检索结果-南通市图书馆

Crosstalk between adipose-derived stem cells and chondrocytes:when growth factors matter

在线全文

学校读者我要写书评

暂无评论

Bone Research 2015年第4期3卷 216-225页

作者： Juan Zhong Bin Guo Jing Xie shuwen deng Na Fu Shiyu Lin Guo Li Yunfeng Lin Xiaoxiao Cai State Key Laboratory of Oral Diseases West China Hospital of StomatologySichuan University Institute of Stomatology General Hospital of Chinese PLA

Adipose-derived stem cells（ASCs）and mesenchymal stem cells are promising for tissue repair because of their multilineage differentiation *** previous data confirmed that the implantation of mixed ASCs and chondrocytes into cartilage defects induced desirable in vivo healing ***,the paracrine action of ASCs on chondrocytes needs to be further *** this study,we established a co-culture system to achieve cell-to-cell and cell-to-tissue crosstalk and explored the soluble growth factors in both ASCs and chondrocytes supplemented with 1%fetal bovine serum to mimic the physiological *** ASCs,we screened for growth factors by semi-quantitative PCR and quantitative real-time PCR and found that the expression of bone morphogenetic protein 2（BMP-2）,vascular endothelial growth factor B（VEGFB）,hypoxia inducible factor-1α（HIF-1α）,fibroblast growth factor-2（FGF-2）,and transforming growth factor-β1 significantly increased after co-culture in comparison with *** chondrocytes,VEGFA was significantly enhanced after ***,the expression of collagen II and aggrecan was significantly down-regulated in the co-culture group compared with the mono-culture ***,among all the growth factors screened,we found that the BMP family members BMP-2,BMP-4,and BMP-5 were down-regulated and that VEGFB,HIF-1α,FGF-2,and PDGF were significantly decreased after *** results suggest that crosstalk between ASCs and chondrocytes is a pathway through the regulated growth factors that might have potential in cartilage repair and regeneration and could be useful for tissue engineering.

关键词： crosstalk cartilage adipose repair Forward physiological morphogenetic elucidated fetal mimic

Analysis and Prediction Model Reinforced UHPC Shrinkage Property

在线全文

学校读者我要写书评

暂无评论

Journal of Architectural Research and Development 2024年第2期8卷 99-107页

作者： shuwen deng Zhiming Huang Hao Chen Jia Hu Hunan Construction Investment Group Changsha 410026China College of Water Resources and Civil Engineering Hunan Agricultural UniversityChangsha 410128China Key Laboratory for Wind and Bridge Engineering of Hunan Province School of Civil EngineeringHunan UniversityChangsha 410082China

This paper explores the shrinkage of reinforced UHPC under high-temperature steam curing and natural curing *** results are compared with the existing shrinkage prediction *** results show that the maximum shrinkage strain of reinforced UHPC after steam curing is 164μεand gradually becomes *** for natural curing,the maximum shrinkage strain is 173μεand the value stabilizes on the 10th day after *** indicated that steam curing can significantly reduce shrinkage *** with the plain UHPC tested in the previous literature,the structural reinforcement can significantly inhibit the UHPC shrinkage and greatly reduce the risk of cracking due to *** comparing the results in this paper with the existing models for predicting the shrinkage strain development,it is found that the formula recommended in the French UHPC structural and technical specification is suitable for the shrinkage curve in the present paper.

关键词： Ultra-high performance concrete(UHPC) UHPC shrinkage Reinforced UHPC slab Shrinkage prediction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

UHPC-NC组合构件界面行为研究

重庆大学学报 2021年第3期44卷 63-74页

作者：欧阳娜邓舒文江西省公路科研设计院南昌330002 湖南大学土木工程学院长沙410082

随UHPC材料兴起,现已有较多研究表明将UHPC材料应用于结构接缝处可极大程度地增强结构的整体性能,接缝界面处的粘结强度也逐渐引起学术界关注。然而,如何对结合面处进行有效的有限元模拟却始终未见统一有效的方式。文章在广泛的文献调... 详细信息

