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Comparison between Outcome of Myringoplasty with and without Ensuring the Patency of Aditus ad Antrum

International Journal of Otolaryngology and Head & Neck Surgery 2021年第4期10卷 268-276页

作者： Dillu Ram Kandel shyam thapa chhetri Sriti Manandhar Maya Metro Hospital Dhangadhi Nepal BPKIHS Dharan Nepal Birat Medical College Biratnagar Nepal

Background: Myringoplasty is a technique for the closure of the simple perforation of the tympanic membrane. For the better outcome, myringoplasty combined with cortical mastoidectomy has been tried in many studies. Objectives: To compare the outcome of repair of tympanic membrane perforations with myringoplasty alone versus myringoplasty with opening of blocked aditus if any by doing antrostomy. Methodology: This was a prospective study. Patients included in the study were randomly allocated into 2 groups, the group I and the group II. The group I included 17 patients undergoing myringoplasty with antrostomy and the group II included 17 patients undergoing only myringoplasty. The blocked aditus was made patent if it was found blocked during antrostomy procedure. Graft uptake rate and improvement in conductive hearing loss were measured as success rate. Results: Mean age of the patients in the group I was 23.12 ± 7.55 years. The mean age of patients in the group II was 25.53 ± 8.79 years. In the group I unilateral disease was present in 6 (35%) cases. In the group II unilateral disease was present in 12 (70.5%) cases. In the group I subtotal perforation was present in 9 (52.9%) cases and moderate to large perforation was present in 8 (47%) cases. In the group II subtotal perforation and moderate to large perforation were present in 9 (52.9%) and 8 (47%) cases respectively. Aditus was found to be blocked in eleven (64.7%) patients in the group I. Successful graft uptake was seen in twelve cases (70.58%) in the group I and eleven cases (64.7%) in the group II with all of them showing improvement in hearing. The success rate of the group I was 70.58% while success rate of the group II was 64.7%. The mean of pre-operative and post-operative air-bone gap was 31.94 ± 11.7 dB and 24.8 ± 10.55 dB respectively in the group I with the mean hearing gain of 7.06 ± 3.9 dB. Similarly, the mean of pre-operative an

关键词： Myringoplasty Antrostomy Cortical Mastoidectomy

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Comparison between Outcome of Myringoplasty with and without Ensuring the Patency of Aditus ad Antrum

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International Journal of Otolaryngology and Head & Neck Surgery（耳鼻喉） 2021年第4期

作者： Dillu Ram Kandel shyam thapa chhetri Sriti Manandhar

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Limited impacts of occasional tillage on dry aggregate size distribution and soil carbon and nitrogen fractions in semi-arid drylands

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International Soil and Water Conservation Research 2024年第1期12卷 96-106页

作者： Wooiklee S.Paye Vesh R.thapa Rajan Ghimire New Mexico State University Agricultural Science CenterClovisNM88101USA New Mexico State University Department of Plant and Environmental SciencesLas CrucesNM88003USA

Tillage management that minimizes the frequency and intensity of soil disturbance can increase soil carbon(C)and nitrogen(N)sequestration and improve the resilience of dryland cropping systems,yet the impact of occasional disturbance on soil aggregate formation and the soil organic carbon(SOC)storage within aggregates has not been studied *** evaluated the effect of four tillage management practices on soil dry aggregate size distribution,aggregate-protected C and N,mineral-associated organic matter carbon(MAOM-C),particulate organic matter carbon(POM-C),and corn(Zea mays L.)and sorghum(Sorghum bicolor(L.)Moench)yields in a semi-arid dryland cropping *** included conventional tillage(CT),strip-tillage(ST),no-tillage(NT),and occasional tillage(OT)management in a corn-sorghum *** macro-aggregates were 51-54%greater under ST,NT,and OT,while small and micro-aggregates were greater in *** tillage reduced soil aggregate-associated C by 28-31%in macro-aggregates and 47-53%in small aggregates at 26 months(M)sampling compared to ST,NT,and *** clay+silt fraction,CT had 14-16%,21-26%,and 36-43%less SOC at 7,14,and 26M samplings,respectively,than ST,NT,and *** associated N was generally similar under ST,NT,and OT,which was greater on average than *** MOAM-C and POM-C under ST,NT,and OT were generally greater than respective SOC fractions under CT at 19 and 26 M after OT *** and sorghum yields were similar among tillage systems in 2020,but greater under ST,NT,and OT than CT in *** results suggest that while frequent intensive tillage can lower SOC and N storage,a single stubble mulch occasional tillage after several years of NT does not lead to soil C and N losses and soil structural instability in semi-arid drylands.

