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single-cell profiling lights different cell trajectories in plants

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aBIOTECH 2021年第1期2卷 64-78页

作者： Hong-xiang Zheng Feng-hui Wu si-min li Xian Sheng Zhang Na Sui Shandong Provincial Key Laboratory of Plant Stress College of Life SciencesShandong Normal UniversityJi’nan 250014ShandongChina State Key Laboratory of Crop Biology College of Life SciencesShandong Agricultural UniversityTai’an 271018ShandongChina

The molecular mechanism of the maintenance and differentiation of plant stem cells is an eternal theme in studies on plant growth and *** advances in single-cell RNA sequencing(scRNAseq)methods have completely changed the understanding of cell heterogeneity and cell function,allowing research precision to identify the differentiation trajectory of stem cells maintained and differentiated at the cellular *** review aimed to mainly discuss the novel insights provided by scRNA-seq for the maintenance and initiation of plant stem cells,cell differentiation,cell response to environmental changes,and improvement strategies for *** addition,it highlighted additional perspectives beyond scRNA-seq,such as spatial transcriptomes,epigenomes,and single-cell multiomics,for a renewed understanding of stem cell maintenance and cell differentiation,thus providing potential targets and theoretical foundations for crop improvement.

关键词： Epigenomes Plant development Plant stem cells single-cell multi-omics single-cell RNA sequencing

Unveiling stability of multiple filamentation caused by axial symmetry breaking of polarization

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Photonics Research 2016年第5期4卷 29-34页

作者： si-min li Zhi-Cheng Ren ling-Jun Kong Sheng-Xia Qian Chenghou Tu Yongnan li Hui-Tian Wang MOE Key Laboratory of Weak light Nonlinear Photonics and School of Physics Nankai University National Laboratory of Solid State Microstructures and School of Physics Nanjing University Collaborative Innovation Center of Advanced Microstructures Nanjing University

Femtosecond laser filamentation is generally initialized from unpredictable symmetry breaking caused by random noise, causing it to be barely controlled. However, it is always anticipated for stable and controllable *** present and demonstrate the idea that hybridly polarized vector fields with axial symmetry broken polarization, associated with a pair of orthogonally linearly polarized vortices carrying the opposite-handed orbital angular momenta, could achieve controllable and robust multiple filamentation. Here, our motivation is to unveil the underlying physics behind such controllable and robust multiple filamentation. The symmetry breaking should first be actively controllable and then be able to effectively inhibit random noise. Robust multiple filamentation is inseparable from the fact that the phases between the multiple filaments are always locked. In contrast, uncontrollable multiple filamentation is always accompanied with loss of phase, i.e., the multiple filaments become incoherent to each other. Our results may offer a suggestion for achieving controllable and robust multiple filamentation in other systems.

关键词： AV HP

Synthesis and characterizations of boron and nitrogen co-doped high pressure and high temperature large single-crystal diamonds with increased mobility

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Chinese Physics B 2021年第6期30卷 625-630页

作者： Xin-Yuan Miao Hong-An Ma Zhuang-Fei Zhang liang-Chao Chen li-Juan Zhou min-si li Xiao-Peng Jia College of Physics Guangxi University of Science and TechnologyLiuzhou 545006China State Key Laboratory of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China Key Laboratory of Material Physics of ministry of Education and School of Physical EngineeringZhengzhou UniversityZhengzhou 450052China

We synthesized and investigated the boron-doped and boron/nitrogen co-doped large single-crystal diamonds grown under high pressure and high temperature(HPHT) conditions(5.9 GPa and 1290℃). The optical and electrical properties and surface characterization of the synthetic diamonds were observed and studied. Incorporation of nitrogen significantly changed the growth trace on surface of boron-containing diamonds. X-ray photoelectron spectroscopy(XPS) measurements showed good evident that nitrogen atoms successfully incorporate into the boron-rich diamond lattice and bond with carbon atoms. Raman spectra showed differences on the as-grown surfaces and interior between boron-doped and boron/nitrogen co-doped diamonds. Fourier transform infrared spectroscopy(FTIR) measurements indicated that the nitrogen incorporation significantly decreases the boron acceptor concentration in diamonds. Hall measurements at room temperature showed that the carriers concentration of the co-doped diamonds decreases, and the mobility increases obviously. The highest hole mobility of sample BNDD-1 reached 980 cm^(2)·V^(-1)·s^(-1), possible reasons were discussed in the paper.

关键词： high pressure and high temperature(HPHT) diamond growth of crystal boron and nitrogen codoped diamond

Electrophoretic Behavior of Spherical Polyelectrolyte Brushes

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华东理工大学学报（自然科学版） 2010年第2期36卷 238-238页

作者： ZHAO Kun WANG si-yi GAO min li li GUO Xu-hong State Key Laboratory of Chemical Engineering East China University of Science and Technology Shanghai 200237 China

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑life lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-min Qin Zhongliang li Wen‑Xia Su Jia‑min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous li deposition and highly reversible li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous li+flux lithium metal battery

Preparation and Characterization ofPerhydroxycucurbit[6]uril-Bonded silica Stationary Phasefor Hydrophilic-Interaction Chromatography

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Preparation and Characterization ofPerhydroxycucurbit[6]uril...