随UHPC材料兴起,现已有较多研究表明将UHPC材料应用于结构接缝处可极大程度地增强结构的整体性能,接缝界面处的粘结强度也逐渐引起学术界关注。然而,如何对结合面处进行有效的有限元模拟却始终未见统一有效的方式。文章在广泛的文献调研基础上,总结现有试验数据,对比试验方法,得到3种不同粗糙度界面粘聚力分别为2.24 MPa,2.37 MPa和2.66 MPa,3种界面摩擦系数分别为1.42,1.63和1.64;提出基于粘聚力和抗剪强度的UHPC-NC界面强度计算式;基于接触分离模型分别建立适用于受拉为主构件及压剪为主构件的3D有限元模型,提出适用于光滑界面、中等粗糙界面及粗糙界面的粘聚力参数、接触损伤相关参数;为验证有限元参数有效性,建立多个文献试验有限元模型并与结果对比较为吻合,可为后期有限元计算提供参考。

关键词： UHPC-NC组合构件界面粘聚力摩擦系数接触分离模型

A re-evaluation of the Chaetothyriales using criteria of comparative biology

在线全文

学校读者我要写书评

暂无评论

Fungal Diversity 2020年第4期103卷 47-85页

作者： Yu Quan Lucia Muggia Leandro F.Moreno Meizhu Wang Abdullah M.S.Al-Hatmi Nickolas da Silva Menezes Dongmei Shi shuwen deng Sarah Ahmed Kevin D.Hyde Vania A.Vicente Yingqian Kang JBenjamin Stielow Sybren de Hoog Centre of Expertise in Mycology of Radboud University Medical Centre/Canisius Wilhelmina Hospital NijmegenThe Netherlands Key Laboratory of Environmental Pollution Monitoring and Disease Control Ministry of Education of Guizhou&Key Laboratory of Medical Microbiology and ParasitologySchool of Basic Medical SciencesGuizhou Medical UniversityGuiyangChina College of Food and Pharmaceutical Engineering Guizhou Institute of TechnologyGuiyangChina Department of Life Sciences University of TriesteTriesteItaly Amsterdam Medical Center AmsterdamThe Netherlands Foundation Atlas of Clinical Fungi HilversumThe Netherlands Ministry of Health Directorate General of Health ServicesIbriOman Postgraduate Program in Microbiology Parasitology and PathologyBiological SciencesDepartment of Basic PathologyFederal University of ParanaCuritibaBrazil Department of Dermatology&Laboratory of Medical Mycology Jining No.1 People’s HospitalJiningShandongChina Department of Medical Microbiology People’s Hospital of Suzhou National New&Hi-Tech Industrial Development ZoneSuzhouChina Center of Excellence in Fungal Diversity Mae Fah Luang UniversityChiang RaiThailand Thermo Fisher Diagnostics Specialty Diagnostics GroupLandsmeerThe Netherlands Guizhou Academy of Tobacco Science GuiyangChina Engineering Bioprocess and Biotechnology Post-graduation Program Department of Bioprocess Engineering and BiotechnologyFederal University of ParanaCuritibaBrazil

Chaetothyriales is an ascomycetous order within *** order is particularly known through the black yeasts and filamentous relatives that cause opportunistic infections in *** species in the order are consistently *** and habitats of species are highly diverse,and often rather extreme in terms of exposition and *** are defined on the basis of evolutionary history,which is reconstructed by time of divergence and concepts of comparative biology using stochastical character mapping and a multi-rate Brownian motion model to reconstruct ecological ancestral character *** is hypothesized to be with a rock-inhabiting life *** disparity increased significantly in late Jurassic,probably due to expansion of cytochromes followed by colonization of vacant *** diversification took place subsequently,but at a low level of innovation resulting in strong niche conservatism for extant *** are ecologically different in degrees of *** of the clades has adapted ant domatia,which are rich in *** derived families,similar processes have enabled survival in domesticated environments rich in creosote and toxic hydrocarbons,and this ability might also explain the pronounced infectious ability of vertebrate hosts observed in these *** systems of morphological classification poorly correspond with recent phylogenetic *** are hypothesized to have low competitive ability against neighboring microbes,which interferes with their laboratory isolation on routine *** dataset is unbalanced in that a large part of the extant biodiversity has not been analyzed by molecular methods,novel taxonomic entities being introduced at a regular *** study comprises all available species sequenced to date for LSU and ITS,and a nomenclatural overview is provided.A limited number of species could not be assigned to any extant family.