关键词： Conventional tillage Occasional tillage Aggregate associated carbon Mineral associated organic matter carbon(MAOM-C) Particulate organic matter carbon(POM-C)

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Anisotropic quintessence compact star in f(T)gravity with Tolman–Kuchowicz metric potentials

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Communications in Theoretical Physics 2024年第1期76卷 61-75页

作者： Piyali Bhar Farook Rahaman shyam Das Somi Aktar Abdelghani Errehymy Department of Mathematics Government General Degree College SingurHooghlyWest Bengal 712409India Department of Mathematics Jadavpur UniversityKolkata 700032West BengalIndia Department of Physics Malda College MaldaWest Bengal 732101India Astrophysics Research Centre School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa

To obtain analytically relativistic quintessence anisotropic spherical solutions in the f(T)paradigm is the primary objective of this *** do this,the pressure anisotropy condition is imposed,and we employ a metric potential of the Tolman–Kuchowicz(TK)*** also suppose that our current model incorporates a quintessence field characterized by a parameterωq,in addition to the anisotropic matter *** the presence of the parameterα,the field equations are modified by the choice of the f(T)*** f(T)gravity parameterαadds new components to the basic physical characteristics,such as density,pressure,subliminal sound velocity,surface redshift,etc,of the present *** selecting the compact star Her X-1 and varyingαfrom 0.5 to 2.5,we examined all the physical characteristics of the model parameter of the *** graphical process demonstrates that a more compact item is produced with greater values ofα.The hydrostatic equilibrium condition of the model is discussed,as well as the mass-radius relationship for our current model is obtained.

关键词： quintessence star f(T)gravity stability condition

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Multifunctional nanoparticle-mediated combining therapy for human diseases

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Signal Transduction and Targeted Therapy 2024年第2期9卷 343-375页

作者： Xiaotong Li Xiuju Peng Makhloufi Zoulikha George Frimpong Boafo Kosheli thapa Magar Yanmin Ju Wei He School of Pharmacy China Pharmaceutical UniversityNanjing 2111198PR China Xiangya School of Pharmaceutical Sciences Central South UniversityChangsha 410013PR China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Combining existing drug therapy is essential in developing new therapeutic agents in disease prevention and *** preclinical investigations,combined effect of certain known drugs has been well established in treating extensive human *** to synergistic effects by targeting various disease pathways and advantages,such as reduced administration dose,decreased toxicity,and alleviated drug resistance,combinatorial treatment is now being pursued by delivering therapeutic agents to combat major clinical illnesses,such as cancer,atherosclerosis,pulmonary hypertension,myocarditis,rheumatoid arthritis,inflammatory bowel disease,metabolic disorders and neurodegenerative *** therapy involves combining or co-delivering two or more drugs for treating a specific ***(NP)-mediated drug delivery systems,i.e.,liposomal NPs,polymeric NPs and nanocrystals,are of great interest in combinatorial therapy for a wide range of disorders due to targeted drug delivery,extended drug release,and higher drug stability to avoid rapid clearance at infected *** review summarizes various targets of diseases,preclinical or clinically approved drug combinations and the development of multifunctional NPs for combining therapy and emphasizes combinatorial therapeutic strategies based on drug delivery for treating severe clinical ***,we discuss the challenging of developing NP-codelivery and translation and provide potential approaches to address the *** review offers a comprehensive overview for recent cutting-edge and challenging in developing NP-mediated combination therapy for human diseases.

关键词： drugs diseases prevention

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Oxygen functionalization-assisted anionic exchange toward unique construction of flower-like transition metal chalcogenide embedded carbon fabric for ultra-long life flexible energy storage and conversion

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Carbon Energy 2024年第1期6卷 72-93页

作者： Roshan M.Bhattarai Kisan chhetri Nghia Le Debendra Acharya Shirjana Saud Mai Cao Hoang Phuong Lan Nguyen Sang Jae Kim Young Sun Mok Department of Chemical Engineering Jeju National UniversityJejuRepublic of Korea Department of Nano Convergence Engineering Jeonbuk National UniversityJeonjuRepublic of Korea Regional Leading Research Center(RLRC)for Nanocarbon-based Energy Materials and Application Technology Jeonbuk National UniversityJeonjuRepublic of Korea Department of Chemistry Mississippi State UniversityStarkvilleMississippiUSA Nanomaterials and System Laboratory Department of Mechatronics EngineeringJeju National UniversityJejuRepublic of Korea

