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谈跨文化交际中的礼貌问题

中国职业技术教育 2006年第20期22卷 51-52页

作者：张红关淑云沧州师专河北沧州061001

礼貌具有文化差异性。这种差异性常会构成跨文化交际中的障碍。本文分析了中、西方礼貌文化的差异,并指出礼貌原则的相对性和复杂性,并在此基础上讨论了外语教学中应如何培养学生的跨文化交际能力。

关键词：跨文化交际文化差异礼貌原则语用学高等职业教育英语教学

A novel treatment workflow of idiopathic hypereosinophilic syndrome:a single-center retrospective cohort study

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Chinese Medical Journal 2022年第21期135卷 2602-2604页

作者： Rui Tang Shubin Lei shuyun Wang Yuanyuan guan Hong Li Department of Allergy Peking Union Medical College Hospital(PUMCH)Chinese Academy of Medical Sciences and Peking Union Medical College(CAMS and PUMC)Beijing 100730China Eight-Year Program of Clinical Medicine PUMCHCAMS and PUMCBeijing 100730China Department of Allergy The First Affiliated Yantai Yuhuangding Hospital of Qingdao UniversityYantaiShandong 264099China Department of Allergy The First Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150007China

Hypereosinophilic syndrome(HES),a rare systemic disease,was first described in *** a subtype of HES,idiopathic hypereosinophilic syndrome(IHES)is defined as hypereosinophilia of unknown cause,excluding tumor,infection,allergy,and immune system *** most cases,more than 1 organ is affected in patients with IHES.[1]The first-line drug for the treatment of IHES is glucocorticoid,which is effective for both hypereosinophilia and clinical manifestations.[2]However,when the outcome of hormone treatment is unsatisfactory,immunosuppressive or antineoplastic agents can also be administered.

关键词： eosinophilic treatment idiopathic

Function toggle of tumor microenvironment responsive nanoagent for highly efficient free radical stress enhanced chemodynamic therapy

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Nano Research 2022年第9期15卷 8228-8236页

作者： Xueting Yang Shuaitian Guo Li Wang Shanyue guan shuyun Zhou Jun Lu State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100190China Beijing Advanced Innovation Center for Soft Mater Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China

In contrast to reactive oxygen species(ROS),the generation of oxygen-irrelevant free radicals is oxygen-and H2O2-independent in cell,which can offer novel opportunities to maximum the chemodynamic therapy(CDT)***,an H2O2-independent“functional reversion”strategy based on tumor microenvironment(TME)-toggled C-free radical generation for CDT is developed by confining astaxanthin(ATX)on the NiFe-layered double hydroxide(LDH)nanosheets(denoted as ATX/LDH).The unique ATX/LDH can demonstrate outstanding TME-responsive C-free radical generation performance by proton coupled electron transfer(PCET),owing to the specific ATX activation by unsaturated Fe sites on the LDH nanosheets formed under ***,the Brönsted base sites of LDH hydroxide layers can promote the generation of neutral ATX C-free radicals by capturing the protons generated in the ATX activation ***,ATX/LDH maintain antioxidant performance to prevent normal tissue cancerization due to the synergy of LDH nanosheets and antioxidative *** addition,C-free radical can compromise the antioxidant defense in cells to the maximum extent,compared with *** free radicals burst under TME can significantly elevate free radical stress and induce cancer cell *** strategy can realize TME-toggled C free radical generation and perform free radical stress enhanced CDT.

关键词： ultrathin layered double hydroxide nanosheets astaxanthin free radical chemodynamic therapy

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超高分子量聚乙烯纤维的耐高温性能

现代纺织技术 2024年第3期32卷 53-60页

作者：薛淑云叶伟王征夏平原管永银扬州斯帕克实业有限公司江苏扬州225200 南通大学安全防护用特种纤维复合材料研发国家地方联合工程研究中心江苏南通226019 中国人民解放军军事科学院国防工程研究院北京100036 江苏正道海洋科技有限公司江苏南通226300 新凤鸣集团湖州中石科技有限公司浙江湖州313000

针对超高分子量聚乙烯(UHMWPE)纤维熔点低、易蠕变的缺点,以复合材料热压加工环境为测试条件,通过分析不同热压温度和热压时间下的力学稳定性能,研究UHMWPE纤维的耐高温性能。采用差示扫描量热仪、热重分析仪、扫描电子显微镜、X射线衍... 详细信息

针对超高分子量聚乙烯(UHMWPE)纤维熔点低、易蠕变的缺点,以复合材料热压加工环境为测试条件,通过分析不同热压温度和热压时间下的力学稳定性能,研究UHMWPE纤维的耐高温性能。采用差示扫描量热仪、热重分析仪、扫描电子显微镜、X射线衍射仪、红外吸收光谱分析仪和力学性能测试仪等仪器设备,表征并分析了UHMWPE纤维的力学性能、热稳定性能和微观结构。结果表明:热压温度及时间对UHMWPE纤维性能有着重要的影响。在150℃及以下热压处理时,纤维力学性能随着热压时间的增加而变化不大;在160℃及以上热压处理时,长时间的热处理导致纤维力学性能下降明显,在160℃处理40 s时丝束断裂强力为153 N,强力损失为46.50%;当热压温度大于纤维熔点时,纤维强力出现急速下降,在170℃热压处理10 s时强力下降到了121 N,强力损失达到了57.80%。研究结果可为UHMWPE纤维复合材料的加工及应用提供参考。