关键词： Black yeasts Phylogeny Ecology Ancestral reconstruction Evolution Nomenclature

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

从类型学看现代汉语冠词的词类地位

外国语 2022年第4期45卷 51-60页

作者：罗天华邓舒文浙江大学文学院/国家语言文字推广基地浙江杭州310058

现代汉语有无冠词,学界争议颇多。本文结合冠词的跨语言定义及其与指示词、量词的区分标准,讨论了现代汉语冠词立类的形式、语义和历时依据,认为弱读的“这”和“个”已不用作指示词和量词,而具备了相当的冠词特点,应予单独立类。冠词... 详细信息

现代汉语有无冠词,学界争议颇多。本文结合冠词的跨语言定义及其与指示词、量词的区分标准,讨论了现代汉语冠词立类的形式、语义和历时依据,认为弱读的“这”和“个”已不用作指示词和量词,而具备了相当的冠词特点,应予单独立类。冠词立类合乎汉语事实,并可避免一些不必要的分析混乱。文章也讨论了相关的“那”和“一”“一个”,认为它们尚未发展为冠词。

关键词：词类冠词限定词指示词变调

形态的意义与表达方式--评江荻的《藏语词法和形态》

在线全文

学校读者我要写书评

暂无评论

民族语文 2022年第5期 122-128页

作者：罗天华邓舒文浙江大学文学院/国家语言文字推广基地杭州310058

在宏观的形态学视野下,《藏语词法和形态》以词法表现形式为切入点,探讨词法和词库、词类和词法的种种关联,揭示了藏语派生、屈折、重叠、复合等词法面貌。该书认为复合是藏语的重要构词方式,内部形类语素间蕴含施事、受事、工具等语义... 详细信息

在宏观的形态学视野下,《藏语词法和形态》以词法表现形式为切入点,探讨词法和词库、词类和词法的种种关联,揭示了藏语派生、屈折、重叠、复合等词法面貌。该书认为复合是藏语的重要构词方式,内部形类语素间蕴含施事、受事、工具等语义关系,并将词长视为形态表现;所提“音节数形态”“词形分类、词类分形”等论断均体现出藏语形态表达方式的多样性,丰富了形态学的一般理论。本文尝试概述该书的主要观点,并评析一些论述的优长及其对跨语言形态研究的启示。

关键词：藏语形态词法形态意义表达方式

林业碳汇信贷融资现实困境、制约因素与模式创新

在线全文

学校读者我要写书评

暂无评论

中国人口·资源与环境 2024年第3期34卷 68-78页

作者：秦涛王姗邓树文朱然北京林业大学经济管理学院北京100083

林业碳汇信贷融资作为林业碳汇价值实现的主要路径,对于盘活林业碳汇资源、提升碳汇资产价值,以及缓解碳汇经营企业融资约束具有重要价值。目前,中国部分地区已探索试点林业碳汇质押融资业务,但面临现有模式难以复制推广的现实困境。该... 详细信息