The metal-organic framework(MOF)derived Ni–Co–C–N composite alloys(NiCCZ)were“embedded”inside the carbon cloth(CC)strands as opposed to the popular idea of growing them upward to realize ultrastable energy storage and conversion *** NiCCZ was then oxygen functionalized,facilitating the next step of stoichiometric sulfur anion diffusion during hydrothermal sulfurization,generating a flower-like metal hydroxysulfide structure(NiCCZOS)with strong partial implantation inside *** obtained NiCCZOS shows an excellent capacity when tested as a supercapacitor electrode in a three-electrode ***,when paired with the biomass-derived nitrogen-rich activated carbon,the asymmetric supercapacitor device shows almost 100%capacity retention even after 45,000 charge–discharge cycles with remarkable energy density(59.4 Wh kg^(-1)/263.8μWh cm^(–2))owing to a uniquely designed ***,the same electrode performed as an excellent bifunctional water-splitting electrocatalyst with an overpotential of 271 mV for oxygen evolution reaction(OER)and 168.4 mV for hydrogen evolution reaction(HER)at 10 mA cm−2 current density along with 30 h of unhinged chronopotentiometric stability performance for both HER and ***,a unique metal chalcogenide composite electrode/substrate configuration has been proposed as a highly stable electrode material for flexible energy storage and conversion applications.

关键词： carbon cloth energy conversion energy storage flexible metal embedding ultra-stable

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应用改进的Morgan-Morgan-Finney模型评估土壤侵蚀易感性:以尼泊尔Kulekhani流域为例

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Journal of Resources and Ecology 2024年第1期15卷 182-196页

作者： thapa Rabin JOSHI Rajeev BHATTA Binod GHIMIRE Santosh 尼泊尔赫陀达农林大学林业学院尼泊尔Hetauda44107 尼泊尔乌达布尔农林大学自然资源管理学院尼泊尔UdayapurKatari56310

本研究旨在考察Kulekhani流域土地利用与土地覆盖(LULC)动态变化及土壤侵蚀情况,并对2000年至2020年不同LULC类别进行分析。研究结果显示,Kulekhani流域森林土地比例从2000年的60.72%上升至2010年的62.43%,2020年达到64.75%。水域面积... 详细信息

本研究旨在考察Kulekhani流域土地利用与土地覆盖(LULC)动态变化及土壤侵蚀情况,并对2000年至2020年不同LULC类别进行分析。研究结果显示,Kulekhani流域森林土地比例从2000年的60.72%上升至2010年的62.43%,2020年达到64.75%。水域面积有小幅增加,2000年占比为1.07%,2020年增加到1.08%。相应地,荒地面积从0.21%增至0.35%。相反,农业用地比例逐渐减少,2000年为38%,2010年为36.24%,2020年降至33.82%。使用改进的Morgan-Morgan-Finney模型估算土壤流失量显示,2000年到2010年期间,加权平均土壤流失量呈下降趋势,而2010年到2020年期间略微增加。计算得出的土壤流失值分别为2000年8.64 t ha^(-1)yr^(-1)、2010年7.12 t ha^(-1)yr^(-1)和2020年7.30 t ha^(-1)yr^(-1)。土壤侵蚀易感性图表明,2000年到2020年期间,非常低风险的土壤侵蚀区域有所增加,主要集中在森林地区,而农业区域则显示出低到中度的易感性。此外,荒地区域显示出中高度的土壤侵蚀易感性。为解决这些问题,建议未来的努力应包括在荒地地区进行造林计划,在农业区域实施保护耕作方式,并采取适当的道路稳定措施。

关键词：水泥沙土地利用土地覆盖坡度降雨量

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亚洲凤凰属物种：研究趋势、状态、分布、民族植物学和药理活性（英文）

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Journal of Resources and Ecology 2024年第5期15卷 1382-1392页

作者： Santosh AYER Amrita BHUSAL Pratima chhetri Anuska SUBEDI 卡塔里农业与林业大学自然资源管理学院

凤凰属物种因其深远的生态、经济和文化意义而闻名,已在亚洲范围内引起了广泛关注。然而,在该地区对凤凰属物种的研究趋势、状态、分布、民族植物学和药理活性的研究仍然有限。本研究旨在为亚洲凤凰属物种收集相关信息。我们采用了系统... 详细信息