关键词：超高分子量聚乙烯纤维热稳定性能断裂强力断裂伸长高性能纤维

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Targeted alleviation of ischemic stroke reperfusion via atorvastatin-ferritin Gd-layered double hydroxide

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Bioactive Materials 2023年第2期20卷 126-136页

作者： Li Wang Baorui Zhang Xueting Yang Shuaitian Guo Geoffrey I.N.Waterhouse guangrong Song Shanyue guan Aihua Liu Liang Cheng shuyun Zhou Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing100190China Beijing Neurosurgical Institute and Beijing Tiantan Hospital Capital Medical UniversityChina National Clinical Research Center for Neurological DiseasesBeijing100070China Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou215123China School of Chemical Sciences The University of AucklandAuckland1142New Zealand

In acute ischemic stroke therapy,potent neuroprotective agents are needed that prevent neural injuries caused by reactive oxygen species(ROS)during ischemic ***,a novel 2D neuroprotective agent(AFGd-LDH)is reported,comprising Gd-containing layered double hydroxide nanosheets(Gd-LDH,as a drug nanocarrier/MRI contrast agent),atorvastatin(ATO,as a neuroprotective drug)and the ferritin heavy subunit(FTH,as a blood brain barrier transport agent).Experiments revealed AFGd-LDH to possess outstanding antioxidant activity,neuroprotective properties,blood‒brain barrier transit properties,and *** vitro studies demonstrated the ROS scavenging efficiency of AFGd‒LDH to be~90%,surpassing CeO_(2)(50%,a ROS scavenger)and edaravone(52%,a clinical neuroprotective drug).Ischemia‒reperfusion model studies in mice showed AFGd‒LDH could dramatically decrease apoptosis induced by reperfusion,reducing the infarct area by 67%and lowering the neurological deficit score from 3.2 to ***-LDH also offered outstanding MRI performance,thus enabling simultaneous imaging and ischemia reperfusion therapy.

关键词： Layered double hydroxide ROS scavenger Atorvastatin Ischemic stroke Multimodal imaging

Photogenerated-hole-induced rapid elimination of solid tumors by the supramolecular porphyrin photocatalyst

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National Science Review 2021年第5期8卷 101-109页

作者： Zijian Zhang Li Wang Weixu Liu Zihe Yan Yongfa Zhu shuyun Zhou Shanyue guan Department of Chemistry Tsinghua University Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of Sciences

The rapid, complete, targeted and safe treatment for tumors remains a key issue in cancer therapy. A novel treatment of solid tumors by supramolecular photocatalyst Nano-SA-TCPP with the irradiation of600–700 nm wavelength is established. Solid tumors(100 mm3) can be eliminated within 10 min. The50-day mouse survival rate was increased from 0% to 100% after the photocatalytic therapy. The breakthrough was owing to the cell membrane rupture and the cytoplasmic loss caused by photogenerated holes inside cancer cells. The porphyrin-based photocatalysts can be internalized in a targeted manner by cancer cells due to the size selection effect, without entering the normal cells. The therapy has no toxicity or side effects for normal cells and organisms. Moreover, the photocatalytic therapy is effective for a variety of cancer cell lines. Because of its high efficiency, safety and universality, the photocatalytic therapy provides us with a new lancet to conquer the tumor.

关键词： supramolecular photocatalyst photogenerated holes solid tumor rapid elimination red light

The Liaonan Metamorphic Core Complex: Constitution, Structure and Evolution

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Acta Geologica Sinica(English Edition) 2006年第4期80卷 502-513页

作者： LIU Junlai guan Huimei JI Mo CAO shuyun HU Ling State Key Laboratory of Geological Processes and Mineral Resources and Key Laboratory of Lithosphere Tectonics and Lithoprobing Technology of the Ministry of Education China University of Geosciences Beijing 100083