林业碳汇信贷融资作为林业碳汇价值实现的主要路径,对于盘活林业碳汇资源、提升碳汇资产价值,以及缓解碳汇经营企业融资约束具有重要价值。目前,中国部分地区已探索试点林业碳汇质押融资业务,但面临现有模式难以复制推广的现实困境。该研究通过剖析典型案例的融资模式和现存不足,深入分析林业碳汇信贷融资当下面临的现实问题,探究影响林业碳汇发挥质押作用的根本原因。研究发现:①林业碳汇法律属性不明确,质权设立过程中涉及的相关权益变动缺乏法理依据。②林业碳汇价值评估标准缺失,质押价值评估结果银行难以认定。③林业碳汇资产质权难以处置变现,质权实现路径缺失导致银行无法有效控制信贷违约风险。因此,该研究通过引入林业碳汇保险的保单质押、价值认定和金融增信功能,以及碳汇收储机制在质权实现方面的担保增信作用,创新性地提出“林权抵押附加林业碳汇(预期收益权)质押+碳汇价值综合保险+林权(碳汇)收储担保”“林业碳汇(预期收益权)价值保险保单质押+碳汇收储担保”和“林业碳汇资产质押+碳汇价格指数保险”三种林业碳汇信贷融资模式,为林业碳汇质押融资广泛开展提供可行路径。最后,针对林业碳汇信贷融资的制约因素,从完善碳汇相关配套政策、统一碳汇价值评估标准、优化创新碳汇保险产品、建立碳汇收储担保制度、构建林业碳汇金融支持体系五个方面,提出促进林业碳汇信贷融资有效开展的具体策略建议。

关键词：林业碳汇信贷质押担保保险融资

维普期刊数据库博看期刊

事务所合并可以提高审计质量吗?——基于中国审计市场的研究

在线全文

学校读者我要写书评

暂无评论

管理世界 2010年第12期26卷 180-181页

作者：王咏梅邓舒文北京大学光华管理学院会计系

本文基于中国会计师事务所行业轮番而至的合并浪潮,从市场集中度和合并的交易成本两个角度,分析研究了事务所之间的合并对审计质量的影响。研究表明,事务所合并改善了行业的市场结构,但因为交易成本的存在等多方面的因素,并没有观察到... 详细信息

本文基于中国会计师事务所行业轮番而至的合并浪潮,从市场集中度和合并的交易成本两个角度,分析研究了事务所之间的合并对审计质量的影响。研究表明,事务所合并改善了行业的市场结构,但因为交易成本的存在等多方面的因素,并没有观察到合并导致的审计质量提高的现象。

关键词：外部审计会计师事务审计质量

在线全文

学校读者我要写书评

暂无评论

轻型组合桥梁负弯矩区接缝抗弯性能试验

浙江大学学报（工学版） 2024年第2期58卷 399-412页

作者：邓舒文邵旭东晏班夫邱明红湖南农业大学水利与土木工程学院湖南长沙410125 湖南大学土木工程学院湖南长沙410082 广西大学土木建筑工程学院广西南宁530004 香港大学土木工程系中国香港999077

对适用于轻型组合桥梁负弯矩区的T形横向接缝抗弯性能进行试验研究,对负弯矩加载接缝的全过程进行理论分析,对接缝设计参数进行讨论.研究结果表明,随着荷载的增大,试件的主裂缝出现在连续浇筑的UHPC接缝界面和加载点下方的面板表面,试... 详细信息

对适用于轻型组合桥梁负弯矩区的T形横向接缝抗弯性能进行试验研究,对负弯矩加载接缝的全过程进行理论分析,对接缝设计参数进行讨论.研究结果表明,随着荷载的增大,试件的主裂缝出现在连续浇筑的UHPC接缝界面和加载点下方的面板表面,试件中部未发现明显裂纹,UHPC接缝界面的可视初裂强度可以满足实桥设计荷载.对试验梁进行分析,提出接缝最大裂缝宽度、考虑UHPC拉伸刚度效应的设计弯矩和挠度计算公式,获得每阶段承载力的计算式,预测结果与试验结果吻合良好.通过参数讨论和计算可知,跨度L=20~50 m的轻型组合桥梁T形接缝上部加长长度可以设置为0.1L.

关键词：超高性能混凝土(UHPC) UHPC接缝抗弯性能试验裂缝宽度计算式挠度计算式极限承载力计算式