was sought and obtained. The confidentiality of the files was guaranteed. Results: 68 new cases of POAG were diagnosed out of 3220 consultations, an incidence rate of 2.11%. The average age was 58.2 years (10.64 with a male predominance of 63.23%. A family history of glaucoma was present in 11.36% of cases. Visual acuity was poor Conclusion: This study has shown us that POAG in our environment is relatively common, early onset, and rapidly evolving. The implementation of a rapid and reliable screening strategy by the Eye Health Program will make it possible to manage glaucoma from the earliest stages.

关键词： Primary Glaucoma Open-Angle Incidence Conakry Guinea

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Functional Results without Correction of Cataract Surgery during a Free Campaign at Siguiri Prefectural Hospital in Guinea

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Open Journal of Ophthalmology 2022年第3期12卷 259-268页

作者： Pierre Louis Lama Céougna Sagno Aly Sylla sidikiba Camara Balla Sovogui Niouma Alexis Ouendeno Oumar Raphiou Diallo National Eye Health Programme Conakry Guinea FSTS Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Ophthalmology Regional Hospital of N’Zerekore Zerekore Guinea

Background: Cataract is the leading cause of blindness in the world and its treatment is exclusively surgical. However, the results of cataract surgery are not always as good as is assumed and this aspect of surgical services needs a lot of attention. The purpose of this study is to evaluate the functional results of the free cataract surgery campaign carried out at the Siguiri Prefectural Hospital in Guinea. Patients and Method: This was a descriptive and retrospective cross-sectional study over a period of three months (1 October-31 December 2017). Records of cataract-operated patients during the study period were reviewed. The complete files for the main variables sought were retained. Sociodemographic data and visual acuity without pre- and post-operative correction were assessed. Functional outcomes were analysed according to WHO guidelines and recommendations for post-operative functional outcomes of cataract surgery. The data was collected and processed using Excel version 2010 software. Results: A total of 108 eyes from 102 patients were the subject of this present study on 314 eyes from 289 operated patients. 64 (%) men and 38 women (%) had a follow-up of 6 weeks after cataract surgery, a sex ratio of 1.68 in favor of women. The average age was 62.45 ± 15.20 years with extremes of 25 and 90 years. The age group from 60 to 69 years is the most represented with 46 cases or 45.45%. Housewives and farmers are the most represented strata with 42 cases (41.18%) and 31 cases (30.39%) respectively. The operative technique was Phaco A in 4/5 of the cases. No implant calculations were performed. Functional results indicate that 66% of patients had good visual acuity (≥3/10);29% of patients had borderline visual acuity (between 1/10 and 2/10) and 13.30% had poor visual acuity (Conclusion: The importance of the rate of poor results in our study should draw our attention to the conduct of free cataract surgery campaigns. The problem of cataract blindness is often compou

关键词： Cataract Surgery Functional Results Campaign Siguiri Guinea

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Pediatric Eye Trauma: Epidemiological, Clinical and Therapeutic Aspects at CADESSO in Donka, Guinea

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Open Journal of Ophthalmology 2022年第3期12卷 284-293页

作者： Pierre Louis Lama Céougna Sagno Ibrahima Fofana Aly Sylla sidikiba Camara Balla Sovogui Ismael Maomou Oumar Raphiou Diallo National Programme of Non-Communicable Diseases Conakry Guinea FSTS Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Ophthalmology Regional Hospital of N’Zerekore Zerekore Guinea Army Health Service Ministry of Defence Conakry Guinea Department of Ophthalmology Prefectoral Hospital of Macenta Macenta Guinea

Introduction: Eye trauma represents all morbid lesions on the eyeball due to external violence. In children, they are an important cause of morbidity and the leading cause of monocular blindness. The aim of this study was to determine the sociodemographic, clinical and therapeutic characteristics of eye trauma in children aged 0 to 16 at the Application Centre for the Diploma of Specialized Higher Studies in Ophthalmology (CADESSO) in Donka, Guinea. Patients and Method: This was a prospective longitudinal study with descriptive purposes from January 1 to December 31, 2019 involving 205 children victims of eye trauma. Variables related to sociodemographic, clinical and therapeutic characteristics were studied. Informed consent from patients and/or their parents was sought and obtained. The confidentiality of the files was guaranteed. The data entry was done on EPI-Info version 7 and the analysis using the Stata software. The tables were made in Excel 2010. Pearson’s Chi2 test was used for the comparison of proportions. Results: Pediatric eye trauma accounted for 9.31% of pediatric visits and 30.92% of all eye trauma cases. There was a male predominance with a sex ratio of 1.59. Age groups from 0 - 4 years;5 - 8 years and 9 - 12 were the most affected with 26.8%, 28.8% and 27.3% respectively and a decrease in the number of cases in the 13 - 16 age group (17.1%). Gambling and sports accidents accounted for 33.2%, followed by domestic accidents for 16.6% and physical injury for 8.2%. Eye contusion was the most represented at 66.3% followed by wounds of the globe 23.9% and burns at 5.9%. One hundred and twenty-six patients had received a determination of visual acuity (VA) at admission;99 were assessed at discharge and 27 were lost to follow-up. The VA ≥ 5/10th increased from 43.4% at admission to 79.8% after treatment. We had found 67% of vision ≥ 5/10 in eye bruises against 5% in eyeball wounds. Anti-inflammatories (99.5%)) were almost used. The sequelae wer

关键词： Eye Trauma Pediatric CADESSO

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