The Internet of Things under Federated Learning:A Review of the Latest Advances and Applications

中国化学会全国第十二届大环第四届超分子化学学术讨论会

作者： liu si-min Xu li Feng Yu-Qi Wu Cheng-Tai (Department of Chemistry Wuhan University Wuhan 430072)

＜正＞ For the first time, perhydroxylcucurbit[6]uril was grafted to silica gel as a hydrophilic-interaction chromatographic stationary phase. The retention mechanism of alkaloids on the stationary phase was discussed. The results indicate that the stationary phase behaves as a hydrophilic-interaction chromatographic packing. And several alkaloids were separated on the stationary phase.

关键词： Hydrophilic-interaction Perhydroxylcucurbituril Alkaloids

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Computers, Materials & Continua 2025年第1期82卷 1-39页

作者： Jinlong Wang Zhenyu liu Xingtao Yang min li Zhihan Lyu School of Information and Control Engineering Qingdao University of TechnologyQingdao260043China Anhui Province Key Laboratory of Intelligent Building&Building Energy Saving Anhui Jianzhu UniversityHefei230000China Department of Game Design Uppsala UniversityUppsala75310Sweden

With the rapid development of artificial intelligence,the Internet of Things(IoT)can deploy various machine learning algorithms for network and application *** the IoT environment,many sensors and devices generatemassive data,but data security and privacy protection have become a serious *** learning(FL)can achieve many intelligent IoT applications by training models on local devices and allowing AI training on distributed IoT devices without data *** review aims to deeply explore the combination of FL and the IoT,and analyze the application of federated learning in the IoT from the aspects of security and privacy *** this paper,we first describe the potential advantages of FL and the challenges faced by current IoT systems in the fields of network burden and privacy ***,we focus on exploring and analyzing the advantages of the combination of FL on the Internet,including privacy security,attack detection,efficient communication of the IoT,and enhanced learning *** also list various application scenarios of FL on the ***,we propose several open research challenges and possible solutions.

关键词： Federated learning Internet of Things sensors machine learning privacy security

Physarum polycephalum-inspired adaptive optimization design of artificial microtubular networks

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Science China Chemistry 2025年

作者： si-min Zeng Di-Wei Zheng Ting Pan Xing-Lan Ding Yun Zhang Chi-Hui Yang si-Xue Cheng Xian-Zheng Zhang Key Laboratory of Biomedical Polymers of ministry of Education&Department of Chemistry Wuhan University

Natural biological microtubular networks have undergone adaptive evolutionary selection and may offer viable solutions to design challenges in artificial microtubular networks. The plasmodium of the slime mold Physarum polycephalum(P. polycephalum) extends continuously to form a protoplasmic microtubular network structure, directly connecting food *** simulations revealed that the formation of this adaptive P. polycephalum microtubular network could be captured by a mathematical algorithm. Inspired by the P. polycephalum microtubular networks, we propose an adaptive optimization design method for artificial microtubular networks. Specifically, we utilized hydrogels with biodegradable and tissue-adhesive properties to replicate the P. polycephalum microtubular networks via photomask. In Rhodamine B diffusion and glucosecatalyzed reaction experiments, we found that the P. polycephalum microtubular networks exhibited significantly enhanced efficiency compared to vascular and artificial networks. Furthermore, we demonstrated the potential for uric acid(UA) degradation of the hydrogels with a real P. polycephalum microtubular network loaded with urate oxidase(UOx) in a rodent model of hyperuricemia. And this network achieved more than double the effect of the artificial network. This underscores the potential of natural microtubular networks to replace artificial microtubular networks.

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Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2982-2997页

作者： Hongli li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang min Yi Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina National Clinical Research Center for Metabolic Diseases ChangshaHunan ProvinceChina Hunan Academy of Chinese Medicine ChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina

Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut *** aim of this study was to investigate systemic changes that occur in Alzheimer’s disease,in particular the association between changes in peripheral organ metabolism,changes in gut microbial composition,and Alzheimer’s disease *** do this,we analyzed peripheral organ metabolism and the gut microbiota in amyloid precursor protein-presenilin 1(APP/PS1)transgenic and control mice at 3,6,9,and 12 months of ***-month-old APP/PS1 mice exhibited cognitive impairment,Alzheimer’s disease-related brain changes,distinctive metabolic disturbances in peripheral organs and fecal samples(as detected by untargeted metabolomics sequencing),and substantial changes in gut microbial composition compared with younger APP/PS1 ***,a strong correlation emerged between the gut microbiota and kidney metabolism in APP/PS1 *** findings suggest that alterations in peripheral organ metabolism and the gut microbiota are closely related to Alzheimer’s disease development,indicating potential new directions for therapeutic strategies.

关键词： Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis