BACKGROUND Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac *** cardiac myxoma and other malignancies are extremely rare,and only limited cases have been *** SUMMARY We describe ...
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BACKGROUND Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac *** cardiac myxoma and other malignancies are extremely rare,and only limited cases have been *** SUMMARY We describe a young patient with newly diagnosed locally advanced laryngeal cancer,with a synchronous cardiac tumor detected on staging *** echocar-diogram showed the typical appearance of myxoma in the left *** cardiac surgery was performed in view of its obstructive features and post cardiac surgery recovery was *** patient was scheduled for subsequent oncological treatment for the laryngeal ***,due to rapid progression of the advanced laryngeal malignancy,he was placed on supportive *** To our knowledge,this is the first reported case of synchronous cardiac myxoma with laryngeal *** treatment strategy should be adopted to manage synchronous tumors in a multidisciplinary *** most life-threatening condition needs be treated *** resection,staged operations or simultaneous resection of both tumors have been reported with good outcomes.
It is of great significance to accurately and rapidly identify shale lithofacies in relation to the evaluation and prediction of sweet spots for shale oil and gas reservoirs. To address the problem of low resolution i...
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It is of great significance to accurately and rapidly identify shale lithofacies in relation to the evaluation and prediction of sweet spots for shale oil and gas reservoirs. To address the problem of low resolution in logging curves, this study establishes a grayscale-phase model based on high-resolution grayscale curves using clustering analysis algorithms for shale lithofacies identification, working with the Shahejie Formation, Bohai Bay Basin, China. The grayscale phase is defined as the sum of absolute grayscale and relative amplitude as well as their features. The absolute grayscale is the absolute magnitude of the gray values and is utilized for evaluating the material composition(mineral composition + total organic carbon) of shale, while the relative amplitude is the difference between adjacent gray values and is used to identify the shale structure type. The research results show that the grayscale phase model can identify shale lithofacies well, and the accuracy and applicability of this model were verified by the fitting relationship between absolute grayscale and shale mineral composition, as well as corresponding relationships between relative amplitudes and laminae development in shales. Four lithofacies are identified in the target layer of the study area: massive mixed shale, laminated mixed shale, massive calcareous shale and laminated calcareous shale. This method can not only effectively characterize the material composition of shale, but also numerically characterize the development degree of shale laminae, and solve the problem that difficult to identify millimeter-scale laminae based on logging curves, which can provide technical support for shale lithofacies identification, sweet spot evaluation and prediction of complex continental lacustrine basins.
Skins expose to kinds of risk factors for damage, such as the hormone drugs, skin care products and ultraviolet radiation, which is accompanied by the production of excessive reactive oxygen species(ROS)and eventually...
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Skins expose to kinds of risk factors for damage, such as the hormone drugs, skin care products and ultraviolet radiation, which is accompanied by the production of excessive reactive oxygen species(ROS)and eventually leads to hypertrichosis. This skin disease is not aesthetically pleasing and even causes psychological and spiritual problems such as inferiority, anxiety and irritability. Current therapies are limited and often unsatisfactory, such as pharmacological and physical therapies, which have adverse effects and cause the irreversible destruction of hair follicles. Gold nanoclusters have good biocompatibility and their biosynthesis in vivo is responsive to oxidative stress microenvironment(OSM), which could be a safe and effective drug for ROS-induced skin injury. In our study, we demonstrated that zero valence fluorescent gold nanoclusters(FGNCs) were in situ biosynthesized in the plucking-induced damaged skin but not in the normal skin after the administration of gold precursors(+3), while FGNCs inhibited hair follicle regeneration by negatively regulating nuclear transcription factor kappa B(NFκB)-mediated inflammatory response signaling pathway(NFκB/tumor necrosis factor-α(TNF-α) axis). This OSM-responsive in situ biosynthesis method is facile and safe and holds great promise for curing hypertrichosis associated with skin dermatitis and injury.
Polyhedral boranes are a class of well-known boron molecular clusters widely used in energy,chemistry,medicine,and materials science because of their unique physical and chemical *** efforts have been made in the past...