The Liaonan metamorphic core complex （mcc） has a three-layer structure and is constituted by five parts, i.e. a detachment fault zone, an allochthonous upper plate and an supradetachment basin above the fault zone, and highly metamorphosed rocks and intrusive rocks in the lower plate. The allochthonous upper plate is mainly of Neoproterozoic and Paleozoic rocks weakly deformed and metamorphosed in pre-Indosinan stage. Above these rocks is a small-scale supradetachment basin of Cretaceous sedimentary and volcanic rocks. The lower plate is dominated by Archean TTG gneisses with minor amount of supracrustal rocks. The Archean rocks are intruded by late Mesozoic synkinematic monzogranitic and granitic plutons. Different types of fault rocks, providing clues to the evolution of the detachment fault zone, are well-preserved in the fault zone, e.g. mylonitic gneiss, mylonites, brecciated mylonites, microbreccias and pseudotachylites. Lineations in lower plate granitic intrusions have consistent orientation that indicate uniform top-to-NW shearing along the main detachment fault zone. This also provides evidence for the synkinematic characteristics of the granitic plutons in the lower plate. Structural analysis of the different parts in the mcc and isotopic dating of plutonic rocks from the lower plate and mylonitic rocks from detachment fault zone suggest that exhumation of the mcc started with regional crustal extension due to crustal block rotation and tangential shearing. The extension triggered magma formation, upwelling and emplacement. This event ended with appearance of pseudotachylite and fault gauges formed at the uppermost crustal level. U-Pb dating of single zircon grains from granitic rocks in the lower plate gives an age of 130±2.5 Ma, and biotite grains from the main detachment fault zone have ^40Ar-^39Ar ages of 108-119 Ma. Several aspects may provide constraints for the exhumation of the Liaonan mcc. These include regional extensional setting, cover/basemen

关键词： Liaonan metamorphic core complex crustal and lithosphere thinning crustal extension late Mesozoic

Therapies for children with cerebral palsy A Web of Science-based literature analysis

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Neural Regeneration Research 2012年第33期7卷 2632-2639页

作者： Yaping Mu Na Li Lijun guan Chunnan Wang shuyun Shang Yan Wang Shenyang Children's Hospital Shenyang 110032 Liaoning Province China

OBJECTIVE： To identify global research trends in three therapies for children with cerebral palsy. DATA RETRIEVAL： We performed a bibliometric analysis of studies on therapies for children with cerebral palsy from 2002 to 2011 retrieved from Web of Science. SELECTION CRITERIA： Inclusion criteria：（a） peer-reviewed published articles on botulinum toxin, constraint-induced movement therapy, or acupuncture for children with cerebral palsy indexed in Web of Science; （b） original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items; and （c） publication between 2002 and 2011. Exclusion criteria：（a） articles that required manual searching or telephone access; （b） documents that were not published in the public domain; and （c） a number of corrected papers from the total number of articles. MAIN OUTCOME MEASURES：（1） Number of publications on the three therapies; （2） annual publication output, distribution by journals, distribution by institution, and top-cited articles on botulinum toxin; （3） annual publication output, distribution by journal, distribution by institution, and top-cited articles on constraint-induced movement therapy; （4） annual publication, distribution by journal, distribution by institution, and top-cited articles on acupuncture. RESULTS： This analysis, based on Web of Science articles, identified several research trends in studies published over the past 10 years of three therapies for children with cerebral palsy. More articles on botulinum toxin for treating children with cerebral palsy were published than the articles regarding constraint-induced movement therapy or acupuncture. The numbers of publications increased over the 10-year study period. Most papers appeared in journals with a focus on neurology, such as Developmental Medicine and Child Neurology and Journal of Child *** institutes publishing on botulinum toxin treatments for this population are mostly in the Neth

关键词： constraint-induced movement therapy botulinum toxin acupuncture cerebral palsy nerve injury infant children brain Web of Science bibliometric neural regeneration

基于多元化学模式识别分析的生姜UPLC指纹图谱研究

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中国药师 2022年第7期25卷 1173-1178页

作者：宋叶罗宇琴李国卫赵书运官永河杜兰哲广东一方制药有限公司广东省中药配方颗粒企业重点实验室广东佛山528244

目的:建立生姜UPLC指纹图谱研究方法,通过多元化学模式识别分析,为生姜药材的质量控制提供参考。方法:采用Acclaim C_(18)(2.1 mm×100 mm,2.2μm)色谱柱,流动相为甲醇-乙腈-水,梯度洗脱,检测波长为280 nm,流速为0.4 ml·min^(-1),柱温... 详细信息

目的:建立生姜UPLC指纹图谱研究方法,通过多元化学模式识别分析,为生姜药材的质量控制提供参考。方法:采用Acclaim C_(18)(2.1 mm×100 mm,2.2μm)色谱柱,流动相为甲醇-乙腈-水,梯度洗脱,检测波长为280 nm,流速为0.4 ml·min^(-1),柱温为30℃,建立不同产地的生姜指纹图谱,利用总量统计矩分析、相似度评价、聚类分析、主成分分析和偏最小二乘判别分析等多元化学计量方法对生姜进行质量评价。结果:建立了18批生姜样品指纹图谱,确定了13个共有峰,18批样品相似度均大于0.9。经过聚类分析,18批生姜样品可聚为两类,采用主成分分析确定3个主成分为影响药材样品质量评价的主要因子;13个共有峰中对样品组分起关键作用的成分为峰3(6-姜辣素)、峰7、峰9、峰10、峰11、峰12。结论:利用UPLC法建立的生姜药材指纹图谱准确,可有效评价生姜药材的质量。

关键词：生姜总量统计矩分析聚类分析主成分分析偏最小二乘判别分析