凤凰属物种因其深远的生态、经济和文化意义而闻名,已在亚洲范围内引起了广泛关注。然而,在该地区对凤凰属物种的研究趋势、状态、分布、民族植物学和药理活性的研究仍然有限。本研究旨在为亚洲凤凰属物种收集相关信息。我们采用了系统综述和荟萃分析的首选报告项目（PRISMA）方法,系统地审查了亚洲地区有关凤凰属物种的文献,分析了从2000年到2023年的亚洲凤凰属物种的研究趋势。结果共发现了42项相关研究,时间分布表明,多年来对凤凰属物种的关注度波动较大,显示出持续增长的研究兴趣, 2019年发表的文章数量达到了显著高峰。从地理分布上,研究的集中区域仅限于亚洲48个国家中的12个,鉴于凤凰属物种的广泛分布,因此需要进行更广泛的探索。目前研究的主题主要集中在药理学,其次是民族植物学、形态学、分类学、材料科学、环境工程和生态学。值得注意的是,研究不成比例地集中在Phoenix dactylifera属物种上,较少涉及其他物种。对研究重点、物种分布和地理代表性的分析强调了多样化研究主题的重要性,探索亚洲各地较少研究的凤凰属物种的生态、经济和文化意义,以揭示其在亚洲景观中的全部潜力和重要性。

关键词：凤凰属物种研究趋势民族植物学多功能植物亚洲

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Optimization of pelleting parameters for producing composite pellets using agricultural and agro-processing wastes by Taguchi-Grey relational analysis

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Carbon Resources Conversion 2020年第1期3卷 104-111页

作者： shyam thapa Robert Engelken Natural Sciences Aims Community CollegeGreeleyCO 80634USA College of Agriculture Engineering and TechnologyArkansas State UniversityState UniversityJonesboroAR 72467USA

Agricultural and agro-processing sector produces large stream of by-products that are either discarded or are *** biomass especially crop residues’potential to green energy development has been *** conditions as process variable was made a centerpiece of investigation in the present study since several parameters in the feedstock mixture come into interplay during ***,binders,blending ratio,particle size,and principle feedstock material were the parameters of our interest in finding their effect on physical and thermochemical *** is also an endeavor to investigate low cost binder options in producing composite pellets of high quality.A Taguchi L9 orthogonal array experimental design was employed and Taguchi based Grey relational analysis was performed to determine the best combinatorial optimization of factor levels settings for producing best *** optimal parameter level settings for pelletization was determined to be 3.18 mm wheat feedstock material blended with pine shavings at 60/40 *** analysis of variance(ANOVA)was conducted to identify the contribution of each *** magnitude of the significant impacts of parameters on performance characteristics were in the order of binder>blend ratio>grind>feedstock *** also showed that the physico-chemical characteristics of the pellets were concomitant with the proportion of ingredients or recipes in a blend.

关键词： Agricultural waste Crop residues Optimization Pelletization Grey relational analysis Taguchi analysis Agricultural waste management Resource conversions and conservation Waste conversion into resource

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Epidemiologic investigation of pediatric distal humerus fractures: An American insurance claims database study

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World Journal of Orthopedics 2024年第1期15卷 52-60页

作者： Kyle Jay Klahs Jake E Dertinger Grant T Mello Kevin thapa Alexis B Sandler E'Stephan J Jesus Garcia Nata Parnes Department of Orthopaedic Surgery Texas Tech University Health Sciences-El PasoEl PasoTX 79905United States Medical School California Health Sciences University College of Osteopathic MedicineClovisCA 93611United States Undergraduate School Binghampton UniversityVestalNY 13902United States Department of Orthopaedic Surgery William Beaumont Army Medical CenterFort BlissTX 79918United States Department of Orthopaedic Surgery Carthage Area HospitalCarthageNY 13619United States

BACKGROUND Distal humerus elbow fractures are one of the most common traumatic fractures seen in pediatric patients and present as three main types:Supracondylar(SC),lateral condyle(LC),and medial epicondyle(ME)*** To evaluate the epidemiology of pediatric distal humerus fractures(SC,LC,and ME)from an American insurance claims *** A retrospective review was performed on patients 17 years and younger with the ICD 9 and 10 codes for SC,LC and ME fractures based on the IBM Truven MarketScan®Commercial and IBM Truven MarketScan Medicare Supplemental *** from 2015 to 2020 were queried for treatments,patient age,sex,length of hospitalization,and *** A total of 1133 SC,154 LC,and 124 ME fractures were *** fractures had the highest percentage of operation at 83%,followed by LC(78%)and ME fractures(41%).Male patients were,on average,older than female patients for both SC and ME *** In the insurance claims databases used,SC fractures were the most reported,followed by LC fractures,and finally ME *** was identified to be a factor for how a pediatric distal humerus fractures,with patients with SC and LC fractures being younger than those with ME *** peak age per injury per sex was similar to reported historic central tendencies,despite reported trends for younger physiologic development.

关键词： Supracondylar humerus fracture Lateral condyle fracture Medial epicondyle fracture Pediatric elbow Truven Epidemiology

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