Polyhedral boranes are a class of well-known boron molecular clusters widely used in energy,chemistry,medicine,and materials science because of their unique physical and chemical *** efforts have been made in the past decades to find more effective synthetic methods for this important class of boron ***,existing synthetic methods suffer from low efficiency and low ***,we report a facile one-pot synthesis of[（CH3）3S]2B12H12with moderate yields at mild *** mechanisms for the multi-step chemoselective synthesis of B12H122-without other by-products are elucidated based on theoretical results and our previous *** Lewis base used in B–H bond condensation reaction,which acts as a hydrogen or to balance the newly generated polyhedral borane charges,is proposed and studied in *** current study has led to a more effective and selective synthetic method for B12H122-and has also implicated the syntheses of other new polyhedral boranes.
Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences ...
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Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon
Based on the high-resolution enhanced observation data of PM2.5 organic molecular tracers,aldehydes and ketone OVOC components,long-chain alkane IVOC components,and key species of atmospheric oxidation during Septembe...
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Positive matrix factorization （PMF） is one of the most widely used receptor models for PM2.5 source apportionment. The traditional PMF method generally uses inorganic （such as nitrate，sulfate，and EC） measurement...
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Positive matrix factorization （PMF） is one of the most widely used receptor models for PM2.5 source apportionment. The traditional PMF method generally uses inorganic （such as nitrate，sulfate，and EC） measurement data as input species to apportion PM2.5 sources. These species have ambiguous source origins;thus quantifying PM2.5 sources with high source sectors is difficult. In this study，online measurements of major chemical components，elemental tracers，as well as organic molecular markers were applied in a PMF model to investigate the differences between the major chemical components-based PMF （MCC） and organic molecular markers-based PMF （OMM） methods in terms of source identification，source separation，and source quantification. The results showed that with the input of organic molecular markers （such as polycyclic aromatic hydrocarbons，fatty acids，dicarboxylic acids，hydroxyl-dicarboxylic acids，C9 acids，and phthalic acid），the OMM method greatly enlarged the number of source factors identified. Further，industry emission，shipping emission，dust，vehicle emission，biomass burning，secondary nitrate，and secondary sulfate;two primary source factors （coal combustion and cooking emission）;and four secondary organic aerosol （SOA） source factors were also resolved in the OMM method. Comparing with the source profiles resolved by the MCC method，we found that OC/EC mass ratios in OMM-resolved source profiles of industry emission，vehicle emission，biomass burning，and coal combustion were closer to those obtained from emission inventories. In terms of source quantification，the mass contributions of vehicle emission and biomass burning resolved by the MCC method were notably higher than those resolved by the OMM method，especially under high O3 concentrations （> 120 μg·m-3）. This suggests that without the input of specific organic molecular markers，the MCC method was inclined to apportion parts of secondary source contributions into primary sources （such as vehicle emission and biomas
In Earth systems,thousands of terragrams(Tg)(1 Tg=10^(12) g)of mineral nanoparticles move around *** mineral nanoparticles have exhibited unexpected intrinsic enzyme-like characteristics(so called“mineral nanozymes”...
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In Earth systems,thousands of terragrams(Tg)(1 Tg=10^(12) g)of mineral nanoparticles move around *** mineral nanoparticles have exhibited unexpected intrinsic enzyme-like characteristics(so called“mineral nanozymes”),and are ubiquitously distributed in natural ecosystems such as the atmosphere,oceans,waters,and *** with natural enzymes,these mineral nanozymes have several advantages such as tunable catalytic efficiency and robustness to harsh conditions,e.g.,heat,acid,and alkaline *** mineral nanozymes are new products of multidisciplinary cross-cutting,they have been widely applied in various *** review,for the first time,systematically introduces the species and properties of mineral nanozymes in Earth systems,discusses the critical roles played by nanozymes in environmental biogeochemical cycles,compiles the interfacial processes and mechanisms of mineral nanozymes,and provides an overview of the future prospects of mineral nanozymes.
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